The University of Chicago Header Logo

Ralph R. Weichselbaum

TitleProfessor
InstitutionUniversity of Chicago
DepartmentRadiation and Cellular Oncology
AddressChicago IL 60637
Email
vCardDownload vCard

    Collapse Biography 
    Collapse education and training
    University of Wisconsin, Madison WIBS06/1967Liberal Arts
    University of Illinois, Chicago ILMD06/1971Medicine

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tran MC, Hasan Y, Wang A, Yenice K, Partouche J, Stock W, Larson RA, Kosuri S, LaBelle JL, Kline J, Riedell PA, Artz AS, Weichselbaum R, Bishop MR, Aydogan B, Liu H. A phase 1 trial utilizing TMI with fludarabine-melphalan in patients with hematologic malignancies undergoing second allo-SCT. Blood Adv. 2023 02 14; 7(3):285-292. PMID: 35851593; PMCID: PMC9898602.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    2. Spurr LF, Weichselbaum RR, Pitroda SP. Author Correction: Tumor aneuploidy predicts survival following immunotherapy across multiple cancers. Nat Genet. 2023 Feb; 55(2):355. PMID: 36596861.
      Citations:    Fields:    
    3. Liu J, Jiang X, Feng X, Lee MJ, Li Y, Mao J, Weichselbaum RR, Lin W. A Three-in-One Nanoscale Coordination Polymer for Potent Chemo-Immunotherapy. Small Methods. 2023 05; 7(5):e2201437. PMID: 36638256; PMCID: PMC10192092.
      Citations: 1     Fields:    Translation:HumansAnimals
    4. Zhen W, Weichselbaum RR, Lin W. Nanoparticle-Mediated Radiotherapy Remodels the Tumor Microenvironment to Enhance Antitumor Efficacy. Adv Mater. 2022 Dec 16; e2206370. PMID: 36524978.
      Citations: 1     Fields:    
    5. Dhiman A, Vining CC, Witmer HDD, Sood D, Shergill A, Kindler H, Roggin KK, Posner MC, Ahmed OS, Liauw S, Pitroda S, Liao CY, Karrison T, Weichselbaum R, Polite B, Eng OS, Catenacci DVT, Turaga KK. ASO Visual Abstract: Phase II Prospective Open-Label Randomized Controlled Trial Comparing Standard of Care Chemotherapy with and without Sequential Cytoreductive Interventions for Patients with Oligometastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels. Ann Surg Oncol. 2022 12; 29(Suppl 3):616-617. PMID: 35930113.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    6. Spurr LF, Martinez CA, Kang W, Chen M, Zha Y, Hseu R, Gutiontov SI, Turchan WT, Lynch CM, Pointer KB, Chang P, Murgu S, Husain AN, Cody B, Vokes EE, Bestvina CM, Patel JD, Diehn M, Gajewski TF, Weichselbaum RR, Chmura SJ, Pitroda SP. Highly aneuploid non-small cell lung cancer shows enhanced responsiveness to concurrent radiation and immune checkpoint blockade. Nat Cancer. 2022 Nov 28. PMID: 36443406.
      Citations: 5     Fields:    
    7. Spurr LF, Weichselbaum RR, Pitroda SP. Tumor aneuploidy predicts survival following immunotherapy across multiple cancers. Nat Genet. 2022 Dec; 54(12):1782-1785. PMID: 36443443.
      Citations: 4     Fields:    
    8. Ni K, Xu Z, Culbert A, Luo T, Guo N, Yang K, Pearson E, Preusser B, Wu T, La Riviere P, Weichselbaum RR, Spiotto MT, Lin W. Author Correction: Synergistic checkpoint-blockade and radiotherapy-radiodynamic therapy via an immunomodulatory nanoscale metal-organic framework. Nat Biomed Eng. 2022 Nov 11. PMID: 36369378.
      Citations:    Fields:    
    9. Yang K, Han W, Jiang X, Piffko A, Bugno J, Han C, Li S, Liang H, Xu Z, Zheng W, Wang L, Wang J, Huang X, Ting JPY, Fu YX, Lin W, Weichselbaum RR. Zinc cyclic di-AMP nanoparticles target and suppress tumours via endothelial STING activation and tumour-associated macrophage reinvigoration. Nat Nanotechnol. 2022 Oct 27. PMID: 36302963.
      Citations: 2     Fields:    
    10. Spurr LF, Martinez CA, Katipally RR, Iyer SC, Pugh SA, Bridgewater JA, Primrose JN, Domingo E, Maughan TS, D'Angelica MI, Talamonti M, Posner MC, Connell PP, Weichselbaum RR, Pitroda SP. A proliferative subtype of colorectal liver metastases exhibits hypersensitivity to cytotoxic chemotherapy. NPJ Precis Oncol. 2022 Oct 14; 6(1):72. PMID: 36241710; PMCID: PMC9568565.
      Citations:    
    11. Turchan WT, Pitroda SP, Weichselbaum RR. Beyond the Visible Spectrum: Considering the Oligometastatic Hypothesis in the Light of a New Era. Int J Radiat Oncol Biol Phys. 2022 11 15; 114(4):581-586. PMID: 36244394.
      Citations:    Fields:    Translation:Humans
    12. Li Y, Jiang X, Luo T, Xia J, Lee MJ, Weichselbaum RR, Lin W. TLR3 agonist nanoscale coordination polymer synergizes with immune checkpoint blockade for immunotherapy of cancer. Biomaterials. 2022 11; 290:121831. PMID: 36240687.
      Citations: 1     Fields:    Translation:Animals
    13. Lyden D, Ghajar CM, Correia AL, Aguirre-Ghiso JA, Cai S, Rescigno M, Zhang P, Hu G, Fendt SM, Boire A, Weichselbaum RR, Katipally RR. Metastasis. Cancer Cell. 2022 08 08; 40(8):787-791. PMID: 35944497; PMCID: PMC9924435.
      Citations: 2     Fields:    Translation:Humans
    14. Katipally RR, Pitroda SP, Juloori A, Chmura SJ, Weichselbaum RR. The oligometastatic spectrum in the era of improved detection and modern systemic therapy. Nat Rev Clin Oncol. 2022 09; 19(9):585-599. PMID: 35831494.
      Citations: 7     Fields:    Translation:Humans
    15. Jiang X, Han W, Liu J, Mao J, Lee MJ, Rodriguez M, Li Y, Luo T, Xu Z, Yang K, Bissonnette M, Weichselbaum RR, Lin W. Tumor-Activatable Nanoparticles Target Low-Density Lipoprotein Receptor to Enhance Drug Delivery and Antitumor Efficacy. Adv Sci (Weinh). 2022 08; 9(24):e2201614. PMID: 35748191; PMCID: PMC9404402.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    16. Bernal GM, Wu L, Voce DJ, Weichselbaum RR, Yamini B. p52 signaling promotes cellular senescence. Cell Biosci. 2022 Apr 04; 12(1):43. PMID: 35379326; PMCID: PMC8981737.
      Citations:    
    17. Williamson AJ, Jacobson R, van Praagh JB, Gaines S, Koo HY, Lee B, Chan WC, Weichselbaum R, Alverdy JC, Zaborina O, Shogan BD. Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells. Neoplasia. 2022 05; 27:100787. PMID: 35366466; PMCID: PMC8971311.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    18. Lakiza O, Lutze J, Vogle A, Williams J, Abukdheir A, Miller P, Liao C', Pitroda SP, Martinez C, Olivas A, Setia N, Kron SJ, Weichselbaum RR, Keutgen XM. Loss of MEN1 function impairs DNA repair capability of pancreatic neuroendocrine tumors. Endocr Relat Cancer. 2022 03 21; 29(4):225-239. PMID: 35171113; PMCID: PMC9045673.
      Citations:    Fields:    Translation:HumansCells
    19. Turchan WT, Pitroda SP, Weichselbaum RR. Combined radio-immunotherapy: An opportunity to increase the therapeutic ratio of oligometastasis-directed radiotherapy. Neoplasia. 2022 05; 27:100782. PMID: 35303578; PMCID: PMC8931441.
      Citations: 1     Fields:    Translation:Humans
    20. Chang JY, Verma V, Weichselbaum RR. Immunotherapy for the Neoadjuvant Management of Resectable Intrathoracic Cancers: Let's Not Forget Radiotherapy. JAMA Oncol. 2022 03 01; 8(3):333-334. PMID: 34989790.
      Citations:    Fields:    Translation:Humans
    21. Ni K, Xu Z, Culbert A, Luo T, Guo N, Yang K, Pearson E, Preusser B, Wu T, La Riviere P, Weichselbaum RR, Spiotto MT, Lin W. Synergistic checkpoint-blockade and radiotherapy-radiodynamic therapy via an immunomodulatory nanoscale metal-organic framework. Nat Biomed Eng. 2022 02; 6(2):144-156. PMID: 35190678; PMCID: PMC9462448.
      Citations: 5     Fields:    Translation:Animals
    22. Dhiman A, Vining CC, Witmer HDD, Sood D, Shergill A, Kindler H, Roggin KK, Posner MC, Ahmed OS, Liauw S, Pitroda S, Liao CY, Karrison T, Weichselbaum R, Polite B, Eng OS, Catenacci DVT, Turaga KK. Phase II Prospective, Open-Label Randomized Controlled Trial Comparing Standard of Care Chemotherapy With and Without Sequential Cytoreductive Interventions for Patients with Oligometastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor Deoxyribose Nucleic Acid (ctDNA) Levels. Ann Surg Oncol. 2022 Jan 05. PMID: 34988836; PMCID: PMC8730296.
      Citations:    Fields:    
    23. Pointer KB, Pitroda SP, Weichselbaum RR. Radiotherapy and immunotherapy: open questions and future strategies. Trends Cancer. 2022 01; 8(1):9-20. PMID: 34740553.
      Citations: 7     Fields:    Translation:Humans
    24. Pointer KB, Katipally RR, Bestvina CM, Juloori A, Partouche J, Patel JD, Pitroda SP, Vokes EE, Weichselbaum RR, Chmura SJ. Evaluation of Initial Metastatic Tumor Location and Radiation Response to Determine Outcomes in Patients Who Received Combination Stereotactic Body Radiotherapy and Immunotherapy for NSCLC. Int J Radiat Oncol Biol Phys. 2021 Nov 01; 111(3S):e449. PMID: 34701479.
      Citations:    
    25. Guo N, Ni K, Luo T, Lan G, Arina A, Xu Z, Mao J, Weichselbaum RR, Spiotto M, Lin W. Reprogramming of Neutrophils as Non-canonical Antigen Presenting Cells by Radiotherapy-Radiodynamic Therapy to Facilitate Immune-Mediated Tumor Regression. ACS Nano. 2021 11 23; 15(11):17515-17527. PMID: 34709030.
      Citations: 3     Fields:    Translation:AnimalsCells
    26. Gutiontov SI, Turchan WT, Spurr LF, Rouhani SJ, Chervin CS, Steinhardt G, Lager AM, Wanjari P, Malik R, Connell PP, Chmura SJ, Juloori A, Hoffman PC, Ferguson MK, Donington JS, Patel JD, Vokes EE, Weichselbaum RR, Bestvina CM, Segal JP, Pitroda SP. CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer. Sci Rep. 2021 10 08; 11(1):20059. PMID: 34625620; PMCID: PMC8501138.
      Citations: 26     Fields:    Translation:Humans
    27. Li Y, Ni K, Chan C, Guo N, Luo T, Han W, Culbert A, Weichselbaum RR, Lin W. Dimethylaminomicheliolide Sensitizes Cancer Cells to Radiotherapy for Synergistic Combination with Immune Checkpoint Blockade. Adv Ther (Weinh). 2022 Jan; 5(1). PMID: 35812344; PMCID: PMC9269983.
      Citations:    
    28. Turchan WT, Pitroda SP, Weichselbaum RR. Radiotherapy and Immunotherapy Combinations in the Treatment of Patients with Metastatic Disease: Current Status and Future Focus. Clin Cancer Res. 2021 10 01; 27(19):5188-5194. PMID: 34140404.
      Citations: 3     Fields:    Translation:Humans
    29. Bestvina CM, Pointer KB, Karrison T, Al-Hallaq H, Hoffman PC, Jelinek MJ, Juloori A, Melotek JM, Murgu S, Partouche J, Vokes EE, Weichselbaum RR, Pitroda SP, Patel JD, Chmura SJ. A Phase 1 Trial of Concurrent or Sequential Ipilimumab, Nivolumab, and Stereotactic Body Radiotherapy in Patients With Stage IV NSCLC Study. J Thorac Oncol. 2022 01; 17(1):130-140. PMID: 34500113.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    30. Turchan WT, Pitroda SP, Weichselbaum RR. Treatment of Cancer with Radio-Immunotherapy: What We Currently Know and What the Future May Hold. Int J Mol Sci. 2021 Sep 03; 22(17). PMID: 34502479; PMCID: PMC8431248.
      Citations: 1     Fields:    Translation:Humans
    31. Weichselbaum RR, Pitroda SP. Immunoradiotherapy goes club(bing). Nat Cancer. 2021 09; 2(9):871-872. PMID: 35121867.
      Citations:    Fields:    
    32. Akama-Garren EH, Morris ZS, Sikora AG, Weichselbaum R, Schoenfeld JD. Prospective Clinical Investigation of the Efficacy of Combination Radiation Therapy With Immune Checkpoint Inhibition. Int J Radiat Oncol Biol Phys. 2021 12 01; 111(5):1165-1175. PMID: 34411638.
      Citations: 3     Fields:    Translation:Humans
    33. Gutiontov S, Pitroda S, Weichselbaum R. The Spectrum of Metastasis: An Opportunity for Cure? Semin Radiat Oncol. 2021 07; 31(3):174-179. PMID: 34090643.
      Citations: 3     Fields:    Translation:Humans
    34. Foster CC, Fleming GF, Karrison TG, Liao CY, Desai AV, Moroney JW, Ratain MJ, Nanda R, Polite BN, Hahn OM, O'Donnell PH, Vokes EE, Kindler HL, Hseu R, Janisch LA, Dai J, Hoffman MD, Weichselbaum RR, Pitroda SP, Chmura SJ, Luke JJ. Phase I Study of Stereotactic Body Radiotherapy plus Nivolumab and Urelumab or Cabiralizumab in Advanced Solid Tumors. Clin Cancer Res. 2021 10 15; 27(20):5510-5518. PMID: 34168049.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    35. Rao E, Hou Y, Huang X, Wang L, Wang J, Zheng W, Yang H, Yu X, Yang K, Bugno J, Ding X, Vokes E, Fu YX, Weichselbaum RR, Liang HL. All-trans retinoic acid overcomes solid tumor radioresistance by inducing inflammatory macrophages. Sci Immunol. 2021 06 15; 6(60). PMID: 34723044; PMCID: PMC8550472.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    36. Ding XC, Wang LL, Zhang XD, Xu JL, Li PF, Liang H, Zhang XB, Xie L, Zhou ZH, Yang J, Weichselbaum RR, Yu JM, Hu M. The relationship between expression of PD-L1 and HIF-1a in glioma cells under hypoxia. J Hematol Oncol. 2021 06 12; 14(1):92. PMID: 34118979; PMCID: PMC8199387.
      Citations: 29     Fields:    Translation:HumansCells
    37. Keutgen XM, Ornell KJ, Vogle A, Lakiza O, Williams J, Miller P, Mistretta KS, Setia N, Weichselbaum RR, Coburn JM. Sunitinib-Loaded Chondroitin Sulfate Hydrogels as a Novel Drug-Delivery Mechanism for the Treatment of Pancreatic Neuroendocrine Tumors. Ann Surg Oncol. 2021 Dec; 28(13):8532-8543. PMID: 34091777.
      Citations: 1     Fields:    Translation:AnimalsCells
    38. Han C, Godfrey V, Liu Z, Han Y, Liu L, Peng H, Weichselbaum RR, Zaki H, Fu YX. The AIM2 and NLRP3 inflammasomes trigger IL-1-mediated antitumor effects during radiation. Sci Immunol. 2021 05 07; 6(59). PMID: 33963060.
      Citations: 10     Fields:    Translation:AnimalsCells
    39. Voce DJ, Bernal GM, Cahill KE, Wu L, Mansour N, Crawley CD, Campbell PS, Arina A, Weichselbaum RR, Yamini B. CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma. Sci Rep. 2021 03 11; 11(1):5665. PMID: 33707466; PMCID: PMC7952566.
      Citations: 5     Fields:    Translation:HumansCells
    40. Si W, Liang H, Bugno J, Xu Q, Ding X, Yang K, Fu Y, Weichselbaum RR, Zhao X, Wang L. Lactobacillus rhamnosus GG induces cGAS/STING- dependent type I interferon and improves response to immune checkpoint blockade. Gut. 2022 03; 71(3):521-533. PMID: 33685966; PMCID: PMC8710942.
      Citations: 32     Fields:    Translation:AnimalsCells
    41. Yang K, Hou Y, Zhang Y, Liang H, Sharma A, Zheng W, Wang L, Torres R, Tatebe K, Chmura SJ, Pitroda SP, Gilbert JA, Fu YX, Weichselbaum RR. Suppression of local type I interferon by gut microbiota-derived butyrate impairs antitumor effects of ionizing radiation. J Exp Med. 2021 03 01; 218(3). PMID: 33496784; PMCID: PMC7844434.
      Citations: 20     Fields:    Translation:AnimalsCells
    42. Hou Y, Liang HL, Yu X, Liu Z, Cao X, Rao E, Huang X, Wang L, Li L, Bugno J, Fu Y, Chmura SJ, Wu W, Luo SZ, Zheng W, Arina A, Jutzy J, McCall AR, Vokes EE, Pitroda SP, Fu YX, Weichselbaum RR. Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity. Sci Transl Med. 2021 02 24; 13(582). PMID: 33627484; PMCID: PMC8710940.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    43. Gutiontov SI, Pitroda SP, Tran PT, Weichselbaum RR. (Oligo)metastasis as a Spectrum of Disease. Cancer Res. 2021 05 15; 81(10):2577-2583. PMID: 33452011.
      Citations: 6     Fields:    Translation:HumansAnimals
    44. Deutsch E, Chargari C, Weichselbaum RR, Levy A. Drug-Radiotherapy Combination Trial Developments-Response. Clin Cancer Res. 2021 01 01; 27(1):356. PMID: 33397680.
      Citations:    Fields:    Translation:Humans
    45. Redler G, Pearson E, Liu X, Gertsenshteyn I, Epel B, Pelizzari C, Aydogan B, Weichselbaum R, Halpern HJ, Wiersma RD. Small Animal IMRT Using 3D-Printed Compensators. Int J Radiat Oncol Biol Phys. 2021 06 01; 110(2):551-565. PMID: 33373659; PMCID: PMC8122034.
      Citations: 3     Fields:    Translation:Animals
    46. B?ttinger P, Schreiber K, Hyjek E, Krausz T, Spiotto MT, Steiner M, Idel C, Booras H, Beck-Engeser G, Riederer J, Willimsky G, Wolf SP, Karrison T, Jensen E, Weichselbaum RR, Nakamura Y, Yew PY, Lambert PF, Kurita T, Kiyotani K, Leisegang M, Schreiber H. Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens. Carcinogenesis. 2020 11 13; 41(11):1605-1615. PMID: 32221533; PMCID: PMC7896110.
      Citations: 5     Fields:    Translation:AnimalsCells
    47. Prasanna PG, Woloschak GE, DiCarlo AL, Buchsbaum JC, Schaue D, Chakravarti A, Cucinotta FA, Formenti SC, Guha C, Hu DJ, Khan MK, Kirsch DG, Krishnan S, Leitner WW, Marples B, McBride W, Mehta MP, Rafii S, Sharon E, Sullivan JM, Weichselbaum RR, Ahmed MM, Vikram B, Coleman CN, Held KD. Low-Dose Radiation Therapy (LDRT) for COVID-19: Benefits or Risks? Radiat Res. 2020 11 10; 194(5):452-464. PMID: 33045077; PMCID: PMC8009137.
      Citations: 17     Fields:    Translation:HumansAnimalsPHPublic Health
    48. Gutiontov SI, Pitroda SP, Weichselbaum RR. Oligometastasis: Past, Present, Future. Int J Radiat Oncol Biol Phys. 2020 11 01; 108(3):530-538. PMID: 32976785.
