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Yu-Ying He

InstitutionUniversity of Chicago
AddressChicago IL 60637
Phone+1 (773) 795-4696
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    Our research addresses the fundamental questions: how normal cells respond to environmental carcinogens and evolve into cancerous cells. In particular, our group focuses on the role of epitranscriptomics, epigenetics, and autophagy in regulating genomic integrity and cellular homeostasis and to investigate their impact on cancer development and therapeutic resistance, with an emphasis on skin cancer including squamous cancer and melanoma. Our long-term goal is to identify previously unrecognized, therapeutically accessible molecular regulatory networks that predict susceptibility to skin cancer, and improve our ability to prevent and treat these cancers.
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    Chinese Academy of Sciences, ChinaPhD07/2000Organic Chemistry

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tan Y, Mosallanejad K, Zhang Q, O'Brien S, Clements M, Perper S, Wilson S, Chaulagain S, Wang J, Abdalla M, Al-Saidi H, Butt D, Clabbers A, Ofori K, Dillon B, Harvey B, Memmott J, Negron C, Winarta D, Tan C, Biswas A, Dong F, Morales-Tirado V, Lu X, Singh G, White M, Ashley S, Knight H, Westmoreland S, Phillips L, Carr T, Reinke-Breen L, Singh R, Xu J, Wu K, Rinaldi L, Stoll B, He YD, Hazelwood L, Karman J, McCluskey A, Stine W, Correia I, Gauld S, Levesque MC, Veldman G, Hubeau C, Radstake T, Sadhukhan R, Fiebiger E. IL11-mediated stromal cell activation may not be the master regulator of pro-fibrotic signaling downstream of TGFß. Front Immunol. 2024; 15:1293883. PMID: 38455057; PMCID: PMC10917968.
      Citations:    Fields:    Translation:HumansCells
    2. He S, Wang Q, Chen L, He YJ, Wang X, Qu S. miR-100a-5p-enriched exosomes derived from mesenchymal stem cells enhance the anti-oxidant effect in a Parkinson's disease model via regulation of Nox4/ROS/Nrf2 signaling. J Transl Med. 2023 10 24; 21(1):747. PMID: 37875930; PMCID: PMC10594913.
      Citations: 1     Fields:    Translation:AnimalsCells
    3. Cui YH, Yang S, Wei J, Shea CR, Zhong W, Wang F, Shah P, Kibriya MG, Cui X, Ahsan H, He C, He YY. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183. PMID: 33846348; PMCID: PMC8041927.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    4. Qiang L, Yang S, Cui YH, He YY. Keratinocyte autophagy enables the activation of keratinocytes and fibroblastsand facilitates wound healing. Autophagy. 2021 09; 17(9):2128-2143. PMID: 32866426; PMCID: PMC8496719.
      Citations: 57     Fields:    Translation:AnimalsCells
    5. Yang S, Wei J, Cui YH, Park G, Shah P, Deng Y, Aplin AE, Lu Z, Hwang S, He C, He YY. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 06 25; 10(1):2782. PMID: 31239444; PMCID: PMC6592937.
      Citations: 325     Fields:    Translation:HumansAnimalsCells
    6. Shah P, Zhao B, Qiang L, He YY. Phosphorylation of xeroderma pigmentosum group C regulates ultraviolet-induced DNA damage repair. Nucleic Acids Res. 2018 06 01; 46(10):5050-5060. PMID: 29660033; PMCID: PMC6007576.
      Citations: 11     Fields:    Translation:HumansCells
    7. Robinson M, Shah P, Cui YH, He YY. The Role of Dynamic m6 A RNA Methylation in Photobiology. Photochem Photobiol. 2019 01; 95(1):95-104. PMID: 29729018; PMCID: PMC6309319.
      Citations: 18     Fields:    Translation:HumansCells
    8. Xu Y, Yang X, Wang T, Yang L, He YY, Miskimins K, Qian SY. Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-?-linolenic acid peroxidation dependent mechanism. BMC Cancer. 2018 03 27; 18(1):330. PMID: 29587668; PMCID: PMC5870477.
      Citations: 16     Fields:    Translation:HumansCells
    9. Shah P, Qiang L, Yang S, Soltani K, He YY. Regulation of XPC deubiquitination by USP11 in repair of UV-induced DNA damage. Oncotarget. 2017 Nov 14; 8(57):96522-96535. PMID: 29228550; PMCID: PMC5722502.
