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RAYMOND P. ROOS

TitleProfessor
InstitutionUniversity of Chicago
DepartmentNeurology
AddressChicago IL 60637
Email
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    Collapse Overview 
    Collapse overview
    Dr Roos is the Marjorie and Robert E. Straus Professor in Neurological Science in the Department of Neurology. His research program is focused on the pathogenesis of neurodegenerative diseases, especially amyotrophic lateral sclerosis, and on investigations of picornavirus central nervous system infections. He has published more than 200 papers. Dr. Roos previously served as Chair of the Department of Neurology. He previously served on the Editorial Boards of the J. Neuroimmunology, J. Neurovirology, J. Virology, and Annals of Neurology, and presently serves on the Editorial Board of Virology and Scientific Reports. He is Associate Editor of Neurology Genetics and Editor-in-Chief of MedLink (an on-line Neurology site). He is a member of the US FDA Cellular, Tissues and Gene Therapies Advisory Committee. He formerly served as Chair of the FDA Transmissible Spongiform Encephalopathies Committee and Vaccines and Related Biological Products Advisory Committee. He was a member of the National Academy of Sciences Institute of Medicine Committee to Examine Multiple Sclerosis, American Academy of Neurology Science Committee, Amyotrophic Lateral Sclerosis (ALS) Association grant review committee, National Multiple Sclerosis Society Research Programs Advisory Committee (which he Chaired), and NIH NINDS grant review study section.


    Collapse Biography 
    Collapse education and training
    Columbia College, NYC, NYAB06/1964Chemistry, Premed
    SUNY, Downstate Medical Center, Brookly, NYC, NYmedicine06/1964Medicine
    Kings County Hospital, Brooklyn, NYC, NY06/1969Internship in Medicine
    NINDS, NIH, Bethesda, MD06/1971Slow Virus (prion) Laboratory of D.C. Gajdusek
    Johns Hopkins Hospital, Baltimore, MD06/1974Neurology Residency
    Johns Hopkins Hospital, Baltimore, MD06/1976Neurovirology and Neuroimmunology Post-doctoral fellowship
    University of Utah Medical Center, Salt Lake City, UT07/1981Visiting Professor in poliovirus lab of Dr. Ellie Ehrenfeld
    University of California, Irvine, Irvine, CA01/1989Visiting Professor in poliovirus lab of Dr. Bert Semler
    Collapse awards and honors
    2004Fellow in Medical Science, AAAS
    2006Society for Scholars, Johns Hopkins Medical School
    2018Dr. Frank L. Babbott, MD Memorial Award , SUNY Downstate

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ghadge GD, Kay BK, Drigotas C, Roos RP. Single chain variable fragment antibodies directed against SOD1 ameliorate disease in mutant SOD1 transgenic mice. Neurobiol Dis. 2019 Jan; 121:131-137. PMID: 30176351.
      View in: PubMed
    2. Sonobe Y, Ghadge G, Masaki K, Sendoel A, Fuchs E, Roos RP. Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress. Neurobiol Dis. 2018 Aug; 116:155-165. PMID: 29792928.
      View in: PubMed
    3. Riehm JJ, Wang L, Ghadge G, Teng M, Correa AM, Marks JD, Roos RP, Allen MJ. Poloxamer 188 decreases membrane toxicity of mutant SOD1 and ameliorates pathology observed in SOD1 mouse model for ALS. Neurobiol Dis. 2018 Jul; 115:115-126. PMID: 29627580.
      View in: PubMed
    4. Pulst SM, Johnson NE, Pandolfo M, Roos RP, Vance JM. 2017 Year in Review and Message from the Editors to Our Reviewers. Neurol Genet. 2018 Feb; 4(1):e221. PMID: 29552636.
      View in: PubMed
    5. Rezania K, Pytel P, Derani L, Greenwald R, Roos RP. A Masked Marauder: Hepatitis C Neuropathy. Am J Med. 2018 Jan; 131(1):33-36. PMID: 28882660.
      View in: PubMed
    6. Mackenzie IR, Nicholson AM, Sarkar M, Messing J, Purice MD, Pottier C, Annu K, Baker M, Perkerson RB, Kurti A, Matchett BJ, Mittag T, Temirov J, Hsiung GR, Krieger C, Murray ME, Kato M, Fryer JD, Petrucelli L, Zinman L, Weintraub S, Mesulam M, Keith J, Zivkovic SA, Hirsch-Reinshagen V, Roos RP, Züchner S, Graff-Radford NR, Petersen RC, Caselli RJ, Wszolek ZK, Finger E, Lippa C, Lacomis D, Stewart H, Dickson DW, Kim HJ, Rogaeva E, Bigio E, Boylan KB, Taylor JP, Rademakers R. TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics. Neuron. 2017 Aug 16; 95(4):808-816.e9. PMID: 28817800.
      View in: PubMed
    7. Jara JH, Genç B, Stanford MJ, Pytel P, Roos RP, Weintraub S, Mesulam MM, Bigio EH, Miller RJ, Özdinler PH. Evidence for an early innate immune response in the motor cortex of ALS. J Neuroinflammation. 2017 Jun 26; 14(1):129. PMID: 28651542.
      View in: PubMed
    8. Pulst SM, Johnson NE, Durr A, Pandolfo M, Roos RP, Vance JM. 2016 in Review and Message from the Editors to our Reviewers. Neurol Genet. 2017 Feb; 3(1):e132. PMID: 28251178.
      View in: PubMed
    9. Genç B, Jara JH, Lagrimas AK, Pytel P, Roos RP, Mesulam MM, Geula C, Bigio EH, Özdinler PH. Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS. Sci Rep. 2017 Feb 06; 7:41765. PMID: 28165465.
      View in: PubMed
    10. Issa NP, Frank S, Roos RP, Soliven B, Towle VL, Rezania K. Intermuscular coherence in amyotrophic lateral sclerosis: A preliminary assessment. Muscle Nerve. 2017 Jun; 55(6):862-868. PMID: 27699797.
      View in: PubMed
    11. Antinone SE, Ghadge GD, Ostrow LW, Roos RP, Green WN. S-acylation of SOD1, CCS, and a stable SOD1-CCS heterodimer in human spinal cords from ALS and non-ALS subjects. Sci Rep. 2017 Jan 25; 7:41141. PMID: 28120938.
      View in: PubMed
    12. Roos RP. Zika Virus-A Public Health Emergency of International Concern. JAMA Neurol. 2016 Dec 01; 73(12):1395-1396. PMID: 27695847.
      View in: PubMed
    13. Kak M, Issa NP, Roos RP, Sweitzer BJ, Gottlieb O, Guralnick A, White SR, Semrad CE, Soliven B, Baroody J, Rezania K. Gastrostomy tube placement is safe in advanced amyotrophic lateral sclerosis. Neurol Res. 2017 Jan; 39(1):16-22. PMID: 27876446.
