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Nan-Sheng Li

InstitutionUniversity of Chicago
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li NS, Liang W, Piccirilli JA, Tang WJ. Reinvestigating the synthesis and efficacy of small benzimidazole derivatives as presequence protease enhancers. Eur J Med Chem. 2019 Dec 15; 184:111746. PMID: 31610373; PMCID: PMC6874713.
      Citations: 2     Fields:    Translation:HumansCells
    2. Shao Y, Huang H, Qin D, Li NS, Koide A, Staley JP, Koide S, Kossiakoff AA, Piccirilli JA. Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment. J Mol Biol. 2016 10 09; 428(20):4100-4114. PMID: 27593161; PMCID: PMC5178103.
      Citations: 6     Fields:    Translation:Cells
    3. Li NC, Fan J, Papadopoulos V. Sterol Carrier Protein-2, a Nonspecific Lipid-Transfer Protein, in Intracellular Cholesterol Trafficking in Testicular Leydig Cells. PLoS One. 2016; 11(2):e0149728. PMID: 26901662; PMCID: PMC4762939.
      Citations: 9     Fields:    Translation:AnimalsCells
    4. Roy S, Ly D, Castro CD, Li NS, Hawk AJ, Altman JD, Meredith SC, Piccirilli JA, Moody DB, Adams EJ. Molecular Analysis of Lipid-Reactive Vd1 ?d T Cells Identified by CD1c Tetramers. J Immunol. 2016 Feb 15; 196(4):1933-42. PMID: 26755823; PMCID: PMC4744554.
      Citations: 47     Fields:    Translation:HumansCells
    5. Lu YC, Nazarko OV, Sando R, Salzman GS, Li NS, Südhof TC, Araç D. Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. Structure. 2015 Sep 01; 23(9):1678-1691. PMID: 26235030; PMCID: PMC4851429.
      Citations: 67     Fields:    Translation:HumansCells
    6. DasGupta S, Shelke SA, Li NS, Piccirilli JA. Spinach RNA aptamer detects lead(II) with high selectivity. Chem Commun (Camb). 2015 May 28; 51(43):9034-7. PMID: 25940073; PMCID: PMC4755583.
      Citations: 11     Fields:    Translation:AnimalsCells
    7. Weissman BP, Li NS, York D, Harris M, Piccirilli JA. Heavy atom labeled nucleotides for measurement of kinetic isotope effects. Biochim Biophys Acta. 2015 Nov; 1854(11):1737-45. PMID: 25828952; PMCID: PMC4584197.
      Citations: 7     Fields:    Translation:Cells
    8. Lu J, Koo SC, Li NS, Piccirilli JA. Synthesis of 2'-O-photocaged ribonucleoside phosphoramidites. Nucleosides Nucleotides Nucleic Acids. 2015; 34(2):114-29. PMID: 25621705; PMCID: PMC6461471.
      Citations: 6     Fields:    
    9. Huang H, Suslov NB, Li NS, Shelke SA, Evans ME, Koldobskaya Y, Rice PA, Piccirilli JA. A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat Chem Biol. 2014 Aug; 10(8):686-91. PMID: 24952597; PMCID: PMC4104137.
      Citations: 135     Fields:    Translation:AnimalsCells
    10. Tuttle N, Staley JP, Piccirilli JA, Li NS. Synthesis and incorporation of the phosphoramidite derivative of 2'-O-photocaged 3'-s-thioguanosine into oligoribonucleotides: substrate for probing the mechanism of RNA catalysis. J Org Chem. 2014 Apr 18; 79(8):3647-52. PMID: 24635216; PMCID: PMC4203407.
      Citations: 3     Fields:    Translation:Cells
    11. Fica SM, Tuttle N, Novak T, Li NS, Lu J, Koodathingal P, Dai Q, Staley JP, Piccirilli JA. RNA catalyses nuclear pre-mRNA splicing. Nature. 2013 Nov 14; 503(7475):229-34. PMID: 24196718; PMCID: PMC4666680.
