Genetic Predisposition to Disease
"Genetic Predisposition to Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
| Descriptor ID |
D020022
|
| MeSH Number(s) |
C23.550.291.687.500 G05.380.355
|
| Concept/Terms |
Genetic Predisposition to Disease- Genetic Predisposition to Disease
- Genetic Susceptibility
- Genetic Susceptibilities
- Susceptibilities, Genetic
- Susceptibility, Genetic
- Genetic Predisposition
- Genetic Predispositions
- Predispositions, Genetic
- Predisposition, Genetic
|
Below are MeSH descriptors whose meaning is more general than "Genetic Predisposition to Disease".
Below are MeSH descriptors whose meaning is more specific than "Genetic Predisposition to Disease".
This graph shows the total number of publications written about "Genetic Predisposition to Disease" by people in this website by year, and whether "Genetic Predisposition to Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 2 | 3 | 5 |
| 1998 | 1 | 5 | 6 |
| 1999 | 4 | 5 | 9 |
| 2000 | 7 | 8 | 15 |
| 2001 | 9 | 13 | 22 |
| 2002 | 8 | 20 | 28 |
| 2003 | 10 | 20 | 30 |
| 2004 | 20 | 22 | 42 |
| 2005 | 21 | 27 | 48 |
| 2006 | 24 | 30 | 54 |
| 2007 | 25 | 36 | 61 |
| 2008 | 42 | 41 | 83 |
| 2009 | 26 | 29 | 55 |
| 2010 | 39 | 44 | 83 |
| 2011 | 35 | 53 | 88 |
| 2012 | 42 | 60 | 102 |
| 2013 | 26 | 35 | 61 |
| 2014 | 34 | 52 | 86 |
| 2015 | 21 | 47 | 68 |
| 2016 | 28 | 44 | 72 |
| 2017 | 31 | 57 | 88 |
| 2018 | 49 | 48 | 97 |
| 2019 | 39 | 52 | 91 |
| 2020 | 31 | 38 | 69 |
| 2021 | 25 | 55 | 80 |
| 2022 | 8 | 36 | 44 |
| 2023 | 5 | 28 | 33 |
| 2024 | 30 | 38 | 68 |
| 2025 | 19 | 34 | 53 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genetic Predisposition to Disease" by people in Profiles.
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Monogenic Type 1 Diabetes: A High Yield Pool in Which to Discover New Mechanisms and Candidate Therapeutics for Type 1 Diabetes. Cold Spring Harb Perspect Med. 2026 Feb 02; 16(2).
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Pathogenic Variants, Family History, and Cumulative Risk of Breast Cancer in US Women. JAMA Oncol. 2025 Dec 01; 11(12):1458-1469.
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Genetics of interstitial lung diseases: a state-of-the-art review. Eur Respir J. 2025 Sep; 66(3).
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Mutations of schizophrenia risk gene SETD1A dysregulate synaptic function in human neurons. Mol Psychiatry. 2025 Dec; 30(12):5680-5693.
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Availability of benign missense variant "truthsets" for validation of functional assays: Current status and a systematic approach. Am J Hum Genet. 2025 Oct 02; 112(10):2281-2294.
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Prediction and characterization of genetically regulated expression of asthma tissues from African-ancestry populations. J Allergy Clin Immunol. 2026 Jan; 157(1):253-261.
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Quantifying evidence for phenotypic specificity (PP4) for syndromic phenotypes: Large-scale integration of rare germline FH variants from diagnostic laboratory testing for HLRCC and renal cancer. Genet Med. 2025 Nov; 27(11):101565.
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PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia. Nature. 2025 Oct; 646(8087):1178-1186.
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The African-Specific Variant in the Duffy Antigen Receptor for Chemokines Gene, CD8+ T-Cell Density, and Aggressive Breast Cancer Subtypes in Black Women. Cancer Epidemiol Biomarkers Prev. 2025 Sep 02; 34(9):1509-1515.
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Polygenic risk score to define risk of cancer-associated thrombosis among patients with lung cancer in a population-based study. Lung Cancer. 2025 Sep; 207:108712.