      Citations: 16     Fields:    
    10. Qiang L, Sample A, Liu H, Wu X, He YY. Epidermal SIRT1 regulates inflammation, cell migration, and wound healing. Sci Rep. 2017 10 26; 7(1):14110. PMID: 29074993; PMCID: PMC5658409.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    11. Sample A, Zhao B, Wu C, Qian S, Shi X, Aplin A, He YY. The Autophagy Receptor Adaptor p62 is Up-regulated by UVA Radiation in Melanocytes and in Melanoma Cells. Photochem Photobiol. 2018 05; 94(3):432-437. PMID: 28715145; PMCID: PMC5771989.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    12. Nakai K, He YY, Nishiyama F, Naruse F, Haba R, Kushida Y, Katsuki N, Moriue T, Yoneda K, Kubota Y. IL-17A induces heterogeneous macrophages, and it does not alter the effects of lipopolysaccharides on macrophage activation in the skin of mice. Sci Rep. 2017 09 29; 7(1):12473. PMID: 28963556; PMCID: PMC5622065.
      Citations: 23     Fields:    Translation:AnimalsCells
    13. Sample A, He YY. Mechanisms and prevention of UV-induced melanoma. Photodermatol Photoimmunol Photomed. 2018 Jan; 34(1):13-24. PMID: 28703311; PMCID: PMC5760354.
      Citations: 101     Fields:    Translation:HumansCells
    14. Sample A, Zhao B, Qiang L, He YY. Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation. J Biol Chem. 2017 09 08; 292(36):14786-14795. PMID: 28724634; PMCID: PMC5592660.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    15. Sample A, He YY. Autophagy in UV Damage Response. Photochem Photobiol. 2017 07; 93(4):943-955. PMID: 27935061; PMCID: PMC5466513.
      Citations: 27     Fields:    Translation:Humans
    16. Shah P, Trinh E, Qiang L, Xie L, Hu WY, Prins GS, Pi J, He YY. Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer. Molecules. 2017 Jan 24; 22(2). PMID: 28125038; PMCID: PMC5361890.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    17. Yang S, Qiang L, Sample A, Shah P, He YY. NF-?B Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell Resistance. J Biol Chem. 2017 02 24; 292(8):3379-3388. PMID: 28082672; PMCID: PMC5336170.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    18. Qiang L, Sample A, Shea CR, Soltani K, Macleod KF, He YY. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis. Autophagy. 2017; 13(12):2086-2103. PMID: 28933598; PMCID: PMC5788558.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    19. Zhao B, Shah P, Qiang L, He TC, Budanov A, He YY. Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes. Photochem Photobiol. 2017 01; 93(1):375-381. PMID: 27463837; PMCID: PMC5272907.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    20. Zhao B, Qiang L, Joseph J, Kalyanaraman B, He YY, Viollet B. Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival. Genes Dis. 2016 Mar; 3(1):82-87. PMID: 28066797; PMCID: PMC5215801.
      Citations: 26     
    21. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Akematsu T, Akporiaye ET, Al-Rubeai M, Albanese C, Albani D, Albert ML, Aldudo J, Alirezaei M, Alloza I, Almasan A, Alnemri ES, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bao H, Barrachina MD, Barreiro E, Bartel B, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beck GR, Beckham JD, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernassola F, Bertolotti A, Bess AS, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bingol B, Bird SW, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Bonaldo P, Bordi M, Boulton ME, Bouret SG, Bozhkov PV, Brady N, Braga VM, Brancolini C, Brennan LA, Bresnick EH, Brest P, Bridges D, Brini M, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burke RE, Burmeister M, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Campanella M, Campbell GR, Campbell M, Campello S, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carroll B, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Cervia D, Cetrullo S, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Clague MJ, Clarke PG, Clarke R, Clementi E, Cnop M, Cocco T, Cohen EE, Colecchia D, Coletto L, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, Dahmen U, Dai C, Dai W, Dai Y, Dalby KN, Dalla Valle L, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652; PMCID: PMC4835977.
      Citations: 2775     Fields:    Translation:HumansAnimals
    22. Qiang L, Zhao B, Shah P, Sample A, Yang S, He YY. Autophagy positively regulates DNA damage recognition by nucleotide excision repair. Autophagy. 2016; 12(2):357-68. PMID: 26565512; PMCID: PMC4835978.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    23. Liu H, Yue J, Gou X, Chen SY, Wu X, Lei Q, He YY. Ultraviolet B Inhibits Skin Wound Healing by Affecting Focal Adhesion Dynamics. Photochem Photobiol. 2015 Jul-Aug; 91(4):909-16. PMID: 25918970; PMCID: PMC4513668.
