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Jill De Jong

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentPediatrics-Hematology and Oncology
AddressChicago IL 60637
Phone+1 (773) 702-2646
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    Collapse Overview 
    Collapse overview
    Dr. de Jong treats children with all types of cancer and blood diseases. She is the Director of Pediatric Hematology and has specialized expertise in bone marrow failure, leukemia, autoimmune blood diseases (such as autoimmune hemolytic anemia, autoimmune neutropenia, immune thrombocytopenia purpura and Evans syndrome), hemoglobinopathies (such as thalassemia and sickle cell disease), and bleeding and clotting disorders.

    Her research focuses on hematopoietic stem cells and genetic risks for hematologic malignancy. She is co-director of the Pediatric Cancer Genetic Risk clinic and the director of the Pediatric Bone Marrow Failure clinic.

    Dr. de Jong has also invested her time in education, serving as the Director of Pediatric Fellowship Training for the Department of Pediatrics until 2020, and she is currently the Program Director for the Pediatric Hematology-Oncology Fellowship.


    Collapse Biography 
    Collapse education and training
    Dana Farber Cancer Institute and Boston Children's Hospital, Boston, MAFellowship06/2005Pediatric Hematology-Oncology
    Boston Children's Hospital, Boston, MAResidency06/2002Pediatrics
    University of Wisconsin, Madison, WIMD05/1999Medicine
    University of Wisconsin, Madison, WIPhD05/1997Cancer Biology
    University of Chicago, Chicago, ILAB06/1990Biology
    Collapse awards and honors
    2013 - nowRegional Top Doctor, Pediatric Hematology-Oncology, Castle Connolly
    2010Pritzker Scholar Award, University of Chicago
    1998Alpha Omega Alpha, Medical Honor Society, University of Wisconsin
    1990Phi Beta Kappa, University of Chicago