      View in: PubMed
    14. Labuschagne I, Cassidy AM, Scahill RI, Johnson EB, Rees E, O'Regan A, Queller S, Frost C, Leavitt BR, Dürr A, Roos R, Owen G, Borowsky B, Tabrizi SJ, Stout JC. Visuospatial Processing Deficits Linked to Posterior Brain Regions in Premanifest and Early Stage Huntington's Disease. J Int Neuropsychol Soc. 2016 Jul; 22(6):595-608. PMID: 27211109.
      View in: PubMed
    15. Beversdorf DQ, Lennon V, Mehler M, Roos R. Author Response. Neurology. 2016 Feb 09; 86(6):585-6. PMID: 27280229.
      View in: PubMed
    16. Bennett SJ, Katzman GL, Roos RP, Mehta AS, Ali S. Neoplastic cauda equina syndrome: a neuroimaging-based review. Pract Neurol. 2016 Feb; 16(1):35-41. PMID: 26442520.
      View in: PubMed
    17. Beversdorf DQ, Roos RP, Hauser WA, Lennon VA, Mehler MF. Animal extremists' threats to neurologic research continue: Neuroreality II. Neurology. 2015 Aug 25; 85(8):730-4. PMID: 26156507.
      View in: PubMed
    18. Visscher AP, Schuur D, Roos R, Van der Mijnsbrugge GJ, Meijerink WJ, Felt-Bersma RJ. Long-term follow-up after surgery for simple and complex cryptoglandular fistulas: fecal incontinence and impact on quality of life. Dis Colon Rectum. 2015 May; 58(5):533-9. PMID: 25850841.
      View in: PubMed
    19. Roos RP. D. CARLETON GAJDUSEK. Proc Am Philos Soc. 2015 Mar; 159(1):97-106. PMID: 27011963.
      View in: PubMed
    20. Jara JH, Genç B, Cox GA, Bohn MC, Roos RP, Macklis JD, Ulupinar E, Özdinler PH. Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function. Cereb Cortex. 2015 Nov; 25(11):4259-72. PMID: 25596590.
      View in: PubMed
    21. Rezania K, Gottlieb O, Guralnick A, Prachand V, Sweitzer BJ, Vigneswaran W, White SR, Roos RP. Venous thromboembolism after diaphragm pacing in amyotrophic lateral sclerosis. Muscle Nerve. 2014 Nov; 50(5):863-5. PMID: 25111569.
      View in: PubMed
    22. Wang L, Popko B, Tixier E, Roos RP. Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis. Neurobiol Dis. 2014 Nov; 71:317-24. PMID: 25134731.
      View in: PubMed
    23. Wang L, Popko B, Roos RP. An enhanced integrated stress response ameliorates mutant SOD1-induced ALS. Hum Mol Genet. 2014 May 15; 23(10):2629-38. PMID: 24368417.
      View in: PubMed
    24. Antinone SE, Ghadge GD, Lam TT, Wang L, Roos RP, Green WN. Palmitoylation of superoxide dismutase 1 (SOD1) is increased for familial amyotrophic lateral sclerosis-linked SOD1 mutants. J Biol Chem. 2013 Jul 26; 288(30):21606-17. PMID: 23760509.
      View in: PubMed
    25. Ghadge GD, Pavlovic JD, Koduvayur SP, Kay BK, Roos RP. Single chain variable fragment antibodies block aggregation and toxicity induced by familial ALS-linked mutant forms of SOD1. Neurobiol Dis. 2013 Aug; 56:74-8. PMID: 23607939.
      View in: PubMed
    26. Rezania K, Roos RP. Spinal cord: motor neuron diseases. Neurol Clin. 2013 Feb; 31(1):219-39. PMID: 23186902.
      View in: PubMed
    27. Wang L, Pytel P, Feltri ML, Wrabetz L, Roos RP. Selective knockdown of mutant SOD1 in Schwann cells ameliorates disease in G85R mutant SOD1 transgenic mice. Neurobiol Dis. 2012 Oct; 48(1):52-7. PMID: 22668777.
      View in: PubMed
    28. Allen MJ, Lacroix JJ, Ramachandran S, Capone R, Whitlock JL, Ghadge GD, Arnsdorf MF, Roos RP, Lal R. Mutant SOD1 forms ion channel: implications for ALS pathophysiology. Neurobiol Dis. 2012 Mar; 45(3):831-8. PMID: 21930207.
      View in: PubMed
    29. Ghadge GD, Wollmann R, Baida G, Traka M, Roos RP. The L-coding region of the DA strain of Theiler's murine encephalomyelitis virus causes dysfunction and death of myelin-synthesizing cells. J Virol. 2011 Sep; 85(18):9377-84. PMID: 21752920.
      View in: PubMed
    30. Stavrou S, Ghadge G, Roos RP. Apoptotic and antiapoptotic activity of L protein of Theiler's murine encephalomyelitis virus. J Virol. 2011 Jul; 85(14):7177-85. PMID: 21561911.
      View in: PubMed
    31. Rezania K, Soliven B, Rezai KA, Roos RP. Impaired glucose tolerance and metabolic syndrome in idiopathic polyneuropathy: the role of pain and depression. Med Hypotheses. 2011 Apr; 76(4):538-42. PMID: 21255940.
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    32. Wang L, Popko B, Roos RP. The unfolded protein response in familial amyotrophic lateral sclerosis. Hum Mol Genet. 2011 Mar 01; 20(5):1008-15. PMID: 21159797.
      View in: PubMed
    33. Wang L, Gutmann DH, Roos RP. Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice. Hum Mol Genet. 2011 Jan 15; 20(2):286-93. PMID: 20962037.
      View in: PubMed
    34. Stavrou S, Feng Z, Lemon SM, Roos RP. Different strains of Theiler's murine encephalomyelitis virus antagonize different sites in the type I interferon pathway. J Virol. 2010 Sep; 84(18):9181-9. PMID: 20610716.
      View in: PubMed
    35. Wang L, Grisotti G, Roos RP. Mutant SOD1 knockdown in all cell types ameliorates disease in G85R SOD1 mice with a limited additional effect over knockdown restricted to motor neurons. J Neurochem. 2010 Apr; 113(1):166-74. PMID: 20132483.
      View in: PubMed
    36. Stavrou S, Baida G, Viktorova E, Ghadge G, Agol VI, Roos RP. Theiler's murine encephalomyelitis virus L* amino acid position 93 is important for virus persistence and virus-induced demyelination. J Virol. 2010 Feb; 84(3):1348-54. PMID: 19923182.
