"Glypicans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored, cell-surface heparan sulfate proteoglycans that may play a role in CELL GROWTH PROCESSES and CELL DIFFERENTIATION by modulating ligand-receptor interactions.
| Descriptor ID |
D053673
|
| MeSH Number(s) |
D12.776.395.550.448.500 D12.776.395.650.350.249 D12.776.543.484.500.550 D12.776.543.550.418.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Glypicans".
Below are MeSH descriptors whose meaning is more specific than "Glypicans".
This graph shows the total number of publications written about "Glypicans" by people in this website by year, and whether "Glypicans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glypicans" by people in Profiles.
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HCC EV ECG score: An extracellular vesicle-based protein assay for detection of early-stage hepatocellular carcinoma. Hepatology. 2023 03 01; 77(3):774-788.
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GPC5 rs2352028 polymorphism and risk of lung cancer in Han Chinese. Cancer Invest. 2012 Jan; 30(1):13-9.
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Common variation in GPC5 is associated with acquired nephrotic syndrome. Nat Genet. 2011 May; 43(5):459-63.
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Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development. Dev Biol. 2009 Nov 01; 335(1):208-15.
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Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans. Mol Cancer Ther. 2008 Sep; 7(9):3038-46.
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Mouse homologue of a novel human oncofetal antigen, glypican-3, evokes T-cell-mediated tumor rejection without autoimmune reactions in mice. Clin Cancer Res. 2004 Dec 15; 10(24):8630-40.
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Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker. Biochem Biophys Res Commun. 2003 Jun 20; 306(1):16-25.