      Citations: 5     Fields:    Translation:AnimalsCells
    24. Chastkofsky MI, Bie W, Ball-Kell SM, He YY, Tyner AL. Protein Tyrosine Kinase 6 Regulates UVB-Induced Signaling and Tumorigenesis in Mouse Skin. J Invest Dermatol. 2015 Oct; 135(10):2492-2501. PMID: 25938342; PMCID: PMC4567952.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    25. Shah P, He YY. Molecular regulation of UV-induced DNA repair. Photochem Photobiol. 2015 Mar-Apr; 91(2):254-64. PMID: 25534312; PMCID: PMC4355264.
      Citations: 31     Fields:    Translation:HumansCells
    26. Kim Y, He YY. Ultraviolet radiation-induced non-melanoma skin cancer: Regulation of DNA damage repair and inflammation. Genes Dis. 2014 Dec 01; 1(2):188-198. PMID: 25642450; PMCID: PMC4307792.
      Citations: 76     
    27. Ming M, Zhao B, Shea CR, Shah P, Qiang L, White SR, Sims DM, He YY. Loss of sirtuin 1 (SIRT1) disrupts skin barrier integrity and sensitizes mice to epicutaneous allergen challenge. J Allergy Clin Immunol. 2015 Apr; 135(4):936-945.e4. PMID: 25445829; PMCID: PMC4388755.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    28. Zhao B, Shah P, Budanov AV, Qiang L, Ming M, Aplin A, Sims DM, He YY. Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells. J Biol Chem. 2014 Dec 26; 289(52):35806-14. PMID: 25378405; PMCID: PMC4276849.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    29. Ming M, Han W, Zhao B, Sundaresan NR, Deng CX, Gupta MP, He YY. SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer. Cancer Res. 2014 Oct 15; 74(20):5925-33. PMID: 25320180; PMCID: PMC4203414.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    30. Qiang L, He YY. Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition. Autophagy. 2014 Oct 01; 10(10):1864-5. PMID: 25126736; PMCID: PMC4198370.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    31. Ming M, Zhao B, Qiang L, He YY. Effect of immunosuppressants tacrolimus and mycophenolate mofetil on the keratinocyte UVB response. Photochem Photobiol. 2015 Jan-Feb; 91(1):242-7. PMID: 25039758; PMCID: PMC4294972.
      Citations: 11     Fields:    Translation:HumansCells
    32. Qiang L, Zhao B, Ming M, Wang N, He TC, Hwang S, Thorburn A, He YY. Regulation of cell proliferation and migration by p62 through stabilization of Twist1. Proc Natl Acad Sci U S A. 2014 Jun 24; 111(25):9241-6. PMID: 24927592; PMCID: PMC4078859.
      Citations: 132     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    33. Ming M, Qiang L, Zhao B, He YY. Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin. Exp Dermatol. 2014 Mar; 23(3):207-9. PMID: 24438005; PMCID: PMC3957270.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    34. Kim I, He YY. Targeting the AMP-Activated Protein Kinase for Cancer Prevention and Therapy. Front Oncol. 2013; 3:175. PMID: 23875169; PMCID: PMC3711071.
      Citations: 64     
    35. Qiang L, Wu C, Ming M, Viollet B, He YY. Autophagy controls p38 activation to promote cell survival under genotoxic stress. J Biol Chem. 2013 Jan 18; 288(3):1603-11. PMID: 23212914; PMCID: PMC3548470.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    36. Zhao B, Ming M, He YY. Suppression of PTEN transcription by UVA. J Biochem Mol Toxicol. 2013 Feb; 27(2):184-91. PMID: 23129115; PMCID: PMC3567256.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    37. Han W, Soltani K, Ming M, He YY. Deregulation of XPC and CypA by cyclosporin A: an immunosuppression-independent mechanism of skin carcinogenesis. Cancer Prev Res (Phila). 2012 Sep; 5(9):1155-62. PMID: 22846842; PMCID: PMC3435459.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    38. Han W, Ming M, Zhao R, Pi J, Wu C, He YY. Nrf1 CNC-bZIP protein promotes cell survival and nucleotide excision repair through maintaining glutathione homeostasis. J Biol Chem. 2012 May 25; 287(22):18788-95. PMID: 22500024; PMCID: PMC3365774.