      Citations: 8     Fields:    Translation:Humans
    49. Ding XC, Wang LL, Zhu YF, Li YD, Nie SL, Yang J, Liang H, Weichselbaum RR, Yu JM, Hu M. The Change of Soluble Programmed Cell Death-Ligand 1 in Glioma Patients Receiving Radiotherapy and Its Impact on Clinical Outcomes. Front Immunol. 2020; 11:580335. PMID: 33224142; PMCID: PMC7668030.
      Citations: 5     Fields:    Translation:HumansCells
    50. Zheng W, Ranoa DRE, Huang X, Hou Y, Yang K, Poli EC, Beckett MA, Fu YX, Weichselbaum RR. RIG-I-Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy. Cancer Res. 2020 12 15; 80(24):5633-5641. PMID: 33087322.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    51. Luke JJ, Onderdonk BE, Bhave SR, Karrison T, Lemons JM, Chang P, Zha Y, Carll T, Krausz T, Huang L, Martinez C, Janisch LA, Hseu RD, Moroney JW, Patel JD, Khodarev NN, Salama JK, Ott PA, Fleming GF, Gajewski TF, Weichselbaum RR, Pitroda SP, Chmura SJ. Improved Survival Associated with Local Tumor Response Following Multisite Radiotherapy and Pembrolizumab: Secondary Analysis of a Phase I Trial. Clin Cancer Res. 2020 12 15; 26(24):6437-6444. PMID: 33028595; PMCID: PMC8561652.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    52. Wu L, Crawley CD, Garofalo A, Nichols JW, Campbell PA, Khramtsova GF, Olopade OI, Weichselbaum RR, Yamini B. p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability. Nat Commun. 2020 10 06; 11(1):5007. PMID: 33024116; PMCID: PMC7538584.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    53. Ni K, Lan G, Guo N, Culbert A, Luo T, Wu T, Weichselbaum RR, Lin W. Nanoscale metal-organic frameworks for x-ray activated in situ cancer vaccination. Sci Adv. 2020 10; 6(40). PMID: 33008911; PMCID: PMC7852401.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    54. Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ. Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nat Commun. 2020 09 14; 11(1):4591. PMID: 32929084; PMCID: PMC7490264.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    55. Gutiontov SI, Pitroda SP, Chmura SJ, Arina A, Weichselbaum RR. Cytoreduction and the Optimization Of Immune Checkpoint Inhibition with Radiation Therapy. Int J Radiat Oncol Biol Phys. 2020 09 01; 108(1):17-26. PMID: 32819613.
      Citations: 11     Fields:    Translation:Humans
    56. Bryan DS, Stack M, Krysztofiak K, Cichon U, Thomas DG, Surcel A, Schiffhauer ES, Beckett MA, Khodarev NN, Xue L, Poli EC, Pearson AT, Posner MC, Robinson DN, Rock RS, Weichselbaum RR. 4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis. Proc Natl Acad Sci U S A. 2020 09 08; 117(36):22423-22429. PMID: 32848073; PMCID: PMC7486788.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    57. Liauw SL, Ham SA, Das LC, Rudra S, Packiam VT, Koshy M, Weichselbaum RR, Becker YT, Bodzin AS, Eggener SE. Prostate Cancer Outcomes Following Solid-Organ Transplantation: A SEER-Medicare Analysis. J Natl Cancer Inst. 2020 08 01; 112(8):847-854. PMID: 31728517; PMCID: PMC8453608.
      Citations: 11     Fields:    Translation:Humans
    58. Foster CC, Fan M, Lee NY, Yom SS, Heaton CM, Deraniyagala R, Amdur R, Weichselbaum RR, Haraf DJ. Is It Worth It? Consequences of Definitive Head and Neck Reirradiation. Semin Radiat Oncol. 2020 Jul; 30(3):212-217. PMID: 32503785.
      Citations: 2     Fields:    Translation:Humans
    59. Kirsch DG, Diehn M, Cucinotta FA, Weichselbaum R. Response Letter: Radiation therapy for COVID-19 pneumopathy. Radiother Oncol. 2020 08; 149:238-239. PMID: 32505722; PMCID: PMC7272168.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    60. Chen C, Liao Z, Chmura SJ, Weichselbaum RR. Coronavirus Disease 2019 Infection Prevention and Control Practices in Wuhan Radiation Therapy. Adv Radiat Oncol. 2020 Jul-Aug; 5(4):637-639. PMID: 32775773; PMCID: PMC7234952.
      Citations: 1     
    61. Chargari C, Levy A, Paoletti X, Soria JC, Massard C, Weichselbaum RR, Deutsch E. Methodological Development of Combination Drug and Radiotherapy in Basic and Clinical Research. Clin Cancer Res. 2020 09 15; 26(18):4723-4736. PMID: 32409306; PMCID: PMC7717106.
      Citations: 9     Fields:    Translation:Humans
    62. Kirsch DG, Diehn M, Cucinotta FA, Weichselbaum R. Lack of supporting data make the risks of a clinical trial of radiation therapy as a treatment for COVID-19 pneumonia unacceptable. Radiother Oncol. 2020 06; 147:217-220. PMID: 32413531; PMCID: PMC7215144.
      Citations: 24     Fields:    
    63. Kim SM, DeFazio JR, Hyoju SK, Sangani K, Keskey R, Krezalek MA, Khodarev NN, Sangwan N, Christley S, Harris KG, Malik A, Zaborin A, Bouziat R, Ranoa DR, Wiegerinck M, Ernest JD, Shakhsheer BA, Fleming ID, Weichselbaum RR, Antonopoulos DA, Gilbert JA, Barreiro LB, Zaborina O, Jabri B, Alverdy JC. Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity. Nat Commun. 2020 05 11; 11(1):2354. PMID: 32393794; PMCID: PMC7214422.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    64. Shi Y, Zheng W, Yang K, Harris KG, Ni K, Xue L, Lin W, Chang EB, Weichselbaum RR, Fu YX. Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling. J Exp Med. 2020 05 04; 217(5). PMID: 32142585; PMCID: PMC7201921.
      Citations: 69     Fields:    Translation:AnimalsCells
    65. Szymura SJ, Bernal GM, Wu L, Zhang Z, Crawley CD, Voce DJ, Campbell PA, Ranoa DE, Weichselbaum RR, Yamini B. DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-?B and sensitize to alkylating chemotherapy. BMC Biol. 2020 03 24; 18(1):32. PMID: 32209106; PMCID: PMC7093963.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    66. Hasan Y, Furtado L, Tergas A, Lee N, Brooks R, McCall A, Golden D, Jolly S, Fleming G, Morrow M, Kraynyak K, Sylvester A, Arif F, Levin M, Schwartz D, Boyer J, Skolnik J, Esser M, Kumar R, Bagarazzi M, Weichselbaum R, Spiotto M. A Phase 1 Trial Assessing the Safety and Tolerability of a Therapeutic DNA Vaccination Against HPV16 and HPV18 E6/E7 Oncogenes After Chemoradiation for Cervical Cancer. Int J Radiat Oncol Biol Phys. 2020 07 01; 107(3):487-498. PMID: 32151670; PMCID: PMC7705948.
      Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
    67. Foster CC, Pitroda SP, Weichselbaum RR. Definition, Biology, and History of Oligometastatic and Oligoprogressive Disease. Cancer J. 2020 Mar/Apr; 26(2):96-99. PMID: 32205532.
      Citations: 10     Fields:    Translation:Humans
    68. Arina A, Gutiontov SI, Weichselbaum RR. Radiotherapy and Immunotherapy for Cancer: From "Systemic" to "Multisite". Clin Cancer Res. 2020 06 15; 26(12):2777-2782. PMID: 32047000.
      Citations: 45     Fields:    Translation:HumansAnimals
    69. Gaines S, van Praagh JB, Williamson AJ, Jacobson RA, Hyoju S, Zaborin A, Mao J, Koo HY, Alpert L, Bissonnette M, Weichselbaum R, Gilbert J, Chang E, Hyman N, Zaborina O, Shogan BD, Alverdy JC. Western Diet Promotes Intestinal Colonization by Collagenolytic Microbes and Promotes Tumor Formation After Colorectal Surgery. Gastroenterology. 2020 03; 158(4):958-970.e2. PMID: 31655031; PMCID: PMC7062578.
      Citations: 21     Fields:    Translation:AnimalsCells
    70. Arina A, Beckett M, Fernandez C, Zheng W, Pitroda S, Chmura SJ, Luke JJ, Forde M, Hou Y, Burnette B, Mauceri H, Lowy I, Sims T, Khodarev N, Fu YX, Weichselbaum RR. Tumor-reprogrammed resident T cells resist radiation to control tumors. Nat Commun. 2019 09 02; 10(1):3959. PMID: 31477729; PMCID: PMC6718618.
      Citations: 77     Fields:    Translation:AnimalsCells
    71. Pitroda SP, Weichselbaum RR. Integrated molecular and clinical staging defines the spectrum of metastatic cancer. Nat Rev Clin Oncol. 2019 09; 16(9):581-588. PMID: 31092903.
      Citations: 22     Fields:    Translation:Humans
    72. Ni K, Lan G, Chan C, Duan X, Guo N, Veroneau SS, Weichselbaum RR, Lin W. Ultrathin metal-organic layer-mediated radiotherapy-radiodynamic therapy enhances immunotherapy of metastatic cancers. Matter. 2019 Nov 06; 1(5):1331-1353. PMID: 32832885; PMCID: PMC7442115.
      Citations: 24     
    73. Gutiontov SI, Weichselbaum RR. STING (or SRC) Like an ICB: Priming the Immune Response in Pancreatic Cancer. Cancer Res. 2019 08 01; 79(15):3815-3817. PMID: 31371279.
      Citations: 1     Fields:    Translation:AnimalsCells
    74. Pitroda SP, Chmura SJ, Weichselbaum RR. Integration of radiotherapy and immunotherapy for treatment of oligometastases. Lancet Oncol. 2019 08; 20(8):e434-e442. PMID: 31364595.
      Citations: 42     Fields:    Translation:HumansAnimals
    75. Foster CC, Pitroda SP, Weichselbaum RR. Beyond Palliation: The Rationale for Metastasis-Directed Therapy for Metastatic Non-Small Cell Lung Cancer. J Thorac Oncol. 2019 09; 14(9):1510-1512. PMID: 31272814.
      Citations: 3     Fields:    Translation:Humans
    76. Chan C, Guo N, Duan X, Han W, Xue L, Bryan D, Wightman SC, Khodarev NN, Weichselbaum RR, Lin W. Systemic miRNA delivery by nontoxic nanoscale coordination polymers limits epithelial-to-mesenchymal transition and suppresses liver metastases of colorectal cancer. Biomaterials. 2019 07; 210:94-104. PMID: 31060867; PMCID: PMC6579118.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    77. Duan X, Chan C, Han W, Guo N, Weichselbaum RR, Lin W. Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors. Nat Commun. 2019 04 23; 10(1):1899. PMID: 31015397; PMCID: PMC6478897.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    78. Foster CC, Pitroda SP, Weichselbaum RR. Staging the Metastatic Spectrum Through Integration of Clinical and Molecular Features. J Clin Oncol. 2019 05 20; 37(15):1270-1276. PMID: 30939093.
      Citations: 6     Fields:    Translation:Humans
    79. Voce DJ, Bernal GM, Wu L, Crawley CD, Zhang W, Mansour NM, Cahill KE, Szymura SJ, Uppal A, Raleigh DR, Spretz R, Nunez L, Larsen G, Khodarev NN, Weichselbaum RR, Yamini B. Temozolomide Treatment Induces lncRNA MALAT1 in an NF-?B and p53 Codependent Manner in Glioblastoma. Cancer Res. 2019 05 15; 79(10):2536-2548. PMID: 30940658; PMCID: PMC6522287.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    80. Han D, Liu J, Chen C, Dong L, Liu Y, Chang R, Huang X, Liu Y, Wang J, Dougherty U, Bissonnette MB, Shen B, Weichselbaum RR, Xu MM, He C. Author Correction: Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells. Nature. 2019 Apr; 568(7751):E3. PMID: 30911170.
      Citations: 8     Fields:    
    81. Khan MK, Nasti TH, Buchwald ZS, Weichselbaum RR, Kron SJ. Repurposing Drugs for Cancer Radiotherapy: Early Successes and Emerging Opportunities. Cancer J. 2019 Mar/Apr; 25(2):106-115. PMID: 30896532; PMCID: PMC6518392.
      Citations: 5     Fields:    Translation:Humans
    82. Han D, Liu J, Chen C, Dong L, Liu Y, Chang R, Huang X, Liu Y, Wang J, Dougherty U, Bissonnette MB, Shen B, Weichselbaum RR, Xu MM, He C. Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells. Nature. 2019 02; 566(7743):270-274. PMID: 30728504; PMCID: PMC6522227.
      Citations: 378     Fields:    Translation:HumansAnimalsCells
    83. Foster CC, Sher DJ, Rusthoven CG, Verma V, Spiotto MT, Weichselbaum RR, Koshy M. Overall survival according to immunotherapy and radiation treatment for metastatic non-small-cell lung cancer: a National Cancer Database analysis. Radiat Oncol. 2019 Jan 28; 14(1):18. PMID: 30691492; PMCID: PMC6348608.
      Citations: 19     Fields:    Translation:Humans
    84. Huang L, David O, Cabay RJ, Valyi-Nagy K, Macias V, Zhong R, Wenig B, Feldman L, Weichselbaum R, Spiotto MT. Molecular Classification of Lymph Node Metastases Subtypes Predict for Survival in Head and Neck Cancer. Clin Cancer Res. 2019 03 15; 25(6):1795-1808. PMID: 30573692; PMCID: PMC6420850.
      Citations: 11     Fields:    Translation:HumansCells
    85. Oshima G, Poli EC, Bolt MJ, Chlenski A, Forde M, Jutzy JMS, Biyani N, Posner MC, Pitroda SP, Weichselbaum RR, Khodarev NN. DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs. Cancer Res. 2019 02 01; 79(3):650-662. PMID: 30538122.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    86. Foster CC, Weichselbaum RR, Pitroda SP. Oligometastatic prostate cancer: Reality or figment of imagination? Cancer. 2019 02 01; 125(3):340-352. PMID: 30521067; PMCID: PMC6587458.
      Citations: 30     Fields:    Translation:Humans
    87. Ranoa DRE, Widau RC, Mallon S, Parekh AD, Nicolae CM, Huang X, Bolt MJ, Arina A, Parry R, Kron SJ, Moldovan GL, Khodarev NN, Weichselbaum RR. STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability. Cancer Res. 2019 04 01; 79(7):1465-1479. PMID: 30482772; PMCID: PMC6445702.
      Citations: 33     Fields:    Translation:HumansAnimals
    88. Pitroda SP, Khodarev NN, Huang L, Uppal A, Wightman SC, Ganai S, Joseph N, Pitt J, Brown M, Forde M, Mangold K, Xue L, Weber C, Segal JP, Kadri S, Stack ME, Khan S, Paty P, Kaul K, Andrade J, White KP, Talamonti M, Posner MC, Hellman S, Weichselbaum RR. Author Correction: Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis. Nat Commun. 2018 11 13; 9(1):4827. PMID: 30425251; PMCID: PMC6233186.
      Citations:    Fields:    
    89. Epel B, Maggio MC, Barth ED, Miller RC, Pelizzari CA, Krzykawska-Serda M, Sundramoorthy SV, Aydogan B, Weichselbaum RR, Tormyshev VM, Halpern HJ. Oxygen-Guided Radiation Therapy. Int J Radiat Oncol Biol Phys. 2019 03 15; 103(4):977-984. PMID: 30414912; PMCID: PMC6478443.
      Citations: 29     Fields:    Translation:AnimalsCells
    90. Weichselbaum RR. The 46th David A. Karnofsky Memorial Award Lecture: Oligometastasis-From Conception to Treatment. J Clin Oncol. 2018 Nov 10; 36(32):3240-3250. PMID: 30260759.
      Citations: 23     Fields:    
    91. Romero-Calvo I, Weber CR, Ray M, Brown M, Kirby K, Nandi RK, Long TM, Sparrow SM, Ugolkov A, Qiang W, Zhang Y, Brunetti T, Kindler H, Segal JP, Rzhetsky A, Mazar AP, Buschmann MM, Weichselbaum R, Roggin K, White KP. Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors. Mol Cancer Res. 2019 01; 17(1):70-83. PMID: 30171177; PMCID: PMC6647028.
      Citations: 44     Fields:    Translation:HumansAnimals
    92. Hou Y, Liang H, Rao E, Zheng W, Huang X, Deng L, Zhang Y, Yu X, Xu M, Mauceri H, Arina A, Weichselbaum RR, Fu YX. Non-canonical NF-?B Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy. Immunity. 2018 09 18; 49(3):490-503.e4. PMID: 30170810; PMCID: PMC6775781.
      Citations: 86     Fields:    Translation:HumansAnimalsCells
    93. Cai Y, Xue F, Quan C, Qu M, Liu N, Zhang Y, Fleming C, Hu X, Zhang HG, Weichselbaum R, Fu YX, Tieri D, Rouchka EC, Zheng J, Yan J. A Critical Role of the IL-1?-IL-1R Signaling Pathway in Skin Inflammation and Psoriasis Pathogenesis. J Invest Dermatol. 2019 01; 139(1):146-156. PMID: 30120937; PMCID: PMC6392027.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    94. Lu K, Aung T, Guo N, Weichselbaum R, Lin W. Nanoscale Metal-Organic Frameworks for Therapeutic, Imaging, and Sensing Applications. Adv Mater. 2018 Sep; 30(37):e1707634. PMID: 29971835; PMCID: PMC6586248.
      Citations: 61     Fields:    
    95. Wu L, Bernal GM, Cahill KE, Pytel P, Fitzpatrick CA, Mashek H, Weichselbaum RR, Yamini B. BCL3 expression promotes resistance to alkylating chemotherapy in gliomas. Sci Transl Med. 2018 07 04; 10(448). PMID: 29973405; PMCID: PMC6613219.
      Citations: 28     Fields:    Translation:HumansCells
    96. Ni K, Lan G, Chan C, Quigley B, Lu K, Aung T, Guo N, La Riviere P, Weichselbaum RR, Lin W. Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy. Nat Commun. 2018 06 15; 9(1):2351. PMID: 29907739; PMCID: PMC6003951.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    97. Pitroda SP, Khodarev NN, Huang L, Uppal A, Wightman SC, Ganai S, Joseph N, Pitt J, Brown M, Forde M, Mangold K, Xue L, Weber C, Segal JP, Kadri S, Stack ME, Khan S, Paty P, Kaul K, Andrade J, White KP, Talamonti M, Posner MC, Hellman S, Weichselbaum RR. Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis. Nat Commun. 2018 05 04; 9(1):1793. PMID: 29728604; PMCID: PMC5935683.
      Citations: 90     Fields:    Translation:Humans
    98. Murley JS, Arbiser JL, Weichselbaum RR, Grdina DJ. ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response. Free Radic Biol Med. 2018 08 01; 123:39-52. PMID: 29660403.
      Citations: 9     Fields:    Translation:HumansCells
    99. Hong JC, Ayala-Peacock DN, Lee J, Blackstock AW, Okunieff P, Sung MW, Weichselbaum RR, Kao J, Urbanic JJ, Milano MT, Chmura SJ, Salama JK. Classification for long-term survival in oligometastatic patients treated with ablative radiotherapy: A multi-institutional pooled analysis. PLoS One. 2018; 13(4):e0195149. PMID: 29649281; PMCID: PMC5896920.
      Citations: 38     Fields:    Translation:Humans
    100. Chmura SJ, Connell PP, Weichselbaum RR. Retuning the Radio in Radiobiology. J Natl Cancer Inst. 2018 04 01; 110(4):325-326. PMID: 29126281; PMCID: PMC6927860.
