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Nan-Sheng Li

AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Shao Y, Huang H, Qin D, Li NS, Koide A, Staley JP, Koide S, Kossiakoff AA, Piccirilli JA. Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment. J Mol Biol. 2016 10 09; 428(20):4100-4114. PMID: 27593161.
      View in: PubMed
    2. Li NC, Fan J, Papadopoulos V. Sterol Carrier Protein-2, a Nonspecific Lipid-Transfer Protein, in Intracellular Cholesterol Trafficking in Testicular Leydig Cells. PLoS One. 2016; 11(2):e0149728. PMID: 26901662.
      View in: PubMed
    3. Roy S, Ly D, Castro CD, Li NS, Hawk AJ, Altman JD, Meredith SC, Piccirilli JA, Moody DB, Adams EJ. Molecular Analysis of Lipid-Reactive Vd1 ?d T Cells Identified by CD1c Tetramers. J Immunol. 2016 Feb 15; 196(4):1933-42. PMID: 26755823.
      View in: PubMed
    4. Lu YC, Nazarko OV, Sando R, Salzman GS, Li NS, Südhof TC, Araç D. Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. Structure. 2015 Sep 01; 23(9):1678-1691. PMID: 26235030.
      View in: PubMed
    5. DasGupta S, Shelke SA, Li NS, Piccirilli JA. Spinach RNA aptamer detects lead(II) with high selectivity. Chem Commun (Camb). 2015 May 28; 51(43):9034-7. PMID: 25940073.
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    6. Weissman BP, Li NS, York D, Harris M, Piccirilli JA. Heavy atom labeled nucleotides for measurement of kinetic isotope effects. Biochim Biophys Acta. 2015 Nov; 1854(11):1737-45. PMID: 25828952.
      View in: PubMed
    7. Lu J, Koo SC, Li NS, Piccirilli JA. Synthesis of 2'-O-photocaged ribonucleoside phosphoramidites. Nucleosides Nucleotides Nucleic Acids. 2015; 34(2):114-29. PMID: 25621705.
      View in: PubMed
    8. Huang H, Suslov NB, Li NS, Shelke SA, Evans ME, Koldobskaya Y, Rice PA, Piccirilli JA. A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat Chem Biol. 2014 Aug; 10(8):686-91. PMID: 24952597.
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    9. Li NS, Tuttle N, Staley JP, Piccirilli JA. Synthesis and incorporation of the phosphoramidite derivative of 2'-O-photocaged 3'-s-thioguanosine into oligoribonucleotides: substrate for probing the mechanism of RNA catalysis. J Org Chem. 2014 Apr 18; 79(8):3647-52. PMID: 24635216.
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    10. Fica SM, Tuttle N, Novak T, Li NS, Lu J, Koodathingal P, Dai Q, Staley JP, Piccirilli JA. RNA catalyses nuclear pre-mRNA splicing. Nature. 2013 Nov 14; 503(7475):229-34. PMID: 24196718.
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    11. Li NS, Scharf L, Adams EJ, Piccirilli JA. Highly stereocontrolled total synthesis of ß-D-mannosyl phosphomycoketide: a natural product from Mycobacterium tuberculosis. J Org Chem. 2013 Jun 21; 78(12):5970-86. PMID: 23724960.
      View in: PubMed
    12. Li NS, Frederiksen JK, Piccirilli JA. Automated solid-phase synthesis of RNA oligonucleotides containing a nonbridging phosphorodithioate linkage via phosphorothioamidites. J Org Chem. 2012 Nov 02; 77(21):9889-92. PMID: 23050987.
      View in: PubMed
    13. Li NS, Piccirilli JA. Efficient synthesis of 2'-C-a-aminomethyl-2'-deoxynucleosides. Chem Commun (Camb). 2012 Sep 11; 48(70):8754-6. PMID: 22836807.
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    14. Frederiksen JK, Li NS, Das R, Herschlag D, Piccirilli JA. Metal-ion rescue revisited: biochemical detection of site-bound metal ions important for RNA folding. RNA. 2012 Jun; 18(6):1123-41. PMID: 22539523.
      View in: PubMed
    15. Li NS, Frederiksen JK, Piccirilli JA. Synthesis, properties, and applications of oligonucleotides containing an RNA dinucleotide phosphorothiolate linkage. Acc Chem Res. 2011 Dec 20; 44(12):1257-69. PMID: 21882874.
      View in: PubMed
    16. Gilbreth RN, Truong K, Madu I, Koide A, Wojcik JB, Li NS, Piccirilli JA, Chen Y, Koide S. Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7751-6. PMID: 21518904.
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    17. Scharf L, Li NS, Hawk AJ, Garzón D, Zhang T, Fox LM, Kazen AR, Shah S, Haddadian EJ, Gumperz JE, Saghatelian A, Faraldo-Gómez JD, Meredith SC, Piccirilli JA, Adams EJ. The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation. Immunity. 2010 Dec 14; 33(6):853-62. PMID: 21167756.