      Citations: 26     Fields:    Translation:HumansCells
    39. Ming M, He YY. PTEN in DNA damage repair. Cancer Lett. 2012 Jun 28; 319(2):125-129. PMID: 22266095; PMCID: PMC3326178.
      Citations: 68     Fields:    Translation:AnimalsCells
    40. Ming M, Feng L, Shea CR, Soltani K, Zhao B, Han W, Smart RC, Trempus CS, He YY. PTEN positively regulates UVB-induced DNA damage repair. Cancer Res. 2011 Aug 01; 71(15):5287-95. PMID: 21771908; PMCID: PMC3148338.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    41. Han W, Ming M, He YY. Caffeine promotes ultraviolet B-induced apoptosis in human keratinocytes without complete DNA repair. J Biol Chem. 2011 Jul 01; 286(26):22825-32. PMID: 21561856; PMCID: PMC3123050.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    42. Ming M, Shea CR, Feng L, Soltani K, He YY. UVA induces lesions resembling seborrheic keratoses in mice with keratinocyte-specific PTEN downregulation. J Invest Dermatol. 2011 Jul; 131(7):1583-6. PMID: 21390050; PMCID: PMC3116047.
      Citations: 7     Fields:    Translation:AnimalsCells
    43. Thompson EA, Zhu S, Hall JR, House JS, Ranjan R, Burr JA, He YY, Owens DM, Smart RC. C/EBPa expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBPa confers susceptibility to UVB-induced skin squamous cell carcinomas. J Invest Dermatol. 2011 Jun; 131(6):1339-46. PMID: 21346772; PMCID: PMC3418815.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    44. Ming M, Shea CR, Guo X, Li X, Soltani K, Han W, He YY. Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22623-8. PMID: 21149730; PMCID: PMC3012476.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    45. Zhao B, He YY. Recent advances in the prevention and treatment of skin cancer using photodynamic therapy. Expert Rev Anticancer Ther. 2010 Nov; 10(11):1797-809. PMID: 21080805; PMCID: PMC3030451.
      Citations: 45     Fields:    Translation:Humans
    46. Lei X, Liu B, Han W, Ming M, He YY. UVB-Induced p21 degradation promotes apoptosis of human keratinocytes. Photochem Photobiol Sci. 2010 Dec; 9(12):1640-8. PMID: 20931139; PMCID: PMC3035101.
      Citations: 18     Fields:    Translation:HumansCells
    47. Koker EB, Bilski PJ, Motten AG, Zhao B, Chignell CF, He YY. Real-time visualization of photochemically induced fluorescence of 8-halogenated quinolones: lomefloxacin, clinafloxacin and Bay3118 in live human HaCaT keratinocytes. Photochem Photobiol. 2010 Jul-Aug; 86(4):792-7. PMID: 20492567; PMCID: PMC2980828.
      Citations: 1     Fields:    Translation:HumansCells
    48. Han W, Ming M, He TC, He YY. Immunosuppressive cyclosporin A activates AKT in keratinocytes through PTEN suppression: implications in skin carcinogenesis. J Biol Chem. 2010 Apr 09; 285(15):11369-77. PMID: 20154081; PMCID: PMC2857015.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    49. Zhao B, Yin JJ, Bilski PJ, Chignell CF, Roberts JE, He YY. Enhanced photodynamic efficacy towards melanoma cells by encapsulation of Pc4 in silica nanoparticles. Toxicol Appl Pharmacol. 2009 Dec 01; 241(2):163-72. PMID: 19695274; PMCID: PMC2783992.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    50. Ming M, He YY. PTEN: new insights into its regulation and function in skin cancer. J Invest Dermatol. 2009 Sep; 129(9):2109-12. PMID: 19340009; PMCID: PMC2758921.
      Citations: 28     Fields:    Translation:HumansAnimals
    51. Zhao B, He YY, Chignell CF, Yin JJ, Andley U, Roberts JE. Difference in phototoxicity of cyclodextrin complexed fullerene [(gamma-CyD)2/C60] and its aggregated derivatives toward human lens epithelial cells. Chem Res Toxicol. 2009 Apr; 22(4):660-7. PMID: 19281132; PMCID: PMC2800100.
      Citations: 7     Fields:    Translation:HumansCells
    52. Han W, He YY. Requirement for metalloproteinase-dependent ERK and AKT activation in UVB-induced G1-S cell cycle progression of human keratinocytes. Photochem Photobiol. 2009 Jul-Aug; 85(4):997-1003. PMID: 19222789; PMCID: PMC2720095.
      Citations: 16     Fields:    Translation:HumansCells
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