 Symporters
"Symporters" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane transporters that co-transport two or more dissimilar molecules in the same direction across a membrane. Usually the transport of one ion or molecule is against its electrochemical gradient and is "powered" by the movement of another ion or molecule with its electrochemical gradient.
| Descriptor ID |
D027981
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| MeSH Number(s) |
D12.776.157.530.450.625 D12.776.543.585.450.625
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| Concept/Terms |
Symporters- Symporters
- Co-Transporters
- Co Transporters
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Below are MeSH descriptors whose meaning is more general than "Symporters".
Below are MeSH descriptors whose meaning is more specific than "Symporters".
This graph shows the total number of publications written about "Symporters" by people in this website by year, and whether "Symporters" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 1 | 0 | 1 | | 1987 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 2 | 0 | 2 | | 2004 | 2 | 0 | 2 | | 2005 | 1 | 1 | 2 | | 2006 | 0 | 3 | 3 | | 2007 | 0 | 3 | 3 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 4 | 4 | | 2010 | 2 | 2 | 4 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 6 | 6 | | 2014 | 0 | 3 | 3 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 | | 2017 | 0 | 5 | 5 | | 2018 | 1 | 1 | 2 | | 2019 | 3 | 1 | 4 | | 2020 | 2 | 2 | 4 | | 2021 | 2 | 0 | 2 | | 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Symporters" by people in Profiles.
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Liu H, Irobalieva RN, Bang-S?rensen R, Nosol K, Mukherjee S, Agrawal P, Stieger B, Kossiakoff AA, Locher KP. Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver. Cell Res. 2022 08; 32(8):773-776.
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Liao XH, Avalos P, Shelest O, Ofan R, Shilo M, Bresee C, Likhite S, Vit JP, Heuer H, Kaspar B, Meyer K, Dumitrescu AM, Refetoff S, Svendsen CN, Vatine GD. AAV9-MCT8 Delivery at Juvenile Stage Ameliorates Neurological and Behavioral Deficits in a Mouse Model of MCT8-Deficiency. Thyroid. 2022 07; 32(7):849-859.
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Iwayama H, Kakita H, Iwasa M, Adachi S, Takano K, Kikuchi M, Fujisawa Y, Osaka H, Yamada Y, Okumura A, Hirani K, Weiss RE, Refetoff S. Measurement of Reverse Triiodothyronine Level and the Triiodothyronine to Reverse Triiodothyronine Ratio in Dried Blood Spot Samples at Birth May Facilitate Early Detection of Monocarboxylate Transporter 8 Deficiency. Thyroid. 2021 09; 31(9):1316-1321.
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Cater RJ, Chua GL, Erramilli SK, Keener JE, Choy BC, Tokarz P, Chin CF, Quek DQY, Kloss B, Pepe JG, Parisi G, Wong BH, Clarke OB, Marty MT, Kossiakoff AA, Khelashvili G, Silver DL, Mancia F. Structural basis of omega-3 fatty acid transport across the blood-brain barrier. Nature. 2021 07; 595(7866):315-319.
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Refetoff S, Pappa T, Williams MK, Matheus MG, Liao XH, Hansen K, Nicol L, Pierce M, Blasco PA, Wiebers Jensen M, Bernal J, Weiss RE, Dumitrescu AM, LaFranchi S. Prenatal Treatment of Thyroid Hormone Cell Membrane Transport Defect Caused by MCT8 Gene Mutation. Thyroid. 2021 05; 31(5):713-720.
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Grijota-Mart?nez C, B?rez-L?pez S, Aus? E, Refetoff S, Frey WH, Guada?o-Ferraz A. Intranasal delivery of Thyroid hormones in MCT8 deficiency. PLoS One. 2020; 15(7):e0236113.
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Fu J, Korwutthikulrangsri M, Ramos-Platt L, Pierson TM, Liao XH, Refetoff S, Weiss RE, Dumitrescu AM. Sorting Variants of Unknown Significance Identified by Whole Exome Sequencing: Genetic and Laboratory Investigations of Two Novel MCT8 Variants. Thyroid. 2020 03; 30(3):463-465.
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Butler J, Handelsman Y, Bakris G, Verma S. Use of sodium-glucose co-transporter-2 inhibitors in patients with and without type 2 diabetes: implications for incident and prevalent heart failure. Eur J Heart Fail. 2020 04; 22(4):604-617.
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Tasdogan A, Faubert B, Ramesh V, Ubellacker JM, Shen B, Solmonson A, Murphy MM, Gu Z, Gu W, Martin M, Kasitinon SY, Vandergriff T, Mathews TP, Zhao Z, Schadendorf D, DeBerardinis RJ, Morrison SJ. Metabolic heterogeneity confers differences in melanoma metastatic potential. Nature. 2020 01; 577(7788):115-120.
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B?rez-L?pez S, Grijota-Mart?nez C, Liao XH, Refetoff S, Guada?o-Ferraz A. Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8. PLoS One. 2019; 14(12):e0226017.
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