      View in: PubMed
    37. Thomas AG, Bodner A, Ghadge G, Roos RP, Slusher BS. GCP II inhibition rescues neurons from gp120IIIB-induced neurotoxicity. J Neurovirol. 2009 Sep; 15(5-6):449-57. PMID: 19995130.
      View in: PubMed
    38. Wang L, Sharma K, Grisotti G, Roos RP. The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis. Neurobiol Dis. 2009 Aug; 35(2):234-40. PMID: 19442735.
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    39. Wang L, Deng HX, Grisotti G, Zhai H, Siddique T, Roos RP. Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse. Hum Mol Genet. 2009 May 01; 18(9):1642-51. PMID: 19233858.
      View in: PubMed
    40. Roos RP, Soliven B, Goldenberg F, Badruddin A, Baron JM. An elderly patient with Bickerstaff brainstem encephalitis and transient episodes of brainstem dysfunction. Arch Neurol. 2008 Jun; 65(6):821-4. PMID: 18541805.
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    41. Baida G, Popko B, Wollmann RL, Stavrou S, Lin W, Tretiakova M, Krausz TN, Roos RP. A subgenomic segment of Theiler's murine encephalomyelitis virus RNA causes demyelination. J Virol. 2008 Jun; 82(12):5879-86. PMID: 18400855.
      View in: PubMed
    42. Wang L, Sharma K, Deng HX, Siddique T, Grisotti G, Liu E, Roos RP. Restricted expression of mutant SOD1 in spinal motor neurons and interneurons induces motor neuron pathology. Neurobiol Dis. 2008 Mar; 29(3):400-8. PMID: 18054242.
      View in: PubMed
    43. Ghadge GD, Wang L, Sharma K, Monti AL, Bindokas V, Stevens FJ, Roos RP. Truncated wild-type SOD1 and FALS-linked mutant SOD1 cause neural cell death in the chick embryo spinal cord. Neurobiol Dis. 2006 Jan; 21(1):194-205. PMID: 16084730.
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    44. Guest S, Pilipenko E, Sharma K, Chumakov K, Roos RP. Molecular mechanisms of attenuation of the Sabin strain of poliovirus type 3. J Virol. 2004 Oct; 78(20):11097-107. PMID: 15452230.
      View in: PubMed
    45. Lin X, Ma X, Rodriguez M, Roos RP. CD4+ T cells are important for clearance of DA strain of TMEV from the central nervous system of SJL/J mice. Int Immunol. 2004 Sep; 16(9):1237-40. PMID: 15262897.
      View in: PubMed
    46. Nix WA, Berger MM, Oberste MS, Brooks BR, McKenna-Yasek DM, Brown RH, Roos RP, Pallansch MA. Failure to detect enterovirus in the spinal cord of ALS patients using a sensitive RT-PCR method. Neurology. 2004 Apr 27; 62(8):1372-7. PMID: 15111676.
      View in: PubMed
    47. Mathiasen JR, McKenna BA, Saporito MS, Ghadge GD, Roos RP, Holskin BP, Wu ZL, Trusko SP, Connors TC, Maroney AC, Thomas BA, Thomas JC, Bozyczko-Coyne D. Inhibition of mixed lineage kinase 3 attenuates MPP+-induced neurotoxicity in SH-SY5Y cells. Brain Res. 2004 Apr 02; 1003(1-2):86-97. PMID: 15019567.
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    48. Mastrianni JA, Roos RP. Wrinkles and folds of the prion protein. Neurology. 2003 Nov 11; 61(9):1168-9. PMID: 14610113.
      View in: PubMed
    49. Rezania K, Yan J, Dellefave L, Deng HX, Siddique N, Pascuzzi RT, Siddique T, Roos RP. A rare Cu/Zn superoxide dismutase mutation causing familial amyotrophic lateral sclerosis with variable age of onset, incomplete penetrance and a sensory neuropathy. Amyotroph Lateral Scler Other Motor Neuron Disord. 2003 Sep; 4(3):162-6. PMID: 13129803.
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    50. Lin X, Ma X, Rodriguez M, Feng X, Zoecklein L, Fu YX, Roos RP. Membrane lymphotoxin is required for resistance to Theiler's virus infection. Int Immunol. 2003 Aug; 15(8):955-62. PMID: 12882833.
      View in: PubMed
    51. Ghadge GD, Slusher BS, Bodner A, Canto MD, Wozniak K, Thomas AG, Rojas C, Tsukamoto T, Majer P, Miller RJ, Monti AL, Roos RP. Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models. Proc Natl Acad Sci U S A. 2003 Aug 05; 100(16):9554-9. PMID: 12876198.
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    52. Bodner A, Maroney AC, Finn JP, Ghadge G, Roos R, Miller RJ. Mixed lineage kinase 3 mediates gp120IIIB-induced neurotoxicity. J Neurochem. 2002 Sep; 82(6):1424-34. PMID: 12354290.
      View in: PubMed
    53. Lee JP, Gerin C, Bindokas VP, Miller R, Ghadge G, Roos RP. No correlation between aggregates of Cu/Zn superoxide dismutase and cell death in familial amyotrophic lateral sclerosis. J Neurochem. 2002 Sep; 82(5):1229-38. PMID: 12358770.
      View in: PubMed
    54. Mastrianni J, Roos RP. "Out, damned spot! out, I say!...": issues related to prion decontamination. Neurology. 2002 Aug 27; 59(4):488-9. PMID: 12196639.
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    55. Maat-Kievit A, Helderman-van den Enden P, Losekoot M, de Knijff P, Belfroid R, Vegter-van der Vlis M, Roos R, Breuning M. Using a roster and haplotyping is useful in risk assessment for persons with intermediate and reduced penetrance alleles in Huntington disease. Am J Med Genet. 2001 Dec 08; 105(8):737-44. PMID: 11803522.
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    56. Pilipenko EV, Viktorova EG, Guest ST, Agol VI, Roos RP. Cell-specific proteins regulate viral RNA translation and virus-induced disease. EMBO J. 2001 Dec 03; 20(23):6899-908. PMID: 11726525.
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    57. Roos RP. Controlling new prion diseases. N Engl J Med. 2001 May 17; 344(20):1548-51. PMID: 11357162.
      View in: PubMed
    58. Hentati A, Deng HX, Zhai H, Chen W, Yang Y, Hung WY, Azim AC, Bohlega S, Tandan R, Warner C, Laing NG, Cambi F, Mitsumoto H, Roos RP, Boustany RM, Ben Hamida M, Hentati F, Siddique T. Novel mutations in spastin gene and absence of correlation with age at onset of symptoms. Neurology. 2000 Nov 14; 55(9):1388-90. PMID: 11087788.
