 Thymus Gland
"Thymus Gland" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single, unpaired primary lymphoid organ situated in the MEDIASTINUM, extending superiorly into the neck to the lower edge of the THYROID GLAND and inferiorly to the fourth costal cartilage. It is necessary for normal development of immunologic function early in life. By puberty, it begins to involute and much of the tissue is replaced by fat.
| Descriptor ID |
D013950
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| MeSH Number(s) |
A10.549.750 A15.382.520.604.750
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| Concept/Terms |
Thymus Gland- Thymus Gland
- Gland, Thymus
- Glands, Thymus
- Thymus Glands
- Thymus
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Below are MeSH descriptors whose meaning is more general than "Thymus Gland".
Below are MeSH descriptors whose meaning is more specific than "Thymus Gland".
This graph shows the total number of publications written about "Thymus Gland" by people in this website by year, and whether "Thymus Gland" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1981 | 0 | 2 | 2 | | 1983 | 1 | 1 | 2 | | 1984 | 0 | 1 | 1 | | 1985 | 0 | 1 | 1 | | 1990 | 2 | 1 | 3 | | 1991 | 1 | 2 | 3 | | 1992 | 0 | 2 | 2 | | 1993 | 1 | 2 | 3 | | 1994 | 1 | 2 | 3 | | 1995 | 2 | 6 | 8 | | 1996 | 3 | 1 | 4 | | 1997 | 3 | 8 | 11 | | 1998 | 1 | 6 | 7 | | 1999 | 4 | 1 | 5 | | 2000 | 2 | 1 | 3 | | 2001 | 8 | 3 | 11 | | 2002 | 5 | 4 | 9 | | 2003 | 7 | 2 | 9 | | 2004 | 3 | 0 | 3 | | 2005 | 3 | 4 | 7 | | 2006 | 4 | 5 | 9 | | 2007 | 7 | 6 | 13 | | 2008 | 1 | 4 | 5 | | 2009 | 5 | 2 | 7 | | 2010 | 1 | 5 | 6 | | 2011 | 2 | 2 | 4 | | 2012 | 2 | 0 | 2 | | 2013 | 3 | 1 | 4 | | 2014 | 1 | 4 | 5 | | 2015 | 2 | 3 | 5 | | 2016 | 2 | 1 | 3 | | 2017 | 2 | 0 | 2 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 2 | 3 | | 2021 | 0 | 3 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Thymus Gland" by people in Profiles.
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Kaiser C, Bradu A, Gamble N, Caldwell JA, Koh AS. AIRE in context: Leveraging chromatin plasticity to trigger ectopic gene expression. Immunol Rev. 2022 01; 305(1):59-76.
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Mallis RJ, Duke-Cohan JS, Das DK, Akitsu A, Luoma AM, Banik D, Stephens HM, Tetteh PW, Castro CD, Krahnke S, Hussey RE, Lawney B, Brazin KN, Reche PA, Hwang W, Adams EJ, Lang MJ, Reinherz EL. Molecular design of the ?dT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing. Proc Natl Acad Sci U S A. 2021 06 29; 118(26).
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Hammel JH, Cook SR, Belanger MC, Munson JM, Pompano RR. Modeling Immunity In Vitro: Slices, Chips, and Engineered Tissues. Annu Rev Biomed Eng. 2021 07 13; 23:461-491.
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Miller CH, Klawon DEJ, Zeng S, Lee V, Socci ND, Savage PA. Eomes identifies thymic precursors of self-specific memory-phenotype CD8+ T cells. Nat Immunol. 2020 05; 21(5):567-577.
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Chong AS. B cells as antigen-presenting cells in transplantation rejection and tolerance. Cell Immunol. 2020 03; 349:104061.
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Savage PA, Klawon DEJ, Miller CH. Regulatory T Cell Development. Annu Rev Immunol. 2020 04 26; 38:421-453.
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Waters D, Obeidin F, Alexiev BA, Rao MS, Peabody TD, Agulnik M, Yeldandi A. Ectopic hamartomatous thymoma in an immunocompromised male. Pathol Res Pract. 2019 Sep; 215(9):152497.
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Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, Henzler CM, Alegre ML, Anderson MS, August A, Marson A, Zheng Y, Williams CB, Farrar MA. Thymic regulatory T cells arise via two distinct developmental programs. Nat Immunol. 2019 02; 20(2):195-205.
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Ott JA, Castro CD, Deiss TC, Ohta Y, Flajnik MF, Criscitiello MF. Somatic hypermutation of T cell receptor a chain contributes to selection in nurse shark thymus. Elife. 2018 04 17; 7.
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Koh AS, Miller EL, Buenrostro JD, Moskowitz DM, Wang J, Greenleaf WJ, Chang HY, Crabtree GR. Rapid chromatin repression by Aire provides precise control of immune tolerance. Nat Immunol. 2018 02; 19(2):162-172.
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