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Cohen EL, Millikan SE, Morocco PC, de Jong JLO. Hemorrhagic Shock after Neonatal Circumcision: Severe Congenital Factor XIII Deficiency. Case Rep Pediatr. 2021; 2021:5550199. PMID: 34007504.
      View in: PubMed
    2. DiNapoli SE, Martinez-McFaline R, Gribbin CK, Wrighton PJ, Balgobin CA, Nelson I, Leonard A, Maskin CR, Shwartz A, Quenzer ED, Mailhiot D, Kao C, McConnell SC, de Jong JLO, Goessling W, Houvras Y. Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair. Nucleic Acids Res. 2020 04 17; 48(7):e38. PMID: 32064511.
      View in: PubMed
    3. de Jong JLO. Splicing up hematopoietic development. Blood. 2019 02 21; 133(8):770-771. PMID: 30792220.
      View in: PubMed
    4. Baeten JT, Waarts MR, Pruitt MM, Chan WC, Andrade J, de Jong JLO. The side population enriches for leukemia-propagating cell activity and Wnt pathway expression in zebrafish acute lymphoblastic leukemia. Haematologica. 2019 07; 104(7):1388-1395. PMID: 30630989.
      View in: PubMed
    5. Baeten JT, de Jong JLO. Genetic Models of Leukemia in Zebrafish. Front Cell Dev Biol. 2018; 6:115. PMID: 30294597.
      View in: PubMed
    6. Esteban YM, de Jong JLO, Tesher MS. An Overview of Hemophagocytic Lymphohistiocytosis. Pediatr Ann. 2017 Aug 01; 46(8):e309-e313. PMID: 28806468.
      View in: PubMed
    7. Pruitt MM, Marin W, Waarts MR, de Jong JLO. Isolation of the Side Population in Myc-induced T-cell Acute Lymphoblastic Leukemia in Zebrafish. J Vis Exp. 2017 05 04; (123). PMID: 28518092.
      View in: PubMed
    8. Villanueva G, de Jong JL, McNeer JL. Intravenous Immunoglobulin in the Treatment of Hematologic Disorders in Pediatrics. Pediatr Ann. 2017 Jan 01; 46(1):e13-e18. PMID: 28079913.
      View in: PubMed
    9. McConnell SC, Hernandez KM, Wcisel DJ, Kettleborough RN, Stemple DL, Yoder JA, Andrade J, de Jong JL. Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution. Proc Natl Acad Sci U S A. 2016 08 23; 113(34):E5014-23. PMID: 27493218.
      View in: PubMed
    10. Nassin ML, Lapping-Carr G, de Jong JL. Anemia in the Neonate: The Differential Diagnosis and Treatment. Pediatr Ann. 2015 Jul; 44(7):e159-63. PMID: 26171704.
      View in: PubMed
    11. Yang XH, Li M, Wang B, Zhu W, Desgardin A, Onel K, de Jong J, Chen J, Chen L, Cunningham JM. Systematic computation with functional gene-sets among leukemic and hematopoietic stem cells reveals a favorable prognostic signature for acute myeloid leukemia. BMC Bioinformatics. 2015 Mar 24; 16:97. PMID: 25887548.
      View in: PubMed
    12. Ansari DO, Lapping-Carr G, Alikhan M, Tsoukas ML, Stein SL, de Jong JL. A neonate with a vesiculopustular rash. Pediatr Ann. 2015 Jan; 44(1):e1-5. PMID: 25621627.
      View in: PubMed
    13. Dirscherl H, McConnell SC, Yoder JA, de Jong JL. The MHC class I genes of zebrafish. Dev Comp Immunol. 2014 Sep; 46(1):11-23. PMID: 24631581.
      View in: PubMed
    14. McConnell SC, Restaino AC, de Jong JL. Multiple divergent haplotypes express completely distinct sets of class I MHC genes in zebrafish. Immunogenetics. 2014 Mar; 66(3):199-213. PMID: 24291825.
      View in: PubMed
    15. de Jong JL, Zon LI. Histocompatibility and hematopoietic transplantation in the zebrafish. Adv Hematol. 2012; 2012:282318. PMID: 22778744.
      View in: PubMed
    16. Ganis JJ, Hsia N, Trompouki E, de Jong JL, DiBiase A, Lambert JS, Jia Z, Sabo PJ, Weaver M, Sandstrom R, Stamatoyannopoulos JA, Zhou Y, Zon LI. Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Dev Biol. 2012 Jun 15; 366(2):185-94. PMID: 22537494.
      View in: PubMed
    17. de Jong JL, Burns CE, Chen AT, Pugach E, Mayhall EA, Smith AC, Feldman HA, Zhou Y, Zon LI. Characterization of immune-matched hematopoietic transplantation in zebrafish. Blood. 2011 Apr 21; 117(16):4234-42. PMID: 21346254.
      View in: PubMed
    18. de Jong JL, Davidson AJ, Wang Y, Palis J, Opara P, Pugach E, Daley GQ, Zon LI. Interaction of retinoic acid and scl controls primitive blood development. Blood. 2010 Jul 15; 116(2):201-9. PMID: 20410509.
      View in: PubMed
    19. Paik EJ, de Jong JL, Pugach E, Opara P, Zon LI. A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis. Zebrafish. 2010 Mar; 7(1):61-8. PMID: 20415644.
      View in: PubMed
    20. Smith AC, Raimondi AR, Salthouse CD, Ignatius MS, Blackburn JS, Mizgirev IV, Storer NY, de Jong JL, Chen AT, Zhou Y, Revskoy S, Zon LI, Langenau DM. High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. Blood. 2010 Apr 22; 115(16):3296-303. PMID: 20056790.
      View in: PubMed
    21. Gordon DJ, Sloan SR, de Jong JL. A pediatric case series of acute hemolysis after administration of intravenous immunoglobulin. Am J Hematol. 2009 Nov; 84(11):771-2. PMID: 19806664.
      View in: PubMed
    22. Bennett CM, de Jong JL, Neufeld EJ. Targeted ITP strategies: do they elucidate the biology of ITP and related disorders? Pediatr Blood Cancer. 2006 Oct 15; 47(5 Suppl):706-9. PMID: 16933263.
      View in: PubMed
    23. de Jong JL, Zon LI. Use of the zebrafish system to study primitive and definitive hematopoiesis. Annu Rev Genet. 2005; 39:481-501. PMID: 16285869.
      View in: PubMed
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