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    59. Lüders JC, Weihl CC, Lin G, Ghadge G, Stoodley M, Roos RP, Macdonald RL. Adenoviral gene transfer of nitric oxide synthase increases cerebral blood flow in rats. Neurosurgery. 2000 Nov; 47(5):1206-14; discussion 1214-5. PMID: 11063115.
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    60. Rodriguez M, Roos RP, McGavern D, Zoecklein L, Pavelko K, Sang H, Lin X. The CD4-mediated immune response is critical in determining the outcome of infection using Theiler's viruses with VP1 capsid protein point mutations. Virology. 2000 Sep 15; 275(1):9-19. PMID: 11017783.
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    61. Stoodley M, Weihl CC, Zhang ZD, Lin G, Johns LM, Kowalczuk A, Ghadge G, Roos RP, Macdonald RL. Effect of adenovirus-mediated nitric oxide synthase gene transfer on vasospasm after experimental subarachnoid hemorrhage. Neurosurgery. 2000 May; 46(5):1193-202; discussion 1202-3. PMID: 10807252.
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    62. Miller RJ, Roos RP. What happens when mutant neuroserpins get into bad shape. Lancet. 2000 Feb 19; 355(9204):590-1. PMID: 10696974.
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    63. Mastrianni JA, Roos RP. The prion diseases. Semin Neurol. 2000; 20(3):337-52. PMID: 11051298.
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    64. Weihl CC, Roos RP. Creutzfeldt-Jakob disease, new variant creutzfeldt-jakob disease, and bovine spongiform encephalopathy. Neurol Clin. 1999 Nov; 17(4):835-59. PMID: 10517931.
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    65. Yamasaki K, Weihl CC, Roos RP. Alternative translation initiation of Theiler's murine encephalomyelitis virus. J Virol. 1999 Oct; 73(10):8519-26. PMID: 10482605.
      View in: PubMed
    66. Weihl CC, Miller RJ, Roos RP. The role of beta-catenin stability in mutant PS1-associated apoptosis. Neuroreport. 1999 Aug 20; 10(12):2527-32. PMID: 10574364.
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    67. Weihl CC, Ghadge GD, Miller RJ, Roos RP. Processing of wild-type and mutant familial Alzheimer's disease-associated presenilin-1 in cultured neurons. J Neurochem. 1999 Jul; 73(1):31-40. PMID: 10386952.
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    68. Weihl CC, Ghadge GD, Kennedy SG, Hay N, Miller RJ, Roos RP. Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB. J Neurosci. 1999 Jul 01; 19(13):5360-9. PMID: 10377346.
      View in: PubMed
    69. Lee JP, Palfrey HC, Bindokas VP, Ghadge GD, Ma L, Miller RJ, Roos RP. The role of immunophilins in mutant superoxide dismutase-1linked familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):3251-6. PMID: 10077670.
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    70. Lin X, Roos RP, Pease LR, Wettstein P, Rodriguez M. A Theiler's virus alternatively initiated protein inhibits the generation of H-2K-restricted virus-specific cytotoxicity. J Immunol. 1999 Jan 01; 162(1):17-24. PMID: 9886365.
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    71. Ghadge GD, Ma L, Sato S, Kim J, Roos RP. A protein critical for a Theiler's virus-induced immune system-mediated demyelinating disease has a cell type-specific antiapoptotic effect and a key role in virus persistence. J Virol. 1998 Nov; 72(11):8605-12. PMID: 9765399.
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    72. Takata H, Obuchi M, Yamamoto J, Odagiri T, Roos RP, Iizuka H, Ohara Y. L* protein of the DA strain of Theiler's murine encephalomyelitis virus is important for virus growth in a murine macrophage-like cell line. J Virol. 1998 Jun; 72(6):4950-5. PMID: 9573263.
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    73. Lin X, Sato S, Patick AK, Pease LR, Roos RP, Rodriguez M. Molecular characterization of a nondemyelinating variant of Daniel's strain of Theiler's virus isolated from a persistently infected glioma cell line. J Virol. 1998 Feb; 72(2):1262-9. PMID: 9445026.
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    74. Ghadge GD, Lee JP, Bindokas VP, Jordan J, Ma L, Miller RJ, Roos RP. Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection. J Neurosci. 1997 Nov 15; 17(22):8756-66. PMID: 9348345.
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    75. Sato S, Reiner SL, Jensen MA, Roos RP. Central nervous system cytokine mRNA expression following Theiler's murine encephalomyelitis virus infection. J Neuroimmunol. 1997 Jun; 76(1-2):213-23. PMID: 9184653.
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    76. Roos RP. The regulation of gene expression in neurotrophic viruses. J Neurovirol. 1997 May; 3 Suppl 1:S25-7. PMID: 9179786.
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    77. Rinehart JE, Gómez RM, Roos RP. Molecular determinants for virulence in coxsackievirus B1 infection. J Virol. 1997 May; 71(5):3986-91. PMID: 9094675.
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    78. Prehn JH, Jordán J, Ghadge GD, Preis E, Galindo MF, Roos RP, Krieglstein J, Miller RJ. Ca2+ and reactive oxygen species in staurosporine-induced neuronal apoptosis. J Neurochem. 1997 Apr; 68(4):1679-85. PMID: 9084441.
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    79. Jordán J, Galindo MF, Prehn JH, Weichselbaum RR, Beckett M, Ghadge GD, Roos RP, Leiden JM, Miller RJ. p53 expression induces apoptosis in hippocampal pyramidal neuron cultures. J Neurosci. 1997 Feb 15; 17(4):1397-405. PMID: 9006981.
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    80. Sato S, Zhang L, Kim J, Jakob J, Grant RA, Wollmann R, Roos RP. A neutralization site of DA strain of Theiler's murine encephalomyelitis virus important for disease phenotype. Virology. 1996 Dec 15; 226(2):327-37. PMID: 8955052.
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    81. Piccone ME, Chen HH, Roos RP, Grubman MJ. Construction of a chimeric Theiler's murine encephalomyelitis virus containing the leader gene of foot-and-mouth disease virus. Virology. 1996 Dec 01; 226(1):135-9. PMID: 8941332.
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    82. Gómez RM, Rinehart JE, Wollmann R, Roos RP. Theiler's murine encephalomyelitis virus-induced cardiac and skeletal muscle disease. J Virol. 1996 Dec; 70(12):8926-33. PMID: 8971022.
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    83. Hackett J, Swanson P, Leahy D, Anderson EL, Sato S, Roos RP, Decker R, Devare SG. Search for retrovirus in patients with multiple sclerosis. Ann Neurol. 1996 Nov; 40(5):805-9. PMID: 8957025.
