CCAAT-Enhancer-Binding Protein-alpha
"CCAAT-Enhancer-Binding Protein-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CCAAT-enhancer-binding protein found in LIVER; ADIPOSE TISSUE; INTESTINES; LUNG; ADRENAL GLANDS; PLACENTA; OVARY and peripheral blood mononuclear cells (LEUKOCYTES, MONONUCLEAR). Experiments with knock-out mice have demonstrated that CCAAT-enhancer binding protein-alpha is essential for the functioning and differentiation of HEPATOCYTES and ADIPOCYTES.
| Descriptor ID |
D022763
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| MeSH Number(s) |
D12.776.260.108.124.500 D12.776.660.167.500 D12.776.930.127.124.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "CCAAT-Enhancer-Binding Protein-alpha".
Below are MeSH descriptors whose meaning is more specific than "CCAAT-Enhancer-Binding Protein-alpha".
This graph shows the total number of publications written about "CCAAT-Enhancer-Binding Protein-alpha" by people in this website by year, and whether "CCAAT-Enhancer-Binding Protein-alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "CCAAT-Enhancer-Binding Protein-alpha" by people in Profiles.
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C/EBPa expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBPa confers susceptibility to UVB-induced skin squamous cell carcinomas. J Invest Dermatol. 2011 Jun; 131(6):1339-46.
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A comparison of two methods for screening CEBPA mutations in patients with acute myeloid leukemia. J Mol Diagn. 2009 Jul; 11(4):319-23.
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Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nat Immunol. 2008 Feb; 9(2):203-15.
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Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice. Mol Cell Biol. 2006 Feb; 26(3):1109-23.
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The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of Calreticulin. Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13312-7.