      Citations: 162     Fields:    Translation:AnimalsCells
    12. Li NS, Scharf L, Adams EJ, Piccirilli JA. Highly stereocontrolled total synthesis of ß-D-mannosyl phosphomycoketide: a natural product from Mycobacterium tuberculosis. J Org Chem. 2013 Jun 21; 78(12):5970-86. PMID: 23724960.
      Citations: 6     Fields:    Translation:Cells
    13. Li NS, Frederiksen JK, Piccirilli JA. Automated solid-phase synthesis of RNA oligonucleotides containing a nonbridging phosphorodithioate linkage via phosphorothioamidites. J Org Chem. 2012 Nov 02; 77(21):9889-92. PMID: 23050987; PMCID: PMC3500914.
      Citations: 4     Fields:    Translation:Cells
    14. Li NS, Piccirilli JA. Efficient synthesis of 2'-C-a-aminomethyl-2'-deoxynucleosides. Chem Commun (Camb). 2012 Sep 11; 48(70):8754-6. PMID: 22836807.
      Citations: 1     Fields:    Translation:Cells
    15. Frederiksen JK, Li NS, Das R, Herschlag D, Piccirilli JA. Metal-ion rescue revisited: biochemical detection of site-bound metal ions important for RNA folding. RNA. 2012 Jun; 18(6):1123-41. PMID: 22539523; PMCID: PMC3358636.
      Citations: 24     Fields:    Translation:AnimalsCells
    16. Li NS, Frederiksen JK, Piccirilli JA. Synthesis, properties, and applications of oligonucleotides containing an RNA dinucleotide phosphorothiolate linkage. Acc Chem Res. 2011 Dec 20; 44(12):1257-69. PMID: 21882874; PMCID: PMC3243799.
      Citations: 16     Fields:    Translation:Cells
    17. Gilbreth RN, Truong K, Madu I, Koide A, Wojcik JB, Li NS, Piccirilli JA, Chen Y, Koide S. Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7751-6. PMID: 21518904; PMCID: PMC3093456.
      Citations: 27     Fields:    Translation:HumansCells
    18. Scharf L, Li NS, Hawk AJ, Zhang T, Fox LM, Kazen AR, Shah S, Haddadian EJ, Gumperz JE, Saghatelian A, Meredith SC, Piccirilli JA, Adams EJ, Garzón D, Faraldo-Gómez JD. The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation. Immunity. 2010 Dec 14; 33(6):853-62. PMID: 21167756; PMCID: PMC3010391.
      Citations: 64     Fields:    Translation:HumansCells
    19. Li NS, Frederiksen JK, Koo SC, Lu J, Wilson TJ, Lilley DM, Piccirilli JA. A general and efficient approach for the construction of RNA oligonucleotides containing a 5'-phosphorothiolate linkage. Nucleic Acids Res. 2011 Mar; 39(5):e31. PMID: 21148150; PMCID: PMC3061073.
      Citations: 8     Fields:    
    20. Mouw KW, Steiner AM, Ghirlando R, Li NS, Rowland SJ, Boocock MR, Stark WM, Piccirilli JA, Rice PA. Sin resolvase catalytic activity and oligomerization state are tightly coupled. J Mol Biol. 2010 Nov 19; 404(1):16-33. PMID: 20868695; PMCID: PMC2976518.
      Citations: 11     Fields:    Translation:Cells
    21. Lu J, Li NS, Koo SC, Piccirilli JA. Synthesis of pyridine, pyrimidine and pyridinone C-nucleoside phosphoramidites for probing cytosine function in RNA. J Org Chem. 2009 Nov 06; 74(21):8021-30. PMID: 19791761.