      Citations:    Fields:    
    101. Lu K, He C, Guo N, Chan C, Ni K, Lan G, Tang H, Pelizzari C, Fu YX, Spiotto MT, Weichselbaum RR, Lin W. Low-dose X-ray radiotherapy-radiodynamic therapy via nanoscale metal-organic frameworks enhances checkpoint blockade immunotherapy. Nat Biomed Eng. 2018 08; 2(8):600-610. PMID: 31015630.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    102. Pitroda SP, Stack ME, Liu GF, Song SS, Chen L, Liang H, Parekh AD, Huang X, Roach P, Posner MC, Weichselbaum RR, Khodarev NN. JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non-small Cell Lung Cancers. Mol Cancer Ther. 2018 04; 17(4):732-739. PMID: 29467274.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    103. Luke JJ, Lemons JM, Karrison TG, Pitroda SP, Melotek JM, Zha Y, Al-Hallaq HA, Arina A, Khodarev NN, Janisch L, Chang P, Patel JD, Fleming GF, Moroney J, Sharma MR, White JR, Ratain MJ, Gajewski TF, Weichselbaum RR, Chmura SJ. Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors. J Clin Oncol. 2018 06 01; 36(16):1611-1618. PMID: 29437535; PMCID: PMC5978468.
      Citations: 217     Fields:    Translation:HumansCTClinical Trials
    104. Liang H, Deng L, Hou Y, Meng X, Huang X, Rao E, Zheng W, Mauceri H, Mack M, Xu M, Fu YX, Weichselbaum RR. Host STING-dependent MDSC mobilization drives extrinsic radiation resistance. Nat Commun. 2017 11 23; 8(1):1736. PMID: 29170400; PMCID: PMC5701019.
      Citations: 160     Fields:    Translation:HumansAnimalsCells
    105. Patel P, Oh AL, Koshy M, Sweiss K, Saraf SL, Quigley JG, Khan I, Mahmud N, Hacker E, Ozer H, Peace DJ, Weichselbaum RR, Aydogan B, Rondelli D. A phase 1 trial of autologous stem cell transplantation conditioned with melphalan 200?mg/m2 and total marrow irradiation (TMI) in patients with relapsed/refractory multiple myeloma. Leuk Lymphoma. 2018 07; 59(7):1666-1671. PMID: 29065747.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    106. Efimova EV, Ricco N, Labay E, Mauceri HJ, Flor AC, Ramamurthy A, Sutton HG, Weichselbaum RR, Kron SJ. HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation. Mol Cancer Ther. 2018 02; 17(2):407-418. PMID: 29030460; PMCID: PMC5805623.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    107. Spiotto MT, Jefferson GD, Wenig B, Markiewicz MR, Weichselbaum RR, Koshy M. Survival outcomes for postoperative chemoradiation in intermediate-risk oral tongue cancers. Head Neck. 2017 12; 39(12):2537-2548. PMID: 28960621.
      Citations: 3     Fields:    Translation:Humans
    108. Koshy M, Sher DJ, Spiotto M, Husain Z, Engelhard H, Slavin K, Nicholas MK, Weichselbaum RR, Rusthoven C. Association between hospital volume and receipt of treatment and survival in patients with glioblastoma. J Neurooncol. 2017 Dec; 135(3):529-534. PMID: 28836140.
      Citations: 9     Fields:    Translation:Humans
    109. Murley JS, Miller RC, Weichselbaum RR, Grdina DJ. TP53 Mutational Status and ROS Effect the Expression of the Survivin-Associated Radio-Adaptive Response. Radiat Res. 2017 11; 188(5):579-590. PMID: 28813624; PMCID: PMC5705057.
      Citations: 5     Fields:    Translation:HumansCells
    110. Xu MM, Pu Y, Han D, Shi Y, Cao X, Liang H, Chen X, Li XD, Deng L, Chen ZJ, Weichselbaum RR, Fu YX. Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein a Signaling. Immunity. 2017 08 15; 47(2):363-373.e5. PMID: 28801234; PMCID: PMC5564225.
      Citations: 107     Fields:    Translation:HumansAnimalsCells
    111. Chmura SJ, Weichselbaum RR. Rhythmic radiotherapy beats down TGF-?. Cell Cycle. 2017 08 03; 16(15):1391. PMID: 28723240; PMCID: PMC5553403.
      Citations: 1     Fields:    Translation:Cells
    112. Chmura SJ, Weichselbaum RR. Rhythmic radiotherapy beats down TGF-ß. Cell Cycle. 2017 Aug 03; 16(15):1391. PMID: 28727497.
      Citations:    
    113. Spiotto MT, Jefferson G, Wenig B, Markiewicz M, Weichselbaum RR, Koshy M. Differences in Survival With Surgery and Postoperative Radiotherapy Compared With Definitive Chemoradiotherapy for Oral Cavity Cancer: A National Cancer Database Analysis. JAMA Otolaryngol Head Neck Surg. 2017 07 01; 143(7):691-699. PMID: 28426848; PMCID: PMC5547927.
      Citations: 18     Fields:    Translation:Humans
    114. Zhang Y, Kim TJ, Wroblewska JA, Tesic V, Upadhyay V, Weichselbaum RR, Tumanov AV, Tang H, Guo X, Tang H, Fu YX. Type 3 innate lymphoid cell-derived lymphotoxin prevents microbiota-dependent inflammation. Cell Mol Immunol. 2018 07; 15(7):697-709. PMID: 28579615; PMCID: PMC6123485.
      Citations: 8     Fields:    Translation:AnimalsCells
    115. Oshima G, Guo N, He C, Stack ME, Poon C, Uppal A, Wightman SC, Parekh A, Skowron KB, Posner MC, Lin W, Khodarev NN, Weichselbaum RR. In?Vivo Delivery and Therapeutic Effects of a MicroRNA on Colorectal Liver Metastases. Mol Ther. 2017 07 05; 25(7):1588-1595. PMID: 28457664; PMCID: PMC5498809.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    116. Kammertoens T, Friese C, Arina A, Idel C, Briesemeister D, Rothe M, Ivanov A, Szymborska A, Patone G, Kunz S, Sommermeyer D, Engels B, Leisegang M, Textor A, Fehling HJ, Fruttiger M, Lohoff M, Herrmann A, Yu H, Weichselbaum R, Uckert W, H?bner N, Gerhardt H, Beule D, Schreiber H, Blankenstein T. Tumour ischaemia by interferon-? resembles physiological blood vessel regression. Nature. 2017 05 04; 545(7652):98-102. PMID: 28445461; PMCID: PMC5567674.
      Citations: 116     Fields:    Translation:AnimalsCells
    117. Pitroda SP, Bao R, Andrade J, Weichselbaum RR, Connell PP. Low Recombination Proficiency Score (RPS) Predicts Heightened Sensitivity to DNA-Damaging Chemotherapy in Breast Cancer. Clin Cancer Res. 2017 Aug 01; 23(15):4493-4500. PMID: 28341751; PMCID: PMC5540755.
      Citations: 8     Fields:    Translation:HumansCells
    118. Shukla V, Dalela M, Vij M, Weichselbaum R, Kharbanda S, Ganguli M, Kufe D, Singh H. Systemic delivery of the tumor necrosis factor gene to tumors by a novel dual DNA-nanocomplex in a nanoparticle system. Nanomedicine. 2017 07; 13(5):1833-1839. PMID: 28343015; PMCID: PMC5706451.
      Citations: 3     Fields:    Translation:Humans
    119. Rolle CE, Tan YC, Seiwert TY, Vora S, Kanteti R, Hasina R, Carey GB, Surati M, Weichselbaum RR, Lingen MW, Vokes EE, Salgia R. Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma. Oncotarget. 2017 Mar 21; 8(12):18726-18734. PMID: 27244893; PMCID: PMC5386642.
      Citations: 2     Fields:    Translation:Humans
    120. Qadir AS, Ceppi P, Brockway S, Law C, Mu L, Khodarev NN, Kim J, Zhao JC, Putzbach W, Murmann AE, Chen Z, Chen W, Liu X, Salomon AR, Liu H, Weichselbaum RR, Yu J, Peter ME. CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response. Cell Rep. 2017 03 07; 18(10):2373-2386. PMID: 28273453; PMCID: PMC5474321.
      Citations: 49     Fields:    Translation:HumansCells
    121. Weichselbaum RR, Liang H, Deng L, Fu YX. Radiotherapy and immunotherapy: a beneficial liaison? Nat Rev Clin Oncol. 2017 Jun; 14(6):365-379. PMID: 28094262.
      Citations: 348     Fields:    Translation:Humans
    122. Arina A, Karrison T, Galka E, Schreiber K, Weichselbaum RR, Schreiber H. Transfer of Allogeneic CD4+ T Cells Rescues CD8+ T Cells in Anti-PD-L1-Resistant Tumors Leading to Tumor Eradication. Cancer Immunol Res. 2017 02; 5(2):127-136. PMID: 28077434; PMCID: PMC5354300.
      Citations: 9     Fields:    Translation:AnimalsCells
    123. Duan X, Chan C, Guo N, Han W, Weichselbaum RR, Lin W. Photodynamic Therapy Mediated by Nontoxic Core-Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer. J Am Chem Soc. 2016 12 28; 138(51):16686-16695. PMID: 27976881; PMCID: PMC5667903.
      Citations: 107     Fields:    Translation:HumansAnimalsCells
    124. Meng Y, Mauceri HJ, Khodarev NN, Darga TE, Pitroda SP, Beckett MA, Kufe DW, Weichselbaum RR. Ad.Egr-TNF and Local Ionizing Radiation Suppress Metastases by Interferon-ß-Dependent Activation of Antigen-specific CD8+ T Cells. Mol Ther. 2010 May; 18(5):912-920. PMID: 28178556.
      Citations:    
    125. Oshima G, Stack ME, Wightman SC, Bryan D, Poli E, Xue L, Skowron KB, Uppal A, Pitroda SP, Huang X, Posner MC, Hellman S, Weichselbaum RR, Khodarev NN. Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones. J Vis Exp. 2016 11 30; (117). PMID: 27929457; PMCID: PMC6145586.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    126. Smith GL, Ganz PA, Bekelman JE, Chmura SJ, Dignam JJ, Efstathiou JA, Jagsi R, Johnstone PA, Steinberg ML, Williams SB, Yu JB, Zietman AL, Weichselbaum RR, Tina Shih YC. Promoting the Appropriate Use of Advanced Radiation Technologies in Oncology: Summary of a National Cancer Policy Forum Workshop. Int J Radiat Oncol Biol Phys. 2017 03 01; 97(3):450-461. PMID: 28011046; PMCID: PMC6044722.
      Citations: 12     Fields:    Translation:Humans
    127. Skowron KB, Pitroda SP, Namm JP, Balogun O, Beckett MA, Zenner ML, Fayanju O, Huang X, Fernandez C, Zheng W, Qiao G, Chin R, Kron SJ, Khodarev NN, Posner MC, Steinberg GD, Weichselbaum RR. Basal Tumor Cell Isolation and Patient-Derived Xenograft Engraftment Identify High-Risk Clinical Bladder Cancers. Sci Rep. 2016 10 24; 6:35854. PMID: 27775025; PMCID: PMC5075783.
      Citations: 7     Fields:    Translation:HumansAnimals
    128. Spiotto M, Fu YX, Weichselbaum RR. The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications. Sci Immunol. 2016 Sep; 1(3). PMID: 28018989; PMCID: PMC5171206.
      Citations: 77     Fields:    
    129. Lu K, He C, Guo N, Chan C, Ni K, Weichselbaum RR, Lin W. Chlorin-Based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy. J Am Chem Soc. 2016 09 28; 138(38):12502-10. PMID: 27575718; PMCID: PMC5673483.
      Citations: 100     Fields:    Translation:AnimalsCells
    130. Appelbe OK, Zhang Q, Pelizzari CA, Weichselbaum RR, Kron SJ. Image-Guided Radiotherapy Targets Macromolecules through Altering the Tumor Microenvironment. Mol Pharm. 2016 10 03; 13(10):3457-3467. PMID: 27560921; PMCID: PMC5103304.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    131. He C, Duan X, Guo N, Chan C, Poon C, Weichselbaum RR, Lin W. Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy. Nat Commun. 2016 08 17; 7:12499. PMID: 27530650; PMCID: PMC4992065.
      Citations: 182     Fields:    Translation:AnimalsCells
    132. Michelle Xu M, Pu Y, Weichselbaum RR, Fu YX. Integrating conventional and antibody-based targeted anticancer treatment into immunotherapy. Oncogene. 2017 02 02; 36(5):585-592. PMID: 27425593; PMCID: PMC5243926.
      Citations: 10     Fields:    Translation:HumansAnimals
    133. Miller RC, Murley JS, Rademaker AW, Woloschak GE, Li JJ, Weichselbaum RR, Grdina DJ. Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity. Free Radic Biol Med. 2016 10; 99:110-119. PMID: 27427516; PMCID: PMC6764831.
      Citations: 4     Fields:    Translation:AnimalsCells
    134. Zheng W, Skowron KB, Namm JP, Burnette B, Fernandez C, Arina A, Liang H, Spiotto MT, Posner MC, Fu YX, Weichselbaum RR. Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance. Oncotarget. 2016 Jul 12; 7(28):43039-43051. PMID: 27343548; PMCID: PMC5190006.
      Citations: 38     Fields:    Translation:AnimalsCellsPHPublic Health
    135. Arina A, Idel C, Hyjek EM, Alegre ML, Wang Y, Bindokas VP, Weichselbaum RR, Schreiber H. Tumor-associated fibroblasts predominantly come from local and not circulating precursors. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):7551-6. PMID: 27317748; PMCID: PMC4941507.
      Citations: 80     Fields:    Translation:AnimalsCells
    136. Labay E, Mauceri HJ, Efimova EV, Flor AC, Sutton HG, Kron SJ, Weichselbaum RR. Repurposing cephalosporin antibiotics as pro-senescent radiosensitizers. Oncotarget. 2016 Jun 07; 7(23):33919-33. PMID: 27129153; PMCID: PMC5085128.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    137. Liauw SL, Reddy AV, Weichselbaum RR, Smith ND, Steinberg GD. In Reply to Zaghloul. Int J Radiat Oncol Biol Phys. 2016 06 01; 95(2):855. PMID: 27131088.
      Citations:    Fields:    
    138. Wang T, Mathew B, Wu X, Shimizu Y, Rizzo AN, Dudek SM, Weichselbaum RR, Jacobson JR, Hecker L, Garcia JG. Nonmuscle myosin light chain kinase activity modulates radiation-induced lung injury. Pulm Circ. 2016 Jun; 6(2):234-9. PMID: 27252850; PMCID: PMC4869928.
      Citations: 7     
    139. Wong AC, Watson SP, Pitroda SP, Son CH, Das LC, Stack ME, Uppal A, Oshima G, Khodarev NN, Salama JK, Weichselbaum RR, Chmura SJ. Clinical and molecular markers of long-term survival after oligometastasis-directed stereotactic body radiotherapy (SBRT). Cancer. 2016 07 15; 122(14):2242-50. PMID: 27206146.
      Citations: 41     Fields:    Translation:Humans
    140. Drazer MW, Salama JK, Hahn OM, Weichselbaum RR, Chmura SJ. Stereotactic body radiotherapy for oligometastatic breast cancer: a new standard of care, or a medical reversal in waiting? Expert Rev Anticancer Ther. 2016 Jun; 16(6):625-32. PMID: 27078719.
      Citations: 1     Fields:    Translation:Humans
    141. Ranoa DR, Parekh AD, Pitroda SP, Huang X, Darga T, Wong AC, Huang L, Andrade J, Staley JP, Satoh T, Akira S, Weichselbaum RR, Khodarev NN. Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs. Oncotarget. 2016 May 03; 7(18):26496-515. PMID: 27034163; PMCID: PMC5041995.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    142. Koshy M, Malik R, Mahmood U, Husain Z, Weichselbaum RR, Sher DJ. Response. J Natl Cancer Inst. 2016 Mar; 108(3). PMID: 26744479.
      Citations:    Fields:    Translation:Humans
    143. Leisegang M, Engels B, Schreiber K, Yew PY, Kiyotani K, Idel C, Arina A, Duraiswamy J, Weichselbaum RR, Uckert W, Nakamura Y, Schreiber H. Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation. Clin Cancer Res. 2016 06 01; 22(11):2734-43. PMID: 26667491; PMCID: PMC4891260.
      Citations: 39     Fields:    Translation:AnimalsCells
    144. Reddy AV, Pariser JJ, Pearce SM, Weichselbaum RR, Smith ND, Steinberg GD, Liauw SL. Patterns of Failure After Radical Cystectomy for pT3-4 Bladder Cancer: Implications for Adjuvant Radiation Therapy. Int J Radiat Oncol Biol Phys. 2016 Apr 01; 94(5):1031-9. PMID: 27026309.
      Citations: 10     Fields:    Translation:Humans
    145. Efimova EV, Takahashi S, Shamsi NA, Wu D, Labay E, Ulanovskaya OA, Weichselbaum RR, Kozmin SA, Kron SJ. Linking Cancer Metabolism to DNA Repair and Accelerated Senescence. Mol Cancer Res. 2016 Feb; 14(2):173-84. PMID: 26538285; PMCID: PMC4755886.
      Citations: 29     Fields:    Translation:HumansCells
    146. Mathew B, Takekoshi D, Sammani S, Epshtein Y, Sharma R, Smith BD, Mitra S, Desai AA, Weichselbaum RR, Garcia JG, Jacobson JR. Role of GADD45a in murine models of radiation- and bleomycin-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15; 309(12):L1420-9. PMID: 26498248; PMCID: PMC4683317.
      Citations: 7     Fields:    Translation:AnimalsCells
    147. Bronova I, Smith B, Aydogan B, Weichselbaum RR, Vemuri K, Erdelyi K, Makriyannis A, Pacher P, Berdyshev EV. Protection from Radiation-Induced Pulmonary Fibrosis by Peripheral Targeting of Cannabinoid Receptor-1. Am J Respir Cell Mol Biol. 2015 Oct; 53(4):555-62. PMID: 26426981; PMCID: PMC4742897.
      Citations: 15     Fields:    Translation:AnimalsPHPublic Health
    148. Koshy M, Malik R, Mahmood U, Husain Z, Weichselbaum RR, Sher DJ. Prevalence and Predictors of Inappropriate Delivery of Palliative Thoracic Radiotherapy for Metastatic Lung Cancer. J Natl Cancer Inst. 2015 Dec; 107(12):djv278. PMID: 26424779; PMCID: PMC4862415.
      Citations: 5     Fields:    Translation:Humans
    149. Deng L, Liang H, Fu S, Weichselbaum RR, Fu YX. From DNA Damage to Nucleic Acid Sensing: A Strategy to Enhance Radiation Therapy. Clin Cancer Res. 2016 Jan 01; 22(1):20-5. PMID: 26362999.
      Citations: 27     Fields:    Translation:HumansCells
    150. McCormick S, He Q, Stern J, Khodarev N, Weichselbaum R, Skelly CL. Evidence for the Use of Multiple Mechanisms by Herpes Simplex Virus-1 R7020 to Inhibit Intimal Hyperplasia. PLoS One. 2015; 10(7):e0130264. PMID: 26132411; PMCID: PMC4488439.
      Citations:    Fields:    Translation:HumansAnimalsCells
    151. Oshima G, Wightman SC, Uppal A, Stack ME, Pitroda SP, Oskvarek JJ, Huang X, Posner MC, Hellman S, Weichselbaum RR, Khodarev NN. Imaging of tumor clones with differential liver colonization. Sci Rep. 2015 Jun 22; 5:10946. PMID: 26094901; PMCID: PMC4476146.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    152. Binder DC, Fu YX, Weichselbaum RR. Radiotherapy and immune checkpoint blockade: potential interactions and future directions. Trends Mol Med. 2015 Aug; 21(8):463-5. PMID: 26091823.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    153. Wightman SC, Uppal A, Pitroda SP, Ganai S, Burnette B, Stack M, Oshima G, Khan S, Huang X, Posner MC, Weichselbaum RR, Khodarev NN. Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome. Br J Cancer. 2015 Jul 14; 113(2):327-35. PMID: 26042934; PMCID: PMC4506383.
      Citations: 61     Fields:    Translation:AnimalsCells
    154. He C, Chan C, Weichselbaum RR, Fleming GF, Yamada SD, Lin W. Nanomedicine for Combination Therapy of Cancer. EBioMedicine. 2015 May; 2(5):366-7. PMID: 26137577; PMCID: PMC4486458.
