G-Protein-Coupled Receptor Kinase 5
"G-Protein-Coupled Receptor Kinase 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A G-protein-coupled receptor kinase subtype that is primarily expressed in the MYOCARDIUM and may play a role in the regulation of cardiac functions.
| Descriptor ID |
D054774
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.364.775 D12.644.360.293.875 D12.776.476.293.875
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "G-Protein-Coupled Receptor Kinase 5".
Below are MeSH descriptors whose meaning is more specific than "G-Protein-Coupled Receptor Kinase 5".
This graph shows the total number of publications written about "G-Protein-Coupled Receptor Kinase 5" by people in this website by year, and whether "G-Protein-Coupled Receptor Kinase 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "G-Protein-Coupled Receptor Kinase 5" by people in Profiles.
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Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients. Pharmacogenet Genomics. 2011 Jan; 21(1):42-9.
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GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans. Pharmacogenomics. 2009 Oct; 10(10):1581-7.
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Myocardial function in hearts with transgenic overexpression of the G protein-coupled receptor kinase 5. Ann Thorac Surg. 2001 Apr; 71(4):1320-4.
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Myocardial overexpression of adrenergic receptors and receptor kinases. Adv Pharmacol. 1998; 42:502-6.
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Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice. Proc Natl Acad Sci U S A. 1996 Sep 03; 93(18):9954-9.