      Citations: 7     Fields:    
    22. Li NS, Lu J, Piccirilli JA. Synthesis of 2'-C-beta-methyl-2'-deoxyguanosine. J Org Chem. 2009 Mar 06; 74(5):2227-30. PMID: 19173609.
      Citations: 2     Fields:    Translation:Cells
    23. Dai Q, Saikia M, Li NS, Pan T, Piccirilli JA. Efficient chemical synthesis of AppDNA by adenylation of immobilized DNA-5'-monophosphate. Org Lett. 2009 Mar 05; 11(5):1067-70. PMID: 19191584.
      Citations: 4     Fields:    Translation:Cells
    24. Lu J, Li NS, Sengupta RN, Piccirilli JA. Synthesis and biochemical application of 2'-O-methyl-3'-thioguanosine as a probe to explore group I intron catalysis. Bioorg Med Chem. 2008 May 15; 16(10):5754-60. PMID: 18397828; PMCID: PMC2664738.
      Citations: 4     Fields:    Translation:AnimalsCells
    25. Li NS, Lu J, Piccirilli JA. Efficient synthesis of methyl 3,5-di-O-benzyl-alpha-D-ribofuranoside and application to the synthesis of 2'-C-beta-alkoxymethyluridines. Org Lett. 2007 Aug 02; 9(16):3009-12. PMID: 17629285.
      Citations: 2     Fields:    Translation:Cells
    26. Li NS, Piccirilli JA. Synthesis of 2'-C-alpha-(hydroxyalkyl) and 2'-C-alpha-alkylcytidine phosphoramidites: analogues for probing solvent interactions with RNA. J Org Chem. 2007 Feb 16; 72(4):1198-210. PMID: 17288373.
      Citations:    Fields:    Translation:Cells
    27. Ye JD, Li NS, Dai Q, Piccirilli JA. The mechanism of RNA strand scission: an experimental measure of the Brønsted coefficient, beta nuc. Angew Chem Int Ed Engl. 2007; 46(20):3714-7. PMID: 17415726.
      Citations: 12     Fields:    Translation:Cells
    28. Li NS, Piccirilli JA. Efficient synthesis of 2'-C-beta-methylguanosine. J Org Chem. 2006 May 12; 71(10):4018-20. PMID: 16674089.
      Citations: 3     Fields:    Translation:Cells
    29. Li NS, Piccirilli JA. Synthesis of the phosphoramidite derivatives of 2'-deoxy-2'-C-alpha-methylcytidine and 2'-deoxy-2'-C-alpha-hydroxymethylcytidine: analogues for chemical dissection of RNA's 2'-hydroxyl group. J Org Chem. 2004 Jul 09; 69(14):4751-9. PMID: 15230598.
      Citations: 9     Fields:    
    30. Schwans JP, Li NS, Piccirilli JA. A packing-density metric for exploring the interior of folded RNA molecules. Angew Chem Int Ed Engl. 2004 Jun 07; 43(23):3033-7. PMID: 15188472.
      Citations: 3     Fields:    Translation:Cells
    31. Gordon PM, Fong R, Deb SK, Li NS, Schwans JP, Ye JD, Piccirilli JA. New strategies for exploring RNA's 2'-OH expose the importance of solvent during group II intron catalysis. Chem Biol. 2004 Feb; 11(2):237-46. PMID: 15123285.
      Citations: 9     Fields:    Translation:HumansCells
    32. Li NS, Piccirilli JA. Synthesis of the phosphoramidite derivative of 2'-deoxy-2'-C-beta-methylcytidine. J Org Chem. 2003 Aug 22; 68(17):6799-802. PMID: 12919052.
      Citations: 3     Fields:    
    33. Li NS, Tang XQ, Piccirilli JA. 2'-C-branched ribonucleosides. 2. Synthesis of 2'-C-beta-trifluoromethyl pyrimidine ribonucleosides. Org Lett. 2001 Apr 05; 3(7):1025-8. PMID: 11277786.
      Citations:    Fields:    Translation:Cells
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