      Citations: 5     Fields:    Translation:HumansAnimals
    155. Mansour NM, Bernal GM, Wu L, Crawley CD, Cahill KE, Voce DJ, Balyasnikova IV, Zhang W, Spretz R, Nunez L, Larsen GF, Weichselbaum RR, Yamini B. Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide. Cancer Res. 2015 May 15; 75(10):2039-48. PMID: 25808868; PMCID: PMC4433625.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    156. Mason JM, Dusad K, Wright WD, Grubb J, Budke B, Heyer WD, Connell PP, Weichselbaum RR, Bishop DK. RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells. Nucleic Acids Res. 2015 Mar 31; 43(6):3180-96. PMID: 25765654; PMCID: PMC4381078.
      Citations: 32     Fields:    Translation:HumansCells
    157. Khodarev NN, Pitroda SP, Weichselbaum RR. microRNAs and oligometastasis. Aging (Albany NY). 2015 Mar; 7(3):146-7. PMID: 25868522; PMCID: PMC4394724.
      Citations: 4     Fields:    Translation:Humans
    158. Uppal A, Wightman SC, Mallon S, Oshima G, Pitroda SP, Zhang Q, Huang X, Darga TE, Huang L, Andrade J, Liu H, Ferguson MK, Greene GL, Posner MC, Hellman S, Khodarev NN, Weichselbaum RR. 14q32-encoded microRNAs mediate an oligometastatic phenotype. Oncotarget. 2015 Feb 28; 6(6):3540-52. PMID: 25686838; PMCID: PMC4414135.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    159. Takahashi H, Jin C, Rajabi H, Pitroda S, Alam M, Ahmad R, Raina D, Hasegawa M, Suzuki Y, Tagde A, Bronson RT, Weichselbaum R, Kufe D. MUC1-C activates the TAK1 inflammatory pathway in colon cancer. Oncogene. 2015 Oct 01; 34(40):5187-97. PMID: 25659581; PMCID: PMC4530107.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    160. Koshy M, Malik R, Weichselbaum RR, Sher DJ. Increasing radiation therapy dose is associated with improved survival in patients undergoing stereotactic body radiation therapy for stage I non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2015 Feb 01; 91(2):344-50. PMID: 25636759.
      Citations: 40     Fields:    Translation:Humans
    161. Koshy M, Malik R, Spiotto M, Mahmood U, Weichselbaum R, Sher D. Disparities in treatment of patients with inoperable stage I non-small cell lung cancer: a population-based analysis. J Thorac Oncol. 2015 Feb; 10(2):264-71. PMID: 25371079; PMCID: PMC4807970.
      Citations: 10     Fields:    Translation:Humans
    162. Crawley CD, Kang S, Bernal GM, Wahlstrom JS, Voce DJ, Cahill KE, Garofalo A, Raleigh DR, Weichselbaum RR, Yamini B. S-phase-dependent p50/NF-?B1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability. Cell Cycle. 2015; 14(4):566-76. PMID: 25590437; PMCID: PMC4614791.
      Citations: 10     Fields:    Translation:HumansCells
    163. Burnette B, Weichselbaum RR. The immunology of ablative radiation. Semin Radiat Oncol. 2015 Jan; 25(1):40-5. PMID: 25481265.
      Citations: 14     Fields:    Translation:HumansAnimals
    164. Keck MK, Zuo Z, Khattri A, Stricker TP, Brown CD, Imanguli M, Rieke D, Endhardt K, Fang P, Br?gelmann J, DeBoer R, El-Dinali M, Aktolga S, Lei Z, Tan P, Rozen SG, Salgia R, Weichselbaum RR, Lingen MW, Story MD, Ang KK, Cohen EE, White KP, Vokes EE, Seiwert TY. Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes. Clin Cancer Res. 2015 Feb 15; 21(4):870-81. PMID: 25492084.
      Citations: 158     Fields:    Translation:HumansCells
    165. Sur MD, In H, Sharpe SM, Baker MS, Weichselbaum RR, Talamonti MS, Posner MC. Defining the Benefit of Adjuvant Therapy Following Resection for Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2015 Jul; 22(7):2209-17. PMID: 25476031.
      Citations: 26     Fields:    Translation:Humans
    166. Deng L, Liang H, Xu M, Yang X, Burnette B, Arina A, Li XD, Mauceri H, Beckett M, Darga T, Huang X, Gajewski TF, Chen ZJ, Fu YX, Weichselbaum RR. STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors. Immunity. 2014 Nov 20; 41(5):843-52. PMID: 25517616; PMCID: PMC5155593.
      Citations: 758     Fields:    Translation:AnimalsCells
    167. Bernal GM, Wahlstrom JS, Crawley CD, Cahill KE, Pytel P, Liang H, Kang S, Weichselbaum RR, Yamini B. Loss of Nfkb1 leads to early onset aging. Aging (Albany NY). 2014 Nov; 6(11):931-43. PMID: 25553648; PMCID: PMC4276787.
      Citations: 43     Fields:    Translation:AnimalsCells
    168. Patel P, Aydogan B, Koshy M, Mahmud D, Oh A, Saraf SL, Quigley JG, Khan I, Sweiss K, Mahmud N, Peace DJ, DeMasi V, Awan AM, Weichselbaum RR, Rondelli D. Combination of linear accelerator-based intensity-modulated total marrow irradiation and myeloablative fludarabine/busulfan: a phase I study. Biol Blood Marrow Transplant. 2014 Dec; 20(12):2034-41. PMID: 25234438.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    169. Seiwert TY, Zuo Z, Keck MK, Khattri A, Pedamallu CS, Stricker T, Brown C, Pugh TJ, Stojanov P, Cho J, Lawrence MS, Getz G, Br?gelmann J, DeBoer R, Weichselbaum RR, Langerman A, Portugal L, Blair E, Stenson K, Lingen MW, Cohen EE, Vokes EE, White KP, Hammerman PS. Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas. Clin Cancer Res. 2015 Feb 01; 21(3):632-41. PMID: 25056374; PMCID: PMC4305034.
      Citations: 285     Fields:    Translation:HumansCells
    170. Voce DJ, Schmitt AM, Uppal A, McNerney ME, Bernal GM, Cahill KE, Wahlstrom JS, Nassiri A, Yu X, Crawley CD, White KP, Onel K, Weichselbaum RR, Yamini B. Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor. Oncogene. 2015 May 21; 34(21):2807-13. PMID: 25043302; PMCID: PMC4302074.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    171. Seiwert TY, Wang X, Heitmann J, Villegas-Bergazzi V, Sprott K, Finn S, O'Regan E, Farrow AD, Weichselbaum RR, Lingen MW, Cohen EE, Stenson K, Weaver DT, Vokes EE. DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer. PLoS One. 2014; 9(7):e102112. PMID: 25019640; PMCID: PMC4096922.
      Citations: 6     Fields:    Translation:HumansCells
    172. Heitmann J, Geeleher P, Zuo Z, Weichselbaum RR, Vokes EE, Fetscher S, Seiwert TY. Poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer. Oral Oncol. 2014 Sep; 50(9):825-31. PMID: 25017803.
      Citations: 4     Fields:    Translation:HumansCells
    173. Uppal A, Ferguson MK, Posner MC, Hellman S, Khodarev NN, Weichselbaum RR. Towards a molecular basis of oligometastatic disease: potential role of micro-RNAs. Clin Exp Metastasis. 2014 Aug; 31(6):735-48. PMID: 24968866; PMCID: PMC4138440.
      Citations: 34     Fields:    Translation:Humans
    174. Palma DA, Salama JK, Lo SS, Senan S, Treasure T, Govindan R, Weichselbaum R. The oligometastatic state - separating truth from wishful thinking. Nat Rev Clin Oncol. 2014 09; 11(9):549-57. PMID: 24958182.
      Citations: 91     Fields:    Translation:Humans
    175. Koshy M, Malik R, Sher DJ, Spiotto M, Mahmood U, Aydogan B, Weichselbaum RR. The effect of radiotherapy dose on survival in stage III non-small-cell lung cancer patients undergoing definitive chemoradiotherapy. Clin Lung Cancer. 2014 Sep; 15(5):365-71. PMID: 24984565.
      Citations: 5     Fields:    Translation:Humans
    176. Mason JM, Logan HL, Budke B, Wu M, Pawlowski M, Weichselbaum RR, Kozikowski AP, Bishop DK, Connell PP. The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors. Cancer Res. 2014 Jul 01; 74(13):3546-55. PMID: 24753542; PMCID: PMC4079730.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    177. Uppal A, Wightman SC, Ganai S, Weichselbaum RR, An G. Investigation of the essential role of platelet-tumor cell interactions in metastasis progression using an agent-based model. Theor Biol Med Model. 2014 Apr 12; 11:17. PMID: 24725600; PMCID: PMC4022382.
      Citations: 21     Fields:    Translation:HumansCells
    178. Spiotto MT, Weichselbaum RR. Comparison of 3D confromal radiotherapy and intensity modulated radiotherapy with or without simultaneous integrated boost during concurrent chemoradiation for locally advanced head and neck cancers. PLoS One. 2014; 9(4):e94456. PMID: 24714187; PMCID: PMC3979891.
      Citations: 21     Fields:    Translation:Humans
    179. Pitroda SP, Pashtan IM, Logan HL, Budke B, Darga TE, Weichselbaum RR, Connell PP. DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy. Sci Transl Med. 2014 Mar 26; 6(229):229ra42. PMID: 24670686; PMCID: PMC4889008.
      Citations: 44     Fields:    Translation:HumansCells
    180. Uppal A, Weichselbaum RR, Posner MC. Optimizing management of colorectal hepatic metastases: now and in the future. Eur J Surg Oncol. 2014 Sep; 40(9):1033-5. PMID: 24703655.
      Citations: 1     Fields:    Translation:Humans
    181. Markert JM, Razdan SN, Kuo HC, Cantor A, Knoll A, Karrasch M, Nabors LB, Markiewicz M, Agee BS, Coleman JM, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Weichselbaum RR, Fiveash JB, Gillespie GY. A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses. Mol Ther. 2014 May; 22(5):1048-55. PMID: 24572293; PMCID: PMC4015243.
      Citations: 127     Fields:    Translation:HumansCellsCTClinical Trials
    182. Tye K, Engelhard HH, Slavin KV, Nicholas MK, Chmura SJ, Kwok Y, Ho DS, Weichselbaum RR, Koshy M. An analysis of radiation necrosis of the central nervous system treated with bevacizumab. J Neurooncol. 2014 Apr; 117(2):321-7. PMID: 24504500.
      Citations: 31     Fields:    Translation:HumansPHPublic Health
    183. Widau RC, Parekh AD, Ranck MC, Golden DW, Kumar KA, Sood RF, Pitroda SP, Liao Z, Huang X, Darga TE, Xu D, Huang L, Andrade J, Roizman B, Weichselbaum RR, Khodarev NN. RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):E484-91. PMID: 24434553; PMCID: PMC3910628.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    184. Yang X, Zhang X, Fu ML, Weichselbaum RR, Gajewski TF, Guo Y, Fu YX. Targeting the tumor microenvironment with interferon-? bridges innate and adaptive immune responses. Cancer Cell. 2014 Jan 13; 25(1):37-48. PMID: 24434209; PMCID: PMC3927846.
      Citations: 132     Fields:    Translation:AnimalsCells
    185. Chmura SJ, Salama JK, Weichselbaum RR. Stereotactic radiotherapy for pulmonary metastases. Semin Thorac Cardiovasc Surg. 2013; 25(4):292-9. PMID: 24673958.
      Citations: 3     Fields:    Translation:Humans
    186. Deng L, Liang H, Burnette B, Beckett M, Darga T, Weichselbaum RR, Fu YX. Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J Clin Invest. 2014 Feb; 124(2):687-95. PMID: 24382348; PMCID: PMC3904601.
      Citations: 819     Fields:    Translation:AnimalsCells
    187. Ranck MC, Abundo R, Jefferson G, Kolokythas A, Wenig BL, Weichselbaum RR, Spiotto MT. Effect of postradiotherapy neck dissection on nonregional disease sites. JAMA Otolaryngol Head Neck Surg. 2014 Jan; 140(1):12-21. PMID: 24263403; PMCID: PMC4662541.
      Citations: 1     Fields:    Translation:Humans
    188. Ranck MC, Golden DW, Corbin KS, Hasselle MD, Liauw SL, Stadler WM, Hahn OM, Weichselbaum RR, Salama JK. Stereotactic body radiotherapy for the treatment of oligometastatic renal cell carcinoma. Am J Clin Oncol. 2013 Dec; 36(6):589-95. PMID: 22868242.
      Citations: 30     Fields:    Translation:HumansCTClinical Trials
    189. Connell PP, Weichselbaum RR. Small molecule derived from a natural product that mitigates radiation injury. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18355-6. PMID: 24187150; PMCID: PMC3831980.
      Citations: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    190. Zakeri K, MacEwan I, Vazirnia A, Cohen EE, Spiotto MT, Haraf DJ, Vokes EE, Weichselbaum RR, Mell LK. Race and competing mortality in advanced head and neck cancer. Oral Oncol. 2014 Jan; 50(1):40-4. PMID: 24134948.
      Citations: 9     Fields:    Translation:Humans
    191. Liu GF, Ranck MC, Solanki AA, Cao H, Kolokythas A, Wenig BL, Chen L, Ard S, Weichselbaum RR, Halpern H, Spiotto MT. Racial parities in outcomes after radiotherapy for head and neck cancer. Cancer. 2014 Jan 15; 120(2):244-52. PMID: 24122486; PMCID: PMC4662546.
      Citations: 5     Fields:    Translation:Humans
    192. Burnette B, Weichselbaum RR. Radiation as an immune modulator. Semin Radiat Oncol. 2013 Oct; 23(4):273-80. PMID: 24012341.
      Citations: 75     Fields:    Translation:Humans
    193. Herman LC, Chen L, Garnett A, Feldman LE, Smith B, Weichselbaum RR, Spiotto MT. Comparison of carboplatin-paclitaxel to docetaxel-cisplatin-5-flurouracil induction chemotherapy followed by concurrent chemoradiation for locally advanced head and neck cancer. Oral Oncol. 2014 Jan; 50(1):52-8. PMID: 24055193.
      Citations: 7     Fields:    Translation:Humans
    194. Stancevic B, Varda-Bloom N, Cheng J, Fuller JD, Rotolo JA, Garc?a-Barros M, Feldman R, Rao S, Weichselbaum RR, Harats D, Haimovitz-Friedman A, Fuks Z, Sadelain M, Kolesnick R. Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure. PLoS One. 2013; 8(8):e69025. PMID: 23936314; PMCID: PMC3732255.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    195. Mathew B, Jacobson JR, Siegler JH, Moitra J, Blasco M, Xie L, Unzueta C, Zhou T, Evenoski C, Al-Sakka M, Sharma R, Huey B, Bulent A, Smith B, Jayaraman S, Reddy NM, Reddy SP, Fingerle-Rowson G, Bucala R, Dudek SM, Natarajan V, Weichselbaum RR, Garcia JG. Role of migratory inhibition factor in age-related susceptibility to radiation lung injury via NF-E2-related factor-2 and antioxidant regulation. Am J Respir Cell Mol Biol. 2013 Aug; 49(2):269-78. PMID: 23526214; PMCID: PMC3824032.
      Citations: 26     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    196. Bernal GM, LaRiviere MJ, Mansour N, Pytel P, Cahill KE, Voce DJ, Kang S, Spretz R, Welp U, Noriega SE, Nunez L, Larsen GF, Weichselbaum RR, Yamini B. Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma. Nanomedicine. 2014 Jan; 10(1):149-57. PMID: 23891990; PMCID: PMC3871979.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    197. Elas M, Magwood JM, Butler B, Li C, Wardak R, DeVries R, Barth ED, Epel B, Rubinstein S, Pelizzari CA, Weichselbaum RR, Halpern HJ. EPR oxygen images predict tumor control by a 50% tumor control radiation dose. Cancer Res. 2013 Sep 01; 73(17):5328-35. PMID: 23861469; PMCID: PMC3913470.
      Citations: 27     Fields:    Translation:AnimalsCells
    198. Liang H, Deng L, Burnette B, Weichselbaum RR, Fu YX. Radiation-induced tumor dormancy reflects an equilibrium between the proliferation and T lymphocyte-mediated death of malignant cells. Oncoimmunology. 2013 Sep 01; 2(9):e25668. PMID: 24319637; PMCID: PMC3850275.
      Citations: 9     Fields:    
    199. Koshy M, Fedewa SA, Malik R, Ferguson MK, Vigneswaran WT, Feldman L, Howard A, Abdelhady K, Weichselbaum RR, Virgo KS. Improved survival associated with neoadjuvant chemoradiation in patients with clinical stage IIIA(N2) non-small-cell lung cancer. J Thorac Oncol. 2013 Jul; 8(7):915-22. PMID: 23608815.
      Citations: 34     Fields:    Translation:Humans
    200. Natarajan V, Dudek SM, Jacobson JR, Moreno-Vinasco L, Huang LS, Abassi T, Mathew B, Zhao Y, Wang L, Bittman R, Weichselbaum R, Berdyshev E, Garcia JG. Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury. Am J Respir Cell Mol Biol. 2013 Jul; 49(1):6-17. PMID: 23449739; PMCID: PMC3727889.
      Citations: 79     Fields:    Translation:HumansAnimals
    201. Grdina DJ, Murley JS, Miller RC, Mauceri HJ, Sutton HG, Li JJ, Woloschak GE, Weichselbaum RR. A survivin-associated adaptive response in radiation therapy. Cancer Res. 2013 Jul 15; 73(14):4418-28. PMID: 23651635; PMCID: PMC3721325.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    202. Liang H, Deng L, Chmura S, Burnette B, Liadis N, Darga T, Beckett MA, Lingen MW, Witt M, Weichselbaum RR, Fu YX. Radiation-induced equilibrium is a balance between tumor cell proliferation and T cell-mediated killing. J Immunol. 2013 Jun 01; 190(11):5874-81. PMID: 23630355; PMCID: PMC3660450.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    203. Corbin KS, Hellman S, Weichselbaum RR. Extracranial oligometastases: a subset of metastases curable with stereotactic radiotherapy. J Clin Oncol. 2013 Apr 10; 31(11):1384-90. PMID: 23460715.
      Citations: 73     Fields:    Translation:Humans
    204. Liauw SL, Connell PP, Weichselbaum RR. New paradigms and future challenges in radiation oncology: an update of biological targets and technology. Sci Transl Med. 2013 Feb 20; 5(173):173sr2. PMID: 23427246; PMCID: PMC3769139.
      Citations: 98     Fields:    Translation:Humans
    205. Rudra S, Malik R, Ranck MC, Farrey K, Golden DW, Hasselle MD, Weichselbaum RR, Salama JK. Stereotactic body radiation therapy for curative treatment of adrenal metastases. Technol Cancer Res Treat. 2013 Jun; 12(3):217-24. PMID: 23369155.
      Citations: 24     Fields:    Translation:Humans
    206. Solanki AA, Weichselbaum RR, Appelbaum D, Farrey K, Yenice KM, Chmura SJ, Salama JK. The utility of FDG-PET for assessing outcomes in oligometastatic cancer patients treated with stereotactic body radiotherapy: a cohort study. Radiat Oncol. 2012 Dec 18; 7:216. PMID: 23244066; PMCID: PMC3551831.
      Citations: 11     Fields:    Translation:Humans
    207. Grdina DJ, Murley JS, Miller RC, Mauceri HJ, Sutton HG, Thirman MJ, Li JJ, Woloschak GE, Weichselbaum RR. A manganese superoxide dismutase (SOD2)-mediated adaptive response. Radiat Res. 2013 Feb; 179(2):115-24. PMID: 23237540; PMCID: PMC3594688.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    208. Lussier YA, Khodarev NN, Regan K, Corbin K, Li H, Ganai S, Khan SA, Gnerlich JL, Gnerlich J, Darga TE, Fan H, Karpenko O, Paty PB, Posner MC, Chmura SJ, Hellman S, Ferguson MK, Weichselbaum RR. Oligo- and polymetastatic progression in lung metastasis(es) patients is associated with specific microRNAs. PLoS One. 2012; 7(12):e50141. PMID: 23251360; PMCID: PMC3518475.
