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Diarmuid M. Moran

InstitutionUniversity of Chicago
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yu HA, Spira A, Horn L, Weiss J, West H, Giaccone G, Evans T, Kelly RJ, Desai B, Krivoshik A, Moran D, Poondru S, Jie F, Aoyama K, Keating A, Oxnard GR. A Phase I, Dose Escalation Study of Oral ASP8273 in Patients with Non-small Cell Lung Cancers with Epidermal Growth Factor Receptor Mutations. Clin Cancer Res. 2017 Dec 15; 23(24):7467-7473. PMID: 28954786; PMCID: PMC8788622.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    2. Hamm CA, Moran D, Rao K, Trusk PB, Pry K, Sausen M, Velculescu VE, Cristofanilli M, Bacus S, Jones S. Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors. Mol Cancer Ther. 2016 07; 15(7):1746-56. PMID: 27196778.
      Citations: 29     Fields:    Translation:HumansCells
    3. Doherty KR, Talbert DR, Trusk PB, Moran DM, Shell SA, Bacus S. Structural and functional screening in human induced-pluripotent stem cell-derived cardiomyocytes accurately identifies cardiotoxicity of multiple drug types. Toxicol Appl Pharmacol. 2015 May 15; 285(1):51-60. PMID: 25841593.
      Citations: 36     Fields:    Translation:HumansCells
    4. Talbert DR, Doherty KR, Trusk PB, Moran DM, Shell SA, Bacus S. A multi-parameter in vitro screen in human stem cell-derived cardiomyocytes identifies ponatinib-induced structural and functional cardiac toxicity. Toxicol Sci. 2015 Jan; 143(1):147-55. PMID: 25304212.
      Citations: 31     Fields:    Translation:HumansCells
    5. Moran DM, Trusk PB, Pry K, Paz K, Sidransky D, Bacus SS. KRAS mutation status is associated with enhanced dependency on folate metabolism pathways in non-small cell lung cancer cells. Mol Cancer Ther. 2014 Jun; 13(6):1611-24. PMID: 24688052.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    6. Breen MJ, Moran DM, Liu W, Huang X, Vary CP, Bergan RC. Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors. PLoS One. 2013; 8(8):e72407. PMID: 23967299; PMCID: PMC3742533.
      Citations: 12     Fields:    Translation:HumansCells
    7. Doherty KR, Wappel RL, Talbert DR, Trusk PB, Moran DM, Kramer JW, Brown AM, Shell SA, Bacus S. Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes. Toxicol Appl Pharmacol. 2013 Oct 01; 272(1):245-55. PMID: 23707608.
      Citations: 72     Fields:    Translation:HumansCells
    8. Moran DM, Maki CG. Nutlin-3a induces cytoskeletal rearrangement and inhibits the migration and invasion capacity of p53 wild-type cancer cells. Mol Cancer Ther. 2010 Apr; 9(4):895-905. PMID: 20371712; PMCID: PMC3075611.
      Citations: 15     Fields:    Translation:HumansCells
    9. Moran DM, Shen H, Maki CG. Puromycin-based vectors promote a ROS-dependent recruitment of PML to nuclear inclusions enriched with HSP70 and Proteasomes. BMC Cell Biol. 2009 May 01; 10:32. PMID: 19409099; PMCID: PMC2685373.
      Citations: 13     Fields:    Translation:HumansCells
    10. Shen H, Moran DM, Maki CG. Transient nutlin-3a treatment promotes endoreduplication and the generation of therapy-resistant tetraploid cells. Cancer Res. 2008 Oct 15; 68(20):8260-8. PMID: 18922897; PMCID: PMC2674275.
      Citations: 37     Fields:    Translation:HumansCells
    11. Moran DM, Gawlak G, Jayaprakash MS, Mayar S, Maki CG. Geldanamycin promotes premature mitotic entry and micronucleation in irradiated p53/p21 deficient colon carcinoma cells. Oncogene. 2008 Sep 18; 27(42):5567-77. PMID: 18504430; PMCID: PMC2811229.
      Citations: 14     Fields:    Translation:HumansCells
    12. McKillop IH, Moran DM, Jin X, Koniaris LG. Molecular pathogenesis of hepatocellular carcinoma. J Surg Res. 2006 Nov; 136(1):125-35. PMID: 17023002.
      Citations: 38     Fields:    Translation:HumansAnimals
    13. Moran DM, Koniaris LG, Jablonski EM, Cahill PA, Halberstadt CR, McKillop IH. Microencapsulation of engineered cells to deliver sustained high circulating levels of interleukin-6 to study hepatocellular carcinoma progression. Cell Transplant. 2006; 15(8-9):785-98. PMID: 17269449.
      Citations: 8     Fields:    Translation:AnimalsCells
    14. Moran DM, Mayes N, Koniaris LG, Cahill PA, McKillop IH. Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma. Liver Int. 2005 Apr; 25(2):445-57. PMID: 15780071.
      Citations: 9     Fields:    Translation:AnimalsCells
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