 Neoplasm Proteins
"Neoplasm Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (TUMOR MARKERS, BIOLOGICAL) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
| Descriptor ID |
D009363
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| MeSH Number(s) |
D12.776.624
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neoplasm Proteins".
Below are MeSH descriptors whose meaning is more specific than "Neoplasm Proteins".
This graph shows the total number of publications written about "Neoplasm Proteins" by people in this website by year, and whether "Neoplasm Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1980 | 1 | 0 | 1 | | 1982 | 2 | 1 | 3 | | 1983 | 0 | 1 | 1 | | 1985 | 1 | 1 | 2 | | 1986 | 1 | 0 | 1 | | 1987 | 3 | 1 | 4 | | 1988 | 2 | 0 | 2 | | 1989 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1992 | 2 | 1 | 3 | | 1993 | 1 | 2 | 3 | | 1994 | 2 | 3 | 5 | | 1995 | 4 | 4 | 8 | | 1996 | 6 | 3 | 9 | | 1997 | 3 | 3 | 6 | | 1998 | 3 | 1 | 4 | | 1999 | 5 | 5 | 10 | | 2000 | 8 | 15 | 23 | | 2001 | 9 | 3 | 12 | | 2002 | 12 | 5 | 17 | | 2003 | 17 | 4 | 21 | | 2004 | 12 | 8 | 20 | | 2005 | 8 | 5 | 13 | | 2006 | 7 | 10 | 17 | | 2007 | 9 | 8 | 17 | | 2008 | 13 | 4 | 17 | | 2009 | 5 | 9 | 14 | | 2010 | 5 | 7 | 12 | | 2011 | 8 | 6 | 14 | | 2012 | 9 | 10 | 19 | | 2013 | 10 | 8 | 18 | | 2014 | 9 | 6 | 15 | | 2015 | 10 | 8 | 18 | | 2016 | 8 | 4 | 12 | | 2017 | 5 | 2 | 7 | | 2018 | 9 | 4 | 13 | | 2019 | 8 | 8 | 16 | | 2020 | 10 | 3 | 13 | | 2021 | 4 | 1 | 5 |
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Below are the most recent publications written about "Neoplasm Proteins" by people in Profiles.
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Yesilkanal AE, Johnson GL, Ramos AF, Rosner MR. New strategies for targeting kinase networks in cancer. J Biol Chem. 2021 10; 297(4):101128.
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Dasgupta A, Chen KH, Lima PDA, Mewburn J, Wu D, Al-Qazazi R, Jones O, Tian L, Potus F, Bonnet S, Archer SL. PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension. FASEB J. 2021 08; 35(8):e21771.
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Capece D, D'Andrea D, Begalli F, Goracci L, Tornatore L, Alexander JL, Di Veroli A, Leow SC, Vaiyapuri TS, Ellis JK, Verzella D, Bennett J, Savino L, Ma Y, McKenzie JS, Doria ML, Mason SE, Chng KR, Keun HC, Frost G, Tergaonkar V, Broniowska K, Stunkel W, Takats Z, Kinross JM, Cruciani G, Franzoso G. Enhanced triacylglycerol catabolism by carboxylesterase 1 promotes aggressive colorectal carcinoma. J Clin Invest. 2021 06 01; 131(11).
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Singhal SS, Mohanty A, Kulkarni P, Horne D, Awasthi S, Salgia R. RLIP depletion induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells. Carcinogenesis. 2021 05 28; 42(5):742-752.
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Berardi DE, Ariza Bareño L, Amigo N, Cañonero L, Pelagatti MLN, Motter AN, Taruselli MA, Díaz Bessone MI, Cirigliano SM, Edelstein A, Peters MG, Diament M, Urtreger AJ, Todaro LB. All-trans retinoic acid and protein kinase C a/ß1 inhibitor combined treatment targets cancer stem cells and impairs breast tumor progression. Sci Rep. 2021 03 15; 11(1):6044.
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White MG, Schulte JJ, Xue L, Berger Y, Schuitevoerder D, Vining CC, Kindler HL, Husain A, Turaga KK, Eng OS. Heterogeneity in PD-L1 expression in malignant peritoneal mesothelioma with systemic or intraperitoneal chemotherapy. Br J Cancer. 2021 02; 124(3):564-566.
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Bennett SL, Basko-Plluska JL, Shea CR, Bolotin D. Role of Wnt signaling in dermatofibroma induction phenomenon. J Cutan Pathol. 2021 Feb; 48(2):217-220.
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Saoud R, Heidar NA, Cimadamore A, Paner GP. Incorporating Prognostic Biomarkers into Risk Assessment Models and TNM Staging for Prostate Cancer. Cells. 2020 09 17; 9(9).
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Garcia-Manero G, Griffiths EA, Steensma DP, Roboz GJ, Wells R, McCloskey J, Odenike O, DeZern AE, Yee K, Busque L, O'Connell C, Michaelis LC, Brandwein J, Kantarjian H, Oganesian A, Azab M, Savona MR. Oral cedazuridine/decitabine for MDS and CMML: a phase 2 pharmacokinetic/pharmacodynamic randomized crossover study. Blood. 2020 08 06; 136(6):674-683.
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Huang LS, Kotha SR, Avasarala S, VanScoyk M, Winn RA, Pennathur A, Yashaswini PS, Bandela M, Salgia R, Tyurina YY, Kagan VE, Zhu X, Reddy SP, Sudhadevi T, Punathil-Kannan PK, Harijith A, Ramchandran R, Bikkavilli RK, Natarajan V. Lysocardiolipin acyltransferase regulates NSCLC cell proliferation and migration by modulating mitochondrial dynamics. J Biol Chem. 2020 09 18; 295(38):13393-13406.
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