      Citations: 71     Fields:    Translation:Humans
    209. Crawley CD, Raleigh DR, Kang S, Voce DJ, Schmitt AM, Weichselbaum RR, Yamini B. DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site. Nucleic Acids Res. 2013 Jan; 41(2):764-74. PMID: 23180782; PMCID: PMC3553961.
      Citations: 15     Fields:    Translation:AnimalsCells
    210. Seiwert TY, Darga T, Haraf D, Blair EA, Stenson K, Cohen EE, Salama JK, Villaflor V, Witt ME, Lingen MW, Weichselbaum RR, Vokes EE. A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade? Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation. Ann Oncol. 2013 Mar; 24(3):769-76. PMID: 23104721; PMCID: PMC3662388.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    211. Burnette B, Fu YX, Weichselbaum RR. The confluence of radiotherapy and immunotherapy. Front Oncol. 2012; 2:143. PMID: 23087904; PMCID: PMC3472545.
      Citations: 31     
    212. Poirot M, Silvente-Poirot S, Weichselbaum RR. Cholesterol metabolism and resistance to tamoxifen. Curr Opin Pharmacol. 2012 Dec; 12(6):683-9. PMID: 23063783.
      Citations: 20     Fields:    Translation:HumansCells
    213. Pitroda SP, Zhou T, Sweis RF, Filippo M, Labay E, Beckett MA, Mauceri HJ, Liang H, Darga TE, Perakis S, Khan SA, Sutton HG, Zhang W, Khodarev NN, Garcia JG, Weichselbaum RR. Tumor endothelial inflammation predicts clinical outcome in diverse human cancers. PLoS One. 2012; 7(10):e46104. PMID: 23056240; PMCID: PMC3464251.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    214. Corbin KS, Ranck MC, Hasselle MD, Golden DW, Partouche J, Wu T, Chmura SJ, Weichselbaum RR, Salama JK. Feasibility and toxicity of hypofractionated image guided radiation therapy for large volume limited metastatic disease. Pract Radiat Oncol. 2013 Oct-Dec; 3(4):316-22. PMID: 24674404.
      Citations: 8     Fields:    
    215. Jin C, Rajabi H, Pitroda S, Li A, Kharbanda A, Weichselbaum R, Kufe D. Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells. PLoS One. 2012; 7(7):e39432. PMID: 22792175; PMCID: PMC3392244.
      Citations: 26     Fields:    Translation:HumansCells
    216. Gorshkova I, Zhou T, Mathew B, Jacobson JR, Takekoshi D, Bhattacharya P, Smith B, Aydogan B, Weichselbaum RR, Natarajan V, Garcia JG, Berdyshev EV. Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression. J Lipid Res. 2012 Aug; 53(8):1553-68. PMID: 22615416; PMCID: PMC3540856.
      Citations: 27     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    217. Khodarev NN, Roizman B, Weichselbaum RR. Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth. Clin Cancer Res. 2012 Jun 01; 18(11):3015-21. PMID: 22615451.
      Citations: 98     Fields:    Translation:HumansCells
    218. Skelly CL, He Q, Spiguel L, McCormick S, Weichselbaum R. Modulating vascular intimal hyperplasia using HSV-1 mutant requires activated MEK. Gene Ther. 2013 Feb; 20(2):215-24. PMID: 22418062; PMCID: PMC3567261.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    219. Schreiber K, Arina A, Engels B, Spiotto MT, Sidney J, Sette A, Karrison TG, Weichselbaum RR, Rowley DA, Schreiber H. Spleen cells from young but not old immunized mice eradicate large established cancers. Clin Cancer Res. 2012 May 01; 18(9):2526-33. PMID: 22415314; PMCID: PMC5354938.
      Citations: 16     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    220. Meng Y, Efimova EV, Hamzeh KW, Darga TE, Mauceri HJ, Fu YX, Kron SJ, Weichselbaum RR. Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine. Mol Ther. 2012 May; 20(5):1046-55. PMID: 22334019; PMCID: PMC3345982.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    221. Hasselle MD, Haraf DJ, Rusthoven KE, Golden DW, Salgia R, Villaflor VM, Shah N, Hoffman PC, Chmura SJ, Connell PP, Vokes EE, Weichselbaum RR, Salama JK. Hypofractionated image-guided radiation therapy for patients with limited volume metastatic non-small cell lung cancer. J Thorac Oncol. 2012 Feb; 7(2):376-81. PMID: 22198429.
      Citations: 35     Fields:    Translation:Humans
    222. Mauceri HJ, Sutton HG, Darga TE, Kocherginsky M, Kochanski J, Weichselbaum RR, Vokes EE. Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer. Oncol Rep. 2012 May; 27(5):1625-9. PMID: 22294050.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    223. Duarte CW, Willey CD, Zhi D, Cui X, Harris JJ, Vaughan LK, Mehta T, McCubrey RO, Khodarev NN, Weichselbaum RR, Gillespie GY. Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner. PLoS One. 2012; 7(1):e29653. PMID: 22242177; PMCID: PMC3252343.
      Citations: 62     Fields:    Translation:HumansCells
    224. Lussier YA, Xing HR, Salama JK, Khodarev NN, Huang Y, Zhang Q, Khan SA, Yang X, Hasselle MD, Darga TE, Malik R, Fan H, Perakis S, Filippo M, Corbin K, Lee Y, Posner MC, Chmura SJ, Hellman S, Weichselbaum RR. MicroRNA expression characterizes oligometastasis(es). PLoS One. 2011; 6(12):e28650. PMID: 22174856; PMCID: PMC3236765.
      Citations: 95     Fields:    Translation:HumansAnimalsCells
    225. Schmitt AM, Crawley CD, Kang S, Raleigh DR, Yu X, Wahlstrom JS, Voce DJ, Darga TE, Weichselbaum RR, Yamini B. p50 (NF-?B1) is an effector protein in the cytotoxic response to DNA methylation damage. Mol Cell. 2011 Dec 09; 44(5):785-96. PMID: 22152481; PMCID: PMC3240852.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    226. Soneru AP, Beckett MA, Weichselbaum RR, Lee RC. Mg ATP and antioxidants augment the radioprotective effect of surfactant copolymers. Health Phys. 2011 Dec; 101(6):731-8. PMID: 22048491; PMCID: PMC3208161.
      Citations: 1     Fields:    Translation:AnimalsCells
    227. Elas M, Hleihel D, Barth ED, Haney CR, Ahn KH, Pelizzari CA, Epel B, Weichselbaum RR, Halpern HJ. Where it's at really matters: in situ in vivo vascular endothelial growth factor spatially correlates with electron paramagnetic resonance pO2 images in tumors of living mice. Mol Imaging Biol. 2011 Dec; 13(6):1107-13. PMID: 20960236; PMCID: PMC3210947.
      Citations: 16     Fields:    Translation:HumansAnimals
    228. Salama JK, Hasselle MD, Chmura SJ, Malik R, Mehta N, Yenice KM, Villaflor VM, Stadler WM, Hoffman PC, Cohen EE, Connell PP, Haraf DJ, Vokes EE, Hellman S, Weichselbaum RR. Stereotactic body radiotherapy for multisite extracranial oligometastases: final report of a dose escalation trial in patients with 1 to 5 sites of metastatic disease. Cancer. 2012 Jun 01; 118(11):2962-70. PMID: 22020702.
      Citations: 122     Fields:    Translation:HumansCTClinical Trials
    229. Koshy M, Villano JL, Dolecek TA, Howard A, Mahmood U, Chmura SJ, Weichselbaum RR, McCarthy BJ. Improved survival time trends for glioblastoma using the SEER 17 population-based registries. J Neurooncol. 2012 Mar; 107(1):207-12. PMID: 21984115; PMCID: PMC4077033.
      Citations: 201     Fields:    Translation:Humans
    230. Murley JS, Baker KL, Miller RC, Darga TE, Weichselbaum RR, Grdina DJ. SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine. Free Radic Biol Med. 2011 Nov 15; 51(10):1918-25. PMID: 21945096; PMCID: PMC3200566.
      Citations: 11     Fields:    Translation:AnimalsCells
    231. Connell PP, Weichselbaum RR. A downside to apoptosis in cancer therapy? Nat Med. 2011 Jul 07; 17(7):780-2. PMID: 21738153.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    232. Wu TH, Schreiber K, Arina A, Khodarev NN, Efimova EV, Rowley DA, Weichselbaum RR, Schreiber H. Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes. Cancer Immun. 2011 Jun 30; 11:2. PMID: 21714479; PMCID: PMC3127375.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    233. Mathew B, Jacobson JR, Berdyshev E, Huang Y, Sun X, Zhao Y, Gerhold LM, Siegler J, Evenoski C, Wang T, Zhou T, Zaidi R, Moreno-Vinasco L, Bittman R, Chen CT, LaRiviere PJ, Sammani S, Lussier YA, Dudek SM, Natarajan V, Weichselbaum RR, Garcia JG. Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs. FASEB J. 2011 Oct; 25(10):3388-400. PMID: 21712494; PMCID: PMC3177585.
      Citations: 39     Fields:    Translation:AnimalsPHPublic Health
    234. Barreto-Andrade JC, Efimova EV, Mauceri HJ, Beckett MA, Sutton HG, Darga TE, Vokes EE, Posner MC, Kron SJ, Weichselbaum RR. Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation. Mol Cancer Ther. 2011 Jul; 10(7):1185-93. PMID: 21571912; PMCID: PMC3140695.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    235. Advani SJ, Markert JM, Sood RF, Samuel S, Gillespie GY, Shao MY, Roizman B, Weichselbaum RR. Increased oncolytic efficacy for high-grade gliomas by optimal integration of ionizing radiation into the replicative cycle of HSV-1. Gene Ther. 2011 Nov; 18(11):1098-102. PMID: 21544094; PMCID: PMC8670556.
      Citations: 22     Fields:    Translation:AnimalsCells
    236. Weichselbaum RR, Hellman S. Oligometastases revisited. Nat Rev Clin Oncol. 2011 06; 8(6):378-82. PMID: 21423255.
      Citations: 332     Fields:    Translation:Humans
    237. Labay E, Efimova EV, Quarshie BK, Golden DW, Weichselbaum RR, Kron SJ. Ionizing radiation-induced foci persistence screen to discover enhancers of accelerated senescence. Int J High Throughput Screen. 2011 Mar; 2:1-13. PMID: 26097382; PMCID: PMC4474479.
      Citations: 11     
    238. Burnette BC, Liang H, Lee Y, Chlewicki L, Khodarev NN, Weichselbaum RR, Fu YX, Auh SL. The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity. Cancer Res. 2011 Apr 01; 71(7):2488-96. PMID: 21300764; PMCID: PMC3070872.
      Citations: 381     Fields:    Translation:AnimalsCells
    239. Kuo WL, Liu J, Mauceri H, Vokes EE, Weichselbaum R, Rosner MR, Cohen EE. Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context. Mol Cancer Ther. 2010 Oct; 9(10):2814-24. PMID: 20876745; PMCID: PMC2953602.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    240. Mell LK, Jeong JH, Nichols MA, Polite BN, Weichselbaum RR, Chmura SJ. Predictors of competing mortality in early breast cancer. Cancer. 2010 Dec 01; 116(23):5365-73. PMID: 20737562.
      Citations: 14     Fields:    Translation:Humans
    241. Gutt R, Liauw SL, Weichselbaum RR. The role of radiotherapy in locally advanced pancreatic carcinoma. Nat Rev Gastroenterol Hepatol. 2010 Aug; 7(8):437-47. PMID: 20628346.
      Citations: 19     Fields:    Translation:Humans
    242. Efimova EV, Mauceri HJ, Golden DW, Labay E, Bindokas VP, Darga TE, Chakraborty C, Barreto-Andrade JC, Crawley C, Sutton HG, Kron SJ, Weichselbaum RR. Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors. Cancer Res. 2010 Aug 01; 70(15):6277-82. PMID: 20610628; PMCID: PMC2912962.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    243. Mathew B, Huang Y, Jacobson JR, Berdyshev E, Gerhold LM, Wang T, Moreno-Vinasco L, Lang G, Zhao Y, Chen CT, LaRiviere PJ, Mauceri H, Sammani S, Husain AN, Dudek SM, Natarajan V, Lussier YA, Weichselbaum RR, Garcia JG. Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression. Am J Respir Cell Mol Biol. 2011 Mar; 44(3):415-22. PMID: 20508068; PMCID: PMC3095940.
      Citations: 33     Fields:    Translation:AnimalsCellsPHPublic Health
    244. MacDermed DM, Khodarev NN, Pitroda SP, Edwards DC, Pelizzari CA, Huang L, Kufe DW, Weichselbaum RR. MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients. BMC Med Genomics. 2010 May 06; 3:16. PMID: 20459602; PMCID: PMC2876055.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    245. Maitland ML, Lou XJ, Ramirez J, Desai AA, Berlin DS, McLeod HL, Weichselbaum RR, Ratain MJ, Altman RB, Klein TE. Vascular endothelial growth factor pathway. Pharmacogenet Genomics. 2010 May; 20(5):346-9. PMID: 20124951; PMCID: PMC3086058.
      Citations: 10     Fields:    Translation:Humans
    246. Nichols MA, Mell LK, Hasselle MD, Karrison TG, MacDermed D, Meriwether A, Witt ME, Weichselbaum RR, Chmura SJ. Outcomes in black patients with early breast cancer treated with breast conservation therapy. Int J Radiat Oncol Biol Phys. 2011 Feb 01; 79(2):392-9. PMID: 20434849.
      Citations: 1     Fields:    Translation:Humans
    247. Gutt R, Tonlaar N, Kunnavakkam R, Karrison T, Weichselbaum RR, Liauw SL. Statin use and risk of prostate cancer recurrence in men treated with radiation therapy. J Clin Oncol. 2010 Jun 01; 28(16):2653-9. PMID: 20421534.
      Citations: 74     Fields:    Translation:Humans
    248. Lee Y, Yang X, Huang Y, Fan H, Zhang Q, Wu Y, Li J, Hasina R, Cheng C, Lingen MW, Gerstein MB, Weichselbaum RR, Xing HR, Lussier YA. Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis. PLoS Comput Biol. 2010 Apr 01; 6(4):e1000730. PMID: 20369013; PMCID: PMC2848541.
      Citations: 86     Fields:    Translation:HumansCells
    249. Meng Y, Mauceri HJ, Khodarev NN, Darga TE, Pitroda SP, Beckett MA, Kufe DW, Weichselbaum RR. Ad.Egr-TNF and local ionizing radiation suppress metastases by interferon-beta-dependent activation of antigen-specific CD8+ T cells. Mol Ther. 2010 May; 18(5):912-20. PMID: 20197756; PMCID: PMC2890103.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    250. Huang L, Liao X, Beckett M, Li Y, Khanna KK, Wang Z, Kharbanda S, Weichselbaum R, Kufe D. MUC1-C Oncoprotein Interacts Directly with ATM and Promotes the DNA Damage Response to Ionizing Radiation. Genes Cancer. 2010 Mar; 1(3):239-250. PMID: 20865059; PMCID: PMC2943399.
      Citations: 15     
    251. Meng Y, Beckett MA, Liang H, Mauceri HJ, van Rooijen N, Cohen KS, Weichselbaum RR. Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy. Cancer Res. 2010 Feb 15; 70(4):1534-43. PMID: 20145121; PMCID: PMC8849568.
      Citations: 87     Fields:    Translation:AnimalsCells
    252. Mell LK, Dignam JJ, Salama JK, Cohen EE, Polite BN, Dandekar V, Bhate AD, Witt ME, Haraf DJ, Mittal BB, Vokes EE, Weichselbaum RR. Predictors of competing mortality in advanced head and neck cancer. J Clin Oncol. 2010 Jan 01; 28(1):15-20. PMID: 19933920.
      Citations: 46     Fields:    Translation:Humans
    253. Khodarev N, Ahmad R, Rajabi H, Pitroda S, Kufe T, McClary C, Joshi MD, MacDermed D, Weichselbaum R, Kufe D. Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. Oncogene. 2010 Feb 11; 29(6):920-9. PMID: 19915608; PMCID: PMC2820589.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    254. Pitroda SP, Wakim BT, Sood RF, Beveridge MG, Beckett MA, MacDermed DM, Weichselbaum RR, Khodarev NN. STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect. BMC Med. 2009 Nov 05; 7:68. PMID: 19891767; PMCID: PMC2780454.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    255. Valuckaite V, Zaborina O, Long J, Hauer-Jensen M, Wang J, Holbrook C, Zaborin A, Drabik K, Katdare M, Mauceri H, Weichselbaum R, Firestone MA, Lee KY, Chang EB, Matthews J, Alverdy JC. Oral PEG 15-20 protects the intestine against radiation: role of lipid rafts. Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6):G1041-52. PMID: 19833862; PMCID: PMC2850088.
      Citations: 18     Fields:    Translation:AnimalsCellsPHPublic Health
    256. Uriel S, Labay E, Francis-Sedlak M, Moya ML, Weichselbaum RR, Ervin N, Cankova Z, Brey EM. Extraction and assembly of tissue-derived gels for cell culture and tissue engineering. Tissue Eng Part C Methods. 2009 Sep; 15(3):309-21. PMID: 19115821; PMCID: PMC2863083.
      Citations: 40     Fields:    Translation:HumansAnimals
    257. Liauw SL, Stadler WM, Correa D, Weichselbaum RR, Jani AB. Dose-escalated radiotherapy for high-risk prostate cancer: outcomes in modern era with short-term androgen deprivation therapy. Int J Radiat Oncol Biol Phys. 2010 May 01; 77(1):125-30. PMID: 19695789; PMCID: PMC3049990.
      Citations: 4     Fields:    Translation:Humans
    258. Haney CR, Parasca AD, Fan X, Bell RM, Zamora MA, Karczmar GS, Mauceri HJ, Halpern HJ, Weichselbaum RR, Pelizzari CA. Characterization of response to radiation mediated gene therapy by means of multimodality imaging. Magn Reson Med. 2009 Aug; 62(2):348-56. PMID: 19449382; PMCID: PMC2785132.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    259. Cohen EE, Baru J, Huo D, Haraf DJ, Crowley M, Witt ME, Blair EA, Weichselbaum RR, Rosen F, Vokes EE, Stenson K. Efficacy and safety of treating T4 oral cavity tumors with primary chemoradiotherapy. Head Neck. 2009 Aug; 31(8):1013-21. PMID: 19340870.
      Citations: 10     Fields:    Translation:Humans
    260. Khodarev NN, Roach P, Pitroda SP, Golden DW, Bhayani M, Shao MY, Darga TE, Beveridge MG, Sood RF, Sutton HG, Beckett MA, Mauceri HJ, Posner MC, Weichselbaum RR. STAT1 pathway mediates amplification of metastatic potential and resistance to therapy. PLoS One. 2009 Jun 08; 4(6):e5821. PMID: 19503789; PMCID: PMC2688034.
      Citations: 65     Fields:    Translation:AnimalsCells
    261. Liauw SL, Weichselbaum RR, Rash C, Correa D, Al-Hallaq HA, Pelizzari CA, Jani AB. Biochemical control and toxicity after intensity-modulated radiation therapy for prostate cancer. Technol Cancer Res Treat. 2009 Jun; 8(3):201-6. PMID: 19445537.
      Citations: 6     Fields:    Translation:Humans
    262. Weichselbaum RR, Kufe D. Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers. Cancer Gene Ther. 2009 Aug; 16(8):609-19. PMID: 19444302.
      Citations: 19     Fields:    Translation:Humans
    263. Efimova EV, Liang H, Pitroda SP, Labay E, Darga TE, Levina V, Lokshin A, Roizman B, Weichselbaum RR, Khodarev NN. Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling. Int J Radiat Biol. 2009 May; 85(5):421-31. PMID: 19437244; PMCID: PMC2690884.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    264. Liauw SL, Fricano J, Correa D, Weichselbaum RR, Jani AB. Dose-escalated radiation therapy for intermediate-risk prostate cancer: patient selection for androgen deprivation therapy using percentage of positive cores. Cancer. 2009 Apr 15; 115(8):1784-90. PMID: 19208426.
      Citations: 4     Fields:    Translation:Humans
    265. Lee Y, Auh SL, Wang Y, Burnette B, Wang Y, Meng Y, Beckett M, Sharma R, Chin R, Tu T, Weichselbaum RR, Fu YX. Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment. Blood. 2009 Jul 16; 114(3):589-95. PMID: 19349616; PMCID: PMC2713472.
