"Syndecans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span transmembrane domain, and an extracellular domain with heparin sulfate and CHONDROITIN SULFATE chains. Syndecans interact with a variety of heparin-binding INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS and may play a role in modulating cellular signaling during EMBRYONIC DEVELOPMENT, tumorigenesis, and angiogenesis.
| Descriptor ID |
D053667
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| MeSH Number(s) |
D12.776.395.550.847 D12.776.395.650.350.500 D12.776.543.550.847
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Syndecans".
Below are MeSH descriptors whose meaning is more specific than "Syndecans".
This graph shows the total number of publications written about "Syndecans" by people in this website by year, and whether "Syndecans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Syndecans" by people in Profiles.
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Growth factors with enhanced syndecan binding generate tonic signalling and promote tissue healing. Nat Biomed Eng. 2020 04; 4(4):463-475.
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Molecular and cellular mechanisms of syndecans in tissue injury and inflammation. Mol Cells. 2007 Oct 31; 24(2):153-66.
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Expression of SHP-1 phosphatase indicates post-germinal center cell derivation of B-cell posttransplant lymphoproliferative disorders. Lab Invest. 2002 Nov; 82(11):1599-606.