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    84. Moss AH, Oppenheimer EA, Casey P, Cazzolli PA, Roos RP, Stocking CB, Siegler M. Patients with amyotrophic lateral sclerosis receiving long-term mechanical ventilation. Advance care planning and outcomes. Chest. 1996 Jul; 110(1):249-55. PMID: 8681635.
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    85. Furlan R, Salazar-Grueso EF, Martino G, Roos RP, Brambilla E, Castellano M, Cao J, Lillo F, Terreni MR, Bacellar H, Dorigatti F, Grimaldi LM. Human T-cell lymphotropic virus type-I infection in the severe combined immunodeficiency mouse. J Med Virol. 1996 Jun; 49(2):77-82. PMID: 8991939.
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    86. Jakob J, Roos RP. Molecular determinants of Theiler's murine encephalomyelitis-induced disease. J Neurovirol. 1996 Apr; 2(2):70-7. PMID: 8799198.
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    87. Prehn JH, Bindokas VP, Jordán J, Galindo MF, Ghadge GD, Roos RP, Boise LH, Thompson CB, Krajewski S, Reed JC, Miller RJ. Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons. Mol Pharmacol. 1996 Feb; 49(2):319-28. PMID: 8632765.
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    88. Chen HH, Kong WP, Roos RP. The leader peptide of Theiler's murine encephalomyelitis virus is a zinc-binding protein. J Virol. 1995 Dec; 69(12):8076-8. PMID: 7494325.
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    89. Chen HH, Kong WP, Zhang L, Ward PL, Roos RP. A picornaviral protein synthesized out of frame with the polyprotein plays a key role in a virus-induced immune-mediated demyelinating disease. Nat Med. 1995 Sep; 1(9):927-31. PMID: 7585219.
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    90. Tateishi J, Brown P, Kitamoto T, Hoque ZM, Roos R, Wollman R, Cervenáková L, Gajdusek DC. First experimental transmission of fatal familial insomnia. Nature. 1995 Aug 03; 376(6539):434-5. PMID: 7630420.
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    91. Brown P, Kenney K, Little B, Ironside J, Will R, Cervenáková L, Bjork RJ, San Martin RA, Safar J, Roos R, et al. Intracerebral distribution of infectious amyloid protein in spongiform encephalopathy. Ann Neurol. 1995 Aug; 38(2):245-53. PMID: 7654073.
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    92. Jordan J, Ghadge GD, Prehn JH, Toth PT, Roos RP, Miller RJ. Expression of human copper/zinc-superoxide dismutase inhibits the death of rat sympathetic neurons caused by withdrawal of nerve growth factor. Mol Pharmacol. 1995 Jun; 47(6):1095-1100. PMID: 7603446.
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    93. Maselli RA, Wollmann R, Roos R. Function and ultrastructure of the neuromuscular junction in post-polio syndrome. Ann N Y Acad Sci. 1995 May 25; 753:129-37. PMID: 7611622.
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    94. Jubelt B, Salazar-Grueso EF, Roos RP, Cashman NR. Antibody titer to the poliovirus in blood and cerebrospinal fluid of patients with post-polio syndrome. Ann N Y Acad Sci. 1995 May 25; 753:201-7. PMID: 7611629.
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    95. Chard PS, Jordán J, Marcuccilli CJ, Miller RJ, Leiden JM, Roos RP, Ghadge GD. Regulation of excitatory transmission at hippocampal synapses by calbindin D28k. Proc Natl Acad Sci U S A. 1995 May 23; 92(11):5144-8. PMID: 7761464.
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    96. Zhang L, Sato S, Kim JI, Roos RP. Theiler's virus as a vector for foreign gene delivery. J Virol. 1995 May; 69(5):3171-5. PMID: 7707546.
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    97. Ghadge GD, Roos RP, Kang UJ, Wollmann R, Fishman PS, Kalynych AM, Barr E, Leiden JM. CNS gene delivery by retrograde transport of recombinant replication-defective adenoviruses. Gene Ther. 1995 Mar; 2(2):132-7. PMID: 7536617.
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    98. Senkowski A, Shim B, Roos RP. The effect of Theiler's murine encephalomyelitis virus (TMEV) VP1 carboxyl region on the virus-induced central nervous system disease. J Neurovirol. 1995 Mar; 1(1):101-10. PMID: 9222346.
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    99. Salazar-Grueso EF, Roos RP. Amyotrophic lateral sclerosis and viruses. Clin Neurosci. 1995-1996; 3(6):360-7. PMID: 9021257.
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    100. Furlan R, Salazar-Grueso EF, Martino G, Lillo F, Kotulski M, Brambilla E, Castellano M, Terreni MR, Roos RP, Grimaldi LM. HTLV-I hu-SCID mouse in the study of HTLV-I neurotropism. Ann N Y Acad Sci. 1994 Jun 06; 724:422-5. PMID: 8030969.
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    101. Jarousse N, Grant RA, Hogle JM, Zhang L, Senkowski A, Roos RP, Michiels T, Brahic M, McAllister A. A single amino acid change determines persistence of a chimeric Theiler's virus. J Virol. 1994 May; 68(5):3364-8. PMID: 7512164.
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    102. Kong WP, Ghadge GD, Roos RP. Involvement of cardiovirus leader in host cell-restricted virus expression. Proc Natl Acad Sci U S A. 1994 Mar 01; 91(5):1796-800. PMID: 8127884.
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    103. Appelbaum JS, Roos RP. Coexistence of amyotrophic lateral sclerosis and Werdnig-Hoffmann disease within a family. Muscle Nerve. 1993 Dec; 16(12):1416. PMID: 8232401.
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    104. Maselli RA, Wollman RL, Leung C, Distad B, Palombi S, Richman DP, Salazar-Grueso EF, Roos RP. Neuromuscular transmission in amyotrophic lateral sclerosis. Muscle Nerve. 1993 Nov; 16(11):1193-203. PMID: 8105377.
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    105. Deng HX, Hentati A, Tainer JA, Iqbal Z, Cayabyab A, Hung WY, Getzoff ED, Hu P, Herzfeldt B, Roos RP, et al. Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase. Science. 1993 Aug 20; 261(5124):1047-51. PMID: 8351519.
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    106. Zhang L, Senkowski A, Shim B, Roos RP. Chimeric cDNA studies of Theiler's murine encephalomyelitis virus neurovirulence. J Virol. 1993 Jul; 67(7):4404-8. PMID: 8510228.
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    107. Moss AH, Casey P, Stocking CB, Roos RP, Brooks BR, Siegler M. Home ventilation for amyotrophic lateral sclerosis patients: outcomes, costs, and patient, family, and physician attitudes. Neurology. 1993 Feb; 43(2):438-43. PMID: 8437718.
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    108. Rubeiz H, Roos RP. Viral meningitis and encephalitis. Semin Neurol. 1992 Sep; 12(3):165-77. PMID: 1455104.