      View in: PubMed
    18. Li NS, Frederiksen JK, Koo SC, Lu J, Wilson TJ, Lilley DM, Piccirilli JA. A general and efficient approach for the construction of RNA oligonucleotides containing a 5'-phosphorothiolate linkage. Nucleic Acids Res. 2011 Mar; 39(5):e31. PMID: 21148150.
      View in: PubMed
    19. Mouw KW, Steiner AM, Ghirlando R, Li NS, Rowland SJ, Boocock MR, Stark WM, Piccirilli JA, Rice PA. Sin resolvase catalytic activity and oligomerization state are tightly coupled. J Mol Biol. 2010 Nov 19; 404(1):16-33. PMID: 20868695.
      View in: PubMed
    20. Lu J, Li NS, Koo SC, Piccirilli JA. Synthesis of pyridine, pyrimidine and pyridinone C-nucleoside phosphoramidites for probing cytosine function in RNA. J Org Chem. 2009 Nov 06; 74(21):8021-30. PMID: 19791761.
      View in: PubMed
    21. Li NS, Lu J, Piccirilli JA. Synthesis of 2'-C-beta-methyl-2'-deoxyguanosine. J Org Chem. 2009 Mar 06; 74(5):2227-30. PMID: 19173609.
      View in: PubMed
    22. Dai Q, Saikia M, Li NS, Pan T, Piccirilli JA. Efficient chemical synthesis of AppDNA by adenylation of immobilized DNA-5'-monophosphate. Org Lett. 2009 Mar 05; 11(5):1067-70. PMID: 19191584.
      View in: PubMed
    23. Lu J, Li NS, Sengupta RN, Piccirilli JA. Synthesis and biochemical application of 2'-O-methyl-3'-thioguanosine as a probe to explore group I intron catalysis. Bioorg Med Chem. 2008 May 15; 16(10):5754-60. PMID: 18397828.
      View in: PubMed
    24. Li NS, Lu J, Piccirilli JA. Efficient synthesis of methyl 3,5-di-O-benzyl-alpha-D-ribofuranoside and application to the synthesis of 2'-C-beta-alkoxymethyluridines. Org Lett. 2007 Aug 02; 9(16):3009-12. PMID: 17629285.
      View in: PubMed
    25. Li NS, Piccirilli JA. Synthesis of 2'-C-alpha-(hydroxyalkyl) and 2'-C-alpha-alkylcytidine phosphoramidites: analogues for probing solvent interactions with RNA. J Org Chem. 2007 Feb 16; 72(4):1198-210. PMID: 17288373.
      View in: PubMed
    26. Ye JD, Li NS, Dai Q, Piccirilli JA. The mechanism of RNA strand scission: an experimental measure of the Brønsted coefficient, beta nuc. Angew Chem Int Ed Engl. 2007; 46(20):3714-7. PMID: 17415726.
      View in: PubMed
    27. Li NS, Piccirilli JA. Efficient synthesis of 2'-C-beta-methylguanosine. J Org Chem. 2006 May 12; 71(10):4018-20. PMID: 16674089.
      View in: PubMed
    28. Li NS, Piccirilli JA. Synthesis of the phosphoramidite derivatives of 2'-deoxy-2'-C-alpha-methylcytidine and 2'-deoxy-2'-C-alpha-hydroxymethylcytidine: analogues for chemical dissection of RNA's 2'-hydroxyl group. J Org Chem. 2004 Jul 09; 69(14):4751-9. PMID: 15230598.
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    29. Schwans JP, Li NS, Piccirilli JA. A packing-density metric for exploring the interior of folded RNA molecules. Angew Chem Int Ed Engl. 2004 Jun 07; 43(23):3033-7. PMID: 15188472.
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    30. Gordon PM, Fong R, Deb SK, Li NS, Schwans JP, Ye JD, Piccirilli JA. New strategies for exploring RNA's 2'-OH expose the importance of solvent during group II intron catalysis. Chem Biol. 2004 Feb; 11(2):237-46. PMID: 15123285.
      View in: PubMed
    31. Li NS, Piccirilli JA. Synthesis of the phosphoramidite derivative of 2'-deoxy-2'-C-beta-methylcytidine. J Org Chem. 2003 Aug 22; 68(17):6799-802. PMID: 12919052.
      View in: PubMed
    32. Li NS, Tang XQ, Piccirilli JA. 2'-C-branched ribonucleosides. 2. Synthesis of 2'-C-beta-trifluoromethyl pyrimidine ribonucleosides. Org Lett. 2001 Apr 05; 3(7):1025-8. PMID: 11277786.
      View in: PubMed
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