      Citations: 590     Fields:    Translation:AnimalsCells
    266. Khodarev NN, Pitroda SP, Beckett MA, MacDermed DM, Huang L, Kufe DW, Weichselbaum RR. MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer. Cancer Res. 2009 Apr 01; 69(7):2833-7. PMID: 19318547; PMCID: PMC3034477.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    267. Pitroda SP, Khodarev NN, Beckett MA, Kufe DW, Weichselbaum RR. MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5837-41. PMID: 19289846; PMCID: PMC2656554.
      Citations: 63     Fields:    Translation:Humans
    268. Weichselbaum RR. MUCing around with tumor suppression. Cancer Biol Ther. 2008 Dec; 7(12):1968-9. PMID: 18981734.
      Citations:    Fields:    Translation:Humans
    269. Spiguel LR, Chandiwal A, Vosicky JE, Weichselbaum RR, Skelly CL. Concomitant proliferation and caspase-3 mediated apoptosis in response to low shear stress and balloon injury. J Surg Res. 2010 Jun 01; 161(1):146-55. PMID: 19482308; PMCID: PMC2906117.
      Citations: 7     Fields:    Translation:AnimalsCells
    270. Gutt R, Liauw SL, Weichselbaum RR. Adjuvant radiotherapy for resected pancreatic cancer: a lack of benefit or a lack of adequate trials? Nat Clin Pract Gastroenterol Hepatol. 2009 Jan; 6(1):38-46. PMID: 19029997.
      Citations: 4     Fields:    Translation:Humans
    271. Weichselbaum RR, Ishwaran H, Yoon T, Nuyten DS, Baker SW, Khodarev N, Su AW, Shaikh AY, Roach P, Kreike B, Roizman B, Bergh J, Pawitan Y, van de Vijver MJ, Minn AJ. An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18490-5. PMID: 19001271; PMCID: PMC2587578.
      Citations: 281     Fields:    Translation:HumansAnimalsCells
    272. Al-Hallaq HA, Mell LK, Bradley JA, Chen LF, Ali AN, Weichselbaum RR, Newstead GM, Chmura SJ. Magnetic resonance imaging identifies multifocal and multicentric disease in breast cancer patients who are eligible for partial breast irradiation. Cancer. 2008 Nov 01; 113(9):2408-14. PMID: 18823018.
      Citations: 15     Fields:    Translation:Humans
    273. Mauceri HJ, Beckett MA, Liang H, Sutton HG, Pitroda S, Galka E, Efimova E, Darga T, Khodarev NN, King CR, Posner MC, Hellman S, Kufe DW, Weichselbaum RR. Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy. Cancer Gene Ther. 2009 Apr; 16(4):373-81. PMID: 18974777; PMCID: PMC5705082.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    274. Jayathilaka K, Sheridan SD, Bold TD, Bochenska K, Logan HL, Weichselbaum RR, Bishop DK, Connell PP. A chemical compound that stimulates the human homologous recombination protein RAD51. Proc Natl Acad Sci U S A. 2008 Oct 14; 105(41):15848-53. PMID: 18840682; PMCID: PMC2572930.
      Citations: 78     Fields:    Translation:HumansCells
    275. Macdermed DM, Weichselbaum RR, Salama JK. A rationale for the targeted treatment of oligometastases with radiotherapy. J Surg Oncol. 2008 Sep 01; 98(3):202-6. PMID: 18618604.
      Citations: 43     Fields:    Translation:Humans
    276. Salama JK, Chmura SJ, Mehta N, Yenice KM, Stadler WM, Vokes EE, Haraf DJ, Hellman S, Weichselbaum RR. An initial report of a radiation dose-escalation trial in patients with one to five sites of metastatic disease. Clin Cancer Res. 2008 Aug 15; 14(16):5255-9. PMID: 18698045.
      Citations: 42     Fields:    Translation:HumansCTClinical Trials
    277. Seiwert TY, Haraf DJ, Cohen EE, Stenson K, Witt ME, Dekker A, Kocherginsky M, Weichselbaum RR, Chen HX, Vokes EE. Phase I study of bevacizumab added to fluorouracil- and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer. J Clin Oncol. 2008 Apr 01; 26(10):1732-41. PMID: 18375903.
      Citations: 47     Fields:    Translation:HumansCTClinical Trials
    278. Liauw SL, Weichselbaum RR, Zagaja GP, Jani AB. Salvage radiotherapy after postprostatectomy biochemical failure: does pretreatment radioimmunoscintigraphy help select patients with locally confined disease? Int J Radiat Oncol Biol Phys. 2008 Aug 01; 71(5):1316-21. PMID: 18234446.
      Citations: 2     Fields:    Translation:Humans
    279. Bickenbach KA, Veerapong J, Shao MY, Mauceri HJ, Posner MC, Kron SJ, Weichselbaum RR. Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy. Cancer Gene Ther. 2008 Mar; 15(3):133-9. PMID: 18157146.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    280. Katdare M, Efimova EV, Labay E, Khodarev NN, Darga TE, Garofalo M, Nakamura S, Kufe DW, Posner MC, Weichselbaum RR. Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB. Int J Oncol. 2007 Dec; 31(6):1519-28. PMID: 17982679.
      Citations: 5     Fields:    Translation:HumansCells
    281. Mell LK, Weichselbaum RR. More on cetuximab in head and neck cancer. N Engl J Med. 2007 Nov 22; 357(21):2201-2; author reply 2202-3. PMID: 18032774.
      Citations: 6     Fields:    Translation:Humans
    282. Yamini B, Yu X, Pytel P, Galanopoulos N, Rawlani V, Veerapong J, Bickenbach K, Weichselbaum RR. Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy. Clin Cancer Res. 2007 Oct 15; 13(20):6217-23. PMID: 17947489.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    283. Roeske JC, Nunez L, Hoggarth M, Labay E, Weichselbaum RR. Characterization of the theorectical radiation dose enhancement from nanoparticles. Technol Cancer Res Treat. 2007 Oct; 6(5):395-401. PMID: 17877427.
      Citations: 42     Fields:    Translation:HumansAnimals
    284. Smith KD, Shao MY, Posner MC, Weichselbaum RR. Tumor genotype determines susceptibility to oncolytic herpes simplex virus mutants: strategies for clinical application. Future Oncol. 2007 Oct; 3(5):545-56. PMID: 17927520.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    285. Khodarev NN, Minn AJ, Efimova EV, Darga TE, Labay E, Beckett M, Mauceri HJ, Roizman B, Weichselbaum RR. Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells. Cancer Res. 2007 Oct 01; 67(19):9214-20. PMID: 17909027.
      Citations: 73     Fields:    Translation:HumansAnimals
    286. Advani SJ, Weichselbaum RR, Chmura SJ. Enhancing radiotherapy with genetically engineered viruses. J Clin Oncol. 2007 Sep 10; 25(26):4090-5. PMID: 17827458.
      Citations: 2     Fields:    Translation:HumansCells
    287. Veerapong J, Bickenbach KA, Shao MY, Smith KD, Posner MC, Roizman B, Weichselbaum RR. Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity. Cancer Res. 2007 Sep 01; 67(17):8301-6. PMID: 17804745.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    288. MacGill RS, Davis TA, Macko J, Mauceri HJ, Weichselbaum RR, King CR. Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response. Clin Exp Metastasis. 2007; 24(7):521-31. PMID: 17653822.
      Citations: 13     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    289. Yamini B, Yu X, Dolan ME, Wu MH, Darga TE, Kufe DW, Weichselbaum RR. Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding. Cancer Res. 2007 Jul 15; 67(14):6889-98. PMID: 17638900.
      Citations: 20     Fields:    Translation:HumansCells
    290. Skelly CL, Chandiwal A, Vosicky JE, Weichselbaum RR, Roizman B. Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flow. Proc Natl Acad Sci U S A. 2007 Jul 24; 104(30):12474-8. PMID: 17626787; PMCID: PMC1941493.
      Citations: 9     Fields:    Translation:AnimalsCells
    291. Sharma RR, Weichselbaum RR. Angiogenesis inhibition: the next frontier in multimodal therapy for glioblastoma multiforme. Nat Clin Pract Oncol. 2007 Aug; 4(8):454-5. PMID: 17609654.
      Citations:    Fields:    
    292. Zhang B, Bowerman NA, Salama JK, Schmidt H, Spiotto MT, Schietinger A, Yu P, Fu YX, Weichselbaum RR, Rowley DA, Kranz DM, Schreiber H. Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. J Exp Med. 2007 Jan 22; 204(1):49-55. PMID: 17210731; PMCID: PMC2118433.
      Citations: 183     Fields:    Translation:AnimalsCellsPHPublic Health
    293. Advani SJ, Mezhir JJ, Roizman B, Weichselbaum RR. ReVOLT: radiation-enhanced viral oncolytic therapy. Int J Radiat Oncol Biol Phys. 2006 Nov 01; 66(3):637-46. PMID: 17011442.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    294. Mezhir JJ, Smith KD, Kimchi ET, Park JO, Lopez CA, Mauceri HJ, Beckett MA, Hellman S, Weichselbaum RR, Posner MC. Establishment of a syngeneic model of hepatic colorectal oligometastases. J Surg Res. 2006 Dec; 136(2):288-93. PMID: 16930623.
      Citations: 1     Fields:    Translation:Animals
    295. Kao J, Milano MT, Javaheri A, Garofalo MC, Chmura SJ, Weichselbaum RR, Kron SJ. gamma-H2AX as a therapeutic target for improving the efficacy of radiation therapy. Curr Cancer Drug Targets. 2006 May; 6(3):197-205. PMID: 16712457.
      Citations: 33     Fields:    Translation:Humans
    296. Connell PP, Jayathilaka K, Haraf DJ, Weichselbaum RR, Vokes EE, Lingen MW. Pilot study examining tumor expression of RAD51 and clinical outcomes in human head cancers. Int J Oncol. 2006 May; 28(5):1113-9. PMID: 16596227.
      Citations: 27     Fields:    Translation:HumansCells
    297. Milano MT, Vokes EE, Kao J, Jackson W, List MA, Stenson KM, Witt ME, Dekker A, MacCracken E, Garofalo MC, Chmura SJ, Weichselbaum RR, Haraf DJ. Intensity-modulated radiation therapy in advanced head and neck patients treated with intensive chemoradiotherapy: preliminary experience and future directions. Int J Oncol. 2006 May; 28(5):1141-51. PMID: 16596230.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    298. Jani AB, Feinstein JM, Pasciak R, Krengel S, Weichselbaum RR. Role of external beam radiotherapy with low-dose-rate brachytherapy in treatment of prostate cancer. Urology. 2006 May; 67(5):1007-11. PMID: 16635512.
      Citations: 4     Fields:    Translation:Humans
    299. Shafaee Z, Schmidt H, Du W, Posner M, Weichselbaum R. Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells. Cancer Chemother Pharmacol. 2006 Dec; 58(6):765-70. PMID: 16552573.
      Citations: 22     Fields:    Translation:HumansCells
    300. Smith KD, Mezhir JJ, Bickenbach K, Veerapong J, Charron J, Posner MC, Roizman B, Weichselbaum RR. Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1. J Virol. 2006 Feb; 80(3):1110-20. PMID: 16414988; PMCID: PMC1346955.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    301. Mezhir JJ, Smith KD, Posner MC, Senzer N, Yamini B, Kufe DW, Weichselbaum RR. Ionizing radiation: a genetic switch for cancer therapy. Cancer Gene Ther. 2006 Jan 01; 13(1):1-6. PMID: 16082378.
      Citations: 10     Fields:    Translation:HumansCells
    302. Mezhir JJ, Schmidt H, Yamini B, Senzer NN, Posner MC, Kufe DW, Weichselbaum RR. Chemo-inducible gene therapy. Anticancer Drugs. 2005 Nov; 16(10):1053-8. PMID: 16222146.
      Citations: 2     Fields:    Translation:HumansCells
    303. Mezhir JJ, Advani SJ, Smith KD, Darga TE, Poon AP, Schmidt H, Posner MC, Roizman B, Weichselbaum RR. Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses. Cancer Res. 2005 Oct 15; 65(20):9479-84. PMID: 16230412.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    304. Weichselbaum RR. Bugging the intestinal response to radiation. Proc Natl Acad Sci U S A. 2005 Sep 20; 102(38):13363-4. PMID: 16159964; PMCID: PMC1224667.
      Citations:    Fields:    Translation:HumansAnimals
    305. Murphy KT, Wardak A, Beckett MA, Lopez CA, Mehta N, Kimchi E, Salloum RM, Jaskowiak NT, Posner MC, Ohno T, Kufe DW, Weichselbaum RR, Mauceri HJ. Forphenicinol enhances the antitumor effects of cyclophosphamide in a model of squamous cell carcinoma. Cancer Chemother Pharmacol. 2005 Sep; 56(3):317-21. PMID: 15887016.
      Citations: 1     Fields:    Translation:AnimalsCells
    306. Weichselbaum RR. How does antiangiogenic therapy affect brain tumor response to radiation? Nat Clin Pract Oncol. 2005 May; 2(5):232-3. PMID: 16264953.
      Citations: 4     Fields:    Translation:Animals
    307. Weichselbaum R. Radiation's outer limits. Nat Med. 2005 May; 11(5):477-8. PMID: 15875051.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    308. Kimchi ET, Posner MC, Park JO, Darga TE, Kocherginsky M, Karrison T, Hart J, Smith KD, Mezhir JJ, Weichselbaum RR, Khodarev NN. Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation. Cancer Res. 2005 Apr 15; 65(8):3146-54. PMID: 15833844.
      Citations: 90     Fields:    Translation:HumansCells
    309. Milano MT, Vokes EE, Salama JK, Stenson KM, Kao J, Witt ME, Mittal BB, Argiris A, Weichselbaum RR, Haraf DJ. Twice-daily reirradiation for recurrent and second primary head-and-neck cancer with gemcitabine, paclitaxel, and 5-fluorouracil chemotherapy. Int J Radiat Oncol Biol Phys. 2005 Mar 15; 61(4):1096-106. PMID: 15752889.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    310. Hellman S, Weichselbaum RR. Importance of local control in an era of systemic therapy. Nat Clin Pract Oncol. 2005 Feb; 2(2):60-1. PMID: 16264859.
      Citations: 15     Fields:    Translation:Humans
    311. Raina D, Pandey P, Ahmad R, Bharti A, Ren J, Kharbanda S, Weichselbaum R, Kufe D. c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. J Biol Chem. 2005 Mar 25; 280(12):11147-51. PMID: 15657060.
      Citations: 22     Fields:    Translation:HumansCells
    312. Baldwin ZK, Chandiwal A, Balasubramanian V, Pearce BJ, Curi MA, Skelly CL, Huang WW, Vosicky JE, Roizman B, Weichselbaum RR, Schwartz LB. Modulation of vascular remodeling induced by a brief intraluminal exposure to the recombinant R7020 strain of Herpes simplex-1. J Vasc Surg. 2005 Jan; 41(1):115-21. PMID: 15696053.
      Citations: 2     Fields:    Translation:AnimalsCells
    313. Mehta N, Mauer AM, Hellman S, Haraf DJ, Cohen EE, Vokes EE, Weichselbaum RR. Analysis of further disease progression in metastatic non-small cell lung cancer: implications for locoregional treatment. Int J Oncol. 2004 Dec; 25(6):1677-83. PMID: 15547705.
      Citations: 43     Fields:    Translation:HumansCTClinical Trials
    314. Khodarev NN, Kataoka Y, Murley JS, Weichselbaum RR, Grdina DJ. Interaction of amifostine and ionizing radiation on transcriptional patterns of apoptotic genes expressed in human microvascular endothelial cells (HMEC). Int J Radiat Oncol Biol Phys. 2004 Oct 01; 60(2):553-63. PMID: 15380592.
      Citations: 12     Fields:    Translation:HumansCells
    315. Yamini B, Yu X, Gillespie GY, Kufe DW, Weichselbaum RR. Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma. Cancer Res. 2004 Sep 15; 64(18):6381-4. PMID: 15374943.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    316. Greenebaum B, Blossfield K, Hannig J, Carrillo CS, Beckett MA, Weichselbaum RR, Lee RC. Poloxamer 188 prevents acute necrosis of adult skeletal muscle cells following high-dose irradiation. Burns. 2004 Sep; 30(6):539-47. PMID: 15302418.
      Citations: 25     Fields:    Translation:AnimalsCellsPHPublic Health
    317. Mundt AJ, Vijayakumar S, Nemunaitis J, Sandler A, Schwartz H, Hanna N, Peabody T, Senzer N, Chu K, Rasmussen CS, Kessler PD, Rasmussen HS, Warso M, Kufe DW, Gupta TD, Weichselbaum RR. A Phase I trial of TNFerade biologic in patients with soft tissue sarcoma in the extremities. Clin Cancer Res. 2004 Sep 01; 10(17):5747-53. PMID: 15355902.
      Citations: 24     Fields:    Translation:HumansCellsCTClinical Trials
    318. Lopez CA, Kimchi ET, Mauceri HJ, Park JO, Mehta N, Murphy KT, Beckett MA, Hellman S, Posner MC, Kufe DW, Weichselbaum RR. Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity. Mol Cancer Ther. 2004 Sep; 3(9):1167-75. PMID: 15367711.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    319. Connell PP, Kron SJ, Weichselbaum RR. Relevance and irrelevance of DNA damage response to radiotherapy. DNA Repair (Amst). 2004 Aug-Sep; 3(8-9):1245-51. PMID: 15279813.
      Citations: 8     Fields:    Translation:HumansCells
    320. Jani AB, Blend MJ, Hamilton R, Brendler C, Pelizzari C, Krauz L, Sapra B, Vijayakumar S, Awan A, Weichselbaum RR. Radioimmunoscintigraphy for postprostatectomy radiotherapy: analysis of toxicity and biochemical control. J Nucl Med. 2004 Aug; 45(8):1315-22. PMID: 15299055.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    321. Brown CK, Khodarev NN, Yu J, Moo-Young T, Labay E, Darga TE, Posner MC, Weichselbaum RR, Mauceri HJ. Glioblastoma cells block radiation-induced programmed cell death of endothelial cells. FEBS Lett. 2004 May 07; 565(1-3):167-70. PMID: 15135073.
      Citations: 20     Fields:    Translation:HumansCells
    322. Connell PP, Siddiqui N, Hoffman S, Kuang A, Khatipov EA, Weichselbaum RR, Bishop DK. A hot spot for RAD51C interactions revealed by a peptide that sensitizes cells to cisplatin. Cancer Res. 2004 May 01; 64(9):3002-5. PMID: 15126333.
      Citations: 5     Fields:    Translation:Cells
    323. Jani AB, Blend MJ, Hamilton R, Brendler C, Pelizzari C, Krauz L, Vijayakumar S, Sapra B, Awan A, Weichselbaum RR. Influence of radioimmunoscintigraphy on postprostatectomy radiotherapy treatment decision making. J Nucl Med. 2004 Apr; 45(4):571-8. PMID: 15073252.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    324. Khodarev NN, Labay E, Darga T, Yu J, Mauceri H, Gupta N, Kataoka Y, Weichselbaum RR. Endothelial cells co-cultured with wild-type and dominant/negative p53-transfected glioblastoma cells exhibit differential sensitivity to radiation-induced apoptosis. Int J Cancer. 2004 Mar 20; 109(2):214-9. PMID: 14750172.
      Citations: 8     Fields:    Translation:HumansCells
    325. Lopez CA, Park JO, Mauceri HJ, Beckett MA, Weichselbaum RR, Posner MC. Control of gene therapy by MDR1 and EGR1 promoter sequences in transcriptional targeting by chemotherapy (Review). Int J Oncol. 2004 Mar; 24(3):731-6. PMID: 14767560.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    326. Jani AB, Spelbring D, Hamilton R, Blend MJ, Pelizzari C, Brendler C, Krauz L, Vijayakumar S, Sapra B, Weichselbaum RR. Impact of radioimmunoscintigraphy on definition of clinical target volume for radiotherapy after prostatectomy. J Nucl Med. 2004 Feb; 45(2):238-46. PMID: 14960642.