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    109. Appelbaum JS, Roos RP, Salazar-Grueso EF, Buchman A, Iannaccone S, Glantz R, Siddique T, Maselli R. Intrafamilial heterogeneity in hereditary motor neuron disease. Neurology. 1992 Aug; 42(8):1488-92. PMID: 1641141.
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    110. Stein SB, Zhang L, Roos RP. Influence of Theiler's murine encephalomyelitis virus 5' untranslated region on translation and neurovirulence. J Virol. 1992 Jul; 66(7):4508-17. PMID: 1602556.
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    111. Maselli RA, Cashman NR, Wollman RL, Salazar-Grueso EF, Roos R. Neuromuscular transmission as a function of motor unit size in patients with prior poliomyelitis. Muscle Nerve. 1992 Jun; 15(6):648-55. PMID: 1324424.
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    112. Salazar-Grueso EF, Roos RP, Jubelt B, Cashman NR. Immune responses in the post-polio syndrome. N Engl J Med. 1992 Feb 27; 326(9):641; author reply 642. PMID: 1370858.
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    113. Rodriguez M, Roos RP. Pathogenesis of early and late disease in mice infected with Theiler's virus, using intratypic recombinant GDVII/DA viruses. J Virol. 1992 Jan; 66(1):217-25. PMID: 1727485.
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    114. Silverstein MD, Stocking CB, Antel JP, Beckwith J, Roos RP, Siegler M. Amyotrophic lateral sclerosis and life-sustaining therapy: patients' desires for information, participation in decision making, and life-sustaining therapy. Mayo Clin Proc. 1991 Sep; 66(9):906-13. PMID: 1921500.
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    115. Kong WP, Roos RP. Alternative translation initiation site in the DA strain of Theiler's murine encephalomyelitis virus. J Virol. 1991 Jun; 65(6):3395-9. PMID: 2033677.
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    116. Grimaldi LM, Castagna A, Maimone D, Martino GV, Dolci A, Pristera R, Lazzarin A, Roos RP. Kappa light chain predominance in serum and cerebrospinal fluid from human immunodeficiency virus type 1 (HIV-1)-infected patients. J Neuroimmunol. 1991 Jun; 32(3):259-68. PMID: 1903402.
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    117. Zurbriggen A, Thomas C, Yamada M, Roos RP, Fujinami RS. Direct evidence of a role for amino acid 101 of VP-1 in central nervous system disease in Theiler's murine encephalomyelitis virus infection. J Virol. 1991 Apr; 65(4):1929-37. PMID: 1705992.
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    118. Kremer B, Swaab D, Bots G, Fisser B, Ravid R, Roos R. The hypothalamic lateral tuberal nucleus in Alzheimer's disease. Ann Neurol. 1991 Mar; 29(3):279-84. PMID: 1710433.
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    119. Fu J, Rodriguez M, Roos RP. Strains from both Theiler's virus subgroups encode a determinant for demyelination. J Virol. 1990 Dec; 64(12):6345-8. PMID: 2243399.
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    120. Salazar-Grueso EF, Holzer TJ, Gutierrez RA, Casey JM, Desai SM, Devare SG, Dawson G, Roos RP. Familial spastic paraparesis syndrome associated with HTLV-I infection. N Engl J Med. 1990 Sep 13; 323(11):732-7. PMID: 2388670.
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    121. Fu JL, Stein S, Rosenstein L, Bodwell T, Routbort M, Semler BL, Roos RP. Neurovirulence determinants of genetically engineered Theiler viruses. Proc Natl Acad Sci U S A. 1990 Jun; 87(11):4125-9. PMID: 2161533.
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    122. Salazar-Grueso EF, Routbort MJ, Martin J, Dawson G, Roos RP. Polyclonal IgM anti-GM1 ganglioside antibody in patients with motor neuron disease and variants. Ann Neurol. 1990 May; 27(5):558-63. PMID: 2113790.
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    123. Salazar-Grueso EF, Siegel I, Roos RP. The post-polio syndrome: evaluation and treatment. Compr Ther. 1990 Feb; 16(2):24-30. PMID: 2178859.
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    124. Salazar-Grueso EF, Grimaldi LM, Roos RP, Variakojis R, Jubelt B, Cashman NR. Isoelectric focusing studies of serum and cerebrospinal fluid in patients with antecedent poliomyelitis. Ann Neurol. 1989 Dec; 26(6):709-13. PMID: 2513770.
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    125. Roos RP, Kong WP, Semler BL. Polyprotein processing of Theiler's murine encephalomyelitis virus. J Virol. 1989 Dec; 63(12):5344-53. PMID: 2555559.
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    126. Roos RP, Stein S, Ohara Y, Fu JL, Semler BL. Infectious cDNA clones of the DA strain of Theiler's murine encephalomyelitis virus. J Virol. 1989 Dec; 63(12):5492-6. PMID: 2555569.
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    127. Roos RP, Stein S, Routbort M, Senkowski A, Bodwell T, Wollmann R. Theiler's murine encephalomyelitis virus neutralization escape mutants have a change in disease phenotype. J Virol. 1989 Oct; 63(10):4469-73. PMID: 2476574.
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    128. Siddique T, Pericak-Vance MA, Brooks BR, Roos RP, Hung WY, Antel JP, Munsat TL, Phillips K, Warner K, Speer M, et al. Linkage analysis in familial amyotrophic lateral sclerosis. Neurology. 1989 Jul; 39(7):919-25. PMID: 2739919.
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    129. Ohara Y, Roos RP. Viral infectious complementary-DNA studies may identify nonviral genes critical to central nervous system disease. Ann Neurol. 1989 Mar; 25(3):305-9. PMID: 2543264.
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    130. Grimaldi LM, Roos RP, Devare SG, Casey JM, Maruo Y, Hamada T, Tashiro K. HTLV-I-associated myelopathy: oligoclonal immunoglobulin G bands contain anti-HTLV-I p24 antibody. Ann Neurol. 1988 Dec; 24(6):727-31. PMID: 3207356.
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    131. Ohara Y, Senkowski A, Fu JL, Klaman L, Goodall J, Toth M, Roos RP. Trypsin-sensitive neutralization site on VP1 of Theiler's murine encephalomyelitis viruses. J Virol. 1988 Sep; 62(9):3527-9. PMID: 2457118.
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    132. Grimaldi LM, Roos RP, Manservigi R, Spear PG, Lakeman FD, Whitley RJ. An isoelectric focusing study in herpes simplex virus encephalitis. Ann Neurol. 1988 Aug; 24(2):227-32. PMID: 3140713.
