 Sex Hormone-Binding Globulin
"Sex Hormone-Binding Globulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
| Descriptor ID |
D012738
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| MeSH Number(s) |
D12.776.124.790.223.800 D12.776.157.762 D12.776.377.715.182.800
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| Concept/Terms |
Sex Hormone-Binding Globulin- Sex Hormone-Binding Globulin
- Globulin, Sex Hormone-Binding
- Hormone-Binding Globulin, Sex
- Sex Hormone Binding Globulin
- Testosterone-Estradiol Binding Globulin
- Binding Globulin, Testosterone-Estradiol
- Globulin, Testosterone-Estradiol Binding
- Testosterone Estradiol Binding Globulin
- Sex Steroid-Binding Protein
- Sex Steroid Binding Protein
- Steroid-Binding Protein, Sex
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Below are MeSH descriptors whose meaning is more general than "Sex Hormone-Binding Globulin".
Below are MeSH descriptors whose meaning is more specific than "Sex Hormone-Binding Globulin".
This graph shows the total number of publications written about "Sex Hormone-Binding Globulin" by people in this website by year, and whether "Sex Hormone-Binding Globulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 1 | 0 | 1 | | 1982 | 0 | 1 | 1 | | 1983 | 0 | 2 | 2 | | 1988 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sex Hormone-Binding Globulin" by people in Profiles.
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Sarkar M, VanWagner LB, Terry JG, Carr JJ, Rinella M, Schreiner PJ, Lewis CE, Terrault N. Sex Hormone-Binding Globulin Levels in Young Men Are Associated With Nonalcoholic Fatty Liver Disease in Midlife. Am J Gastroenterol. 2019 05; 114(5):758-763.
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Kresovich JK, Argos M, Turyk ME. Associations of lead and cadmium with sex hormones in adult males. Environ Res. 2015 Oct; 142:25-33.
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Danielson KK, Drum ML, Lipton RB. Sex hormone-binding globulin and testosterone in individuals with childhood diabetes. Diabetes Care. 2008 Jun; 31(6):1207-13.
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Gapstur SM, Kopp P, Gann PH, Chiu BC, Colangelo LA, Liu K. Changes in BMI modulate age-associated changes in sex hormone binding globulin and total testosterone, but not bioavailable testosterone in young adult men: the CARDIA Male Hormone Study. Int J Obes (Lond). 2007 Apr; 31(4):685-91.
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Wu SY, Sadow PM, Refetoff S, Weiss RE. Tissue responses to thyroid hormone in a kindred with resistance to thyroid hormone harboring a commonly occurring mutation in the thyroid hormone receptor beta gene (P453T). J Lab Clin Med. 2005 Aug; 146(2):85-94.
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Sowers M, Crawford SL, Cauley JA, Stein E. Association of lipoprotein(a), insulin resistance, and reproductive hormones in a multiethnic cohort of pre- and perimenopausal women (The SWAN Study). Am J Cardiol. 2003 Sep 01; 92(5):533-7.
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Cameron LD, Leventhal H, Love RR, Patrick-Miller LJ. Trait anxiety and tamoxifen effects on bone mineral density and sex hormone- binding globulin. Psychosom Med. 2002 Jul-Aug; 64(4):612-20.
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Ghazi AA, Refetoff S. Evaluation of pituitary and peripheral tissue markers of thyroid hormone action in an Iranian family with resistance to thyroid hormone. Thyroid. 1996 Dec; 6(6):589-93.
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Baird DD, Umbach DM, Lansdell L, Hughes CL, Setchell KD, Weinberg CR, Haney AF, Wilcox AJ, Mclachlan JA. Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women. J Clin Endocrinol Metab. 1995 May; 80(5):1685-90.
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Sarne DH, Refetoff S, Rosenfield RL, Farriaux JP. Sex hormone-binding globulin in the diagnosis of peripheral tissue resistance to thyroid hormone: the value of changes after short term triiodothyronine administration. J Clin Endocrinol Metab. 1988 Apr; 66(4):740-6.
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