      Citations: 5     Fields:    Translation:Humans
    327. Khodarev NN, Beckett M, Labay E, Darga T, Roizman B, Weichselbaum RR. STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc Natl Acad Sci U S A. 2004 Feb 10; 101(6):1714-9. PMID: 14755057; PMCID: PMC341831.
      Citations: 146     Fields:    Translation:HumansAnimalsCells
    328. Senzer N, Mani S, Rosemurgy A, Nemunaitis J, Cunningham C, Guha C, Bayol N, Gillen M, Chu K, Rasmussen C, Rasmussen H, Kufe D, Weichselbaum R, Hanna N. TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors. J Clin Oncol. 2004 Feb 15; 22(4):592-601. PMID: 14726502.
      Citations: 56     Fields:    Translation:HumansCellsCTClinical Trials
    329. Haraf DJ, Rosen FR, Stenson K, Argiris A, Mittal BB, Witt ME, Brockstein BE, List MA, Portugal L, Pelzer H, Weichselbaum RR, Vokes EE. Induction chemotherapy followed by concomitant TFHX chemoradiotherapy with reduced dose radiation in advanced head and neck cancer. Clin Cancer Res. 2003 Dec 01; 9(16 Pt 1):5936-43. PMID: 14676118.
      Citations: 13     Fields:    Translation:Humans
    330. Advani SJ, Durand LO, Weichselbaum RR, Roizman B. Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1. J Virol. 2003 Nov; 77(22):11927-32. PMID: 14581529; PMCID: PMC254286.
      Citations: 5     Fields:    Translation:HumansCells
    331. Taneja N, Davis M, Choy JS, Beckett MA, Singh R, Kron SJ, Weichselbaum RR. Histone H2AX phosphorylation as a predictor of radiosensitivity and target for radiotherapy. J Biol Chem. 2004 Jan 16; 279(3):2273-80. PMID: 14561744.
      Citations: 99     Fields:    Translation:HumansAnimalsCells
    332. Bartelink H, Benz C, Cleveland D, Dorn R, Gralow J, Gradishar WJ, Grant K, Heimann R, Hellman S, Hudis C, Kerbel R, Lippman M, Lung J, Posner MC, Steeg P, Vestal R, Weichselbaum RR, Zetter B. Expedition Inspiration Fund for Breast Cancer Research Meeting 2003. Breast Cancer Res Treat. 2003 Jul; 80(2):139-44. PMID: 12908816.
      Citations:    Fields:    Translation:Humans
    333. Kufe D, Weichselbaum R. Radiation therapy: activation for gene transcription and the development of genetic radiotherapy-therapeutic strategies in oncology. Cancer Biol Ther. 2003 Jul-Aug; 2(4):326-9. PMID: 14508100.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    334. Connell PP, Weichselbaum RR. Gene therapy: the challenges of translating laboratory research into clinical practice. J Clin Oncol. 2003 Jun 15; 21(12):2230-1. PMID: 12805319.
      Citations: 2     Fields:    Translation:HumansCells
    335. Curi MA, Skelly CL, Meyerson SL, Baldwin ZK, Balasubramanian V, Advani SJ, Glagov S, Roizman B, Weichselbaum RR, Schwartz LB. Sustained inhibition of experimental neointimal hyperplasia with a genetically modified herpes simplex virus. J Vasc Surg. 2003 Jun; 37(6):1294-300. PMID: 12764278.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    336. Rosen FR, Haraf DJ, Kies MS, Stenson K, Portugal L, List MA, Brockstein BE, Mittal BB, Rademaker AW, Witt ME, Pelzer H, Weichselbaum RR, Vokes EE. Multicenter randomized Phase II study of paclitaxel (1-hour infusion), fluorouracil, hydroxyurea, and concomitant twice daily radiation with or without erythropoietin for advanced head and neck cancer. Clin Cancer Res. 2003 May; 9(5):1689-97. PMID: 12738722.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    337. Oh JL, Vokes EE, Kies MS, Mittal BB, Witt ME, Weichselbaum RR, Haraf DJ. Induction chemotherapy followed by concomitant chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal cancer. Ann Oncol. 2003 Apr; 14(4):564-9. PMID: 12649102.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    338. Advani SJ, Weichselbaum RR, Roizman B. Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4825-30. PMID: 12665617; PMCID: PMC153640.
      Citations: 30     Fields:    Translation:HumansCells
    339. Khodarev NN, Yu J, Labay E, Darga T, Brown CK, Mauceri HJ, Yassari R, Gupta N, Weichselbaum RR. Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells. J Cell Sci. 2003 Mar 15; 116(Pt 6):1013-22. PMID: 12584245.
      Citations: 83     Fields:    Translation:HumansCells
    340. Khodarev NN, Park J, Kataoka Y, Nodzenski E, Hellman S, Roizman B, Weichselbaum RR, Pelizzari CA. Receiver operating characteristic analysis: a general tool for DNA array data filtration and performance estimation. Genomics. 2003 Feb; 81(2):202-9. PMID: 12620398.
      Citations: 12     Fields:    
    341. Gupta VK, Park JO, Kurihara T, Koons A, Mauceri HJ, Jaskowiak NT, Kufe DW, Weichselbaum RR, Posner MC. Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model. Gene Ther. 2003 Feb; 10(3):206-12. PMID: 12571627.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    342. Vokes EE, Stenson K, Rosen FR, Kies MS, Rademaker AW, Witt ME, Brockstein BE, List MA, Fung BB, Portugal L, Mittal BB, Pelzer H, Weichselbaum RR, Haraf DJ. Weekly carboplatin and paclitaxel followed by concomitant paclitaxel, fluorouracil, and hydroxyurea chemoradiotherapy: curative and organ-preserving therapy for advanced head and neck cancer. J Clin Oncol. 2003 Jan 15; 21(2):320-6. PMID: 12525525.
      Citations: 41     Fields:    Translation:Humans
    343. Gorski DH, Mauceri HJ, Salloum RM, Halpern A, Seetharam S, Weichselbaum RR. Prolonged treatment with angiostatin reduces metastatic burden during radiation therapy. Cancer Res. 2003 Jan 15; 63(2):308-11. PMID: 12543780.
      Citations: 5     Fields:    Translation:Animals
    344. Salloum RM, Saunders MP, Mauceri HJ, Hanna NN, Gorski DH, Posner MC, Stratford IJ, Weichselbaum RR. Dual induction of the Epo-Egr-TNF-alpha- plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay. Am Surg. 2003 Jan; 69(1):24-7. PMID: 12575775.
      Citations:    Fields:    Translation:HumansAnimalsCells
    345. Grdina DJ, Kataoka Y, Murley JS, Swedberg K, Lee JY, Hunter N, Weichselbaum RR, Milas L. Antimetastatic effectiveness of amifostine therapy following surgical removal of Sa-NH tumors in mice. Semin Oncol. 2002 Dec; 29(6 Suppl 19):22-8. PMID: 12577239.
      Citations: 5     Fields:    Translation:Animals
    346. Rasmussen H, Rasmussen C, Lempicki M, Durham R, Brough D, King CR, Weichselbaum R, Rasmussen H, Rasmussen C, Lempicki M, Durham R, Brough D, King CR, Weichselbaum R. TNFerade Biologic: preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene. Cancer Gene Ther. 2002 Nov; 9(11):951-7. PMID: 12386834.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    347. Weichselbaum RR, Kufe DW, Hellman S, Rasmussen HS, King CR, Fischer PH, Mauceri HJ, Weichselbaum RR, Kufe DW, Hellman S, Rasmussen HS, King CR, Fischer PH, Mauceri HJ. Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy. Lancet Oncol. 2002 Nov; 3(11):665-71. PMID: 12424068.
      Citations: 20     Fields:    Translation:Humans
    348. Ren X, Cao C, Zhu L, Yoshida K, Kharbanda S, Weichselbaum R, Kufe D. Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor. Cancer Biol Ther. 2002 Nov-Dec; 1(6):703-8. PMID: 12642697.
      Citations: 5     Fields:    Translation:HumansCells
    349. Mauceri HJ, Seetharam S, Beckett MA, Schumm LP, Koons A, Gupta VK, Park JO, Manan A, Lee JY, Montag AG, Kufe DW, Weichselbaum RR, Mauceri HJ, Seetharam S, Beckett MA, Schumm LP, Koons A, Gupta VK, Park JO, Manan A, Lee JY, Montag AG, Kufe DW, Weichselbaum RR. Angiostatin potentiates cyclophosphamide treatment of metastatic disease. Cancer Chemother Pharmacol. 2002 Nov; 50(5):412-8. PMID: 12439600.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    350. Advani SJ, Weichselbaum RR, Whitley RJ, Roizman B, Advani SJ, Weichselbaum RR, Whitley RJ, Roizman B. Friendly fire: redirecting herpes simplex virus-1 for therapeutic applications. Clin Microbiol Infect. 2002 Sep; 8(9):551-63. PMID: 12427216.
      Citations: 4     Fields:    Translation:HumansCells
    351. Hogg RP, Honorio S, Martinez A, Agathanggelou A, Dallol A, Fullwood P, Weichselbaum R, Kuo MJ, Maher ER, Latif F. Frequent 3p allele loss and epigenetic inactivation of the RASSF1A tumour suppressor gene from region 3p21.3 in head and neck squamous cell carcinoma. Eur J Cancer. 2002 Aug; 38(12):1585-92. PMID: 12142046.
      Citations: 36     Fields:    Translation:HumansCells
    352. Park JO, Lopez CA, Gupta VK, Brown CK, Mauceri HJ, Darga TE, Manan A, Hellman S, Posner MC, Kufe DW, Weichselbaum RR. Transcriptional control of viral gene therapy by cisplatin. J Clin Invest. 2002 Aug; 110(3):403-10. PMID: 12163460; PMCID: PMC151093.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    353. Gupta VK, Park JO, Jaskowiak NT, Mauceri HJ, Seetharam S, Weichselbaum RR, Posner MC, Gupta VK, Park JO, Jaskowiak NT, Mauceri HJ, Seetharam S, Weichselbaum RR, Posner MC. Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma. Ann Surg Oncol. 2002 Jun; 9(5):500-4. PMID: 12052763.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    354. Kataoka Y, Murley JS, Khodarev NN, Weichselbaum RR, Grdina DJ. Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine. Int J Radiat Oncol Biol Phys. 2002 May 01; 53(1):180-9. PMID: 12007958.
      Citations: 8     Fields:    Translation:HumansCells
    355. Mauceri HJ, Seetharam S, Beckett MA, Lee JY, Gupta VK, Gately S, Stack MS, Brown CK, Swedberg K, Kufe DW, Weichselbaum RR. Tumor production of angiostatin is enhanced after exposure to TNF-alpha. Int J Cancer. 2002 Feb 01; 97(4):410-5. PMID: 11802200.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    356. Khodarev NN, Yu J, Nodzenski E, Murley JS, Kataoka Y, Brown CK, Grdina DJ, Weichselbaum RR, Khodarev NN, Yu J, Nodzenski E, Murley JS, Kataoka Y, Brown CK, Grdina DJ, Weichselbaum RR. Method of RNA purification from endothelial cells for DNA array experiments. Biotechniques. 2002 Feb; 32(2):316, 318, 320. PMID: 11848408.
      Citations: 6     Fields:    Translation:HumansAnimals
    357. Grdina DJ, Kataoka Y, Murley JS, Hunter N, Weichselbaum RR, Milas L. Inhibition of spontaneous metastases formation by amifostine. Int J Cancer. 2002 Jan 10; 97(2):135-41. PMID: 11774255.
      Citations: 3     Fields:    Translation:Animals
    358. Chung SM, Advani SJ, Bradley JD, Kataoka Y, Vashistha K, Yan SY, Markert JM, Gillespie GY, Whitley RJ, Roizman B, Weichselbaum RR, Chung SM, Advani SJ, Bradley JD, Kataoka Y, Vashistha K, Yan SY, Markert JM, Gillespie GY, Whitley RJ, Roizman B, Weichselbaum RR. The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma. Gene Ther. 2002 Jan; 9(1):75-80. PMID: 11850725.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    359. Gupta VK, Jaskowiak NT, Beckett MA, Mauceri HJ, Grunstein J, Johnson RS, Calvin DA, Nodzenski E, Pejovic M, Kufe DW, Posner MC, Weichselbaum RR. Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance. Cancer J. 2002 Jan-Feb; 8(1):47-54. PMID: 11895203.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    360. Abdalla I, Ignacio L, Vaida F, Awan A, Jani A, Mamo C, Weichselbaum RR, Vijayakumar S. Evolution of toxicity after conformal radiotherapy for prostate cancer. Prostate Cancer Prostatic Dis. 2002; 5(4):296-303. PMID: 12627215.
      Citations:    Fields:    Translation:HumansPHPublic Health
    361. Jani AB, Vaida F, Hanks G, Asbell S, Sartor O, Moul JW, Roach M, Brachman D, Kalokhe U, Muller-Runkel R, Ray P, Ignacio L, Awan A, Weichselbaum RR, Vijayakumar S. Changing face and different countenances of prostate cancer: racial and geographic differences in prostate-specific antigen (PSA), stage, and grade trends in the PSA era. Int J Cancer. 2001 Dec 20; 96(6):363-71. PMID: 11745507.
      Citations: 12     Fields:    Translation:Humans
    362. Skelly CL, Curi MA, Meyerson SL, Woo DH, Hari D, Vosicky JE, Advani SJ, Mauceri HJ, Glagov S, Roizman B, Weichselbaum RR, Schwartz LB, Skelly CL, Curi MA, Meyerson SL, Woo DH, Hari D, Vosicky JE, Advani SJ, Mauceri HJ, Glagov S, Roizman B, Weichselbaum RR, Schwartz LB. Prevention of restenosis by a herpes simplex virus mutant capable of controlled long-term expression in vascular tissue in vivo. Gene Ther. 2001 Dec; 8(24):1840-6. PMID: 11821937.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    363. Yin L, Ohno T, Weichselbaum R, Kharbanda S, Kufe D. The novel isocoumarin 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid (NM-3) induces lethality of human carcinoma cells by generation of reactive oxygen species. Mol Cancer Ther. 2001 Nov; 1(1):43-8. PMID: 12467237.
      Citations: 4     Fields:    Translation:HumansCells
    364. Advani SJ, Weichselbaum RR, Roizman B, Advani SJ, Weichselbaum RR, Roizman B. cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor. J Virol. 2001 Nov; 75(21):10326-33. PMID: 11581401; PMCID: PMC114607.
      Citations: 22     Fields:    Translation:HumansCells
    365. Khodarev NN, Park JO, Yu J, Gupta N, Nodzenski E, Roizman B, Weichselbaum RR, Khodarev NN, Park JO, Yu J, Gupta N, Nodzenski E, Roizman B, Weichselbaum RR. Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12665-70. PMID: 11675498; PMCID: PMC60111.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    366. Chmura SJ, Gupta N, Advani SJ, Kufe DW, Weichselbaum RR, Chmura SJ, Gupta N, Advani SJ, Kufe DW, Weichselbaum RR. Prospects for viral-based strategies enhancing the anti-tumor effects of ionizing radiation. Semin Radiat Oncol. 2001 Oct; 11(4):338-45. PMID: 11677658.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    367. Mauceri HJ, Seetharam S, Salloum RM, Vokes EE, Weichselbaum RR. Treatment of head and neck and esophageal xenografts employing Alimta and concurrent ionizing radiation. Int J Oncol. 2001 Oct; 19(4):833-5. PMID: 11562763.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    368. Gupta N, Wang H, McLeod TL, Naus CC, Kyurkchiev S, Advani S, Yu J, Perbal B, Weichselbaum RR, Gupta N, Wang H, McLeod TL, Naus CC, Kyurkchiev S, Advani S, Yu J, Perbal B, Weichselbaum RR. Inhibition of glioma cell growth and tumorigenic potential by CCN3 (NOV). Mol Pathol. 2001 Oct; 54(5):293-9. PMID: 11577170; PMCID: PMC1187085.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    369. Advani SJ, Hagglund R, Weichselbaum RR, Roizman B, Advani SJ, Hagglund R, Weichselbaum RR, Roizman B. Posttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localize. J Virol. 2001 Sep; 75(17):7904-12. PMID: 11483735; PMCID: PMC115034.
      Citations: 22     Fields:    Translation:HumansCells
    370. Gasior SL, Olivares H, Ear U, Hari DM, Weichselbaum R, Bishop DK. Assembly of RecA-like recombinases: distinct roles for mediator proteins in mitosis and meiosis. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8411-8. PMID: 11459983; PMCID: PMC37451.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    371. Sharma A, Mani S, Hanna N, Guha C, Vikram B, Weichselbaum RR, Sparano J, Sood B, Lee D, Regine W, Muhodin M, Valentino J, Herman J, Desimone P, Arnold S, Carrico J, Rockich AK, Warner-Carpenter J, Barton-Baxter M, Sharma A, Mani S, Hanna N, Guha C, Vikram B, Weichselbaum RR, Sparano J, Sood B, Lee D, Regine W, Muhodin M, Valentino J, Herman J, Desimone P, Arnold S, Carrico J, Rockich AK, Warner-Carpenter J, Barton-Baxter M. Clinical protocol. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade Biologic) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors. Hum Gene Ther. 2001 Jun 10; 12(9):1109-31. PMID: 11399232.
      Citations: 5     Fields:    Translation:Humans
    372. Gupta N, Nodzenski E, Khodarev NN, Yu J, Khorasani L, Beckett MA, Kufe DW, Weichselbaum RR. Angiostatin effects on endothelial cells mediated by ceramide and RhoA. EMBO Rep. 2001 Jun; 2(6):536-40. PMID: 11415988; PMCID: PMC1083909.
      Citations: 12     Fields:    Translation:HumansCells
    373. Kies MS, Haraf DJ, Rosen F, Stenson K, List M, Brockstein B, Chung T, Mittal BB, Pelzer H, Portugal L, Rademaker A, Weichselbaum R, Vokes EE. Concomitant infusional paclitaxel and fluorouracil, oral hydroxyurea, and hyperfractionated radiation for locally advanced squamous head and neck cancer. J Clin Oncol. 2001 Apr 01; 19(7):1961-9. PMID: 11283128.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    374. Mantz CA, Vokes EE, Kies MS, Mittal B, Witt ME, List MA, Weichselbaum RR, Haraf DJ. Sequential induction chemotherapy and concomitant chemoradiotherapy in the management of locoregionally advanced laryngeal cancer. Ann Oncol. 2001 Mar; 12(3):343-7. PMID: 11332146.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    375. Mantz CA, Vokes EE, Stenson K, Kies MS, Mittal B, Witt ME, List MA, Weichselbaum RR, Haraf DJ. Induction chemotherapy followed by concomitant chemoradiotherapy in the treatment of locoregionally advanced oropharyngeal cancer. Cancer J. 2001 Mar-Apr; 7(2):140-8. PMID: 11324767.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    376. Ito Y, Pandey P, Sathyanarayana P, Ling P, Rana A, Weichselbaum R, Tan TH, Kufe D, Kharbanda S. Interaction of hematopoietic progenitor kinase 1 and c-Abl tyrosine kinase in response to genotoxic stress. J Biol Chem. 2001 May 25; 276(21):18130-8. PMID: 11278340.
      Citations: 1     Fields:    Translation:HumansCells
    377. Connell PP, Ignacio L, Haraf D, Awan AM, Halpern H, Abdalla I, Nautiyal J, Jani AB, Weichselbaum RR, Vijayakumar S. Equivalent racial outcome after conformal radiotherapy for prostate cancer: a single departmental experience. J Clin Oncol. 2001 Jan 01; 19(1):54-61. PMID: 11134195.
      Citations: 5     Fields:    Translation:Humans
    378. Weichselbaum RR, Kufe DW, Advani SJ, Roizman B. Molecular targeting of gene therapy and radiotherapy. Acta Oncol. 2001; 40(6):735-8. PMID: 11765068.
      Citations: 12     Fields:    Translation:HumansCells
    379. Salloum RM, Jaskowiak NT, Mauceri HJ, Seetharam S, Beckett MA, Koons AM, Hari DM, Gupta VK, Reimer C, Kalluri R, Posner MC, Hellman S, Kufe DW, Weichselbaum RR. NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity. Cancer Res. 2000 Dec 15; 60(24):6958-63. PMID: 11156396.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    380. Pelizzari CA, Khodarev NN, Gupta N, Calvin DP, Weichselbaum RR. Quantitative analysis of DNA array autoradiographs. Nucleic Acids Res. 2000 Nov 15; 28(22):4577-81. PMID: 11071949; PMCID: PMC113872.