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    133. Grimaldi LM, Castagna A, Lazzarin A, Pristerá R, Bianchi G, Moroni M, Roos RP. Oligoclonal IgG bands in cerebrospinal fluid and serum during asymptomatic human immunodeficiency virus infection. Ann Neurol. 1988 Aug; 24(2):277-9. PMID: 3140714.
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    134. Baczko K, Liebert UG, Cattaneo R, Billeter MA, Roos RP, ter Meulen V. Restriction of measles virus gene expression in measles inclusion body encephalitis. J Infect Dis. 1988 Jul; 158(1):144-50. PMID: 3164746.
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    135. Grimaldi LM, Roos RP, Devare SG, Robey WG, Casey JM, Gurney ME, Apatoff BR, Lazzarin D. Restricted heterogeneity of antibody to gp120 and p24 in AIDS. J Immunol. 1988 Jul 01; 141(1):114-7. PMID: 2837506.
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    136. Ohara Y, Stein S, Fu JL, Stillman L, Klaman L, Roos RP. Molecular cloning and sequence determination of DA strain of Theiler's murine encephalomyelitis viruses. Virology. 1988 May; 164(1):245-55. PMID: 2834872.
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    137. Salazar-Grueso EF, Rosenberg RS, Roos RP. Sleep apnea in olivopontocerebellar degeneration: treatment with trazodone. Ann Neurol. 1988 Apr; 23(4):399-401. PMID: 3164175.
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    138. Grimaldi LM, Roos RP, Lazzarin A, Moroni M, Casey JM, Devare SG. Human immunodeficiency virus gp120 and p24 oligoclonal antibody in acquired immunodeficiency syndrome cerebrospinal fluid and sera. Ann N Y Acad Sci. 1988; 540:611-4. PMID: 3207289.
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    139. Clatch RJ, Pevear DC, Rozhon E, Roos RP, Miller SD, Lipton HL. Characterization and specificity of humoral immune responses to Theiler's murine encephalomyelitis virus capsid proteins. J Gen Virol. 1987 Dec; 68 ( Pt 12):3191-6. PMID: 2826657.
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    140. Cashman NR, Maselli R, Wollmann RL, Roos R, Simon R, Antel JP. Late denervation in patients with antecedent paralytic poliomyelitis. N Engl J Med. 1987 Jul 02; 317(1):7-12. PMID: 3587319.
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    141. Cashman NR, Maselli R, Wollmann RL, Roos R, Simon R, Antel JP. Post-poliomyelitis syndrome: evidence of ongoing denervation in symptomatic and asymptomatic patients. Birth Defects Orig Artic Ser. 1987; 23(4):237-9. PMID: 3620621.
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    142. Roos RP, Nalefski EA, Nitayaphan S, Variakojis R, Singh KK. An isoelectric focusing overlay study of the humoral immune response in Theiler's virus demyelinating disease. J Neuroimmunol. 1987 Jan; 13(3):305-14. PMID: 3540007.
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    143. Ohara Y, Roos R. The antibody response in Theiler's virus infection: new perspectives on multiple sclerosis. Prog Med Virol. 1987; 34:156-79. PMID: 2821576.
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    144. Salazar-Grueso E, Roos R. Sciatic endometriosis: a treatable sensorimotor mononeuropathy. Neurology. 1986 Oct; 36(10):1360-3. PMID: 3762945.
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    145. Huttenlocher PR, Picchietti DL, Roos RP, Cashman NR, Horowitz B, Horowitz MS. Intrathecal interferon in subacute sclerosing panencephalitis. Ann Neurol. 1986 Mar; 19(3):303-5. PMID: 2421637.
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    146. Nitayaphan S, Omilianowski D, Toth MM, Parks GD, Rueckert RR, Palmenberg AC, Roos RP. Relationship of Theiler's murine encephalomyelitis viruses to the cardiovirus genus of picornaviruses. Intervirology. 1986; 26(3):140-8. PMID: 3034822.
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    147. Nitayaphan S, Toth MM, Roos RP. Localization of a neutralization site of Theiler's murine encephalomyelitis viruses. J Virol. 1985 Dec; 56(3):887-95. PMID: 2415718.
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    148. Grimaldi LM, Roos RP, Nalefski EA, Arnason BG. Oligoclonal IgA bands in multiple sclerosis and subacute sclerosing panencephalitis. Neurology. 1985 Jun; 35(6):813-7. PMID: 3889705.
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    149. Stowring L, Haase AT, Petursson G, Georgsson G, Palsson P, Lutley R, Roos R, Szuchet S. Detection of visna virus antigens and RNA in glial cells in foci of demyelination. Virology. 1985 Mar; 141(2):311-8. PMID: 3002020.
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    150. Nitayaphan S, Toth MM, Roos RP. Neutralizing monoclonal antibodies to Theiler's murine encephalomyelitis viruses. J Virol. 1985 Feb; 53(2):651-7. PMID: 2578578.
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    151. Roos RP, Davis K, Meltzer HY. Immunoglobulin studies in patients with psychiatric diseases. Arch Gen Psychiatry. 1985 Feb; 42(2):124-8. PMID: 3977540.
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    152. Roos RP. B-cell abnormalities in multiple sclerosis. A hypothesis. Arch Neurol. 1985 Jan; 42(1):73-5. PMID: 3871325.
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    153. Roos RP. Genetically controlled resistance to virus infections of the central nervous system. Prog Med Genet. 1985; 6:241-76. PMID: 3014607.
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    154. Roos RP, Whitelaw PJ. Biochemical analysis of DA strain of Theiler's murine encephalomyelitis virus obtained directly from acutely infected mouse brain. Infect Immun. 1984 Jun; 44(3):642-9. PMID: 6327529.
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    155. Roos RP, Wollmann R. DA strain of Theiler's murine encephalomyelitis virus induces demyelination in nude mice. Ann Neurol. 1984 May; 15(5):494-9. PMID: 6732198.
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    156. Roos RP, Lichter M. Silver staining of cerebrospinal fluid IgG in isoelectric focusing gels. J Neurosci Methods. 1983 Aug; 8(4):375-80. PMID: 6194384.
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    157. Oger J, Roos R, Antel JP. Immunology of multiple sclerosis. Neurol Clin. 1983 Aug; 1(3):655-79. PMID: 6209537.
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    158. Roos RP. Viruses and demyelinating disease of the central nervous system. Neurol Clin. 1983 Aug; 1(3):681-700. PMID: 6209538.
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    159. Roos RP, Richards OC, Ehrenfeld E. Analysis of Theiler's virus isolates from persistently infected mouse nervous tissue. J Gen Virol. 1983 Mar; 64 Pt 3:701-6. PMID: 6298351.
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    160. Stefansson K, Marton L, Antel JP, Wollmann RL, Roos RP, Chejfec G, Arnason BG. Neuropathy accompanying IgM lambda monoclonal gammopathy. Acta Neuropathol. 1983; 59(4):255-61. PMID: 6306978.
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    161. Whitacre CC, Mattson DH, Day ED, Peterson DJ, Paterson PY, Roos RP, Arnason BG. Oligoclonal IgG in rabbits with experimental allergic encephalomyelitis: non-reactivity of the bands with sensitizing neural antigens. Neurochem Res. 1982 Oct; 7(10):1209-21. PMID: 6185858.
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    162. Roos RP, Richards OC, Green J, Ehrenfeld E. Characterization of a cell culture persistently infected with the DA strain of Theiler's murine encephalomyelitis virus. J Virol. 1982 Sep; 43(3):1118-22. PMID: 6292455.
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    163. Mattson DH, Roos RP, Hopper JE, Arnason BG. Light chain composition of CSF oligoclonal IgG bands in multiple sclerosis and subacute sclerosing panencephalitis. J Neuroimmunol. 1982 Aug; 3(1):63-76. PMID: 6808024.
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    164. Mattson DH, Roos RP, Arnason BG. Oligoclonal IgG in multiple sclerosis and subacute sclerosing panencephalitis brains. J Neuroimmunol. 1982 Jun; 2(3-4):261-76. PMID: 7085864.
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    165. Roos RP, Firestone S, Wollmann R, Variakojis D, Arnason BG. The effect of short-term and chronic immunosuppression on Theiler's virus demyelination. J Neuroimmunol. 1982 Jun; 2(3-4):223-34. PMID: 6282927.
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    166. Viola MV, Lazarus M, Antel J, Roos R. Nucleic acid probes in the study of amyotrophic lateral sclerosis. Adv Neurol. 1982; 36:317-29. PMID: 6295102.
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    167. Noronha AB, Antel JP, Roos RP, Medof ME. Circulating immune complexes in neurologic disease. Neurology. 1981 Nov; 31(11):1402-7. PMID: 7198188.
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    168. Roos RP, Graves MC, Wollmann RL, Chilcote RR, Nixon J. Immunologic and virologic studies of measles inclusion body encephalitis in an immunosuppressed host: the relationship to subacute sclerosing panencephalitis. Neurology. 1981 Oct; 31(10):1263-70. PMID: 7202137.
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    169. Mattson DH, Roos RP, Arnason BG. Comparison of agar gel electrophoresis and isoelectric focusing in multiple sclerosis and subacute sclerosing panencephalitis. Ann Neurol. 1981 Jan; 9(1):34-41. PMID: 6163394.
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    170. Whitacre CC, Mattson DH, Paterson PY, Roos RP, Peterson DJ, Arnason BG. Cerebrospinal fluid and serum oligoclonal IgG bands in rabbits with experiment allergic encephalomyelitis. Neurochem Res. 1981 Jan; 6(1):87-96. PMID: 6164000.
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    171. Mattson DH, Roos RP, Arnason BG. Immunoperoxidase staining of cerebrospinal fluid IgG in isoelectric focusing gels: a sensitive new technique. J Neurosci Methods. 1980 Oct; 3(1):67-75. PMID: 6164880.
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    172. Mattson DH, Roos RP, Arnason BG. Isoelectric focusing of IgG eluted from multiple sclerosis and subacute sclerosing panencephalitis brains. Nature. 1980 Sep 25; 287(5780):335-7. PMID: 7421992.
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    173. Stefansson K, Antel JP, Oger J, Burns J, Noronha AB, Roos RP, Arnason BG, Gudmundsson G. Autosomal dominant cerebrovascular amyloidosis: properties of peripheral blood lymphocytes. Ann Neurol. 1980 May; 7(5):436-40. PMID: 7396423.
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    174. Roos RP, Viola MV, Wollmann R, Hatch MH, Antel JP. Amyotrophic lateral sclerosis with antecedent poliomyelitis. Arch Neurol. 1980 May; 37(5):312-3. PMID: 6247998.
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    175. Noronha AB, Roos RP, Antel JP, Arnason BG. Huntington's disease: abnormality of lymphocyte capping. Ann Neurol. 1979 Nov; 6(5):447-50. PMID: 160212.
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    176. Viola MV, Myers JC, Gann KL, Gibbs JC, Roos RP. Failure to detect poliovirus genetic information in amyotrophic lateral sclerosis. Ann Neurol. 1979 Apr; 5(4):402-3. PMID: 220904.
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    177. Papathanasios B, Dendrinos C, Mposinakos M. [Osteogenesis imperfecta associated with dentinogenesis imperfecta]. Stomatologia (Athenai). 1979 Mar-Apr; 36(2):90-4. PMID: 288222.
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    178. Roos RP, Wollmann R. Non-productive paramyxovirus infection: Nariva virus infection in hamsters. Arch Virol. 1979; 62(3):229-40. PMID: 518307.
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    179. Roos RP, Griffin DE, Johnson RT. Determinants of measles virus (hamster neurotropic strain) replication in mouse brain. J Infect Dis. 1978 Jun; 137(6):722-7. PMID: 207790.
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    180. Pericak-Vance MA, Conneally PM, Merritt AD, Roos R, Norton JA, Vance JM. Genetic linkage studies in Huntington disease. Cytogenet Cell Genet. 1978; 22(1-6):640-5. PMID: 156628.
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    181. Roos RP, Kirkpatrick C, Gadoth N, Berman W, Rary J. An immunological and cytogenetic investigation of tuberous sclerosis. Ann Neurol. 1977 Feb; 1(2):192-4. PMID: 889305.
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    182. Roos RP, Johnson RT. Viruses and dementia. Contemp Neurol Ser. 1977; 15:93-112. PMID: 336275.
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    183. Bobowick AR, Brody JA, Matthews MR, Roos R, Gajdusek DC. Creutzfeldt-Jakob disease: a case-control study. Am J Epidemiol. 1973 Nov; 98(5):381-94. PMID: 4583406.
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    184. Roos R, Gajdusek DC, Gibbs CJ. The clinical characteristics of transmissible Creutzfeldt-Jakob disease. Brain. 1973; 96(1):1-20. PMID: 4633062.
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    185. Brown P, Hooks J, Roos R, Gajdusek DC, Gibbs CJ. Attempt to identify the agent for Creutzfeldt-Jakob disease by CF antibody relationship to known viruses. Nat New Biol. 1972 Feb 02; 235(57):149-52. PMID: 4333969.
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    186. Roos R, Chou SM, Rogers NG, Basnight M, Gajdusek DC. Isolation of an adenovirus 32 strain from human brain in a case of subacute encephalitis. Proc Soc Exp Biol Med. 1972 Feb; 139(2):636-40. PMID: 4333787.
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