      Citations: 1     Fields:    Translation:HumansCells
    381. Advani SJ, Weichselbaum RR, Roizman B. The role of cdc2 in the expression of herpes simplex virus genes. Proc Natl Acad Sci U S A. 2000 Sep 26; 97(20):10996-1001. PMID: 10995483; PMCID: PMC27137.
      Citations: 35     Fields:    Translation:HumansCells
    382. Hanna NN, Seetharam S, Mauceri HJ, Beckett MA, Jaskowiak NT, Salloum RM, Hari D, Dhanabal M, Ramchandran R, Kalluri R, Sukhatme VP, Kufe DW, Weichselbaum RR. Antitumor interaction of short-course endostatin and ionizing radiation. Cancer J. 2000 Sep-Oct; 6(5):287-93. PMID: 11079167.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    383. Advani SJ, Weichselbaum RR, Roizman B. E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1. J Virol. 2000 Sep; 74(17):7842-50. PMID: 10933691; PMCID: PMC112314.
      Citations: 16     Fields:    Translation:HumansCells
    384. Pandey P, Saleh A, Nakazawa A, Kumar S, Srinivasula SM, Kumar V, Weichselbaum R, Nalin C, Alnemri ES, Kufe D, Kharbanda S. Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90. EMBO J. 2000 Aug 15; 19(16):4310-22. PMID: 10944114; PMCID: PMC302037.
      Citations: 136     Fields:    Translation:HumansCells
    385. Bhattacharyya A, Ear US, Koller BH, Weichselbaum RR, Bishop DK. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. J Biol Chem. 2000 Aug 04; 275(31):23899-903. PMID: 10843985.
      Citations: 221     Fields:    Translation:AnimalsCells
    386. Schwartz JL, Jordan R, Kaufmann WK, Rasey J, Russell KJ, Weichselbaum RR. Evidence for the expression of radiation-induced potentially lethal damage being a p53-dependent process. Int J Radiat Biol. 2000 Aug; 76(8):1037-43. PMID: 10947116.
      Citations: 3     Fields:    Translation:HumansCells
    387. Yoshida K, Weichselbaum R, Kharbanda S, Kufe D. Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage. Mol Cell Biol. 2000 Aug; 20(15):5370-80. PMID: 10891478; PMCID: PMC85989.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    388. Stenson KM, Haraf DJ, Pelzer H, Recant W, Kies MS, Weichselbaum RR, Vokes EE. The role of cervical lymphadenectomy after aggressive concomitant chemoradiotherapy: the feasibility of selective neck dissection. Arch Otolaryngol Head Neck Surg. 2000 Aug; 126(8):950-6. PMID: 10922226.
      Citations: 25     Fields:    Translation:Humans
    389. Hannig J, Zhang D, Canaday DJ, Beckett MA, Astumian RD, Weichselbaum RR, Lee RC. Surfactant sealing of membranes permeabilized by ionizing radiation. Radiat Res. 2000 Aug; 154(2):171-7. PMID: 10931689.
      Citations: 18     Fields:    Translation:AnimalsCellsPHPublic Health
    390. Kharbanda S, Pandey P, Yamauchi T, Kumar S, Kaneki M, Kumar V, Bharti A, Yuan ZM, Ghanem L, Rana A, Weichselbaum R, Johnson G, Kufe D. Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage. Mol Cell Biol. 2000 Jul; 20(14):4979-89. PMID: 10866655; PMCID: PMC85948.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    391. Sun X, Majumder P, Shioya H, Wu F, Kumar S, Weichselbaum R, Kharbanda S, Kufe D. Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species. J Biol Chem. 2000 Jun 09; 275(23):17237-40. PMID: 10770918.
      Citations: 52     Fields:    Translation:AnimalsCells
    392. Hari D, Beckett MA, Sukhatme VP, Dhanabal M, Nodzenski E, Lu H, Mauceri HJ, Kufe DW, Weichselbaum RR. Angiostatin induces mitotic cell death of proliferating endothelial cells. Mol Cell Biol Res Commun. 2000 May; 3(5):277-82. PMID: 10964751.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    393. Colorado PC, Torre A, Kamphaus G, Maeshima Y, Hopfer H, Takahashi K, Volk R, Zamborsky ED, Herman S, Sarkar PK, Ericksen MB, Dhanabal M, Simons M, Post M, Kufe DW, Weichselbaum RR, Sukhatme VP, Kalluri R. Anti-angiogenic cues from vascular basement membrane collagen. Cancer Res. 2000 May 01; 60(9):2520-6. PMID: 10811134.
      Citations: 131     Fields:    Translation:HumansAnimalsCells
    394. Kumar V, Sabatini D, Pandey P, Gingras AC, Majumder PK, Kumar M, Yuan ZM, Carmichael G, Weichselbaum R, Sonenberg N, Kufe D, Kharbanda S. Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase. J Biol Chem. 2000 Apr 14; 275(15):10779-87. PMID: 10753870.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    395. Pandey P, Farber R, Nakazawa A, Kumar S, Bharti A, Nalin C, Weichselbaum R, Kufe D, Kharbanda S. Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3. Oncogene. 2000 Apr 13; 19(16):1975-81. PMID: 10803458.
      Citations: 89     Fields:    Translation:HumansCells
    396. Vokes EE, Kies MS, Haraf DJ, Stenson K, List M, Humerickhouse R, Dolan ME, Pelzer H, Sulzen L, Witt ME, Hsieh YC, Mittal BB, Weichselbaum RR. Concomitant chemoradiotherapy as primary therapy for locoregionally advanced head and neck cancer. J Clin Oncol. 2000 Apr; 18(8):1652-61. PMID: 10764425.
      Citations: 44     Fields:    Translation:HumansCTClinical Trials
    397. Chmura SJ, Nodzenski E, Kharbanda S, Pandey P, Quintans J, Kufe DW, Weichselbaum RR. Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis. Mol Pharmacol. 2000 Apr; 57(4):792-6. PMID: 10727527.
      Citations: 11     Fields:    Translation:AnimalsCells
    398. Fortunato JE, Mauceri HJ, Kocharyan H, Song RH, Salloum R, Vosicky J, Swedberg K, Malik S, Abusharif F, Glagov S, Weichselbaum RR, Bassiouny HS. Gene therapy enhances the antiproliferative effect of radiation in intimal hyperplasia. J Surg Res. 2000 Apr; 89(2):155-62. PMID: 10729244.
      Citations:    Fields:    Translation:Animals
    399. Stenson KM, MacCracken E, List M, Haraf DJ, Brockstein B, Weichselbaum R, Vokes EE. Swallowing function in patients with head and neck cancer prior to treatment. Arch Otolaryngol Head Neck Surg. 2000 Mar; 126(3):371-7. PMID: 10722011.
      Citations: 36     Fields:    Translation:Humans
    400. Chmura SJ, Dolan ME, Cha A, Mauceri HJ, Kufe DW, Weichselbaum RR. In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo. Clin Cancer Res. 2000 Feb; 6(2):737-42. PMID: 10690561.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    401. Kharbanda S, Saxena S, Yoshida K, Pandey P, Kaneki M, Wang Q, Cheng K, Chen YN, Campbell A, Sudha T, Yuan ZM, Narula J, Weichselbaum R, Nalin C, Kufe D. Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage. J Biol Chem. 2000 Jan 07; 275(1):322-7. PMID: 10617621.
      Citations: 121     Fields:    Translation:HumansCells
    402. Advani SJ, Brandimarti R, Weichselbaum RR, Roizman B. The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes. J Virol. 2000 Jan; 74(1):8-15. PMID: 10590085; PMCID: PMC111507.
      Citations: 51     Fields:    Translation:Cells
    403. Markert JM, Gillespie GY, Weichselbaum RR, Roizman B, Whitley RJ. Genetically engineered HSV in the treatment of glioma: a review. Rev Med Virol. 2000 Jan-Feb; 10(1):17-30. PMID: 10654002.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    404. Connell PP, Ignacio L, McBride RB, Weichselbaum RR, Vijayakumar S. Caution in interpreting biochemical control rates after treatment of prostate cancer: length of follow-up influences results. Urology. 1999 Nov; 54(5):875-9. PMID: 10565750.
      Citations: 1     Fields:    Translation:Humans
    405. Terry MA, Hannig J, Carrillo CS, Beckett MA, Weichselbaum RR, Lee RC. Oxidative cell membrane alteration. Evidence for surfactant-mediated sealing. Ann N Y Acad Sci. 1999 Oct 30; 888:274-84. PMID: 10842639.
      Citations: 5     Fields:    Translation:HumansCells
    406. Khodarev NN, Advani SJ, Gupta N, Roizman B, Weichselbaum RR. Accumulation of specific RNAs encoding transcriptional factors and stress response proteins against a background of severe depletion of cellular RNAs in cells infected with herpes simplex virus 1. Proc Natl Acad Sci U S A. 1999 Oct 12; 96(21):12062-7. PMID: 10518576; PMCID: PMC18412.
      Citations: 23     Fields:    Translation:HumansCells
    407. Yuan ZM, Huang Y, Ishiko T, Nakada S, Utsugisawa T, Shioya H, Utsugisawa Y, Shi Y, Weichselbaum R, Kufe D. Function for p300 and not CBP in the apoptotic response to DNA damage. Oncogene. 1999 Oct 07; 18(41):5714-7. PMID: 10523850.
      Citations: 21     Fields:    Translation:HumansCells
    408. Morrison C, Shinohara A, Sonoda E, Yamaguchi-Iwai Y, Takata M, Weichselbaum RR, Takeda S. The essential functions of human Rad51 are independent of ATP hydrolysis. Mol Cell Biol. 1999 Oct; 19(10):6891-7. PMID: 10490626; PMCID: PMC84684.
      Citations: 46     Fields:    Translation:HumansCells
    409. Seetharam S, Staba MJ, Schumm LP, Schreiber K, Schreiber H, Kufe DW, Weichselbaum RR. Enhanced eradication of local and distant tumors by genetically produced interleukin-12 and radiation. Int J Oncol. 1999 Oct; 15(4):769-73. PMID: 10493960.
      Citations: 19     Fields:    Translation:AnimalsCells
    410. Jani AB, Chen MH, Vaida F, Ignacio L, Awan A, Weichselbaum RR, Vijayakumar S. PSA-based outcome analysis after radiation therapy for prostate cancer: a new definition of biochemical failure after intervention. Urology. 1999 Oct; 54(4):700-5. PMID: 10510931.
      Citations: 2     Fields:    Translation:Humans
    411. Gorski DH, Beckett MA, Jaskowiak NT, Calvin DP, Mauceri HJ, Salloum RM, Seetharam S, Koons A, Hari DM, Kufe DW, Weichselbaum RR. Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res. 1999 Jul 15; 59(14):3374-8. PMID: 10416597.
      Citations: 240     Fields:    Translation:HumansAnimalsCells
    412. Lee MM, Vokes EE, Rosen A, Witt ME, Weichselbaum RR, Haraf DJ. Multimodality therapy in advanced paranasal sinus carcinoma: superior long-term results. Cancer J Sci Am. 1999 Jul-Aug; 5(4):219-23. PMID: 10439167.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    413. Mantz CA, Nautiyal J, Awan A, Kopnick M, Ray P, Kandel G, Niederberger C, Ignacio L, Dawson E, Fields R, Weichselbaum R, Vijayakumar S. Potency preservation following conformal radiotherapy for localized prostate cancer: impact of neoadjuvant androgen blockade, treatment technique, and patient-related factors. Cancer J Sci Am. 1999 Jul-Aug; 5(4):230-6. PMID: 10439169.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    414. Yuan ZM, Shioya H, Ishiko T, Sun X, Gu J, Huang YY, Lu H, Kharbanda S, Weichselbaum R, Kufe D. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature. 1999 Jun 24; 399(6738):814-7. PMID: 10391251.
      Citations: 168     Fields:    Translation:AnimalsCells
    415. Lee JS, Jani AB, Pelizzari CA, Haraf DJ, Vokes EE, Weichselbaum RR, Chen GT. Volumetric visualization of head and neck CT data for treatment planning. Int J Radiat Oncol Biol Phys. 1999 Jun 01; 44(3):693-703. PMID: 10348301.
      Citations: 1     Fields:    Translation:Humans
    416. Bradley JD, Kataoka Y, Advani S, Chung SM, Arani RB, Gillespie GY, Whitley RJ, Markert JM, Roizman B, Weichselbaum RR. Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus. Clin Cancer Res. 1999 Jun; 5(6):1517-22. PMID: 10389941.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    417. Advani SJ, Chung SM, Yan SY, Gillespie GY, Markert JM, Whitley RJ, Roizman B, Weichselbaum RR. Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors. Cancer Res. 1999 May 01; 59(9):2055-8. PMID: 10232586.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    418. Huang Y, Nakada S, Ishiko T, Utsugisawa T, Datta R, Kharbanda S, Yoshida K, Talanian RV, Weichselbaum R, Kufe D, Yuan ZM. Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage. Mol Cell Biol. 1999 Apr; 19(4):2986-97. PMID: 10082566; PMCID: PMC84093.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    419. Vokes EE, Haraf DJ, Brockstein BE, Weichselbaum RR. Paclitaxel, 5-fluorouracil, hydroxyurea, and concomitant radiation therapy for poor-prognosis head and neck cancer. Semin Radiat Oncol. 1999 Apr; 9(2 Suppl 1):70-6. PMID: 10210543.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    420. Hannig J, Yu J, Beckett M, Weichselbaum R, Lee RC. Poloxamine 1107 sealing of radiopermeabilized erythrocyte membranes. Int J Radiat Biol. 1999 Mar; 75(3):379-85. PMID: 10203188.
      Citations: 6     Fields:    Translation:HumansCells
    421. Mauceri HJ, Hanna NN, Staba MJ, Beckett MA, Kufe DW, Weichselbaum RR. Radiation-inducible gene therapy. C R Acad Sci III. 1999 Feb-Mar; 322(2-3):225-8. PMID: 10196676.
      Citations:    Fields:    Translation:HumansCells
    422. Schwartz JL, Murnane J, Weichselbaum RR. The contribution of DNA ploidy to radiation sensitivity in human tumour cell lines. Br J Cancer. 1999 Feb; 79(5-6):744-7. PMID: 10070863; PMCID: PMC2362676.
      Citations: 5     Fields:    Translation:HumansCells
    423. Haraf DJ, Kies M, Rademaker AW, Stenson K, Mittal B, Pelzer H, Wenig B, Witt ME, Sulzen L, Weichselbaum RR, Vokes EE. Radiation therapy with concomitant hydroxyurea and fluorouracil in stage II and III head and neck cancer. J Clin Oncol. 1999 Feb; 17(2):638-44. PMID: 10080609.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    424. Yuan ZM, Huang Y, Ishiko T, Nakada S, Utsugisawa T, Shioya H, Utsugisawa Y, Yokoyama K, Weichselbaum R, Shi Y, Kufe D. Role for p300 in stabilization of p53 in the response to DNA damage. J Biol Chem. 1999 Jan 22; 274(4):1883-6. PMID: 9890940.
      Citations: 37     Fields:    Translation:HumansCells
    425. Chmura SJ, Advani SJ, Kufe DW, Weichselbaum RR. Strategies for enhancing viral-based gene therapy using ionizing radiation. Radiat Oncol Investig. 1999; 7(5):261-9. PMID: 10580895.
      Citations: 1     Fields:    Translation:HumansCells
    426. Lee MM, Heimann R, Powers C, Weichselbaum RR, Chen LM. Efficacy of Breast Conservation Therapy in Early Stage Bilateral Breast Cancer. Breast J. 1999 Jan; 5(1):36-41. PMID: 11348254.
      Citations: 6     Fields:    
    427. Kharbanda S, Yuan ZM, Weichselbaum R, Kufe D. Determination of cell fate by c-Abl activation in the response to DNA damage. Oncogene. 1998 Dec 24; 17(25):3309-18. PMID: 9916993.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    428. Gorski DH, Mauceri HJ, Salloum RM, Gately S, Hellman S, Beckett MA, Sukhatme VP, Soff GA, Kufe DW, Weichselbaum RR. Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin. Cancer Res. 1998 Dec 15; 58(24):5686-9. PMID: 9865723.
      Citations: 28     Fields:    Translation:AnimalsCells
    429. Bharti A, Kraeft SK, Gounder M, Pandey P, Jin S, Yuan ZM, Lees-Miller SP, Weichselbaum R, Weaver D, Chen LB, Kufe D, Kharbanda S. Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis. Mol Cell Biol. 1998 Nov; 18(11):6719-28. PMID: 9774685; PMCID: PMC109255.
      Citations: 52     Fields:    Translation:HumansCells
    430. Chung TD, Mauceri HJ, Hallahan DE, Yu JJ, Chung S, Grdina WL, Yajnik S, Kufe DW, Weichselbaum RR. Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer. Cancer Gene Ther. 1998 Nov-Dec; 5(6):344-9. PMID: 9917088.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    431. Kumar S, Pandey P, Bharti A, Jin S, Weichselbaum R, Weaver D, Kufe D, Kharbanda S. Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase. J Biol Chem. 1998 Oct 02; 273(40):25654-8. PMID: 9748231.
      Citations: 8     Fields:    Translation:HumansCells
    432. Bishop DK, Ear U, Bhattacharyya A, Calderone C, Beckett M, Weichselbaum RR, Shinohara A. Xrcc3 is required for assembly of Rad51 complexes in vivo. J Biol Chem. 1998 Aug 21; 273(34):21482-8. PMID: 9705276.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    433. Seetharam S, Nodzenski E, Beckett MA, Heimann R, Cha A, Margulies I, Pastan I, Kufe DW, Weichselbaum RR. Modulation of apoptotic response of a radiation-resistant human carcinoma by Pseudomonas exotoxin-chimeric protein. Cancer Res. 1998 Aug 01; 58(15):3215-20. PMID: 9699644.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    434. Kies MS, Haraf DJ, Athanasiadis I, Kozloff M, Mittal B, Pelzer H, Rademaker AW, Wenig B, Weichselbaum RR, Vokes EE. Induction chemotherapy followed by concurrent chemoradiation for advanced head and neck cancer: improved disease control and survival. J Clin Oncol. 1998 Aug; 16(8):2715-21. PMID: 9704722.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    435. Mauceri HJ, Hanna NN, Beckett MA, Gorski DH, Staba MJ, Stellato KA, Bigelow K, Heimann R, Gately S, Dhanabal M, Soff GA, Sukhatme VP, Kufe DW, Weichselbaum RR. Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature. 1998 Jul 16; 394(6690):287-91. PMID: 9685160.
      Citations: 101     Fields:    Translation:HumansAnimalsCells
    436. Kharbanda S, Pandey P, Morris PL, Whang Y, Xu Y, Sawant S, Zhu LJ, Kumar N, Yuan ZM, Weichselbaum R, Sawyers CL, Pandita TK, Kufe D. Functional role for the c-Abl tyrosine kinase in meiosis I. Oncogene. 1998 Apr 09; 16(14):1773-7. PMID: 9583675.
      Citations: 9     Fields:    Translation:AnimalsCells
    437. Yuan ZM, Utsugisawa T, Ishiko T, Nakada S, Huang Y, Kharbanda S, Weichselbaum R, Kufe D. Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation. Oncogene. 1998 Apr 02; 16(13):1643-8. PMID: 9582011.
      Citations: 32     Fields:    Translation:HumansCells
    438. Staba MJ, Mauceri HJ, Kufe DW, Hallahan DE, Weichselbaum RR. Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft. Gene Ther. 1998 Mar; 5(3):293-300. PMID: 9614548.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    439. Yuan ZM, Huang Y, Ishiko T, Nakada S, Utsugisawa T, Kharbanda S, Wang R, Sung P, Shinohara A, Weichselbaum R, Kufe D. Regulation of Rad51 function by c-Abl in response to DNA damage. J Biol Chem. 1998 Feb 13; 273(7):3799-802. PMID: 9461559.
      Citations: 61     Fields: