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Yusuke Nakamura
Title
Emeritus/Emerita, Professor
Institution
University of Chicago
Department
Medicine
Address
Chicago IL 60637
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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
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to make corrections and additions.
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PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Hasei J, Nakahara R, Otsuka Y,
Nakamura Y
, Hironari T, Kahara N, Miwa S, Ohshika S, Nishimura S, Ikuta K, Osaki S, Yoshida A, Fujiwara T, Nakata E, Kunisada T, Ozaki T. High-quality expert annotations enhance artificial intelligence model accuracy for osteosarcoma X-ray diagnosis. Cancer Sci. 2024 Sep 02.
PMID:
39223070
.
Citations:
Okamura K, Wang L, Nagayama S, Yamashita M, Tate T, Matsumoto S, Takamatsu M, Kitano S, Kiyotani K,
Nakamura Y
. Characterization of double-negative T cells in colorectal cancers and their corresponding lymph nodes. Oncoimmunology. 2024; 13(1):2373530.
PMID:
38979545
; PMCID:
PMC11229752
.
Citations:
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Translation:
Humans
Cells
Chiablaem K, Jinawath A, Nuanpirom J, Arora JK, Nasaree S, Thanomchard T, Singhto N, Chittavanich P, Suktitipat B, Charoensawan V, Chairoungdua A, Jinn-Chyuan Sheu J, Kiyotani K, Svasti J,
Nakamura Y
, Jinawath N. Identification of RNF213 as a Potential Suppressor of Local Invasion in Intrahepatic Cholangiocarcinoma. Lab Invest. 2024 Jul; 104(7):102074.
PMID:
38723854
.
Citations:
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Humans
Cells
Nakamura Y
, Wolf SP, Anastasopoulou V, Drousch K, Diehl MI, Engels B, Yew PY, Kiyotani K, Schreiber K,
Schreiber H
, Leisegang M. One CD4+TCR and One CD8+TCR Targeting Autochthonous Neoantigens Are Essential and Sufficient for Tumor Eradication. Clin Cancer Res. 2024 Apr 15; 30(8):1642-1654.
PMID:
38190111
; PMCID:
PMC11018470
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Patel JN, Jiang C, Owzar K, Hertz DL, Wang J, Mulkey FA, Kelly WK, Halabi S, Furukawa Y, Lassiter C, Dorsey SG, Friedman PN, Small EJ, Carducci MA, Kelley MJ,
Nakamura Y
, Kubo M,
Ratain MJ
, Morris MJ, McLeod HL. Pharmacogenetic and clinical risk factors for bevacizumab-related gastrointestinal hemorrhage in prostate cancer patients treated on CALGB 90401 (Alliance). Pharmacogenomics J. 2024 Mar 04; 24(2):6.
PMID:
38438359
; PMCID:
PMC10912014
.
Citations:
Fields:
Mol
Molecular Biology
Pha
Pharmacology
Translation:
Humans
Morisaki S, Onishi H, Morisaki T, Kubo M, Umebayashi M, Tanaka H, Koya N, Nakagawa S, Tsujimura K, Yoshimura S, Yew PY, Kiyotani K,
Nakamura Y
, Nakamura M, Kitazono T, Morisaki T. Immunological analysis of hybrid neoantigen peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine. Front Immunol. 2023; 14:1223331.
PMID:
37881436
; PMCID:
PMC10595142
.
Citations:
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Sudo H, Tsuji AB, Sugyo A, Harada Y, Nagayama S, Katagiri T,
Nakamura Y
, Higashi T. Head-to-head comparison of three chelates reveals DOTAGA promising for 225 Ac labeling of anti-FZD10 antibody OTSA101. Cancer Sci. 2023 Dec; 114(12):4677-4690.
PMID:
37781962
; PMCID:
PMC10728013
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Animals
Nigam N, Bernard B, Sevilla S, Kim S, Dar MS, Tsai D, Robbins Y, Burkitt K, Sievers C, Allen CT, Bennett RL, Tettey TT, Carter B, Rinaldi L,
Lingen MW
, Sater H, Edmondson EF, Moshiri A, Saeed A, Cheng H, Luo X, Brennan K, Koparde V, Chen C, Das S, Andresson T, Abdelmaksoud A, Murali M, Sakata S, Takeuchi K, Chari R,
Nakamura Y
, Uppaluri R, Sunwoo JB, Van Waes C, Licht JD, Hager GL, Saloura V. SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck. Cell Rep. 2023 07 25; 42(7):112823.
PMID:
37463106
; PMCID:
PMC10407766
.
Citations:
4
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Yamamoto H, Yamada T, Miyazaki K, Yamashita T, Kato T, Ohara K,
Nakamura Y
, Akizawa T. Treatment satisfaction with molidustat in CKD-related anemia in non-dialysis patients: a post-hoc analysis of two clinical trials. Clin Exp Nephrol. 2023 Aug; 27(8):651-659.
PMID:
37095342
; PMCID:
PMC10352152
.
Citations:
Fields:
Nep
Nephrology
Translation:
Humans
CT
Clinical Trials
Tate T, Matsumoto S, Nemoto K, Nagayama S, Obama K,
Nakamura Y
, Kiyotani K, Leisegang M. Identification of T Cell Receptors Targeting a Neoantigen Derived from Recurrently Mutated FGFR3. Cancers (Basel). 2023 Feb 06; 15(4).
PMID:
36831375
; PMCID:
PMC9953830
.
Citations:
1
Chan HT, Nagayama S, Otaki M, Chin YM, Fukunaga Y, Ueno M,
Nakamura Y
, Low SK. Tumor-informed or tumor-agnostic circulating tumor DNA as a biomarker for risk of recurrence in resected colorectal cancer patients. Front Oncol. 2022; 12:1055968.
PMID:
36776372
; PMCID:
PMC9909342
.
Citations:
11
Watanabe K, Nakamura T, Kimura Y, Motoya M, Kojima S, Kuraya T, Murakami T, Kaneko T, Shinohara Y, Kitayama Y, Fukuda K, Hatanaka KC, Mitsuhashi T, Pittella-Silva F, Yamaguchi T, Hirano S,
Nakamura Y
, Low SK. Tumor-Informed Approach Improved ctDNA Detection Rate in Resected Pancreatic Cancer. Int J Mol Sci. 2022 Sep 29; 23(19).
PMID:
36232820
; PMCID:
PMC9570468
.
Citations:
5
Fields:
Bio
Biochemistry
Che
Chemistry
Mol
Molecular Biology
Translation:
Humans
Wang Q, Wang Y, Wang X,
Nakamura Y
, Hydbring P, Yamauchi Y, Zhao X, Cao M. Development and validation of a dynamic survival nomogram for metastatic non-small cell lung cancer based on the SEER database and an external validation cohort. Transl Lung Cancer Res. 2022 Aug; 11(8):1678-1691.
PMID:
36090634
; PMCID:
PMC9459611
.
Citations:
7
Hikichi T, Sakamoto M, Harada M, Saito M, Yamane Y, Tokumura K,
Nakamura Y
. Correction: Identification of cytotoxic T cells and their T cell receptor sequences targeting COVID-19 using MHC class I-binding peptides. J Hum Genet. 2022 Jul; 67(7):445-446.
PMID:
35194135
; PMCID:
PMC8862411
.
Citations:
Fields:
Gen
Genetics
Okamura K, Nagayama S, Tate T, Chan HT, Kiyotani K,
Nakamura Y
. Lymphocytes in tumor-draining lymph nodes co-cultured with autologous tumor cells for adoptive cell therapy. J Transl Med. 2022 05 23; 20(1):241.
PMID:
35606862
; PMCID:
PMC9125345
.
Citations:
5
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Low SK, Ariyasu R, Uchibori K, Hayashi R, Chan HT, Chin YM, Akita T, Harutani Y, Kiritani A, Tsugitomi R, Manabe R, Ogusu S, Amino Y, Kitazono S, Yanagitani N,
Nakamura Y
, Nishio M. Rapid genomic profiling of circulating tumor DNA in non-small cell lung cancer using Oncomine Precision Assay with Genexus™ integrated sequencer. Transl Lung Cancer Res. 2022 May; 11(5):711-721.
PMID:
35693289
; PMCID:
PMC9186171
.
Citations:
8
Thomeas-McEwing V, Psotka MA, Gamazon ER, Friedman P, Konkashbaev A, Kubo M,
Nakamura Y
,
Ratain MJ
, Benza RL,
Cox NJ
, Gomberg-Maitland MI, Maitland ML. Two polymorphic gene loci associated with treprostinil dose in pulmonary arterial hypertension. Pharmacogenet Genomics. 2022 06 01; 32(4):144-151.
PMID:
35383711
.
Citations:
1
Fields:
Gen
Genetics
Pha
Pharmacology
Translation:
Humans
Chin YM, Shibayama T, Chan HT, Otaki M, Hara F, Kobayashi T, Kobayashi K, Hosonaga M, Fukada I, Inagaki L, Ono M, Ito Y, Takahashi S, Ohno S, Ueno T,
Nakamura Y
, Low SK. Serial circulating tumor DNA monitoring of CDK4/6 inhibitors response in metastatic breast cancer. Cancer Sci. 2022 May; 113(5):1808-1820.
PMID:
35201661
; PMCID:
PMC9128178
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Hikichi T, Sakamoto M, Harada M, Saito M, Yamane Y, Tokumura K,
Nakamura Y
. Identification of cytotoxic T cells and their T cell receptor sequences targeting COVID-19 using MHC class I-binding peptides. J Hum Genet. 2022 Jul; 67(7):411-419.
PMID:
35110673
; PMCID:
PMC8807680
.
Citations:
3
Fields:
Gen
Genetics
Translation:
Humans
Cells
Yasuda T, Nishiki K, Hiraki Y, Kato H, Iwama M, Shiraishi O, Yasuda A, Shinkai M, Kimura Y, Sukegawa Y, Chiba Y, Imano M, Takeda K, Satou T, Shiozaki H,
Nakamura Y
. Phase II Adjuvant Cancer-specific Vaccine Therapy for Esophageal Cancer Patients Curatively Resected After Preoperative Therapy With Pathologically Positive Nodes; Possible Significance of Tumor Immune Microenvironment in its Clinical Effects. Ann Surg. 2022 01 01; 275(1):e155-e162.
PMID:
33055588
.
Citations:
10
Fields:
Gen
General Surgery
Translation:
Humans
CT
Clinical Trials
Sudo H, Tsuji AB, Sugyo A, Harada Y, Nagayama S, Katagiri T,
Nakamura Y
, Higashi T. FZD10-targeted a-radioimmunotherapy with 225 Ac-labeled OTSA101 achieves complete remission in a synovial sarcoma model. Cancer Sci. 2022 Feb; 113(2):721-732.
PMID:
34935247
; PMCID:
PMC8819345
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Sakaue S, Kanai M, Tanigawa Y, Karjalainen J, Kurki M, Koshiba S, Narita A, Konuma T, Yamamoto K, Akiyama M, Ishigaki K, Suzuki A, Suzuki K, Obara W, Yamaji K, Takahashi K, Asai S, Takahashi Y, Suzuki T, Shinozaki N, Yamaguchi H, Minami S, Murayama S, Yoshimori K, Nagayama S, Obata D, Higashiyama M, Masumoto A, Koretsune Y, FinnGen, Ito K, Terao C, Yamauchi T, Komuro I, Kadowaki T, Tamiya G, Yamamoto M,
Nakamura Y
, Kubo M, Murakami Y, Yamamoto K, Kamatani Y, Palotie A, Rivas MA, Daly MJ, Matsuda K, Okada Y. A cross-population atlas of genetic associations for 220 human phenotypes. Nat Genet. 2021 10; 53(10):1415-1424.
PMID:
34594039
.
Citations:
450
Fields:
Gen
Genetics
Translation:
Humans
Nagayama S, Low SK, Kiyotani K,
Nakamura Y
. Precision Medicine for Colorectal Cancer with Liquid Biopsy and Immunotherapy. Cancers (Basel). 2021 Sep 25; 13(19).
PMID:
34638288
; PMCID:
PMC8507967
.
Citations:
5
Ichimiya S, Fujimura A, Masuda M, Masuda S, Yasumatsu R, Umebayashi M, Tanaka H, Koya N, Nakagawa S, Yew PY, Yoshimura S, Onishi H, Nakamura M,
Nakamura Y
, Morisaki T. Contribution of pre-existing neoantigen-specific T cells to a durable complete response after tumor-pulsed dendritic cell vaccine plus nivolumab therapy in a patient with metastatic salivary duct carcinoma. Immunol Invest. 2022 Jul; 51(5):1498-1514.
PMID:
34486463
.
Citations:
5
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Inazawa J, Miki Y,
Nakamura Y
. Integrative cancer genomics in the era of precision cancer medicine. J Hum Genet. 2021 09; 66(9):843.
PMID:
34429508
.
Citations:
Fields:
Gen
Genetics
Translation:
Humans
Kiyotani K, Toyoshima Y,
Nakamura Y
. Personalized immunotherapy in cancer precision medicine. Cancer Biol Med. 2021 Aug 09.
PMID:
34369137
; PMCID:
PMC8610159
.
Citations:
24
Fields:
Neo
Neoplasms
Morisaki T, Morisaki T, Kubo M, Onishi H, Hirano T, Morisaki S, Eto M, Monji K, Takeuchi A, Nakagawa S, Tanaka H, Koya N, Umebayashi M, Tsujimura K, Yew PY, Yoshimura S, Kiyotani K,
Nakamura Y
. Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis. Anticancer Res. 2021 Aug; 41(8):4101-4115.
PMID:
34281881
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Yoshimaru T,
Nakamura Y
, Katagiri T. Functional genomics for breast cancer drug target discovery. J Hum Genet. 2021 Sep; 66(9):927-935.
PMID:
34285339
; PMCID:
PMC8384626
.
Citations:
6
Fields:
Gen
Genetics
Translation:
Humans
Morisaki T, Kubo M, Umebayashi M, Yew PY, Yoshimura S, Park JH, Kiyotani K, Kai M, Yamada M, Oda Y,
Nakamura Y
, Morisaki T, Nakamura M. Neoantigens elicit T cell responses in breast cancer. Sci Rep. 2021 06 30; 11(1):13590.
PMID:
34193879
; PMCID:
PMC8245657
.
Citations:
18
Fields:
Sci
Science
Translation:
Humans
Cells
CT
Clinical Trials
Kiyotani K, Toyoshima Y,
Nakamura Y
. Immunogenomics in personalized cancer treatments. J Hum Genet. 2021 Sep; 66(9):901-907.
PMID:
34193979
.
Citations:
5
Fields:
Gen
Genetics
Translation:
Humans
Pittella-Silva F, Kimura Y, Low SK,
Nakamura Y
, Motoya M. Amplification of mutant KRASG12D in a patient with advanced metastatic pancreatic adenocarcinoma detected by liquid biopsy: A case report. Mol Clin Oncol. 2021 Sep; 15(3):172.
PMID:
34276991
; PMCID:
PMC8278405
.
Citations:
1
Watanabe K,
Nakamura Y
, Low SK. Clinical implementation and current advancement of blood liquid biopsy in cancer. J Hum Genet. 2021 Sep; 66(9):909-926.
PMID:
34088974
.
Citations:
9
Fields:
Gen
Genetics
Translation:
Humans
Peng K, Safonova Y, Shugay M, Popejoy AB, Rodriguez OL, Breden F, Brodin P, Burkhardt AM, Bustamante C, Corcoran MM, Duffy D, Greiff V, Liu X, Quintana-Murci L, Rossetti M, Xie J, Yaari G, Zhang W, Abedalthagafi MS, Adekoya KO, Ahmed RA, Chang WC, Gray C,
Nakamura Y
, Lees WD, Khatri P, Alachkar H, Scheepers C, Watson CT, Karlsson Hedestam GB, Mangul S, Cao-Lormeau VM, Fuentes-Guajardo M, Fujita R, Jönsson VD. Diversity in immunogenomics: the value and the challenge. Nat Methods. 2021 06; 18(6):588-591.
PMID:
34002093
; PMCID:
PMC8842483
.
Citations:
23
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Humans
Cells
Wei T, Xia M, Kiyotani K, Li N, Zeng C, Deng C, Jiang J, Harada M,
Agrawal N
, Li L, Qi H,
Nakamura Y
, Ren L, Leisegang M. Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma. Oncoimmunology. 2021 05 25; 10(1):1929726.
PMID:
34104546
; PMCID:
PMC8158031
.
Citations:
17
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Yamaguchi K, Kasajima R, Takane K, Hatakeyama S, Shimizu E, Yamaguchi R, Katayama K, Arai M, Ishioka C, Iwama T, Kaneko S, Matsubara N, Moriya Y, Nomizu T, Sugano K, Tamura K, Tomita N, Yoshida T, Sugihara K,
Nakamura Y
, Miyano S, Imoto S, Furukawa Y, Ikenoue T. Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome. J Hum Genet. 2021 Nov; 66(11):1053-1060.
PMID:
33958709
.
Citations:
9
Fields:
Gen
Genetics
Translation:
Humans
Cells
PH
Public Health
Suzuki T, Koike Y, Ashikawa K, Otomo N, Takahashi A, Aoi T, Kamatani N,
Nakamura Y
, Kubo M, Kamatani Y, Momozawa Y, Terao C, Yamakawa K. Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24. Epilepsia. 2021 06; 62(6):1391-1400.
PMID:
33913524
.
Citations:
3
Fields:
Bra
Brain
Neu
Neurology
Translation:
Humans
Cells
Schreiber K, Hyjek E,
Krausz T
, Spiotto MT, Steiner M, Idel C, Booras H, Beck-Engeser G, Riederer J, Wolf SP,
Karrison T
, Jensen E,
Weichselbaum RR
,
Nakamura Y
, Yew PY, Lambert PF, Kurita T, Kiyotani K,
Schreiber H
, Böttinger P, Willimsky G, Leisegang M. Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens. Carcinogenesis. 2020 11 13; 41(11):1605-1615.
PMID:
32221533
; PMCID:
PMC7896110
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Takeuchi S, Kagabu M, Shoji T, Nitta Y, Sugiyama T, Sato J,
Nakamura Y
. Anti-cancer immunotherapy using cancer-derived multiple epitope-peptides cocktail vaccination clinical studies in patients with refractory/persistent disease of uterine cervical cancer and ovarian cancer [phase 2]. Oncoimmunology. 2020 11 11; 9(1):1838189.
PMID:
33235818
; PMCID:
PMC7671072
.
Citations:
7
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Translation:
Humans
PH
Public Health
CT
Clinical Trials
Chin YM, Takahashi Y, Chan HT, Otaki M, Fujishima M, Shibayama T, Miki Y, Ueno T,
Nakamura Y
, Low SK. Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer. Cancer Sci. 2021 Jan; 112(1):454-464.
PMID:
33075187
; PMCID:
PMC7780051
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Ikeda Y, Sato S, Yabuno A, Shintani D, Ogasawara A, Miwa M, Zewde M, Miyamoto T, Fujiwara K,
Nakamura Y
, Hasegawa K. High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo. J Gynecol Oncol. 2020 Nov; 31(6):e93.
PMID:
33078598
; PMCID:
PMC7593222
.
Citations:
6
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Fujimori D, Kinoshita J, Yamaguchi T,
Nakamura Y
, Gunjigake K, Ohama T, Sato K, Yamamoto M, Tsukamoto T, Nomura S, Ohta T, Fushida S. Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer. BMC Cancer. 2020 Oct 20; 20(1):1014.
PMID:
33081727
; PMCID:
PMC7574408
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Chung S, Kijima K, Kudo A, Fujisawa Y, Harada Y, Taira A, Takamatsu N, Miyamoto T, Matsuo Y,
Nakamura Y
. Correction: Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor. Oncotarget. 2020 Oct 13; 11(41):3749-3750.
PMID:
33110482
; PMCID:
PMC7566805
.
Citations:
Fields:
Neo
Neoplasms
Vougiouklakis T, Bernard BJ, Nigam N, Burkitt K,
Nakamura Y
, Saloura V. Clinicopathologic significance of protein lysine methyltransferases in cancer. Clin Epigenetics. 2020 10 13; 12(1):146.
PMID:
33050946
; PMCID:
PMC7557092
.
Citations:
6
Fields:
Gen
Genetics
Translation:
Humans
Cells
Suzuki T, Suzuki T, Yoshimura Y, Yahata M, Yew PY, Nakamura T,
Nakamura Y
, Park JH, Matsuo R. Detection of circulating tumor DNA in patients of operative colorectal and gastric cancers. Oncotarget. 2020 Aug 25; 11(34):3198-3207.
PMID:
32922660
; PMCID:
PMC7456613
.
Citations:
8
Fields:
Neo
Neoplasms
Jinawath N, Shiao MS, Chanpanitkitchote P, Svasti J, Furukawa Y,
Nakamura Y
. Enhancement of Migration and Invasion of Gastric Cancer Cells by IQGAP3. Biomolecules. 2020 08 17; 10(8).
PMID:
32824461
; PMCID:
PMC7465220
.
Citations:
12
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Chan HT, Chin YM,
Nakamura Y
, Low SK. Clonal Hematopoiesis in Liquid Biopsy: From Biological Noise to Valuable Clinical Implications. Cancers (Basel). 2020 Aug 14; 12(8).
PMID:
32823942
; PMCID:
PMC7463455
.
Citations:
58
Toyoshima Y, Nemoto K, Matsumoto S,
Nakamura Y
, Kiyotani K. SARS-CoV-2 genomic variations associated with mortality rate of COVID-19. J Hum Genet. 2020 Dec; 65(12):1075-1082.
PMID:
32699345
; PMCID:
PMC7375454
.
Citations:
201
Fields:
Gen
Genetics
Translation:
Humans
Cells
PH
Public Health
Morisaki T, Hikichi T, Onishi H, Morisaki T, Kubo M, Hirano T, Yoshimura S, Kiyotani K,
Nakamura Y
. Intranodal Administration of Neoantigen Peptide-loaded Dendritic Cell Vaccine Elicits Epitope-specific T Cell Responses and Clinical Effects in a Patient with Chemorefractory Ovarian Cancer with Malignant Ascites. Immunol Invest. 2021 Jul; 50(5):562-579.
PMID:
32660279
.
Citations:
13
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
PH
Public Health
Pittella-Silva F, Chin YM, Chan HT, Nagayama S, Miyauchi E, Low SK,
Nakamura Y
. Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy? Clin Chem. 2020 07 01; 66(7):946-957.
PMID:
32516802
.
Citations:
36
Fields:
Che
Chemistry
Translation:
Humans
Ikenoue T, Arai M, Ishioka C, Iwama T, Kaneko S, Matsubara N, Moriya Y, Nomizu T, Sugano K, Tamura K, Tomita N, Yoshida T, Sugihara K, Naruse H, Yamaguchi K, Nojima M,
Nakamura Y
, Furukawa Y, Japanese society for cancer of the colon and rectum (JSCCR). Correction: Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients. J Hum Genet. 2020 07; 65(7):633.
PMID:
32341458
.
Citations:
Fields:
Gen
Genetics
Chan HT, Nagayama S, Chin YM, Otaki M, Hayashi R, Kiyotani K, Fukunaga Y, Ueno M,
Nakamura Y
, Low SK. Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy. Mol Oncol. 2020 08; 14(8):1719-1730.
PMID:
32449983
; PMCID:
PMC7400786
.
Citations:
41
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Ishigaki K, Akiyama M, Kanai M, Takahashi A, Kawakami E, Sugishita H, Sakaue S, Matoba N, Low SK, Okada Y, Terao C, Amariuta T, Gazal S, Kochi Y, Horikoshi M, Suzuki K, Ito K, Koyama S, Ozaki K, Niida S, Sakata Y, Sakata Y, Kohno T, Shiraishi K, Momozawa Y, Hirata M, Matsuda K, Ikeda M, Iwata N, Ikegawa S, Kou I, Tanaka T, Nakagawa H, Suzuki A, Hirota T, Tamari M, Chayama K, Miki D, Mori M, Nagayama S, Daigo Y, Miki Y, Katagiri T, Ogawa O, Obara W, Ito H, Yoshida T, Imoto I, Takahashi T, Tanikawa C, Suzuki T, Sinozaki N, Minami S, Yamaguchi H, Asai S, Takahashi Y, Yamaji K, Takahashi K, Fujioka T, Takata R, Yanai H, Masumoto A, Koretsune Y, Kutsumi H, Higashiyama M, Murayama S, Minegishi N, Suzuki K, Tanno K, Shimizu A, Yamaji T, Iwasaki M, Sawada N, Uemura H, Tanaka K, Naito M, Sasaki M, Wakai K, Tsugane S, Yamamoto M, Yamamoto K, Murakami Y,
Nakamura Y
, Raychaudhuri S, Inazawa J, Yamauchi T, Kadowaki T, Kubo M, Kamatani Y. Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nat Genet. 2020 07; 52(7):669-679.
PMID:
32514122
; PMCID:
PMC7968075
.
Citations:
206
Fields:
Gen
Genetics
Translation:
Humans
Saloura V, Vougiouklakis T, Bao R, Kim S, Baek S, Zewde M, Bernard B, Burkitt K, Nigam N,
Izumchenko E
, Dohmae N, Hamamoto R,
Nakamura Y
. WHSC1 monomethylates histone H1 and induces stem-cell like features in squamous cell carcinoma of the head and neck. Neoplasia. 2020 08; 22(8):283-293.
PMID:
32497898
; PMCID:
PMC7265065
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kiyotani K, Toyoshima Y, Nemoto K,
Nakamura Y
. Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2. J Hum Genet. 2020 Jul; 65(7):569-575.
PMID:
32372051
; PMCID:
PMC7200206
.
Citations:
88
Fields:
Gen
Genetics
Translation:
Humans
Cells
Horiuchi H, Agetsuma M, Ishida J,
Nakamura Y
, Lawrence Cheung D, Nanasaki S, Kimura Y, Iwata T, Takahashi K, Sawada K, Nabekura J. CMOS-based bio-image sensor spatially resolves neural activity-dependent proton dynamics in the living brain. Nat Commun. 2020 02 05; 11(1):712.
PMID:
32024837
; PMCID:
PMC7002452
.
Citations:
6
Fields:
Bio
Biology
Sci
Science
Translation:
Animals
Shibayama T, Low SK, Ono M, Kobayashi T, Kobayashi K, Fukada I, Ito Y, Ueno T, Ohno S,
Nakamura Y
, Takahashi S. Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer. Breast Cancer Res Treat. 2020 Apr; 180(2):331-341.
PMID:
32020432
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Kothari S, Artz AS, Lee SM, Fulton N, Park JH,
Stock W
,
Larson RA
,
Odenike O
,
Kline J
,
LaBelle J
,
Kosuri S
,
Riedell P
,
Nakamura Y
,
Bishop MR
, Liu H. Dose escalation prophylactic donor lymphocyte infusion after T-cell depleted matched related donor allogeneic hematopoietic cell transplantation is feasible and results in higher donor chimerism, faster immune re-constitution, and prolonged progression-free survival. Bone Marrow Transplant. 2020 06; 55(6):1161-1168.
PMID:
31992847
.
Citations:
9
Fields:
Tra
Transplantation
Translation:
Humans
Cells
CT
Clinical Trials
Yoshimaru T, Matsushita Y, Matsuo T, Park JH, Sasa M, Miyoshi Y, Katagiri T, Kimura R, Ono M,
Nakamura Y
. The GALNT6-LGALS3BP axis promotes breast cancer cell growth. Int J Oncol. 2020 Feb; 56(2):581-595.
PMID:
31894262
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Low SK, Chin YM, Ito H, Matsuo K, Tanikawa C, Matsuda K, Saito H, Sakurai-Yageta M, Nakaya N, Shimizu A, Nishizuka SS, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Takezaki T, Suzuki S, Naito M, Wakai K, Kamatani Y, Momozawa Y, Murakami Y, Inazawa J,
Nakamura Y
, Kubo M, Katagiri T, Miki Y. Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population. Sci Rep. 2019 11 22; 9(1):17332.
PMID:
31757997
; PMCID:
PMC6874604
.
Citations:
7
Fields:
Sci
Science
Translation:
Humans
Stefka AT, Johnson D, Rosebeck S, Park JH,
Nakamura Y
,
Jakubowiak AJ
. Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models. Cancer Med. 2020 01; 9(1):324-334.
PMID:
31714026
; PMCID:
PMC6943155
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ikenoue T, Arai M, Ishioka C, Iwama T, Kaneko S, Matsubara N, Moriya Y, Nomizu T, Sugano K, Tamura K, Tomita N, Yoshida T, Sugihara K, Naruse H, Yamaguchi K, Nojima M,
Nakamura Y
, Furukawa Y, Japanese society for cancer of the colon and rectum (JSCCR). Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients. J Hum Genet. 2019 Dec; 64(12):1187-1194.
PMID:
31588121
.
Citations:
6
Fields:
Gen
Genetics
Translation:
Humans
Saloura V,
Izumchenko E
, Zuo Z, Bao R, Korzinkin M, Ozerov I, Zhavoronkov A, Sidransky D, Bedi A, Hoque MO, Koeppen H, Keck MK, Khattri A, London N, Kotlov N, Fatima A, Vougiouklakis T,
Nakamura Y
,
Lingen M
,
Agrawal N
, Savage PA,
Kron S
, Kline J, Kowanetz M, Seiwert TY. Immune profiles in primary squamous cell carcinoma of the head and neck. Oral Oncol. 2019 09; 96:77-88.
PMID:
31422218
; PMCID:
PMC7893610
.
Citations:
41
Fields:
Neo
Neoplasms
Translation:
Humans
Low SK,
Nakamura Y
. The road map of cancer precision medicine with the innovation of advanced cancer detection technology and personalized immunotherapy. Jpn J Clin Oncol. 2019 Jul 01; 49(7):596-603.
PMID:
31135897
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Goetz MP, Suman VJ,
Nakamura Y
, Kiyotani K, Jordan VC, Ingle JN. Tamoxifen Metabolism and Breast Cancer Recurrence: A Question Unanswered by CYPTAM. J Clin Oncol. 2019 08 01; 37(22):1982-1983.
PMID:
31211604
; PMCID:
PMC6675592
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Sugiyama T, Tajiri T, Fujita H, Hiraiwa S, Toguchi S, Nomura N, Machida T, Suga A,
Nakamura Y
, Nakagawa T, Yamada S, Iwazaki M, Nakamura N. A biosafety algorithm for the protection of pathology staff during intraoperative examinations of pulmonary lesions. Pathol Int. 2019 Apr; 69(4):211-218.
PMID:
30990957
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Matsuda T, Miyauchi E, Hsu YW, Nagayama S, Kiyotani K, Zewde M, Park JH, Kato T, Harada M, Matsui S, Ueno M, Fukuda K, Suzuki N, Hazama S, Nagano H, Takeuchi H, Vigneswaran WT, Kitagawa Y,
Nakamura Y
. TCR sequencing analysis of cancer tissues and tumor draining lymph nodes in colorectal cancer patients. Oncoimmunology. 2019; 8(6):e1588085.
PMID:
31069156
; PMCID:
PMC6492974
.
Citations:
16
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Danese E, Raimondi S, Montagnana M, Tagetti A, Langaee T, Borgiani P, Ciccacci C, Bourgeois S, Deloukas P, Caldwell MD, Burmester JK, Berg RL, Cavallari LH, Drozda K, Huang M, Zhao LZ, Cen HJ,
Nakamura Y
, Mushiroda T, Gong IY, Kim RB, Hirai K, Itoh K, Giontella A, Gwak HS, Lee KE, Minuz P, Lee MTM, Lubitz SA, Scott S, Mazzaccara C, Sacchetti L, Pathare A, Krishnamoorthy R, Paldi A, Kutala VK, Perini J, Denny JC, Ramirez AH, Mittal B, Rathore SS, Sagreiya H, Altman R, Shahin MHA, Khalifa SI, Limdi NA, Rivers C, Shendre A, Dillon C, Suriapranata IM, Zhou HH, Tan SL, Tatarunas V, Lesauskaite V, Zhang Y, Maitland-van der Zee AH, Verhoef TI, de Boer A, Taljaard M, Zambon CF, Pengo V, Zhang JE, Pirmohamed M, Johnson JA, Fava C, Carcas AJ, Borobia AM, Tong HY, Dávila-Fajardo C, Rodrigues Botton M, Gonzalez-Conejero R, Roldan V, Isaza C, Beltrán L, Jiménez-Varo E, Cañadas-Garre M, Kringen MK, Haug KBF, Genç E, Özer M, Siguret V, Loriot MA, Suarez-Kurtz G. Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals. Clin Pharmacol Ther. 2019 06; 105(6):1477-1491.
PMID:
30506689
; PMCID:
PMC6542461
.
Citations:
11
Fields:
Dru
Drug Therapy
Pha
Pharmacology
Translation:
Humans
Miyauchi E, Matsuda T, Kiyotani K, Low SK, Hsu YW, Tsukita Y, Ichinose M, Sakurada A, Okada Y, Saito R,
Nakamura Y
. Significant differences in T cell receptor repertoires in lung adenocarcinomas with and without epidermal growth factor receptor mutations. Cancer Sci. 2019 Mar; 110(3):867-874.
PMID:
30582659
; PMCID:
PMC6398877
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Ren L, Deng B, Matsuda T, Kiyotani K, Kato T, Harada M, Park JH, Saloura V, Seiwert T,
Vokes E
,
Agrawal N
,
Nakamura Y
, Leisegang M. Identification of neoantigen-specific T cells and their targets: implications for immunotherapy of head and neck squamous cell carcinoma. Oncoimmunology. 2019; 8(4):e1568813.
PMID:
30906664
; PMCID:
PMC6422382
.
Citations:
23
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Ren L, Deng B, Saloura V, Park JH,
Nakamura Y
. MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells. Oncol Rep. 2019 Apr; 41(4):2540-2548.
PMID:
30720113
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Chlenski A
, Park C, Dobratic M, Salwen HR,
Budke B
, Park JH, Miller R,
Applebaum MA
, Wilkinson E,
Nakamura Y
,
Connell PP
,
Cohn SL
. Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma. Mol Cancer Ther. 2019 03; 18(3):507-516.
PMID:
30674566
; PMCID:
PMC6398941
.
Citations:
16
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Sugiyama T, Tajiri T, Fujita H, Hiraiwa S, Toguchi S, Nomura N, Machida T,
Nakamura Y
, Nakagawa T, Yamada S, Iwazaki M, Nakamura N. Diagnostic utility and pitfalls of intraoperative pulmonary imprint cytology based on final pathological diagnoses. Cytopathology. 2019 01; 30(1):74-81.
PMID:
30417954
.
Citations:
Fields:
Cel
Cell Biology
Pat
Pathology
Translation:
Humans
Tanikawa C, Kamatani Y, Toyoshima O, Sakamoto H, Ito H, Takahashi A, Momozawa Y, Hirata M, Fuse N, Takai-Igarashi T, Shimizu A, Sasaki M, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Naito M, Hishida A, Wakai K, Furusyo N, Murakami Y,
Nakamura Y
, Imoto I, Inazawa J, Oze I, Sato N, Tanioka F, Sugimura H, Hirose H, Yoshida T, Matsuo K, Kubo M, Matsuda K. Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21. Cancer Sci. 2018 Dec; 109(12):4015-4024.
PMID:
30281874
; PMCID:
PMC6272082
.
Citations:
30
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Deng B, Tarhan YE, Ueda K, Ren L, Katagiri T, Park JH,
Nakamura Y
. Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells. Neoplasia. 2018 10; 20(10):1038-1044.
PMID:
30208353
; PMCID:
PMC6138801
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Saloura V, Vougiouklakis T, Burkitt K,
Nakamura Y
, Hager GL, van Waes C. Corrigendum to "The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck" [Oral Oncol. 81 (2018) 100-108]. Oral Oncol. 2018 Nov; 86:318.
PMID:
30201513
; PMCID:
PMC6691895
.
Citations:
Fields:
Neo
Neoplasms
Kato Y, Zembutsu H, Takata R, Matsuura T, Kato R, Kanehira M, Iwasaki K, Yamada N, Katagiri T, Sugai T, Fujioka T,
Nakamura Y
, Obara W. A prospective study to examine the accuracies and efficacies of prediction systems for response to neoadjuvant chemotherapy for muscle invasive bladder cancer. Oncol Lett. 2018 Nov; 16(5):5775-5784.
PMID:
30333861
; PMCID:
PMC6176418
.
Citations:
Nakamoto H, Amaya Y, Komatsu T, Suzuki T, Dohmae N,
Nakamura Y
, Jantan I, Miyata Y. Stimulation of the ATPase activity of Hsp90 by zerumbone modification of its cysteine residues destabilizes its clients and causes cytotoxicity. Biochem J. 2018 08 16; 475(15):2559-2576.
PMID:
30045873
.
Citations:
3
Fields:
Bio
Biochemistry
Translation:
Animals
Cells
Innocenti F, Owzar K, Jiang C, Etheridge AS, Sibley AB, Mulkey F, Niedzwiecki D, Glubb D, Neel N,
Talamonti MS
, Bentrem DJ, Seiser E, Yeh JJ, Van Loon K, McLeod H,
Ratain MJ
,
Kindler HL
, Venook AP,
Nakamura Y
, Kubo M, Petersen GM, Bamlet WR, McWilliams RR, Gordân R. The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation. PLoS One. 2018; 13(8):e0202272.
PMID:
30107003
; PMCID:
PMC6091939
.
Citations:
6
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
CT
Clinical Trials
Aue G, Sun C, Liu D, Park JH, Pittaluga S, Tian X, Lee E, Soto S, Valdez J, Maric I, Stetler-Stevenson M, Yuan C,
Nakamura Y
, Muranski P, Wiestner A. Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia. J Immunol. 2018 10 01; 201(7):1967-1974.
PMID:
30104242
; PMCID:
PMC6143435
.
Citations:
14
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
PH
Public Health
CT
Clinical Trials
Vougiouklakis T, Saloura V, Park JH, Takamatsu N, Miyamoto T,
Nakamura Y
, Matsuo Y. Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX. Oncotarget. 2018 Aug 07; 9(61):31820-31831.
PMID:
30159125
; PMCID:
PMC6112750
.
Citations:
9
Fields:
Neo
Neoplasms
Ko TM, Kiyotani K, Chang JS, Park JH, Yin Yew P, Chen YT, Wu JY,
Nakamura Y
. Immunoglobulin profiling identifies unique signatures in patients with Kawasaki disease during intravenous immunoglobulin treatment. Hum Mol Genet. 2018 08 01; 27(15):2671-2677.
PMID:
29771320
; PMCID:
PMC6048982
.
Citations:
7
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Obara W, Hara I, Kato Y, Kato R, Inoue K, Sato F, Mimata H,
Nakamura Y
, Fujioka T. Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer. Cancer Immunol Immunother. 2018 Sep; 67(9):1371-1380.
PMID:
29971464
; PMCID:
PMC11028097
.
Citations:
8
Fields:
All
Allergy and Immunology
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
CT
Clinical Trials
Li HK, Sugyo A, Tsuji AB, Morokoshi Y, Minegishi K, Nagatsu K, Kanda H, Harada Y, Nagayama S, Katagiri T,
Nakamura Y
, Higashi T, Hasegawa S. a-particle therapy for synovial sarcoma in the mouse using an astatine-211-labeled antibody against frizzled homolog 10. Cancer Sci. 2018 Jul; 109(7):2302-2309.
PMID:
29952132
; PMCID:
PMC6029834
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Iwao-Fukukawa C, Mori M, Tsunoda T, Katagiri T,
Nakamura Y
, Giraudet AL, Cassier PA, Garin G, Badel JN, Kryza D, Chabaud S, Gilles-Afchain L, Clapisson G, Desuzinges C, Sarrut D, Halty A, Italiano A, Alberti L, Cropet C, Baconnier S, Berge-Montamat S, Pérol D, Blay JY. A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients. BMC Cancer. 2018 Jun 08; 18(1):646.
PMID:
29884132
; PMCID:
PMC5994021
.
Citations:
35
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Zewde M, Kiyotani K, Park JH,
Fang H
, Yap KL, Yew PY, Alachkar H, Kato T, Mai TH, Ikeda Y, Matsuda T, Liu X, Ren L, Deng B, Harada M,
Nakamura Y
. The era of immunogenomics/immunopharmacogenomics. J Hum Genet. 2018 Jul; 63(8):865-875.
PMID:
29785006
.
Citations:
8
Fields:
Gen
Genetics
Translation:
Humans
Nakamura Y
, Mukai M, Hiraiwa S, Kishima K, Sugiyama T, Tajiri T, Yamada S, Iwazaki M. Free-floating cancer cells in lymph node sinuses of hilar lymph node-positive patients with non-small cell lung cancer. Mol Med Rep. 2018 Jul; 18(1):1081-1087.
PMID:
29767232
.
Citations:
1
Fields:
Mol
Molecular Biology
Translation:
Humans
CT
Clinical Trials
Tanikawa C, Kamatani Y, Takahashi A, Momozawa Y, Leveque K, Nagayama S, Mimori K, Mori M, Ishii H, Inazawa J, Yasuda J, Tsuboi A, Shimizu A, Sasaki M, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Naito M, Wakai K, Koyama T, Takezaki T, Yuji K, Murakami Y,
Nakamura Y
, Kubo M, Matsuda K. GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12. Carcinogenesis. 2018 05 03; 39(5):652-660.
PMID:
29471430
.
Citations:
30
Fields:
Neo
Neoplasms
Translation:
Humans
Saloura V, Vougiouklakis T, Sievers C, Burkitt K,
Nakamura Y
, Hager G, van Waes C. The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck. Oral Oncol. 2018 06; 81:100-108.
PMID:
29884408
; PMCID:
PMC6681457
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Matsuda T, Park JH, Ren L, Kato T, Ikeda Y, Harada M, Kiyotani K,
Lengyel E
,
Fleming GF
,
Nakamura Y
, Leisegang M. Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor-Engineered T Cells for Ovarian Cancer. Clin Cancer Res. 2018 11 01; 24(21):5357-5367.
PMID:
29720506
.
Citations:
41
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hasegawa K, Ikeda Y, Kunugi Y, Kurosaki A, Imai Y, Kohyama S, Nagao S, Kozawa E, Yoshida K, Tsunoda T,
Nakamura Y
, Fujiwara K. Phase I Study of Multiple Epitope Peptide Vaccination in Patients With Recurrent or Persistent Cervical Cancer. J Immunother. 2018 May; 41(4):201-207.
PMID:
29432282
.
Citations:
15
Fields:
All
Allergy and Immunology
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
PH
Public Health
CT
Clinical Trials
Deng B, Park JH, Ren L, Yew PY, Kiyotani K,
Antic T
, O'Connor K,
O'Donnell PH
,
Nakamura Y
. CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors. Cancer Rep (Hoboken). 2018 06; 1(1):e1002.
PMID:
32729250
; PMCID:
PMC7941587
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Santa-Maria CA, Kato T, Park JH, Kiyotani K, Rademaker A, Shah AN, Gross L, Blanco LZ, Jain S, Flaum L, Tellez C, Stein R, Uthe R, Gradishar WJ, Cristofanilli M,
Nakamura Y
, Giles FJ. A pilot study of durvalumab and tremelimumab and immunogenomic dynamics in metastatic breast cancer. Oncotarget. 2018 Apr 10; 9(27):18985-18996.
PMID:
29721177
; PMCID:
PMC5922371
.
Citations:
44
Fields:
Neo
Neoplasms
Kiyotani K, Chan HT,
Nakamura Y
. Immunopharmacogenomics towards personalized cancer immunotherapy targeting neoantigens. Cancer Sci. 2018 Mar; 109(3):542-549.
PMID:
29288513
; PMCID:
PMC5834780
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Nakatake R, Kaibori M,
Nakamura Y
, Tanaka Y, Matushima H, Okumura T, Murakami T, Ino Y, Todo T, Kon M. Third-generation oncolytic herpes simplex virus inhibits the growth of liver tumors in mice. Cancer Sci. 2018 Mar; 109(3):600-610.
PMID:
29288515
; PMCID:
PMC5834814
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Tanikawa C, Ueda K, Suzuki A, Iida A, Nakamura R, Atsuta N, Tohnai G, Sobue G, Saichi N, Momozawa Y, Kamatani Y, Kubo M, Yamamoto K,
Nakamura Y
, Matsuda K. Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility. Cell Rep. 2018 02 06; 22(6):1473-1483.
PMID:
29425503
.
Citations:
50
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Vougiouklakis T,
Nakamura Y
, Saloura V. Critical roles of protein methyltransferases and demethylases in the regulation of embryonic stem cell fate. Epigenetics. 2017; 12(12):1015-1027.
PMID:
29099285
; PMCID:
PMC5810763
.
Citations:
9
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Kato T, Matsuda T, Ikeda Y, Park JH, Yoshimura S, Hikichi T, Harada M, Zewde M, Sato S, Hasegawa K, Kiyotani K,
Nakamura Y
, Leisegang M. Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells. Oncotarget. 2018 Feb 16; 9(13):11009-11019.
PMID:
29541393
; PMCID:
PMC5834292
.
Citations:
28
Fields:
Neo
Neoplasms
Liu H
, Zha Y,
Choudhury N
, Malnassy G, Fulton N, Green M, Park JH,
Nakamura Y
,
Larson RA
, Salazar AM,
Odenike O
,
Gajewski TF
,
Stock W
. WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia. Exp Hematol Oncol. 2018; 7:1.
PMID:
29344432
; PMCID:
PMC5765712
.
Citations:
10
Liu D, Ray B, Neavin DR, Zhang J, Athreya AP, Biernacka JM, Bobo WV, Hall-Flavin DK, Skime MK, Zhu H, Jenkins GD, Batzler A, Kalari KR, Boakye-Agyeman F, Matson WR, Bhasin SS, Mushiroda T,
Nakamura Y
, Kubo M, Iyer RK, Wang L, Frye MA, Kaddurah-Daouk R, Weinshilboum RM. Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics. Transl Psychiatry. 2018 01 10; 8(1):10.
PMID:
29317604
; PMCID:
PMC5802574
.
Citations:
40
Fields:
Psy
Psychiatry
Translation:
Humans
Cells
Hijikata Y, Okazaki T, Tanaka Y, Murahashi M, Yamada Y, Yamada K, Takahashi A, Inoue H, Kishimoto J, Nakanishi Y, Oda Y,
Nakamura Y
, Tani K. A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors. PLoS One. 2018; 13(1):e0187878.
PMID:
29293510
; PMCID:
PMC5749706
.
Citations:
7
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
CT
Clinical Trials
Low SK, Zembutsu H,
Nakamura Y
. Breast cancer: The translation of big genomic data to cancer precision medicine. Cancer Sci. 2018 Mar; 109(3):497-506.
PMID:
29215763
; PMCID:
PMC5834810
.
Citations:
45
Fields:
Neo
Neoplasms
Translation:
Humans
Ren L, Matsuda T, Deng B, Kiyotani K, Kato T, Park JH, Seiwert TY,
Vokes EE
,
Agrawal N
,
Nakamura Y
. Similarity and difference in tumor-infiltrating lymphocytes in original tumor tissues and those of in vitro expanded populations in head and neck cancer. Oncotarget. 2018 Jan 09; 9(3):3805-3814.
PMID:
29423084
; PMCID:
PMC5790501
.
Citations:
4
Fields:
Neo
Neoplasms
Kiyotani K, Mai TH, Yamaguchi R, Yew PY, Kulis M, Orgel K, Imoto S, Miyano S, Burks AW,
Nakamura Y
. Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy. J Hum Genet. 2018 Feb; 63(2):239-248.
PMID:
29192240
.
Citations:
15
Fields:
Gen
Genetics
Translation:
Humans
Vougiouklakis T, Bao R,
Nakamura Y
, Saloura V. Protein methyltransferases and demethylases dictate CD8+ T-cell exclusion in squamous cell carcinoma of the head and neck. Oncotarget. 2017 Dec 22; 8(68):112797-112808.
PMID:
29348866
; PMCID:
PMC5762551
.
Citations:
8
Fields:
Neo
Neoplasms
Sato S, Nakamura T, Katagiri T, Tsuchikawa T, Kushibiki T, Hontani K, Takahashi M, Inoko K, Takano H, Abe H, Takeuchi S, Ono M, Kuwabara S, Umemoto K, Suzuki T, Sato O,
Nakamura Y
, Hirano S. Molecular targeting of cell-permeable peptide inhibits pancreatic ductal adenocarcinoma cell proliferation. Oncotarget. 2017 Dec 26; 8(69):113662-113672.
PMID:
29371937
; PMCID:
PMC5768354
.
Citations:
3
Fields:
Neo
Neoplasms
Tanaka H, Hazama S, Iida M, Tsunedomi R, Takenouchi H, Nakajima M, Tokumitsu Y, Kanekiyo S, Shindo Y, Tomochika S, Tokuhisa Y, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Hamamoto Y, Fujita Y, Tanaka H, Tahara K, Shimizu R, Okuno K, Fujita K, Kuroda M,
Nakamura Y
, Nagano H. miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer. Cancer Sci. 2017 Nov; 108(11):2229-2238.
PMID:
28859241
; PMCID:
PMC5666028
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
CT
Clinical Trials
Deng X, Hamamoto R, Vougiouklakis T, Wang R, Yoshioka Y, Suzuki T, Dohmae N, Matsuo Y, Park JH,
Nakamura Y
. Critical roles of SMYD2-mediated ß-catenin methylation for nuclear translocation and activation of Wnt signaling. Oncotarget. 2017 Aug 22; 8(34):55837-55847.
PMID:
28915556
; PMCID:
PMC5593527
.
Citations:
22
Fields:
Neo
Neoplasms
Takeichi H, Yamada S,
Nakamura Y
, Tajiri T, Iwazaki M. Video-assisted segmental resection of an intrapulmonary bronchogenic cyst mimicking a middle mediastinal cystic tumor. Asian J Endosc Surg. 2017 Nov; 10(4):404-406.
PMID:
28677870
.
Citations:
Fields:
Dia
Diagnostic Imaging
Gen
General Surgery
Translation:
Humans
Kato T, Park JH, Kiyotani K, Ikeda Y, Miyoshi Y,
Nakamura Y
. Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers. Oncotarget. 2017 Sep 22; 8(37):62029-62038.
PMID:
28977923
; PMCID:
PMC5617483
.
Citations:
12
Fields:
Neo
Neoplasms
Kato T, Park JH, Kiyotani K, Ikeda Y, Miyoshi Y,
Nakamura Y
. Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers. Oncotarget. 2017 Jun 28.
PMID:
28706143
.
Citations:
Fujiwara Y, Sugimura K, Miyata H, Omori T, Yano M, Nakano H, Mochizuki C, Shimizu K, Saito H, Ashida K, Honjyo S,
Nakamura Y
. A Pilot Study of Post-Operative Adjuvant Vaccine for Advanced Gastric Cancer. Yonago Acta Med. 2017 06; 60(2):101-105.
PMID:
28701892
; PMCID:
PMC5502221
.
Citations:
6
Fields:
Med
Medicine (General)
Obara W, Sato F, Takeda K, Kato R, Kato Y, Kanehira M, Takata R, Mimata H, Sugai T,
Nakamura Y
, Fujioka T. Phase I clinical trial of cell division associated 1 (CDCA1) peptide vaccination for castration resistant prostate cancer. Cancer Sci. 2017 Jul; 108(7):1452-1457.
PMID:
28498618
; PMCID:
PMC5497926
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Yoshioka Y, Suzuki T, Matsuo Y, Tsurita G, Watanabe T, Dohmae N,
Nakamura Y
, Hamamoto R. Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization. Cancer Med. 2017 Jul; 6(7):1665-1672.
PMID:
28639750
; PMCID:
PMC5504314
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Matsuda T, Kato T, Kiyotani K, Tarhan YE, Saloura V, Chung S, Ueda K,
Nakamura Y
, Park JH. p53-independent p21 induction by MELK inhibition. Oncotarget. 2017 Jun 15.
PMID:
28636549
.
Citations:
Matsuda T, Kato T, Kiyotani K, Tarhan YE, Saloura V, Chung S, Ueda K,
Nakamura Y
, Park JH. p53-independent p21 induction by MELK inhibition. Oncotarget. 2017 Aug 29; 8(35):57938-57947.
PMID:
28938528
; PMCID:
PMC5601624
.
Citations:
24
Fields:
Neo
Neoplasms
Tamakoshi A, Nakamura K, Ukawa S, Okada E, Hirata M, Nagai A, Matsuda K, Kamatani Y, Muto K, Kiyohara Y, Yamagata Z, Ninomiya T, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group. Erratum to "Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project" [J Epidemiol 27(3S) (2017) S36-S42]. J Epidemiol. 2017 08; 27(8):398-399.
PMID:
28592364
; PMCID:
PMC5549245
.
Citations:
Fields:
Epi
Epidemiology
Shindo Y, Hazama S,
Nakamura Y
, Inoue Y, Kanekiyo S, Suzuki N, Takenouchi H, Tsunedomi R, Nakajima M, Ueno T, Takeda S, Yoshino S, Okuno K, Fujita Y, Hamamoto Y, Kawakami Y, Oka M, Nagano H. miR-196b, miR-378a and miR-486 are predictive biomarkers for the efficacy of vaccine treatment in colorectal cancer. Oncol Lett. 2017 Aug; 14(2):1355-1362.
PMID:
28789351
; PMCID:
PMC5529876
.
Citations:
14
Wang R, Deng X, Yoshioka Y, Vougiouklakis T, Park JH, Suzuki T, Dohmae N, Ueda K, Hamamoto R,
Nakamura Y
. Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells. Cancer Sci. 2017 Jun; 108(6):1203-1209.
PMID:
28370702
; PMCID:
PMC5480063
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Tanikawa C, Zhang YZ, Yamamoto R, Tsuda Y, Tanaka M, Funauchi Y, Mori J, Imoto S, Yamaguchi R,
Nakamura Y
, Miyano S, Nakagawa H, Matsuda K. The Transcriptional Landscape of p53 Signalling Pathway. EBioMedicine. 2017 Jun; 20:109-119.
PMID:
28558959
; PMCID:
PMC5478243
.
Citations:
39
Fields:
Gen
Genetics
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Kato T, Iwasaki T, Uemura M, Nagahara A, Higashihara H, Osuga K, Ikeda Y, Kiyotani K, Park JH, Nonomura N,
Nakamura Y
. Characterization of the cryoablation-induced immune response in kidney cancer patients. Oncoimmunology. 2017; 6(7):e1326441.
PMID:
28811963
; PMCID:
PMC5543848
.
Citations:
27
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Oba U, Yamada H, Suenobu SI,
Nakamura Y
, Ito A, Hatano Y, Itonaga N, Ohshima K, Koga Y, Ohga S, Ihara K. Toxic epidermal necrolysis in a child 6 months post-hematopoietic stem cell transplantation. Pediatr Transplant. 2017 Aug; 21(5).
PMID:
28497658
.
Citations:
Fields:
Ped
Pediatrics
Tra
Transplantation
Translation:
Humans
Mai T, Takano A, Suzuki H, Hirose T, Mori T, Teramoto K, Kiyotani K,
Nakamura Y
, Daigo Y. Quantitative analysis and clonal characterization of T-cell receptor ß repertoires in patients with advanced non-small cell lung cancer treated with cancer vaccine. Oncol Lett. 2017 Jul; 14(1):283-292.
PMID:
28693166
; PMCID:
PMC5494838
.
Citations:
4
Telomeres Mendelian Randomization Collaboration, Haycock PC, Burgess S, Nounu A, Zheng J, Okoli GN, Bowden J, Wade KH, Timpson NJ, Evans DM, Willeit P, Aviv A, Gaunt TR, Hemani G, Mangino M, Ellis HP, Kurian KM, Pooley KA, Eeles RA, Lee JE, Fang S, Chen WV, Law MH, Bowdler LM, Iles MM, Yang Q, Worrall BB, Markus HS, Hung RJ, Amos CI, Spurdle AB, Thompson DJ, O'Mara TA, Wolpin B, Amundadottir L, Stolzenberg-Solomon R, Trichopoulou A, Onland-Moret NC, Lund E, Duell EJ, Canzian F, Overvad K, Gunter MJ, Tumino R, Svenson U, van Rij A, Baas AF, Bown MJ, Samani NJ, van t'Hof FNG, Tromp G, Jones GT, Kuivaniemi H, Elmore JR, Johansson M, Mckay J, Scelo G, Carreras-Torres R, Gaborieau V, Brennan P, Bracci PM, Neale RE, Olson SH, Gallinger S, Li D, Petersen GM, Risch HA, Klein AP, Han J, Abnet CC, Freedman ND, Taylor PR, Maris JM, Aben KK, Kiemeney LA, Vermeulen SH, Wiencke JK, Walsh KM, Wrensch M, Rice T, Turnbull C, Litchfield K, Paternoster L, SanGiovanni JP, Li Y, Mijatovic V, Sapkota Y, Low SK, Zondervan KT, Montgomery GW, Nyholt DR, van Heel DA, Hunt K, Arking DE, Ashar FN, Sotoodehnia N, Woo D, Rosand J, Comeau ME, Brown WM, Silverman EK, Hokanson JE, Cho MH, Hui J, Ferreira MA, Thompson PJ, Morrison AC, Felix JF, Smith NL, Christiano AM, Petukhova L, Betz RC, Fan X, Zhang X, Zhu C, Langefeld CD, Thompson SD, Wang F, Lin X, Schwartz DA, Fingerlin T, Rotter JI, Cotch MF, Jensen RA, Han F, Ollila HM, Hillary RP, Albagha O, Ralston SH, Zeng C, Zheng W, Shu XO, Kawamura Y, Otowa T, Sasaki T, Hibberd ML, Davila S, Xie G, Siminovitch K, Bei JX, Zeng YX, Chen B, Landi S, Franke A, Fischer A, Ellinghaus D, Flores C, Noth I, Ma SF, Foo JN, Liu J, Kim JW, Cox DG, Delattre O, Mirabeau O, Skibola CF, Tang CS, Garcia-Barcelo M, Chang KP, Su WH, Chang YS, Martin NG, Gordon S, Wade TD, Lee C, Kubo M, Cha PC,
Nakamura Y
, Levy D, Kimura M, Hwang SJ, Hunt S, Spector T, Soranzo N, Manichaikul AW, Barr RG, Kahali B, Speliotes E, Yerges-Armstrong LM, Cheng CY, Jonas JB, Wong TY, Fogh I, Lin K, Powell JF, Rice K, Relton CL, Martin RM, Davey Smith G, Severi G, Standl M, Abecasis GR, Munz M, Dommisch H, Schaefer AS, Reis A, Uebe S, Hüffmeier U, Försti A. Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. JAMA Oncol. 2017 May 01; 3(5):636-651.
PMID:
28241208
; PMCID:
PMC5638008
.
Citations:
265
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Saloura V, Fatima A, Zewde M, Kiyotani K, Brisson R, Park JH, Ikeda Y, Vougiouklakis T, Bao R, Khattri A, Seiwert T,
Cipriani N
,
Lingen M
,
Vokes E
,
Nakamura Y
. Characterization of the T-Cell Receptor Repertoire and Immune Microenvironment in Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck. Clin Cancer Res. 2017 Aug 15; 23(16):4897-4907.
PMID:
28442504
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Dudenkov TM, Ingle JN, Buzdar AU, Robson ME, Kubo M, Ibrahim-Zada I, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Barman P, Goetz MP, Northfelt DW, Moreno-Aspita A, Williard CV, Kalari KR,
Nakamura Y
, Wang L, Weinshilboum RM. SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. Breast Cancer Res Treat. 2017 Jul; 164(1):189-199.
PMID:
28429243
; PMCID:
PMC5600471
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Fujiwara Y, Okada K, Omori T, Sugimura K, Miyata H, Ohue M, Kobayashi S, Takahashi H, Nakano H, Mochizuki C, Shimizu K, Yano M,
Nakamura Y
, Mori M, Doki Y. Multiple therapeutic peptide vaccines for patients with advanced gastric cancer. Int J Oncol. 2017 May; 50(5):1655-1662.
PMID:
28393243
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Ikeda Y, Kiyotani K, Yew PY, Sato S, Imai Y, Yamaguchi R, Miyano S, Fujiwara K, Hasegawa K,
Nakamura Y
. Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer. Oncol Rep. 2017 May; 37(5):2603-2610.
PMID:
28358435
; PMCID:
PMC5428285
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Chiyoda T, Hart PC, Eckert MA, McGregor SM,
Lastra RR
, Hamamoto R,
Nakamura Y
,
Yamada SD
,
Olopade OI
,
Lengyel E
,
Romero IL
. Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention. Cancer Prev Res (Phila). 2017 Apr; 10(4):255-266.
PMID:
28264838
; PMCID:
PMC5425093
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Nakamura Y
, Takeichi H, Yamada S, Iwazaki M. Tracheal Bronchus: Beware of Anomalous Venous Drainage! Ann Thorac Surg. 2017 Mar; 103(3):e285.
PMID:
28219571
.
Citations:
Fields:
Gen
General Surgery
Pul
Pulmonary Medicine
Translation:
Humans
Park JH, Inoue H, Kato T, Zewde M, Miyamoto T, Matsuo Y,
Salgia R
,
Nakamura Y
. TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer. Cancer Sci. 2017 Mar; 108(3):488-496.
PMID:
28075524
; PMCID:
PMC5378278
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Shindo Y, Hazama S, Suzuki N, Iguchi H, Uesugi K, Tanaka H, Aruga A, Hatori T, Ishizaki H, Umeda Y, Fujiwara T, Ikemoto T, Shimada M, Yoshimatsu K, Takenouchi H, Matsui H, Kanekiyo S, Iida M, Koki Y, Arima H, Furukawa H, Ueno T, Yoshino S, Fujita T, Kawakami Y,
Nakamura Y
, Oka M, Nagano H. Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer. J Exp Clin Cancer Res. 2017 02 28; 36(1):36.
PMID:
28241889
; PMCID:
PMC5329922
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Nakamura K, Okada E, Ukawa S, Hirata M, Nagai A, Yamagata Z, Kiyohara Y, Muto K, Kamatani Y, Ninomiya T, Matsuda K, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Tamakoshi A. Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project. J Epidemiol. 2017 Mar; 27(3S):S58-S64.
PMID:
28223083
; PMCID:
PMC5350586
.
Citations:
19
Fields:
Epi
Epidemiology
Translation:
Humans
Ukawa S, Nakamura K, Okada E, Hirata M, Nagai A, Yamagata Z, Muto K, Matsuda K, Ninomiya T, Kiyohara Y, Kamatani Y, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Tamakoshi A. Clinical and histopathological characteristics of patients with prostate cancer in the BioBank Japan project. J Epidemiol. 2017 Mar; 27(3S):S65-S70.
PMID:
28215481
; PMCID:
PMC5350593
.
Citations:
5
Fields:
Epi
Epidemiology
Translation:
Humans
Ukawa S, Okada E, Nakamura K, Hirata M, Nagai A, Matsuda K, Yamagata Z, Kamatani Y, Ninomiya T, Kiyohara Y, Muto K, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Tamakoshi A. Characteristics of patients with liver cancer in the BioBank Japan project. J Epidemiol. 2017 Mar; 27(3S):S43-S48.
PMID:
28214185
; PMCID:
PMC5350594
.
Citations:
11
Fields:
Epi
Epidemiology
Translation:
Humans
Tamakoshi A, Nakamura K, Ukawa S, Okada E, Hirata M, Nagai A, Matsuda K, Kamatani Y, Muto K, Kiyohara Y, Yamagata Z, Ninomiya T, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group. Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project. J Epidemiol. 2017 Mar; 27(3S):S36-S42.
PMID:
28214186
; PMCID:
PMC5350596
.
Citations:
27
Fields:
Epi
Epidemiology
Translation:
Humans
Nakamura K, Ukawa S, Okada E, Hirata M, Nagai A, Yamagata Z, Ninomiya T, Muto K, Kiyohara Y, Matsuda K, Kamatani Y, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Tamakoshi A. Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project. J Epidemiol. 2017 Mar; 27(3S):S49-S57.
PMID:
28202209
; PMCID:
PMC5350589
.
Citations:
9
Fields:
Epi
Epidemiology
Translation:
Humans
Yokomichi H, Nagai A, Hirata M, Tamakoshi A, Kiyohara Y, Kamatani Y, Muto K, Ninomiya T, Matsuda K, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Yamagata Z. Statin use and all-cause and cancer mortality: BioBank Japan cohort. J Epidemiol. 2017 Mar; 27(3S):S84-S91.
PMID:
28196737
; PMCID:
PMC5350595
.
Citations:
20
Fields:
Epi
Epidemiology
Translation:
Humans
Yokomichi H, Noda H, Nagai A, Hirata M, Tamakoshi A, Kamatani Y, Kiyohara Y, Matsuda K, Muto K, Ninomiya T, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Yamagata Z. Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan. J Epidemiol. 2017 Mar; 27(3S):S77-S83.
PMID:
28196738
; PMCID:
PMC5350591
.
Citations:
3
Fields:
Epi
Epidemiology
Translation:
Humans
Yokomichi H, Nagai A, Hirata M, Kiyohara Y, Muto K, Ninomiya T, Matsuda K, Kamatani Y, Tamakoshi A, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Yamagata Z. Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort. J Epidemiol. 2017 Mar; 27(3S):S98-S106.
PMID:
28209242
; PMCID:
PMC5350597
.
Citations:
14
Fields:
Epi
Epidemiology
Translation:
Humans
Hirata M, Nagai A, Kamatani Y, Ninomiya T, Tamakoshi A, Yamagata Z, Kubo M, Muto K, Kiyohara Y, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Matsuda K. Overview of BioBank Japan follow-up data in 32 diseases. J Epidemiol. 2017 Mar; 27(3S):S22-S28.
PMID:
28190660
; PMCID:
PMC5363789
.
Citations:
29
Fields:
Epi
Epidemiology
Translation:
Humans
Hirata M, Kamatani Y, Nagai A, Kiyohara Y, Ninomiya T, Tamakoshi A, Yamagata Z, Kubo M, Muto K, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Matsuda K. Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases. J Epidemiol. 2017 Mar; 27(3S):S9-S21.
PMID:
28190657
; PMCID:
PMC5363792
.
Citations:
80
Fields:
Epi
Epidemiology
Translation:
Humans
Okada E, Ukawa S, Nakamura K, Hirata M, Nagai A, Matsuda K, Ninomiya T, Kiyohara Y, Muto K, Kamatani Y, Yamagata Z, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Tamakoshi A. Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project. J Epidemiol. 2017 Mar; 27(3S):S29-S35.
PMID:
28190659
; PMCID:
PMC5350592
.
Citations:
18
Fields:
Epi
Epidemiology
Translation:
Humans
Nagai A, Hirata M, Kamatani Y, Muto K, Matsuda K, Kiyohara Y, Ninomiya T, Tamakoshi A, Yamagata Z, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Kubo M. Overview of the BioBank Japan Project: Study design and profile. J Epidemiol. 2017 Mar; 27(3S):S2-S8.
PMID:
28189464
; PMCID:
PMC5350590
.
Citations:
280
Fields:
Epi
Epidemiology
Translation:
Humans
Yokomichi H, Nagai A, Hirata M, Kiyohara Y, Muto K, Ninomiya T, Matsuda K, Kamatani Y, Tamakoshi A, Kubo M,
Nakamura Y
, BioBank Japan Cooperative Hospital Group, Yamagata Z. Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan. J Epidemiol. 2017 Mar; 27(3S):S92-S97.
PMID:
28162891
; PMCID:
PMC5350587
.
Citations:
8
Fields:
Epi
Epidemiology
Translation:
Humans
Saloura V, Vougiouklakis T, Zewde M, Deng X, Kiyotani K, Park JH, Matsuo Y,
Lingen M
, Suzuki T, Dohmae N, Hamamoto R,
Nakamura Y
. WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer. Sci Rep. 2017 01 19; 7:40664.
PMID:
28102297
; PMCID:
PMC5244396
.
Citations:
26
Fields:
Sci
Science
Translation:
Humans
Cells
Kiyotani K, Park JH, Inoue H,
Husain A
, Olugbile S, Zewde M,
Nakamura Y
, Vigneswaran WT. Integrated analysis of somatic mutations and immune microenvironment in malignant pleural mesothelioma. Oncoimmunology. 2017; 6(2):e1278330.
PMID:
28344893
; PMCID:
PMC5353938
.
Citations:
36
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Lin J, Chung S, Ueda K, Matsuda K,
Nakamura Y
, Park JH. GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition. Neoplasia. 2017 01; 19(1):43-53.
PMID:
28110670
; PMCID:
PMC6197318
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hata J, Nagai A, Hirata M, Kamatani Y, Tamakoshi A, Yamagata Z, Muto K, Matsuda K, Kubo M,
Nakamura Y
, Biobank Japan Cooperative Hospital Group, Kiyohara Y, Ninomiya T. Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project. J Epidemiol. 2017 Mar; 27(3S):S71-S76.
PMID:
28142037
; PMCID:
PMC5350588
.
Citations:
5
Fields:
Epi
Epidemiology
Translation:
Humans
Suzuki N, Hazama S, Iguchi H, Uesugi K, Tanaka H, Hirakawa K, Aruga A, Hatori T, Ishizaki H, Umeda Y, Fujiwara T, Ikemoto T, Shimada M, Yoshimatsu K, Shimizu R, Hayashi H, Sakata K, Takenouchi H, Matsui H, Shindo Y, Iida M, Koki Y, Arima H, Furukawa H, Ueno T, Yoshino S,
Nakamura Y
, Oka M, Nagano H. Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study. Cancer Sci. 2017 Jan; 108(1):73-80.
PMID:
27783849
; PMCID:
PMC5276830
.
Citations:
34
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Suga A, Yamada S, Takeichi H,
Nakamura Y
, Iwazaki M. L-shaped mini-sternotomy combined with videoscopic approach for thymoma with invasion of major veins. J Surg Case Rep. 2016 Dec 01; 2016(11).
PMID:
27908939
; PMCID:
PMC5619589
.
Citations:
Kiyotani K, Mai TH,
Nakamura Y
. Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors. J Hum Genet. 2017 Mar; 62(3):397-405.
PMID:
27881843
; PMCID:
PMC5334549
.
Citations:
29
Fields:
Gen
Genetics
Translation:
Humans
Alachkar H, Mutonga M, Kato T, Kalluri S, Kakuta Y, Uemura M, Imamura R, Nonomura N, Vujjini V, Alasfar S, Rabb H,
Nakamura Y
, Alachkar N. Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection. BMC Nephrol. 2016 11 21; 17(1):181.
PMID:
27871261
; PMCID:
PMC5117555
.
Citations:
19
Fields:
Nep
Nephrology
Translation:
Humans
Cells
Yap KL, Furtado LV, Kiyotani K, Curran E,
Stock W
,
McNeer JL
, Kadri S,
Segal JP
,
Nakamura Y
, Le Beau MM,
Gurbuxani S
, Raca G. Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL). Leuk Lymphoma. 2017 04; 58(4):950-958.
PMID:
27855558
; PMCID:
PMC6077981
.
Citations:
10
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Yoshioka Y, Suzuki T, Matsuo Y, Nakakido M, Tsurita G, Simone C, Watanabe T, Dohmae N,
Nakamura Y
, Hamamoto R. SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1. Oncotarget. 2016 Nov 15; 7(46):75023-75037.
PMID:
27626683
; PMCID:
PMC5342720
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Deng X,
Nakamura Y
. Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy. Trends Pharmacol Sci. 2017 01; 38(1):15-24.
PMID:
27842888
.
Citations:
34
Fields:
Pha
Pharmacology
Translation:
Humans
Park JH, Chung S, Matsuo Y,
Nakamura Y
. Development of small molecular compounds targeting cancer stem cells. Medchemcomm. 2017 Jan 01; 8(1):73-80.
PMID:
30108692
; PMCID:
PMC6072478
.
Citations:
9
Olugbile S, Kiyotani K, Park JH,
Hoffman P
, Szeto L, Patel J,
Vokes E
,
Nakamura Y
. PS01.05: Early and Persistent Oligoclonal T Cell Expansion Correlates with Durable Response to Anti-PD1 Therapy in NSCLC: Topic: Medical Oncology. J Thorac Oncol. 2016 Nov; 11(11S):S272.
PMID:
27969473
.
Citations:
Uno Y, Takata R, Kito G, Yamazaki H, Nakagawa K,
Nakamura Y
, Kamataki T, Katagiri T. Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes. Drug Metab Pharmacokinet. 2017 Feb; 32(1):100-107.
PMID:
28153492
.
Citations:
8
Fields:
Met
Metabolism
Pha
Pharmacology
Translation:
Humans
Zembutsu H, Nakamura S, Akashi-Tanaka S, Kuwayama T, Watanabe C, Takamaru T, Takei H, Ishikawa T, Miyahara K, Matsumoto H, Hasegawa Y, Kutomi G, Shima H, Satomi F, Okazaki M, Zaha H, Onomura M, Matsukata A, Sagara Y, Baba S, Yamada A, Shimada K, Shimizu D, Tsugawa K, Shimo A, Tan EY, Hartman M, Chan CW, Lee SC,
Nakamura Y
. Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study. Clin Cancer Res. 2017 04 15; 23(8):2019-2026.
PMID:
27797974
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Obara W, Karashima T, Takeda K, Kato R, Kato Y, Kanehira M, Takata R, Inoue K, Katagiri T, Shuin T,
Nakamura Y
, Fujioka T. Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma. Cancer Immunol Immunother. 2017 01; 66(1):17-24.
PMID:
27757561
; PMCID:
PMC5222936
.
Citations:
12
Fields:
All
Allergy and Immunology
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
CT
Clinical Trials
Stefka AT, Park JH, Matsuo Y, Chung S,
Nakamura Y
,
Jakubowiak AJ
, Rosebeck S. Anti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells. Blood Cancer J. 2016 08 19; 6(8):e460.
PMID:
27540718
; PMCID:
PMC5022182
.
Citations:
11
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Shiraishi K, Okada Y, Takahashi A, Kamatani Y, Momozawa Y, Ashikawa K, Kunitoh H, Matsumoto S, Takano A, Shimizu K, Goto A, Tsuta K, Watanabe SI, Ohe Y, Watanabe Y, Goto Y, Nokihara H, Furuta K, Yoshida A, Goto K, Hishida T, Tsuboi M, Tsuchihara K, Miyagi Y, Nakayama H, Yokose T, Tanaka K, Nagashima T, Ohtaki Y, Maeda D, Imai K, Minamiya Y, Sakamoto H, Saito A, Shimada Y, Sunami K, Saito M, Inazawa J,
Nakamura Y
, Yoshida T, Yokota J, Matsuda F, Matsuo K, Daigo Y, Kubo M, Kohno T. Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma. Nat Commun. 2016 08 09; 7:12451.
PMID:
27501781
; PMCID:
PMC4980483
.
Citations:
33
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Nakamura T, Katagiri T, Sato S, Kushibiki T, Hontani K, Tsuchikawa T, Hirano S,
Nakamura Y
. Overexpression of C16orf74 is involved in aggressive pancreatic cancers. Oncotarget. 2016 Jul 28.
PMID:
27486884
.
Citations:
Nakamura T, Katagiri T, Sato S, Kushibiki T, Hontani K, Tsuchikawa T, Hirano S,
Nakamura Y
. Overexpression of C16orf74 is involved in aggressive pancreatic cancers. Oncotarget. 2017 Aug 01; 8(31):50460-50475.
PMID:
28881575
; PMCID:
PMC5584151
.
Citations:
7
Fields:
Neo
Neoplasms
van 't Hof FN, Ruigrok YM, Lee CH, Anderson G, de Andrade M, Baas AF, Blankensteijn JD, Bown MJ, Broderick J, Carrell DS, Crawford DC, Crosslin DR, Ebeling C, Fornage M, Foroud T, von Und Zu Fraunberg M, Friedrich CM, Gottesman O, Guo DC, Harrison SC, Hernesniemi J, Hofman A, Inoue I, Jones GT, Kiemeney LA, Kivisaari R, Ko N, Koskinen S, Kubo M, Kullo IJ, Kuivaniemi H, Kurki MI, Laakso A, Lai D, Leal SM, Lehto H, LeMaire SA, Low SK, Malinowski J, McCarty CA, Milewicz DM, Mosley TH, Nakaoka H, Pacheco J, Peissig PL, Pera J, Rasmussen-Torvik L, Ritchie MD, Rivadeneira F, van Rij AM, Santos-Cortez RL, Saratzis A, Slowik A, Takahashi A, Tromp G, Verma SS, Vermeulen SH, Wang GT, Aneurysm Consortium; Vascular Research Consortium of New Zealand, Han B, de Bakker PI, Ripke S, Böttinger EP, Bijlenga P, Eriksson JG, Gaál EI, Jääskeläinen JE,
Nakamura Y
, Niemelä M, Uitterlinden AG, Rinkel GJ. Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms. J Am Heart Assoc. 2016 07 14; 5(7).
PMID:
27418160
; PMCID:
PMC5015357
.
Citations:
29
Fields:
Car
Cardiology
Vas
Vascular Diseases
Translation:
Humans
Nakakido M, Tamura K, Chung S, Ueda K, Fujii R, Kiyotani K,
Nakamura Y
. Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors. Int J Oncol. 2016 Sep; 49(3):868-76.
PMID:
27572108
; PMCID:
PMC4948962
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Saloura V, Vougiouklakis T, Zewde M, Kiyotani K, Park JH,
Gao G
,
Karrison T
,
Lingen M
,
Nakamura Y
, Hamamoto R. WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck. Oncotarget. 2016 Jul 05; 7(27):42527-42538.
PMID:
27285764
; PMCID:
PMC5173153
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kimura T, Fukushima S, Miyashita A, Aoi J, Jinnin M, Kosaka T, Ando Y, Matsukawa M, Ihn H, Inoue H, Kiyotani K, Park JH,
Nakamura Y
. Myasthenic crisis and polymyositis induced by one dose of nivolumab. Cancer Sci. 2016 Jul; 107(7):1055-8.
PMID:
27420474
; PMCID:
PMC4946722
.
Citations:
72
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Inoue H, Park JH, Kiyotani K, Zewde M, Miyashita A, Jinnin M, Kiniwa Y, Okuyama R, Tanaka R, Fujisawa Y, Kato H, Morita A, Asai J, Katoh N, Yokota K, Akiyama M, Ihn H, Fukushima S,
Nakamura Y
. Intratumoral expression levels of PD-L1, GZMA, and HLA-A along with oligoclonal T cell expansion associate with response to nivolumab in metastatic melanoma. Oncoimmunology. 2016; 5(9):e1204507.
PMID:
27757299
; PMCID:
PMC5048759
.
Citations:
70
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Chin YM, Tan LP, Abdul Aziz N, Mushiroda T, Kubo M, Mohd Kornain NK, Tan GW, Khoo AS, Krishnan G, Pua KC, Yap YY, Teo SH, Lim PV,
Nakamura Y
, Lum CL, Malaysian NPC Study Group, Ng CC. Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort. Int J Cancer. 2016 10 15; 139(8):1731-9.
PMID:
27236004
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ikeda Y, Park JH, Miyamoto T, Takamatsu N, Kato T, Iwasa A, Okabe S, Imai Y, Fujiwara K,
Nakamura Y
, Hasegawa K. T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer. Clin Cancer Res. 2016 Dec 15; 22(24):6110-6117.
PMID:
27334838
.
Citations:
49
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Yamaguchi R, Tamura K, Weidner J, Imoto S, Kwon J,
Fang H
, Yew PY, Marino SR, Miyano S,
Nakamura Y
, Kiyotani K, Chapman CG. Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing. Inflamm Bowel Dis. 2016 06; 22(6):1275-85.
PMID:
27135481
.
Citations:
22
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Park JH, Jang M, Tarhan YE, Katagiri T, Sasa M, Miyoshi Y, Kalari KR, Suman VJ, Weinshilboum R, Wang L, Boughey JC, Goetz MP,
Nakamura Y
. Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy. Int J Oncol. 2016 Aug; 49(2):471-8.
PMID:
27278091
; PMCID:
PMC4922832
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hertz DL, Owzar K, Lessans S, Wing C, Jiang C, Kelly WK, Patel J, Halabi S, Furukawa Y, Wheeler HE, Sibley AB, Lassiter C, Weisman L, Watson D, Krens SD, Mulkey F, Renn CL, Small EJ, Febbo PG, Shterev I, Kroetz DL, Friedman PN, Mahoney JF, Carducci MA, Kelley MJ,
Nakamura Y
, Kubo M, Dorsey SG,
Dolan ME
, Morris MJ,
Ratain MJ
, McLeod HL. Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy. Clin Cancer Res. 2016 Oct 01; 22(19):4890-4900.
PMID:
27143689
; PMCID:
PMC5050068
.
Citations:
33
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
CT
Clinical Trials
Piao L, Nakakido M, Suzuki T, Dohmae N,
Nakamura Y
, Hamamoto R. Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins. Oncotarget. 2016 Apr 19; 7(16):22846-56.
PMID:
26988914
; PMCID:
PMC5008405
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Tamura K, Hazama S, Yamaguchi R, Imoto S, Takenouchi H, Inoue Y, Kanekiyo S, Shindo Y, Miyano S,
Nakamura Y
, Kiyotani K. Characterization of the T cell repertoire by deep T cell receptor sequencing in tissues and blood from patients with advanced colorectal cancer. Oncol Lett. 2016 Jun; 11(6):3643-3649.
PMID:
27284367
; PMCID:
PMC4887943
.
Citations:
22
Tarhan YE, Kato T, Jang M, Haga Y, Ueda K,
Nakamura Y
, Park JH. Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown. Neoplasia. 2016 05; 18(5):265-272.
PMID:
27237318
; PMCID:
PMC4887616
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Murahashi M, Hijikata Y, Yamada K, Tanaka Y, Kishimoto J, Inoue H, Marumoto T, Takahashi A, Okazaki T, Takeda K, Hirakawa M, Fujii H, Okano S, Morita M, Baba E, Mizumoto K, Maehara Y, Tanaka M, Akashi K, Nakanishi Y, Yoshida K, Tsunoda T, Tamura K,
Nakamura Y
, Tani K. Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors. Clin Immunol. 2016 05; 166-167:48-58.
PMID:
27072896
.
Citations:
29
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
CT
Clinical Trials
Chung S, Kijima K, Kudo A, Fujisawa Y, Harada Y, Taira A, Takamatsu N, Miyamoto T, Matsuo Y,
Nakamura Y
. Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor. Oncotarget. 2016 Apr 05; 7(14):18171-82.
PMID:
26918358
; PMCID:
PMC4951280
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Kato T, Inoue H, Imoto S, Tamada Y, Miyamoto T, Matsuo Y,
Nakamura Y
, Park JH. Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells. Oncotarget. 2016 Apr 05; 7(14):17652-64.
PMID:
26933922
; PMCID:
PMC4951240
.
Citations:
30
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Choudhury NJ
, Campanile A,
Antic T
, Yap KL,
Fitzpatrick CA
, Wade JL,
Karrison T
,
Stadler WM
,
Nakamura Y
,
O'Donnell PH
. Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations. J Clin Oncol. 2016 06 20; 34(18):2165-71.
PMID:
27044931
; PMCID:
PMC5569685
.
Citations:
82
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Inoue H, Kato T, Olugbile S, Tamura K, Chung S, Miyamoto T, Matsuo Y,
Salgia R
,
Nakamura Y
, Park JH. Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer. Oncotarget. 2016 Mar 22; 7(12):13621-33.
PMID:
26871945
; PMCID:
PMC4924666
.
Citations:
29
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Shiobara T, Chibana K, Watanabe T, Arai R, Horigane Y,
Nakamura Y
, Hayashi Y, Shimizu Y, Takemasa A, Ishii Y. Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells. Respir Res. 2016 Mar 14; 17:28.
PMID:
26975422
; PMCID:
PMC4791890
.
Citations:
35
Fields:
Pul
Pulmonary Medicine
Translation:
Humans
Cells
Mori J, Tanikawa C, Funauchi Y, Lo PH,
Nakamura Y
, Matsuda K. Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity. Cancer Sci. 2016 Mar; 107(3):298-306.
PMID:
26757339
; PMCID:
PMC4814261
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hamamoto R,
Nakamura Y
. Dysregulation of protein methyltransferases in human cancer: An emerging target class for anticancer therapy. Cancer Sci. 2016 Apr; 107(4):377-84.
PMID:
26751963
; PMCID:
PMC4832871
.
Citations:
36
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Choudhury N
,
Nakamura Y
. Importance of immunopharmacogenomics in cancer treatment: Patient selection and monitoring for immune checkpoint antibodies. Cancer Sci. 2016 Feb; 107(2):107-15.
PMID:
26678880
; PMCID:
PMC4768396
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Nakamura Y
, Ishikawa K, Kai Y, Shimada H, Kawano M, Iwasaki T, Tagomori H, Tanata K, Tsumura H, Arakane M, Nishida H, Yokoyama S, Hatano Y, Fujiwara S. Case of malignant melanoma that developed the ability to secrete granulocyte colony-stimulating factor. J Dermatol. 2016 May; 43(5):580-2.
PMID:
26777544
.
Citations:
2
Fields:
Der
Dermatology
Translation:
Humans
Ikeda Y, Kiyotani K, Yew PY, Kato T, Tamura K, Yap KL, Nielsen SM, Mester JL, Eng C,
Nakamura Y
, Grogan RH. Germline PARP4 mutations in patients with primary thyroid and breast cancers. Endocr Relat Cancer. 2016 Mar; 23(3):171-9.
PMID:
26699384
; PMCID:
PMC5152685
.
Citations:
32
Fields:
End
Endocrinology
Neo
Neoplasms
Translation:
Humans
Cells
Vougiouklakis T, Sone K, Saloura V, Cho HS, Suzuki T, Dohmae N, Alachkar H,
Nakamura Y
, Hamamoto R. SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells. Oncotarget. 2015 Dec 22; 6(41):43162-71.
PMID:
26586479
; PMCID:
PMC4791223
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Engels B, Schreiber K, Yew PY, Kiyotani K, Idel C,
Arina A
, Duraiswamy J,
Weichselbaum RR
,
Nakamura Y
, Leisegang M, Uckert W,
Schreiber H
. Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation. Clin Cancer Res. 2016 06 01; 22(11):2734-43.
PMID:
26667491
; PMCID:
PMC4891260
.
Citations:
42
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Nakamura Y
. The current and future applications of immunopharmacogenomics. Clin Adv Hematol Oncol. 2015 Dec; 13(12):815-7.
PMID:
27058847
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Funauchi Y, Tanikawa C, Yi Lo PH, Mori J, Daigo Y, Takano A, Miyagi Y, Okawa A,
Nakamura Y
, Matsuda K. Regulation of iron homeostasis by the p53-ISCU pathway. Sci Rep. 2015 Nov 12; 5:16497.
PMID:
26560363
; PMCID:
PMC4642350
.
Citations:
51
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Deng X, Von Keudell G, Suzuki T, Dohmae N, Nakakido M, Piao L, Yoshioka Y,
Nakamura Y
, Hamamoto R. PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP. Oncotarget. 2015 Nov 03; 6(34):35173-82.
PMID:
26460953
; PMCID:
PMC4742097
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Alachkar H, Mutonga M, Malnassy G, Park JH, Fulton N, Woods A, Meng L,
Kline J
, Raca G,
Odenike O
, Takamatsu N, Miyamoto T, Matsuo Y,
Stock W
,
Nakamura Y
. T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia. Oncotarget. 2015 Oct 20; 6(32):33410-25.
PMID:
26450903
; PMCID:
PMC4741775
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Nakakido M, Deng Z, Suzuki T, Dohmae N,
Nakamura Y
, Hamamoto R. PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents. Oncotarget. 2015 Oct 13; 6(31):30957-67.
PMID:
26436589
; PMCID:
PMC4741580
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Choudhury NJ
, Kiyotani K, Yap KL, Campanile A,
Antic T
, Yew PY, Steinberg G, Park JH,
Nakamura Y
,
O'Donnell PH
. Low T-cell Receptor Diversity, High Somatic Mutation Burden, and High Neoantigen Load as Predictors of Clinical Outcome in Muscle-invasive Bladder Cancer. Eur Urol Focus. 2016 Oct; 2(4):445-452.
PMID:
28723478
.
Citations:
44
Fields:
Uro
Urology
Mutonga M, Tamura K, Malnassy G, Fulton N, de Albuquerque A, Hamamoto R,
Stock W
,
Nakamura Y
, Alachkar H. Targeting Suppressor of Variegation 3-9 Homologue 2 (SUV39H2) in Acute Lymphoblastic Leukemia (ALL). Transl Oncol. 2015 Oct; 8(5):368-375.
PMID:
26500027
; PMCID:
PMC4631083
.
Citations:
14
Piao L, Suzuki T, Dohmae N,
Nakamura Y
, Hamamoto R. SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells. Oncotarget. 2015 Jul 10; 6(19):16939-50.
PMID:
26183527
; PMCID:
PMC4627283
.
Citations:
34
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Alachkar H,
Nakamura Y
. Deep-sequencing of the T-cell receptor repertoire in patients with haplo-cord and matched-donor transplants. Chimerism. 2015 Jul 03; 6(3):47-9.
PMID:
26745665
; PMCID:
PMC5154355
.
Citations:
5
Fields:
Mol
Molecular Biology
Tra
Transplantation
Translation:
Humans
Yew PY, Alachkar H, Yamaguchi R, Kiyotani K,
Fang H
, Yap KL,
Liu HT
,
Wickrema A
, Artz A,
van Besien K
, Imoto S, Miyano S,
Bishop MR
,
Stock W
,
Nakamura Y
. Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients. Bone Marrow Transplant. 2015 Sep; 50(9):1227-34.
PMID:
26052909
; PMCID:
PMC4559843
.
Citations:
64
Fields:
Tra
Transplantation
Translation:
Humans
Cells
CT
Clinical Trials
Komatsu M, Wheeler HE, Chung S, Low SK, Wing C, Delaney SM, Gorsic LK, Takahashi A, Kubo M, Kroetz DL, Zhang W,
Nakamura Y
,
Dolan ME
. Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy. Clin Cancer Res. 2015 Oct 01; 21(19):4337-46.
PMID:
26015512
; PMCID:
PMC4592389
.
Citations:
27
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Vougiouklakis T, Hamamoto R,
Nakamura Y
, Saloura V. The NSD family of protein methyltransferases in human cancer. Epigenomics. 2015 Aug; 7(5):863-74.
PMID:
25942451
.
Citations:
49
Fields:
Gen
Genetics
Translation:
Humans
Cells
Jang M, Yew PY, Hasegawa K, Ikeda Y, Fujiwara K,
Fleming GF
,
Nakamura Y
, Park JH. Characterization of T cell repertoire of blood, tumor, and ascites in ovarian cancer patients using next generation sequencing. Oncoimmunology. 2015 Nov; 4(11):e1030561.
PMID:
26451311
; PMCID:
PMC4589054
.
Citations:
32
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Yoshitake Y, Nishimura Y,
Nakamura Y
, Shinohara M. A clinical trial of multiple peptides vaccination for advanced head and neck cancer patients induced immune responses and prolonged OS. Oncoimmunology. 2015 Aug; 4(8):e1022307.
PMID:
26405579
; PMCID:
PMC4570101
.
Citations:
5
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Nakakido M, Deng Z, Suzuki T, Dohmae N,
Nakamura Y
, Hamamoto R. Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN. Neoplasia. 2015 Apr; 17(4):367-73.
PMID:
25925379
; PMCID:
PMC4415136
.
Citations:
47
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kusakabe K, Ide N, Daigo Y, Itoh T, Yamamoto T, Kojima E, Mitsuoka Y, Tadano G, Tagashira S, Higashino K, Okano Y, Sato Y, Inoue M, Iguchi M, Kanazawa T, Ishioka Y, Dohi K, Kido Y, Sakamoto S, Ando S, Maeda M, Higaki M, Yoshizawa H, Murai H,
Nakamura Y
. A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity. Bioorg Med Chem. 2015 May 01; 23(9):2247-60.
PMID:
25801152
.
Citations:
6
Fields:
Bio
Biochemistry
Che
Chemistry
Translation:
Humans
Animals
Cells
Ide N, Daigo Y, Itoh T, Yamamoto T, Hashizume H, Nozu K, Yoshida H, Tadano G, Tagashira S, Higashino K, Okano Y, Sato Y, Inoue M, Iguchi M, Kanazawa T, Ishioka Y, Dohi K, Kido Y, Sakamoto S, Ando S, Maeda M, Higaki M, Baba Y,
Nakamura Y
, Kusakabe K. Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity. J Med Chem. 2015 Feb 26; 58(4):1760-75.
PMID:
25625617
.
Citations:
20
Fields:
Che
Chemistry
Translation:
Humans
Animals
Cells
Liu X,
Venkataraman G
, Lin J, Kiyotani K, Smith S, Montoya M,
Nakamura Y
,
Kline J
. Highly clonal regulatory T-cell population in follicular lymphoma - inverse correlation with the diversity of CD8+ T cells. Oncoimmunology. 2015 May; 4(5):e1002728.
PMID:
26155390
; PMCID:
PMC4485720
.
Citations:
13
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Hamamoto R, Saloura V,
Nakamura Y
. Critical roles of non-histone protein lysine methylation in human tumorigenesis. Nat Rev Cancer. 2015 Feb; 15(2):110-24.
PMID:
25614009
.
Citations:
171
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Tanakaya K, Furukawa Y,
Nakamura Y
, Hirata K, Tomita N, Tamura K, Sugano K, Ishioka C, Yoshida T, Ishida H, Watanabe T, Sugihara K, HNPCC registry and genetic testing project of the Japanese Society for Cancer of the Colon and Rectu, Yamaguchi T, Ishikawa H, Matsubara N, Arai M, Moriya Y. Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum. Jpn J Clin Oncol. 2015 Mar; 45(3):307-10.
PMID:
25583420
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Vachon CM, Schaid DJ, Ingle JN, Wickerham DL, Kubo M, Mushiroda T, Goetz MP, Carlson EE, Paik S, Wolmark N,
Nakamura Y
, Wang L, Weinshilboum R, Couch FJ. A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2. Breast Cancer Res Treat. 2015 Jan; 149(2):517-23.
PMID:
25575444
; PMCID:
PMC4327931
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Fang H
, Yamaguchi R, Liu X, Daigo Y, Yew PY, Tanikawa C, Matsuda K, Imoto S, Miyano S,
Nakamura Y
. Quantitative T cell repertoire analysis by deep cDNA sequencing of T cell receptor a and ß chains using next-generation sequencing (NGS). Oncoimmunology. 2014 Dec; 3(12):e968467.
PMID:
25964866
; PMCID:
PMC4368121
.
Citations:
47
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Alachkar H, Mutonga MB, Fulton N, Malnassy G, Bohlander SK, Matsuo Y,
Stock W
,
Nakamura Y
, Metzeler KH, Herold T, Spiekermann K, Hiddemann W. Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia. Oncotarget. 2014 Dec 15; 5(23):12371-82.
PMID:
25365263
; PMCID:
PMC4323011
.
Citations:
37
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Sone K, Piao L, Nakakido M, Ueda K,
Nakamura Y
, Hamamoto R, Jenuwein T. Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair. Nat Commun. 2014 Dec 09; 5:5691.
PMID:
25487737
; PMCID:
PMC4268694
.
Citations:
58
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Cells
Goetz MP, Sun JX, Suman VJ, Silva GO, Perou CM,
Nakamura Y
,
Cox NJ
, Stephens PJ, Miller VA, Ross JS, Chen D, Safgren SL, Kuffel MJ, Ames MM, Kalari KR, Gomez HL, Gonzalez-Angulo AM, Burgues O, Brauch HB, Ingle JN,
Ratain MJ
, Yelensky R. Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies. J Natl Cancer Inst. 2014 Dec 08; 107(2).
PMID:
25490892
; PMCID:
PMC4565524
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Yamaguchi T, Furukawa Y,
Nakamura Y
, Matsubara N, Ishikawa H, Arai M, Tomita N, Tamura K, Sugano K, Ishioka C, Yoshida T, Moriya Y, Ishida H, Watanabe T, Sugihara K, HNPCC Registry and Genetic Testing Project of the Japanese Society for Cancer of the Colon and Rectu. Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum. Jpn J Clin Oncol. 2015 Feb; 45(2):153-9.
PMID:
25404568
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Yoshitake Y, Fukuma D, Yuno A, Hirayama M, Nakayama H, Tanaka T, Nagata M, Takamune Y, Kawahara K, Nakagawa Y, Yoshida R, Hirosue A, Ogi H, Hiraki A, Jono H, Hamada A, Yoshida K, Nishimura Y,
Nakamura Y
, Shinohara M. Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS. Clin Cancer Res. 2015 Jan 15; 21(2):312-21.
PMID:
25391695
.
Citations:
74
Fields:
Neo
Neoplasms
Translation:
Humans
PH
Public Health
CT
Clinical Trials
Lo PH, Tanikawa C, Katagiri T,
Nakamura Y
, Matsuda K. Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma. Oncol Rep. 2015 Jan; 33(1):267-73.
PMID:
25370079
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Suga A, Yamada S, Takeichi H, Masuda D,
Nakamura Y
, Iwazaki M. Recurrence in regional pulmonary lymph nodes after surgery for isolated pulmonary metastasis from hepatocellular carcinoma. Gen Thorac Cardiovasc Surg. 2016 Jun; 64(6):351-4.
PMID:
25359152
.
Citations:
1
Fields:
Car
Cardiology
Gen
General Surgery
Pul
Pulmonary Medicine
Vas
Vascular Diseases
Translation:
Humans
Matsuo Y, Park JH, Miyamoto T, Yamamoto S, Hisada S, Alachkar H,
Nakamura Y
. TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis. Sci Transl Med. 2014 Oct 22; 6(259):259ra145.
PMID:
25338756
.
Citations:
65
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Yap KL, Kiyotani K, Tamura K,
Antic T
, Jang M, Montoya M, Campanile A, Yew PY, Ganshert C, Fujioka T, Steinberg GD,
O'Donnell PH
,
Nakamura Y
. Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival. Clin Cancer Res. 2014 Dec 15; 20(24):6605-17.
PMID:
25316812
; PMCID:
PMC4268280
.
Citations:
45
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Saloura V, Cho HS, Kiyotani K, Alachkar H, Zuo Z, Nakakido M, Tsunoda T, Seiwert T,
Lingen M
, Licht J,
Nakamura Y
, Hamamoto R. WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck. Mol Cancer Res. 2015 Feb; 13(2):293-304.
PMID:
25280969
.
Citations:
53
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Matsuda K, Takahashi A, Middlebrooks CD, Obara W, Nasu Y, Inoue K, Tamura K, Yamasaki I, Naya Y, Tanikawa C, Cui R, Figueroa JD, Silverman DT, Rothman N, Namiki M, Tomita Y, Nishiyama H, Kohri K, Deguchi T, Nakagawa M, Yokoyama M, Miki T, Kumon H, Fujioka T, Prokunina-Olsson L, Kubo M,
Nakamura Y
, Shuin T. Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population. Hum Mol Genet. 2015 Feb 15; 24(4):1177-84.
PMID:
25281661
; PMCID:
PMC4834880
.
Citations:
23
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Liu M, Goss PE, Ingle JN, Kubo M, Furukawa Y, Batzler A, Jenkins GD, Carlson EE,
Nakamura Y
, Schaid DJ, Chapman JA, Shepherd LE, Ellis MJ, Khosla S, Wang L, Weinshilboum RM. Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics. Mol Endocrinol. 2014 Oct; 28(10):1740-51.
PMID:
25148458
; PMCID:
PMC4179631
.
Citations:
24
Fields:
End
Endocrinology
Mol
Molecular Biology
Translation:
Humans
Keller MF, Reiner AP, Okada Y, van Rooij FJ, Johnson AD, Chen MH, Smith AV, Morris AP, Tanaka T, Ferrucci L, Zonderman AB, Harris T, Garcia M, Bandinelli S, Qayyum R, Yanek LR, Becker DM, Becker LC, Kooperberg C, Keating B, Reis J, Tang H, Boerwinkle E, Kamatani Y, Matsuda K, Kamatani N,
Nakamura Y
, Kubo M, Liu S, Dehghan A, Felix JF, Hofman A, van Duijn CM, Franco OH, Longo DL, Singleton AB, Psaty BM, Evans MK, Cupples LA, Rotter JI, O'Donnell CJ, Takahashi A, Wilson JG, Ganesh SK, Nalls MA, CHARGE Hematology, COGENT, BioBank Japan Project (RIKEN) Working Groups, Lettre G, Uitterlinden AG. Trans-ethnic meta-analysis of white blood cell phenotypes. Hum Mol Genet. 2014 Dec 20; 23(25):6944-60.
PMID:
25096241
; PMCID:
PMC4245044
.
Citations:
41
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Wolpin BM, Rizzato C, Kraft P, Kooperberg C, Petersen GM, Wang Z, Arslan AA, Beane-Freeman L, Bracci PM, Buring J, Canzian F, Duell EJ, Gallinger S, Giles GG, Goodman GE, Goodman PJ, Jacobs EJ, Kamineni A, Klein AP, Kolonel LN, Kulke MH, Li D, Olson SH, Risch HA, Sesso HD, Visvanathan K, White E, Zheng W, Abnet CC, Albanes D, Andreotti G, Austin MA, Barfield R, Basso D, Berndt SI, Boutron-Ruault MC, Brotzman M, Bueno-de-Mesquita HB, Burdette L, Campa D, Caporaso NE, Capurso G, Chung C, Cotterchio M, Costello E, Elena J, Funel N, Gaziano JM, Giese NA, Giovannucci EL, Goggins M, Gorman MJ, Gross M, Haiman CA, Hassan M, Helzlsouer KJ, Henderson BE, Holly EA, Hu N, Hunter DJ, Innocenti F, Jenab M, Kaaks R, Key TJ, Khaw KT, Klein EA, Krogh V, Kupcinskas J, Kurtz RC, LaCroix A, Landi MT, Landi S, Le Marchand L, Mambrini A, Mannisto S, Milne RL,
Nakamura Y
, Oberg AL, Owzar K, Patel AV, Peeters PH, Peters U, Pezzilli R, Piepoli A, Riboli E, Rothman N, Scarpa A, Shu XO, Silverman DT, Soucek P, Talar-Wojnarowska R, Taylor PR, Theodoropoulos GE, Thornquist M, Tobias GS, Trichopoulos D, Vodicka P, Wactawski-Wende J, Wentzensen N, Wu C, Yu H, Yu K, Zeleniuch-Jacquotte A, Hoover R, Hartge P, Fuchs C, Chanock SJ, Stolzenberg-Solomon RS, Amundadottir LT, Malats N, Büchler MW, Bugert P, Kogevinas M, Porta M, Real FX, Sund M, Tjønneland A. Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. Nat Genet. 2014 Sep; 46(9):994-1000.
PMID:
25086665
; PMCID:
PMC4191666
.
Citations:
176
Fields:
Gen
Genetics
Translation:
Humans
Hazama S, Takenouchi H, Tsunedomi R, Iida M, Suzuki N, Iizuka N, Inoue Y, Sakamoto K, Nakao M, Shindo Y, Kanekiyo S, Tokumitsu Y, Yoshimura K, Maeda N, Maeda K, Maeda Y, Matsui H, Yoshino S,
Nakamura Y
, Fujita Y, Hamamoto Y, Okamoto M, Fujita T, Kawakami Y, Oka M. Predictive biomarkers for the outcome of vaccination of five therapeutic epitope peptides for colorectal cancer. Anticancer Res. 2014 Aug; 34(8):4201-5.
PMID:
25075047
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
PH
Public Health
Deng Z, Matsuda K, Tanikawa C, Lin J, Furukawa Y, Hamamoto R,
Nakamura Y
. Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity. Neoplasia. 2014 Aug; 16(8):656-64.
PMID:
25220593
; PMCID:
PMC4234875
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ji Y, Schaid DJ, Desta Z, Kubo M, Batzler AJ, Snyder K, Mushiroda T, Kamatani N, Ogburn E, Hall-Flavin D, Flockhart D,
Nakamura Y
, Mrazek DA, Weinshilboum RM. Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations. Br J Clin Pharmacol. 2014 Aug; 78(2):373-83.
PMID:
24528284
; PMCID:
PMC4137829
.
Citations:
41
Fields:
Pha
Pharmacology
Translation:
Humans
CT
Clinical Trials
Cai Q, Zhang B, Sung H, Low SK, Kweon SS, Lu W, Shi J, Long J, Wen W, Choi JY, Noh DY, Shen CY, Matsuo K, Teo SH, Kim MK, Khoo US, Iwasaki M, Hartman M, Takahashi A, Ashikawa K, Matsuda K, Shin MH, Park MH, Zheng Y, Xiang YB, Ji BT, Park SK, Wu PE, Hsiung CN, Ito H, Kasuga Y, Kang P, Mariapun S, Ahn SH, Kang HS, Chan KY, Man EP, Iwata H, Tsugane S, Miao H, Liao J,
Nakamura Y
, Kubo M, DRIVE GAME-ON Consortium, Delahanty RJ, Zhang Y, Li B, Li C, Gao YT, Shu XO, Kang D, Zheng W. Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1. Nat Genet. 2014 Aug; 46(8):886-90.
PMID:
25038754
; PMCID:
PMC4127632
.
Citations:
92
Fields:
Gen
Genetics
Translation:
Humans
Cells
Fang H
, Liu X, Choudhury N, Kubo M,
Im HK
, Konkashbaev A,
Cox NJ
,
Ratain MJ
,
Nakamura Y
,
O'Donnell PH
, Ramírez J. Establishment of CYP2D6 reference samples by multiple validated genotyping platforms. Pharmacogenomics J. 2014 Dec; 14(6):564-72.
PMID:
24980783
; PMCID:
PMC4237721
.
Citations:
16
Fields:
Mol
Molecular Biology
Pha
Pharmacology
Translation:
Humans
Cells
Yamaguchi Y, Yamaue H, Okusaka T, Okuno K, Suzuki H, Fujioka T, Otsu A, Ohashi Y, Shimazawa R, Nishio K, Furuse J, Minami H, Tsunoda T, Hayashi Y,
Nakamura Y
, Committee of Guidance for Peptide Vaccines for the Treatment of Cancer, The Japanese Society for Bio. Guidance for peptide vaccines for the treatment of cancer. Cancer Sci. 2014 Jul; 105(7):924-31.
PMID:
25040224
; PMCID:
PMC4317908
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Chin YM, Mushiroda T, Takahashi A, Kubo M, Krishnan G, Yap LF, Teo SH, Lim PV, Yap YY, Pua KC, Kamatani N,
Nakamura Y
, Sam CK, Khoo AS, Malaysian NPC Study Group, Ng CC. HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese. Int J Cancer. 2015 Feb 01; 136(3):678-87.
PMID:
24947555
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Hirokawa M, Morita H, Tajima T, Takahashi A, Ashikawa K, Miya F, Shigemizu D, Ozaki K, Sakata Y, Nakatani D, Suna S, Imai Y, Tanaka T, Tsunoda T, Matsuda K, Kadowaki T,
Nakamura Y
, Nagai R, Komuro I, Kubo M. A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese. Eur J Hum Genet. 2015 Mar; 23(3):374-80.
PMID:
24916648
; PMCID:
PMC4326706
.
Citations:
30
Fields:
Gen
Genetics
Translation:
Humans
Cells
Hamamoto R, Toyokawa G, Nakakido M, Ueda K,
Nakamura Y
. SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation. Cancer Lett. 2014 Aug 28; 351(1):126-33.
PMID:
24880080
.
Citations:
50
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Aguilar H, Urruticoechea A, Halonen P, Kiyotani K, Mushiroda T, Barril X, Serra-Musach J, Islam A, Caizzi L, Di Croce L, Nevedomskaya E, Zwart W, Bostner J, Karlsson E, Fornander T, Sgroi DC, Garcia-Mata R, Jansen MP, Climent F, Gil M, Brunet J, Martrat G, Extremera AI, Figueras A, Balart J, Clarke R, Burnstein KL, Carlson KE, Katzenellenbogen JA, Vizoso M, Esteller M, Villanueva A,
Nakamura Y
, Zembutsu H, Beijersbergen RL, Pujana MA, Pérez Tenorio G, García N, Bonifaci N, Soler MT, Rodríguez-Vida A, Gómez-Baldó L, Rodríguez-Peña AB, Bustelo XR, Stål O. VAV3 mediates resistance to breast cancer endocrine therapy. Breast Cancer Res. 2014 May 28; 16(3):R53.
PMID:
24886537
; PMCID:
PMC4076632
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Yamamoto Y, Miyamoto M, Tatsuda D, Kubo M, Nakagama H,
Nakamura Y
, Satoh H, Matsuda K, Watanabe T, Ohta T. A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability. Cancer Res. 2014 Jul 15; 74(14):3707-15.
PMID:
24830725
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Fujitomo T, Daigo Y, Matsuda K, Ueda K,
Nakamura Y
. Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis. Int J Oncol. 2014 Jul; 45(1):147-56.
PMID:
24806090
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hazama S,
Nakamura Y
, Tanaka H, Hirakawa K, Tahara K, Shimizu R, Ozasa H, Etoh R, Sugiura F, Okuno K, Furuya T, Nishimura T, Sakata K, Yoshimatsu K, Takenouchi H, Tsunedomi R, Inoue Y, Kanekiyo S, Shindo Y, Suzuki N, Yoshino S, Shinozaki H, Kamiya A, Furukawa H, Yamanaka T, Fujita T, Kawakami Y, Oka M. A phase ?I study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study). J Transl Med. 2014 Apr 30; 12:108.
PMID:
24884643
; PMCID:
PMC4021539
.
Citations:
48
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Watanabe H, Uruma T, Tsunoda T, Tazaki G, Suga A,
Nakamura Y
, Yamada S, Tajiri T. Lung metastasis of transitional cell cancer of the urothelium, with fungus ball-like shadows closely resembling aspergilloma: A case report and review of the literature. Oncol Lett. 2014 Jul; 8(1):95-98.
PMID:
24959226
; PMCID:
PMC4063589
.
Citations:
2
Piao L, Kang D, Suzuki T, Masuda A, Dohmae N,
Nakamura Y
, Hamamoto R. The histone methyltransferase SMYD2 methylates PARP1 and promotes poly(ADP-ribosyl)ation activity in cancer cells. Neoplasia. 2014 Mar; 16(3):257-64, 264.e2.
PMID:
24726141
; PMCID:
PMC4094795
.
Citations:
56
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Iinuma H, Fukushima R, Inaba T, Tamura J, Inoue T, Ogawa E, Horikawa M, Ikeda Y, Matsutani N, Takeda K, Yoshida K, Tsunoda T, Ikeda T,
Nakamura Y
, Okinaga K. Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients. J Transl Med. 2014 Apr 03; 12:84.
PMID:
24708624
; PMCID:
PMC4234129
.
Citations:
47
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
CT
Clinical Trials
Goetz MP, Brauch H,
Ratain MJ
,
Cox NJ
,
Nakamura Y
, Weinshilboum R, Ingle JN. Re: Concordance between CYP2D6 genotypes obtained from tumor-derived and germline DNA. J Natl Cancer Inst. 2014 Apr 03; 106(5).
PMID:
24700804
; PMCID:
PMC4580553
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Tomita Y, Yuno A, Tsukamoto H, Senju S, Kuroda Y, Hirayama M, Imamura Y, Yatsuda J, Sayem MA, Irie A, Hamada A, Jono H, Yoshida K, Tsunoda T, Daigo Y, Kohrogi H, Yoshitake Y,
Nakamura Y
, Shinohara M, Nishimura Y. Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant disease. Oncoimmunology. 2014; 3:e28100.
PMID:
25340007
; PMCID:
PMC4203508
.
Citations:
13
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Shigemizu D, Abe T, Morizono T, Johnson TA, Boroevich KA, Hirakawa Y, Ninomiya T, Kiyohara Y, Kubo M,
Nakamura Y
, Maeda S, Tsunoda T. The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort. PLoS One. 2014; 9(3):e92549.
PMID:
24651836
; PMCID:
PMC3961382
.
Citations:
19
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Hazama S,
Nakamura Y
, Takenouchi H, Suzuki N, Tsunedomi R, Inoue Y, Tokuhisa Y, Iizuka N, Yoshino S, Takeda K, Shinozaki H, Kamiya A, Furukawa H, Oka M. A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome. J Transl Med. 2014 Mar 10; 12:63.
PMID:
24612787
; PMCID:
PMC4007571
.
Citations:
51
Fields:
Med
Medicine (General)
Translation:
Humans
PH
Public Health
CT
Clinical Trials
Lin J, Deng Z, Tanikawa C, Shuin T, Miki T, Matsuda K,
Nakamura Y
. Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation. Int J Oncol. 2014 May; 44(5):1490-8.
PMID:
24585183
; PMCID:
PMC4027944
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Zhang B, Jia WH, Matsuo K, Shin A, Xiang YB, Matsuda K, Jee SH, Kim DH, Cheah PY, Ren Z, Cai Q, Long J, Shi J, Wen W, Yang G, Ji BT, Pan ZZ, Matsuda F, Gao YT, Oh JH, Ahn YO, Kubo M, Thean LF, Park EJ, Li HL, Park JW, Jo J, Jeong JY, Hosono S,
Nakamura Y
, Shu XO, Zeng YX, Zheng W. Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians. Int J Cancer. 2014 Aug 15; 135(4):948-55.
PMID:
24448986
; PMCID:
PMC4051826
.
Citations:
38
Fields:
Neo
Neoplasms
Translation:
Humans
Yamaguchi K, Yamaguchi R, Takahashi N, Ikenoue T, Fujii T, Shinozaki M, Tsurita G, Hata K, Niida A, Imoto S, Miyano S,
Nakamura Y
, Furukawa Y. Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer. PLoS One. 2014; 9(1):e85750.
PMID:
24465681
; PMCID:
PMC3894995
.
Citations:
13
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Tomita Y, Yuno A, Tsukamoto H, Senju S, Yoshimura S, Osawa R, Kuroda Y, Hirayama M, Irie A, Hamada A, Jono H, Yoshida K, Tsunoda T, Kohrogi H, Yoshitake Y,
Nakamura Y
, Shinohara M, Nishimura Y. Identification of CDCA1-derived long peptides bearing both CD4+ and CD8+ T-cell epitopes: CDCA1-specific CD4+ T-cell immunity in cancer patients. Int J Cancer. 2014 Jan 15; 134(2):352-66.
PMID:
24734272
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Yoshimura S, Tsunoda T, Osawa R, Harada M, Watanabe T, Hikichi T, Katsuda M, Miyazawa M, Tani M, Iwahashi M, Takeda K, Katagiri T,
Nakamura Y
, Yamaue H. Identification of an HLA-A2-restricted epitope peptide derived from hypoxia-inducible protein 2 (HIG2). PLoS One. 2014; 9(1):e85267.
PMID:
24416375
; PMCID:
PMC3885709
.
Citations:
6
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Miki D, Ochi H, Takahashi A, Hayes CN, Urabe Y, Abe H, Kawaoka T, Tsuge M, Hiraga N, Imamura M, Kawakami Y, Aikata H, Takahashi S, Akuta N, Suzuki F, Ikeda K, Kumada H, Karino Y, Toyota J, Tsunoda T, Kubo M, Kamatani N,
Nakamura Y
, Chayama K. HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study. PLoS One. 2013; 8(12):e84226.
PMID:
24376798
; PMCID:
PMC3871580
.
Citations:
15
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Nakamura Y
, Iwazaki M, Masuda R, Nakano M, Sato T, Shimada A. Lobectomy of pulmonary metastasis of endometrial stromal sarcoma. Tokai J Exp Clin Med. 2013 Dec 20; 38(4):142-5.
PMID:
24318286
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Wu AC, Himes BE, Lasky-Su J, Litonjua A, Peters SP, Lima J, Kubo M, Tamari M,
Nakamura Y
, Qiu W, Weiss ST, Tantisira K. Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics. J Allergy Clin Immunol. 2014 Mar; 133(3):723-8.e3.
PMID:
24280104
; PMCID:
PMC3943570
.
Citations:
12
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Behr ER, Ritchie MD, Tanaka T, Crawford DC, Nicoletti P, Floratos A, Sinner MF, Kannankeril PJ, Wilde AA, Bezzina CR, Schulze-Bahr E, Zumhagen S, Guicheney P, Bishopric NH, Marshall V, Shakir S, Dalageorgou C, Bevan S, Jamshidi Y, Bastiaenen R, Myerburg RJ, Schott JJ, Camm AJ, Steinbeck G, Norris K, Altman RB, Tatonetti NP, Jeffery S, Kubo M,
Nakamura Y
, Shen Y, George AL, Roden DM, Kääb S. Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes. PLoS One. 2013; 8(11):e78511.
PMID:
24223155
; PMCID:
PMC3819377
.
Citations:
29
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Kogure M, Takawa M, Saloura V, Sone K, Piao L, Ueda K, Ibrahim R, Tsunoda T, Sugiyama M, Atomi Y,
Nakamura Y
, Hamamoto R. The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination. Neoplasia. 2013 Nov; 15(11):1251-61.
PMID:
24339737
; PMCID:
PMC3858897
.
Citations:
27
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Low SK, Takahashi A, Ashikawa K, Inazawa J, Miki Y, Kubo M,
Nakamura Y
, Katagiri T. Genome-wide association study of breast cancer in the Japanese population. PLoS One. 2013; 8(10):e76463.
PMID:
24143190
; PMCID:
PMC3797071
.
Citations:
22
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Wang J, Carvajal-Carmona LG, Chu JH, Zauber AG, APC Trial Collaborators, Kubo M, Matsuda K, Dunlop M, Houlston RS, Sieber O, Lipton L, Gibbs P, Martin NG, Montgomery GW, Young J, Baird PN,
Ratain MJ
,
Nakamura Y
, Weiss ST, Tomlinson I, Bertagnolli MM. Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study. Clin Cancer Res. 2013 Dec 01; 19(23):6430-7.
PMID:
24084763
; PMCID:
PMC4037290
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
O'Seaghdha CM, Wu H, Yang Q, Kapur K, Guessous I, Zuber AM, Stoudmann C, Teumer A, Mangino M, Dehghan A, Zhang W, Eiriksdottir G, Li G, Tanaka T, Portas L, Lopez LM, Hayward C, Lohman K, Matsuda K, Padmanabhan S, Firsov D, Sorice R, Ulivi S, Brockhaus AC, Kleber ME, Mahajan A, Ernst FD, Gudnason V, Launer LJ, Mace A, Boerwinckle E, Arking DE, Tanikawa C,
Nakamura Y
, Brown MJ, Gaspoz JM, Theler JM, Siscovick DS, Psaty BM, Bergmann S, Vollenweider P, Vitart V, Wright AF, Zemunik T, Boban M, Kolcic I, Navarro P, Brown EM, Estrada K, Ding J, Harris TB, Bandinelli S, Hernandez D, Singleton AB, Girotto G, Ruggiero D, d'Adamo AP, Robino A, Meitinger T, Meisinger C, Davies G, Starr JM, Chambers JC, Boehm BO, Winkelmann BR, Huang J, Murgia F, Wild SH, Campbell H, Morris AP, Franco OH, Hofman A, Uitterlinden AG, Rivadeneira F, Hannemann A, Biffar R, Hoffmann W, Shin SY, Lescuyer P, Henry H, Schurmann C, SUNLIGHT Consortium, GEFOS Consortium, Munroe PB, Gasparini P, Pirastu N, Ciullo M, Gieger C, Lind L, Spector TD, Smith AV, Rudan I, Wilson JF, Polasek O, Deary IJ, Pirastu M, Ferrucci L, Liu Y, Kestenbaum B, Kooner JS, Witteman JC, Nauck M, Kao WH, Wallaschofski H, Bonny O, Fox CS, Bochud M, Köttgen A, Kutalik Z, Völker U, März W. Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genet. 2013; 9(9):e1003796.
PMID:
24068962
; PMCID:
PMC3778004
.
Citations:
94
Fields:
Gen
Genetics
Translation:
Humans
Animals
Ueda K, Tatsuguchi A, Saichi N, Toyama A, Tamura K, Furihata M, Takata R, Akamatsu S, Igarashi M, Nakayama M, Sato TA, Ogawa O, Fujioka T, Shuin T,
Nakamura Y
, Nakagawa H. Plasma low-molecular-weight proteome profiling identified neuropeptide-Y as a prostate cancer biomarker polypeptide. J Proteome Res. 2013 Oct 04; 12(10):4497-506.
PMID:
23991666
.
Citations:
20
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Dolan ME
, Maitland ML,
O'Donnell PH
,
Nakamura Y
,
Cox NJ
,
Ratain MJ
. Institutional Profile: University of Chicago Center for Personalized Therapeutics: research, education and implementation science. Pharmacogenomics. 2013 Sep; 14(12):1383-7.
PMID:
24024891
; PMCID:
PMC4022693
.
Citations:
5
Fields:
Gen
Genetics
Pha
Pharmacology
Translation:
Humans
Asano K, Matsumoto T, Umeno J, Hirano A, Esaki M, Hosono N, Matsui T, Kiyohara Y,
Nakamura Y
, Kubo M, Kitazono T. Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis. Inflamm Bowel Dis. 2013 Sep; 19(10):2061-8.
PMID:
23917248
.
Citations:
11
Fields:
Gas
Gastroenterology
Translation:
Humans
Pare G, Kubo M, Byrd JB, McCarty CA, Woodard-Grice A, Teo KK, Anand SS, Zuvich RL, Bradford Y, Ross S,
Nakamura Y
, Ritchie M, Brown NJ. Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema. Pharmacogenet Genomics. 2013 Sep; 23(9):470-8.
PMID:
23838604
; PMCID:
PMC3904664
.
Citations:
36
Fields:
Gen
Genetics
Pha
Pharmacology
Translation:
Humans
Matsuda K, Tanikawa C,
Nakamura Y
. [Possible role of genetic factors on reduced risk for gastric cancer among duodenal ulcer patients]. Nihon Rinsho. 2013 Aug; 71(8):1491-6.
PMID:
23967685
.
Citations:
2
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Ratain MJ
,
Nakamura Y
,
Cox NJ
. CYP2D6 genotype and tamoxifen activity: understanding interstudy variability in methodological quality. Clin Pharmacol Ther. 2013 Aug; 94(2):185-7.
PMID:
23872831
; PMCID:
PMC3782290
.
Citations:
22
Fields:
Dru
Drug Therapy
Pha
Pharmacology
Translation:
Humans
Ingle JN, Liu M, Wickerham DL, Schaid DJ, Wang L, Mushiroda T, Kubo M, Costantino JP, Vogel VG, Paik S, Goetz MP, Ames MM, Jenkins GD, Batzler A, Carlson EE, Flockhart DA, Wolmark N,
Nakamura Y
, Weinshilboum RM. Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention. Cancer Discov. 2013 Jul; 3(7):812-25.
PMID:
23764426
; PMCID:
PMC3710533
.
Citations:
51
Fields:
Neo
Neoplasms
Translation:
Humans
Low SK, Chung S, Takahashi A, Zembutsu H, Mushiroda T, Kubo M,
Nakamura Y
. Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Cancer Sci. 2013 Aug; 104(8):1074-82.
PMID:
23648065
; PMCID:
PMC7657179
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
Perera MA, Cavallari LH, Limdi NA, Gamazon ER, Konkashbaev A, Daneshjou R, Pluzhnikov A, Crawford DC, Wang J, Liu N, Tatonetti N, Bourgeois S, Takahashi H, Bradford Y, Burkley BM, Desnick RJ, Halperin JL, Khalifa SI, Langaee TY, Lubitz SA, Nutescu EA, Oetjens M, Shahin MH, Patel SR, Sagreiya H, Tector M, Weck KE, Rieder MJ, Scott SA, Wu AH, Burmester JK, Wadelius M, Deloukas P, Wagner MJ, Mushiroda T, Kubo M, Roden DM,
Cox NJ
, Altman RB, Klein TE,
Nakamura Y
, Johnson JA. Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study. Lancet. 2013 Aug 31; 382(9894):790-6.
PMID:
23755828
; PMCID:
PMC3759580
.
Citations:
126
Fields:
Med
Medicine (General)
Translation:
Humans
Ellinghaus D, Esparza-Gordillo J, Matanovic A, Marenholz I, Schaarschmidt H, Novak N, Michel S, Maintz L, Werfel T, Meyer-Hoffert U, Hotze M, Prokisch H, Heim K, Herder C, Hirota T, Tamari M, Kubo M, Takahashi A,
Nakamura Y
, Tsoi LC, Stuart P, Elder JT, Sun L, Zuo X, Yang S, Zhang X, Hoffmann P, Winkelmann J, Illig T, Boehm BO, Duerr RH, Brand S, McAleer MA, Fahy CM, Kabesch M, Brown S, McLean WH, Irvine AD, Schreiber S, Lee YA, Franke A, Weidinger S, Baurecht H, Rodríguez E, Hübner N, Nöthen MM, Fölster-Holst R, Büning C, Glas J. High-density genotyping study identifies four new susceptibility loci for atopic dermatitis. Nat Genet. 2013 Jul; 45(7):808-12.
PMID:
23727859
; PMCID:
PMC3797441
.
Citations:
69
Fields:
Gen
Genetics
Translation:
Humans
Yasui T, Okada A, Urabe Y, Usami M, Mizuno K, Kubota Y, Tozawa K, Sasaki S, Higashi Y, Sato Y, Kubo M,
Nakamura Y
, Matsuda K, Kohri K. A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population. J Hum Genet. 2013 Sep; 58(9):588-93.
PMID:
23719187
.
Citations:
17
Fields:
Gen
Genetics
Translation:
Humans
Cells
Tomita Y, Yuno A, Tsukamoto H, Senju S, Kuroda Y, Hirayama M, Irie A, Kawahara K, Yatsuda J, Hamada A, Jono H, Yoshida K, Tsunoda T, Kohrogi H, Yoshitake Y,
Nakamura Y
, Shinohara M, Nishimura Y. Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor. Clin Cancer Res. 2013 Aug 15; 19(16):4508-20.
PMID:
23714729
.
Citations:
38
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Daneshjou R, Tatonetti NP, Karczewski KJ, Sagreiya H, Bourgeois S, Drozda K, Burmester JK, Tsunoda T,
Nakamura Y
, Kubo M, Tector M, Limdi NA, Cavallari LH, Perera M, Johnson JA, Klein TE, Altman RB. Pathway analysis of genome-wide data improves warfarin dose prediction. BMC Genomics. 2013; 14 Suppl 3:S11.
PMID:
23819817
; PMCID:
PMC3829086
.
Citations:
9
Fields:
Gen
Genetics
Translation:
Humans
Kusakabe K, Ide N, Daigo Y, Tachibana Y, Itoh T, Yamamoto T, Hashizume H, Hato Y, Higashino K, Okano Y, Sato Y, Inoue M, Iguchi M, Kanazawa T, Ishioka Y, Dohi K, Kido Y, Sakamoto S, Yasuo K, Maeda M, Higaki M, Ueda K, Yoshizawa H, Baba Y, Shiota T, Murai H,
Nakamura Y
. Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125). J Med Chem. 2013 Jun 13; 56(11):4343-56.
PMID:
23634759
.
Citations:
11
Fields:
Che
Chemistry
Translation:
Humans
Animals
Cells
Tanikawa C, Matsuo K, Kubo M, Takahashi A, Ito H, Tanaka H, Yatabe Y, Yamao K, Kamatani N, Tajima K,
Nakamura Y
, Matsuda K. Impact of PSCA variation on gastric ulcer susceptibility. PLoS One. 2013; 8(5):e63698.
PMID:
23704932
; PMCID:
PMC3660579
.
Citations:
4
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Oshita H, Nishino R, Takano A, Fujitomo T, Aragaki M, Kato T, Akiyama H, Tsuchiya E, Kohno N,
Nakamura Y
, Daigo Y. RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer. Mol Cancer Res. 2013 Aug; 11(8):937-51.
PMID:
23686708
.
Citations:
13
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Chung S,
Nakamura Y
. MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells. Cell Cycle. 2013 Jun 01; 12(11):1655-6.
PMID:
23673321
.
Citations:
21
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Kiyotani K, Mushiroda T, Zembutsu H,
Nakamura Y
. Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies. J Hum Genet. 2013 Jun; 58(6):327-33.
PMID:
23657426
.
Citations:
13
Fields:
Gen
Genetics
Translation:
Humans
Tanikawa C, Okada Y, Takahashi A, Oda K, Kamatani N, Kubo M,
Nakamura Y
, Matsuda K. Genome wide association study of age at menarche in the Japanese population. PLoS One. 2013; 8(5):e63821.
PMID:
23667675
; PMCID:
PMC3646805
.
Citations:
20
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Kogure M, Takawa M, Cho HS, Toyokawa G, Hayashi K, Tsunoda T, Kobayashi T, Daigo Y, Sugiyama M, Atomi Y,
Nakamura Y
, Hamamoto R. Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition. Cancer Lett. 2013 Aug 09; 336(1):76-84.
PMID:
23603248
.
Citations:
35
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Saeki H, Hirota T, Nakagawa H, Tsunemi Y, Kato T, Shibata S, Sugaya M, Sato S, Doi S, Miyatake A, Ebe K, Noguchi E, Ebihara T, Amagai M, Esaki H, Takeuchi S, Furue M,
Nakamura Y
, Tamari M. Genetic polymorphisms in the IL22 gene are associated with psoriasis vulgaris in a Japanese population. J Dermatol Sci. 2013 Aug; 71(2):148-50.
PMID:
23664643
.
Citations:
7
Fields:
Der
Dermatology
Translation:
Humans
Lo PH, Urabe Y, Kumar V, Tanikawa C, Koike K, Kato N, Miki D, Chayama K, Kubo M,
Nakamura Y
, Matsuda K. Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk. PLoS One. 2013; 8(4):e61279.
PMID:
23593449
; PMCID:
PMC3623965
.
Citations:
33
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Ishihara M, Araya N, Sato T, Tatsuguchi A, Saichi N, Utsunomiya A,
Nakamura Y
, Nakagawa H, Yamano Y, Ueda K. Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia. Blood. 2013 May 23; 121(21):4340-7.
PMID:
23538341
; PMCID:
PMC3663426
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
Cells
Liu M, Ingle JN, Fridley BL, Buzdar AU, Robson ME, Kubo M, Wang L, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Goetz MP, Northfelt DW, Perez EA, Williard CV, Schaid DJ,
Nakamura Y
, Weinshilboum RM. TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression. Mol Endocrinol. 2013 Apr; 27(4):657-70.
PMID:
23518928
; PMCID:
PMC3607698
.
Citations:
35
Fields:
End
Endocrinology
Mol
Molecular Biology
Translation:
Humans
Cells
CT
Clinical Trials
Kimura K,
Nakamura Y
, Inaba Y, Matsumoto M, Kido Y, Asahara S, Matsuda T, Watanabe H, Maeda A, Inagaki F, Mukai C, Takeda K, Akira S, Ota T, Nakabayashi H, Kaneko S, Kasuga M, Inoue H. Histidine augments the suppression of hepatic glucose production by central insulin action. Diabetes. 2013 Jul; 62(7):2266-77.
PMID:
23474485
; PMCID:
PMC3712067
.
Citations:
29
Fields:
End
Endocrinology
Translation:
Animals
Cells
Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP, Sim X, Weeks DE, Guymer RH, Merriam JE, Francis PJ, Hannum G, Agarwal A, Armbrecht AM, Audo I, Aung T, Barile GR, Benchaboune M, Bird AC, Bishop PN, Branham KE, Brooks M, Brucker AJ, Cade WH, Cain MS, Campochiaro PA, Chan CC, Cheng CY, Chew EY, Chin KA, Chowers I, Clayton DG, Cojocaru R, Conley YP, Cornes BK, Daly MJ, Dhillon B, Edwards AO, Evangelou E, Fagerness J, Ferreyra HA, Friedman JS, Geirsdottir A, George RJ, Gieger C, Gupta N, Hagstrom SA, Harding SP, Haritoglou C, Heckenlively JR, Holz FG, Hughes G, Ioannidis JP, Ishibashi T, Joseph P, Jun G, Kamatani Y, Katsanis N, N Keilhauer C, Khan JC, Kim IK, Kiyohara Y, Klein BE, Klein R, Kovach JL, Kozak I, Lee CJ, Lee KE, Lichtner P, Lotery AJ, Meitinger T, Mitchell P, Moore AT, Morgan DJ, Morrison MA, Myers CE, Naj AC,
Nakamura Y
, Okada Y, Orlin A, Ortube MC, Othman MI, Pappas C, Park KH, Pauer GJ, Peachey NS, Poch O, Priya RR, Reynolds R, Richardson AJ, Ripp R, Rudolph G, Ryu E, Schaumberg DA, Scholl HP, Schwartz SG, Scott WK, Shahid H, Sigurdsson H, Silvestri G, Sivakumaran TA, Smith RT, Sobrin L, Souied EH, Stambolian DE, Stefansson H, Sturgill-Short GM, Takahashi A, Tosakulwong N, Truitt BJ, Tsironi EE, van Duijn CM, Vijaya L, Vingerling JR, Vithana EN, Webster AR, Wichmann HE, Winkler TW, Wong TY, Wright AF, Zelenika D, Zhang M, Zhao L, Zhang K, Klein ML, Hageman GS, Lathrop GM, Stefansson K, Allikmets R, Baird PN, Gorin MB, Wang JJ, Klaver CC, Seddon JM, Pericak-Vance MA, Iyengar SK, Yates JR, Swaroop A, Weber BH, Kubo M, Deangelis MM, Thorsteinsdottir U, Haines JL, Farrer LA, Heid IM, AMD Gene Consortium, Buitendijk GH, Mohand-Saïd S, Sahel JA, Uitterlinden AG, Léveillard T, Abecasis GR. Seven new loci associated with age-related macular degeneration. Nat Genet. 2013 Apr; 45(4):433-9, 439e1-2.
PMID:
23455636
; PMCID:
PMC3739472
.
Citations:
409
Fields:
Gen
Genetics
Translation:
Humans
Hirano A, Yamazaki K, Umeno J, Ashikawa K, Aoki M, Matsumoto T, Nakamura S, Ninomiya T, Matsui T, Hirai F, Kawaguchi T, Takazoe M, Tanaka H, Motoya S, Kiyohara Y, Kitazono T,
Nakamura Y
, Kamatani N, Kubo M. Association study of 71 European Crohn's disease susceptibility loci in a Japanese population. Inflamm Bowel Dis. 2013 Mar; 19(3):526-33.
PMID:
23388546
.
Citations:
34
Fields:
Gas
Gastroenterology
Translation:
Humans
Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ,
Yang JJ
, Mathias RA, Romieu I,
Torgerson DG
, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M,
Nakamura Y
, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG,
Nicolae DL
, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One. 2013; 8(2):e56179.
PMID:
23457522
; PMCID:
PMC3572953
.
Citations:
17
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Shimane K, Kochi Y, Suzuki A, Okada Y, Ishii T, Horita T, Saito K, Okamoto A, Nishimoto N, Myouzen K, Kubo M, Hirakata M, Sumida T, Takasaki Y, Yamada R,
Nakamura Y
, Kamatani N, Yamamoto K. An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes. Rheumatology (Oxford). 2013 Jul; 52(7):1172-82.
PMID:
23407388
.
Citations:
28
Fields:
Rhe
Rheumatology
Translation:
Humans
Betcheva ET, Yosifova AG, Mushiroda T, Kubo M, Takahashi A, Karachanak SK, Zaharieva IT, Hadjidekova SP, Dimova II, Vazharova RV, Stoyanov DS, Milanova VK, Tolev T, Kirov G, Kamatani N, Toncheva DI,
Nakamura Y
. Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene. Psychiatr Genet. 2013 Feb; 23(1):11-9.
PMID:
23142968
.
Citations:
9
Fields:
Gen
Genetics
Psy
Psychiatry
Translation:
Humans
Cells
Urabe Y, Ochi H, Kato N, Kumar V, Takahashi A, Muroyama R, Hosono N, Otsuka M, Tateishi R, Lo PH, Tanikawa C, Omata M, Koike K, Miki D, Abe H, Kamatani N, Toyota J, Kumada H, Kubo M, Chayama K,
Nakamura Y
, Matsuda K. A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region. J Hepatol. 2013 May; 58(5):875-82.
PMID:
23321320
.
Citations:
25
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Unoki M, Masuda A, Dohmae N, Arita K, Yoshimatsu M, Iwai Y, Fukui Y, Ueda K, Hamamoto R, Shirakawa M, Sasaki H,
Nakamura Y
. Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6). J Biol Chem. 2013 Mar 01; 288(9):6053-62.
PMID:
23303181
; PMCID:
PMC3585044
.
Citations:
70
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Kajita Y, Kato T, Tamaki S, Furu M, Takahashi R, Nagayama S, Aoyama T, Nishiyama H, Nakamura E, Katagiri T,
Nakamura Y
, Ogawa O, Toguchida J. The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1). PLoS One. 2013; 8(1):e49709.
PMID:
23326307
; PMCID:
PMC3541374
.
Citations:
9
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Nakamura Y
, Taruno Y, Sugimoto M, Kitamura Y, Seng HL, Kong SM, Ng CH, Chikira M. The DNA binding site specificity and antiproliferative property of ternary Pt(II) and Zn(II) complexes of phenanthroline and N,N'-ethylenediaminediacetic acid. Dalton Trans. 2013 Mar 14; 42(10):3337-45.
PMID:
23299967
.
Citations:
Fields:
Che
Chemistry
Translation:
Humans
Cells
Chung S, Low SK, Zembutsu H, Takahashi A, Kubo M, Sasa M,
Nakamura Y
. A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. Breast Cancer Res. 2013; 15(5):R81.
PMID:
24025145
; PMCID:
PMC3978764
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Yoshimaru T, Komatsu M, Matsuo T, Chen YA, Murakami Y, Mizuguchi K, Mizohata E, Inoue T, Akiyama M, Yamaguchi R, Imoto S, Miyano S, Miyoshi Y, Sasa M,
Nakamura Y
, Katagiri T. Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells. Nat Commun. 2013; 4:2443.
PMID:
24051437
; PMCID:
PMC3791465
.
Citations:
31
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Woodward OM, Okada Y, Tin A, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M,
Nakamura Y
, Tanaka T, Munroe PB, Samani NJ, Jacobs DR, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M, LifeLines Cohort Study, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Viikari J, Hengstenberg C, Nelson CP, CARDIoGRAM Consortium, DIAGRAM Consortium, ICBP Consortium, MAGIC Consortium, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C, Köttgen A, Kutalik Z, Lehtimäki T, Müller C, Esko T, Döring A, Kähönen M, Völzke H, Polašek O, März W, Tönjes A. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet. 2013 Feb; 45(2):145-54.
PMID:
23263486
; PMCID:
PMC3663712
.
Citations:
403
Fields:
Gen
Genetics
Translation:
Humans
Cells
Yamazaki K, Umeno J, Takahashi A, Hirano A, Johnson TA, Kumasaka N, Morizono T, Hosono N, Kawaguchi T, Takazoe M, Yamada T, Suzuki Y, Tanaka H, Motoya S, Hosokawa M, Arimura Y, Shinomura Y, Matsui T, Matsumoto T, Iida M, Tsunoda T,
Nakamura Y
, Kamatani N, Kubo M. A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. Gastroenterology. 2013 Apr; 144(4):781-8.
PMID:
23266558
.
Citations:
71
Fields:
Gas
Gastroenterology
Translation:
Humans
Kamada Y, Kinoshita N, Tsuchiya Y, Kobayashi K, Fujii H, Terao N, Kamihagi K, Koyama N, Yamada S, Daigo Y,
Nakamura Y
, Taniguchi N, Miyoshi E. Reevaluation of a lectin antibody ELISA kit for measuring fucosylated haptoglobin in various conditions. Clin Chim Acta. 2013 Feb 18; 417:48-53.
PMID:
23262369
.
Citations:
16
Fields:
Che
Chemistry
Translation:
Humans
Komatsu M, Yoshimaru T, Matsuo T, Kiyotani K, Miyoshi Y, Tanahashi T, Rokutan K, Yamaguchi R, Saito A, Imoto S, Miyano S,
Nakamura Y
, Sasa M, Shimada M, Katagiri T. Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis. Int J Oncol. 2013 Feb; 42(2):478-506.
PMID:
23254957
.
Citations:
66
Fields:
Neo
Neoplasms
Translation:
Humans
Dabanaka K, Chung S, Nakagawa H,
Nakamura Y
, Okabayashi T, Sugimoto T, Hanazaki K, Furihata M. PKIB expression strongly correlated with phosphorylated Akt expression in breast cancers and also with triple-negative breast cancer subtype. Med Mol Morphol. 2012 Dec; 45(4):229-33.
PMID:
23224602
.
Citations:
7
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Pat
Pathology
Translation:
Humans
Cells
Chung S, Suzuki H, Miyamoto T, Takamatsu N, Tatsuguchi A, Ueda K, Kijima K,
Nakamura Y
, Matsuo Y. Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer. Oncotarget. 2012 Dec; 3(12):1629-40.
PMID:
23283305
; PMCID:
PMC3681500
.
Citations:
85
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Yamamoto T, Tanaka S,
Nakamura Y
, Hashiba R, Ishihara K, Kubo S, Hirohashi K, Ohno K. Colorectal cancer metastasis to the thyroid. Osaka City Med J. 2012 Dec; 58(2):67-75.
PMID:
23610849
.
Citations:
4
Fields:
Med
Medicine (General)
Translation:
Humans
Takahashi M, Furukawa Y, Shimodaira H, Sakayori M, Moriya T, Moriya Y,
Nakamura Y
, Ishioka C. Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome. Fam Cancer. 2012 Dec; 11(4):559-64.
PMID:
22766992
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Wheeler HE, Gamazon ER, Wing C, Njiaju UO, Njoku C, Baldwin RM, Owzar K, Jiang C, Watson D, Shterev I, Kubo M, Zembutsu H, Winer EP, Hudis CA, Shulman LN,
Nakamura Y
,
Ratain MJ
, Kroetz DL, Cancer and Leukemia Group B,
Cox NJ
,
Dolan ME
. Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy. Clin Cancer Res. 2013 Jan 15; 19(2):491-9.
PMID:
23204130
; PMCID:
PMC3549006
.
Citations:
35
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Takata R, Matsuda K, Sugimura J, Obara W, Fujioka T, Okihara K, Takaha N, Miki T, Ashida S, Inoue K, Tanikawa C, Shuin T, Sasaki S, Kojima Y, Kohri K, Kubo M, Yamaguchi M, Ohnishi Y,
Nakamura Y
. Impact of four loci on serum tamsulosin hydrochloride concentration. J Hum Genet. 2013 Jan; 58(1):21-6.
PMID:
23151678
.
Citations:
1
Fields:
Gen
Genetics
Translation:
Humans
Cells
Nyholt DR, Low SK, Anderson CA, Painter JN, Uno S, Morris AP, MacGregor S, Gordon SD, Henders AK, Martin NG, Attia J, Holliday EG, McEvoy M, Scott RJ, Kennedy SH, Treloar SA, Missmer SA, Adachi S, Tanaka K,
Nakamura Y
, Zondervan KT, Zembutsu H, Montgomery GW. Genome-wide association meta-analysis identifies new endometriosis risk loci. Nat Genet. 2012 Dec; 44(12):1355-9.
PMID:
23104006
; PMCID:
PMC3527416
.
Citations:
129
Fields:
Gen
Genetics
Translation:
Humans
Cells
Akamatsu S, Takahashi A, Takata R, Kubo M, Inoue T, Morizono T, Tsunoda T, Kamatani N, Haiman CA, Wan P, Chen GK, Le Marchand L, Kolonel LN, Henderson BE, Fujioka T, Habuchi T,
Nakamura Y
, Ogawa O, Nakagawa H. Reproducibility, performance, and clinical utility of a genetic risk prediction model for prostate cancer in Japanese. PLoS One. 2012; 7(10):e46454.
PMID:
23071574
; PMCID:
PMC3468627
.
Citations:
22
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Sakashita M, Yamada T, Fujieda S, Tanaka S, Doi S, Miyatake A, Enomoto T, Nishiyama C, Nakano N, Maeda K, Okumura K, Ogawa H, Ikeda S, Noguchi E, Sakamoto T, Hizawa N, Ebe K, Saeki H, Sasaki T, Ebihara T, Amagai M, Takeuchi S, Furue M,
Nakamura Y
, Tamari M. Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. Nat Genet. 2012 Nov; 44(11):1222-6.
PMID:
23042114
.
Citations:
149
Fields:
Gen
Genetics
Translation:
Humans
Nakano R, Maekawa T, Abe H, Hayashida Y, Ochi H, Tsunoda T, Kumada H, Kamatani N,
Nakamura Y
, Chayama K. Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C. J Gen Virol. 2013 Jan; 94(Pt 1):81-89.
PMID:
23034592
.
Citations:
4
Fields:
Vir
Virology
Translation:
Humans
Cells
Toyama A, Nakagawa H, Matsuda K, Sato TA,
Nakamura Y
, Ueda K. Quantitative structural characterization of local N-glycan microheterogeneity in therapeutic antibodies by energy-resolved oxonium ion monitoring. Anal Chem. 2012 Nov 20; 84(22):9655-62.
PMID:
23004563
.
Citations:
15
Fields:
Che
Chemistry Techniques
Translation:
Humans
Cells
Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, Okada Y, Polasek O, Westra HJ, Wang YA, Del Greco M F, Glazer NL, Kapur K, Kema IP, Lopez LM, Schillert A, Smith AV, Winkler CA, Zgaga L, LifeLines Cohort Study, Bandinelli S, Bergmann S, Boban M, Bochud M, Chen YD, Davies G, Dehghan A, Ding J, Doering A, Durda JP, Ferrucci L, Franco OH, Franke L, Gunjaca G, Hofman A, Hsu FC, Kolcic I, Kraja A, Kubo M, Lackner KJ, Launer L, Loehr LR, Li G, Meisinger C,
Nakamura Y
, Schwienbacher C, Starr JM, Takahashi A, Torlak V, Vitart V, Waldenberger M, Wild PS, Kirin M, Zeller T, Zemunik T, Zhang Q, Ziegler A, Blankenberg S, Boerwinkle E, Borecki IB, Campbell H, Deary IJ, Frayling TM, Gieger C, Harris TB, Hicks AA, Koenig W, O' Donnell CJ, Fox CS, Pramstaller PP, Psaty BM, Reiner AP, Rotter JI, Rudan I, Snieder H, Tanaka T, van Duijn CM, Vollenweider P, Waeber G, Wilson JF, Witteman JC, Wolffenbuttel BH, Wright AF, Wu Q, Liu Y, Jenny NS, North KE, Felix JF, Alizadeh BZ, Cupples LA, Perry JR, Morris AP, Uitterlinden AG. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet. 2012 Oct 05; 91(4):744-53.
PMID:
23022100
; PMCID:
PMC3484648
.
Citations:
45
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Fukawa T, Ono M, Matsuo T, Uehara H, Miki T,
Nakamura Y
, Kanayama HO, Katagiri T. DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas. Cancer Res. 2012 Nov 15; 72(22):5867-77.
PMID:
23019224
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Giacomini KM, Yee SW,
Ratain MJ
, Weinshilboum RM, Kamatani N,
Nakamura Y
. Pharmacogenomics and patient care: one size does not fit all. Sci Transl Med. 2012 Sep 26; 4(153):153ps18.
PMID:
23019654
; PMCID:
PMC3963516
.
Citations:
27
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Kumasaka N, Aoki M, Okada Y, Takahashi A, Ozaki K, Mushiroda T, Hirota T, Tamari M, Tanaka T,
Nakamura Y
, Kamatani N, Kubo M. Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population. PLoS One. 2012; 7(9):e44507.
PMID:
23049750
; PMCID:
PMC3458030
.
Citations:
26
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Kang D, Cho HS, Toyokawa G, Kogure M, Yamane Y, Iwai Y, Hayami S, Tsunoda T, Field HI, Matsuda K, Neal DE, Ponder BA, Maehara Y,
Nakamura Y
, Hamamoto R. The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis. Genes Chromosomes Cancer. 2013 Feb; 52(2):126-39.
PMID:
23011637
.
Citations:
39
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Kumar V, Yi Lo PH, Sawai H, Kato N, Takahashi A, Deng Z, Urabe Y, Mbarek H, Tokunaga K, Tanaka Y, Sugiyama M, Mizokami M, Muroyama R, Tateishi R, Omata M, Koike K, Tanikawa C, Kamatani N, Kubo M,
Nakamura Y
, Matsuda K. Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma. PLoS One. 2012; 7(9):e44743.
PMID:
23024757
; PMCID:
PMC3443094
.
Citations:
50
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Myouzen K, Kochi Y, Okada Y, Terao C, Suzuki A, Ikari K, Tsunoda T, Takahashi A, Kubo M, Taniguchi A, Matsuda F, Ohmura K, Momohara S, Mimori T, Yamanaka H, Kamatani N, Yamada R,
Nakamura Y
, Yamamoto K. Functional variants in NFKBIE and RTKN2 involved in activation of the NF-?B pathway are associated with rheumatoid arthritis in Japanese. PLoS Genet. 2012 Sep; 8(9):e1002949.
PMID:
23028356
; PMCID:
PMC3441678
.
Citations:
31
Fields:
Gen
Genetics
Translation:
Humans
Cells
Elgazzar S, Zembutsu H, Takahashi A, Kubo M, Aki F, Hirata K, Takatsuka Y, Okazaki M, Ohsumi S, Yamakawa T, Sasa M, Katagiri T, Miki Y,
Nakamura Y
. A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese. J Hum Genet. 2012 Dec; 57(12):766-71.
PMID:
22951594
.
Citations:
21
Fields:
Gen
Genetics
Translation:
Humans
Cells
Masuda R, Kijima H, Imamura N, Aruga N,
Nakamura Y
, Masuda D, Takeichi H, Kato N, Nakagawa T, Tanaka M, Inokuchi S, Iwazaki M. Tumor budding is a significant indicator of a poor prognosis in lung squamous cell carcinoma patients. Mol Med Rep. 2012 11; 6(5):937-43.
PMID:
22940760
; PMCID:
PMC3493086
.
Citations:
39
Fields:
Mol
Molecular Biology
Translation:
Humans
Cheng I, Chen GK, Nakagawa H, He J, Wan P, Laurie CC, Shen J, Sheng X, Pooler LC, Crenshaw AT, Mirel DB, Takahashi A, Kubo M,
Nakamura Y
, Al Olama AA, Benlloch S, Donovan JL, Guy M, Hamdy FC, Kote-Jarai Z, Neal DE, Wilkens LR, Monroe KR, Stram DO, Muir K, Eeles RA, Easton DF, Kolonel LN, Henderson BE, Haiman CA, Le Marchand L. Evaluating genetic risk for prostate cancer among Japanese and Latinos. Cancer Epidemiol Biomarkers Prev. 2012 Nov; 21(11):2048-58.
PMID:
22923026
; PMCID:
PMC3494732
.
Citations:
35
Fields:
Bio
Biochemistry
Epi
Epidemiology
Neo
Neoplasms
Translation:
Humans
Nguyen MH, Ueda K,
Nakamura Y
, Daigo Y. Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis. Int J Oncol. 2012 Oct; 41(4):1285-96.
PMID:
22895565
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Nakamura Y
,
Ratain MJ
,
Cox NJ
, McLeod HL, Kroetz DL, Flockhart DA. Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial. J Natl Cancer Inst. 2012 Aug 22; 104(16):1264; author reply 1266-8.
PMID:
22851270
.
Citations:
30
Fields:
Neo
Neoplasms
Translation:
Humans
Baldwin RM, Owzar K, Zembutsu H, Chhibber A, Kubo M, Jiang C, Watson D, Eclov RJ, Mefford J, McLeod HL, Friedman PN, Hudis CA, Winer EP, Jorgenson EM, Witte JS, Shulman LN,
Nakamura Y
,
Ratain MJ
, Kroetz DL. A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. Clin Cancer Res. 2012 Sep 15; 18(18):5099-109.
PMID:
22843789
; PMCID:
PMC3445665
.
Citations:
99
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Masuzawa T, Fujiwara Y, Okada K, Nakamura A, Takiguchi S, Nakajima K, Miyata H, Yamasaki M, Kurokawa Y, Osawa R, Takeda K, Yoshida K, Tsunoda T,
Nakamura Y
, Mori M, Doki Y. Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer. Int J Oncol. 2012 Oct; 41(4):1297-304.
PMID:
22842485
.
Citations:
46
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H, Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W, Kooner JS, KidneyGen Consortium, CKDGen Consortium, Albrecht E, GUGC consortium, Yamamoto K, Kubo M,
Nakamura Y
, Kamatani N, Kato N, He J, Chen YT, Cho YS, Tai ES, Tanaka T. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet. 2012 Jul 15; 44(8):904-9.
PMID:
22797727
; PMCID:
PMC4737645
.
Citations:
168
Fields:
Gen
Genetics
Translation:
Humans
Shiraishi K, Kunitoh H, Daigo Y, Takahashi A, Goto K, Sakamoto H, Ohnami S, Shimada Y, Ashikawa K, Saito A, Watanabe S, Tsuta K, Kamatani N, Yoshida T,
Nakamura Y
, Yokota J, Kubo M, Kohno T. A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population. Nat Genet. 2012 Jul 15; 44(8):900-3.
PMID:
22797724
.
Citations:
108
Fields:
Gen
Genetics
Translation:
Humans
Kono K, Iinuma H, Akutsu Y, Tanaka H, Hayashi N, Uchikado Y, Noguchi T, Fujii H, Okinaka K, Fukushima R, Matsubara H, Ohira M, Baba H, Natsugoe S, Kitano S, Takeda K, Yoshida K, Tsunoda T,
Nakamura Y
. Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens. J Transl Med. 2012 Jul 09; 10:141.
PMID:
22776426
; PMCID:
PMC3403921
.
Citations:
78
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
PH
Public Health
CT
Clinical Trials
Himes BE, Jiang X, Hu R, Wu AC, Lasky-Su JA, Klanderman BJ, Ziniti J, Senter-Sylvia J, Lima JJ, Irvin CG, Peters SP, Meyers DA, Bleecker ER, Kubo M, Tamari M,
Nakamura Y
, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Hanrahan JP, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Panettieri RA, Markezich A, Israel E, Carey VJ, Tantisira KG, Litonjua AA, Lu Q, Weiss ST. Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. PLoS Genet. 2012 Jul; 8(7):e1002824.
PMID:
22792082
; PMCID:
PMC3390407
.
Citations:
55
Fields:
Gen
Genetics
Translation:
Humans
Cells
Fujitomo T, Daigo Y, Matsuda K, Ueda K,
Nakamura Y
. Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis. Cancer Res. 2012 Aug 15; 72(16):4110-8.
PMID:
22719065
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Sawai H, Nishida N, Mbarek H, Matsuda K, Mawatari Y, Yamaoka M, Hige S, Kang JH, Abe K, Mochida S, Watanabe M, Kurosaki M, Asahina Y, Izumi N, Honda M, Kaneko S, Tanaka E, Matsuura K, Itoh Y, Mita E, Korenaga M, Hino K, Murawaki Y, Hiasa Y, Ide T, Ito K, Sugiyama M, Ahn SH, Han KH, Park JY, Yuen MF,
Nakamura Y
, Tanaka Y, Mizokami M, Tokunaga K. No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations. BMC Med Genet. 2012 Jun 19; 13:47.
PMID:
22712471
; PMCID:
PMC3407509
.
Citations:
23
Fields:
Gen
Genetics
Translation:
Humans
Cells
Osawa R, Tsunoda T, Yoshimura S, Watanabe T, Miyazawa M, Tani M, Takeda K, Nakagawa H,
Nakamura Y
, Yamaue H. Identification of HLA-A24-restricted novel T Cell epitope peptides derived from P-cadherin and kinesin family member 20A. J Biomed Biotechnol. 2012; 2012:848042.
PMID:
22778556
; PMCID:
PMC3388625
.
Citations:
13
Fields:
Bio
Biotechnology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Akuta N, Suzuki F, Hirakawa M, Kawamura Y, Yatsuji H, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Chayama K,
Nakamura Y
, Kumada H. Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment. Intervirology. 2012; 55(6):417-25.
PMID:
21325786
.
Citations:
10
Fields:
Vir
Virology
Translation:
Humans
Cells
Kusakabe K, Ide N, Daigo Y, Itoh T, Higashino K, Okano Y, Tadano G, Tachibana Y, Sato Y, Inoue M, Wada T, Iguchi M, Kanazawa T, Ishioka Y, Dohi K, Tagashira S, Kido Y, Sakamoto S, Yasuo K, Maeda M, Yamamoto T, Higaki M, Endoh T, Ueda K, Shiota T, Murai H,
Nakamura Y
. Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation. ACS Med Chem Lett. 2012 Jul 12; 3(7):560-4.
PMID:
24900510
; PMCID:
PMC4025729
.
Citations:
10
Cho HS, Hayami S, Toyokawa G, Maejima K, Yamane Y, Suzuki T, Dohmae N, Kogure M, Kang D, Neal DE, Ponder BA, Yamaue H,
Nakamura Y
, Hamamoto R. RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation. Neoplasia. 2012 Jun; 14(6):476-86.
PMID:
22787429
; PMCID:
PMC3394190
.
Citations:
106
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Aoki M, Hosono N, Takata S,
Nakamura Y
, Kamatani N, Kubo M. New pharmacogenetic test for detecting an HLA-A*31: 01 allele using the InvaderPlus assay. Pharmacogenet Genomics. 2012 Jun; 22(6):441-6.
PMID:
22453764
.
Citations:
5
Fields:
Gen
Genetics
Pha
Pharmacology
Translation:
Humans
Fujimoto A, Totoki Y, Abe T, Boroevich KA, Hosoda F, Nguyen HH, Aoki M, Hosono N, Kubo M, Miya F, Arai Y, Takahashi H, Shirakihara T, Nagasaki M, Shibuya T, Nakano K, Watanabe-Makino K, Tanaka H, Nakamura H, Kusuda J, Ojima H, Shimada K, Okusaka T, Ueno M, Shigekawa Y, Kawakami Y, Arihiro K, Ohdan H, Gotoh K, Ishikawa O, Ariizumi S, Yamamoto M, Yamada T, Chayama K, Kosuge T, Yamaue H, Kamatani N, Miyano S, Nakagama H,
Nakamura Y
, Tsunoda T, Shibata T, Nakagawa H. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet. 2012 May 27; 44(7):760-4.
PMID:
22634756
.
Citations:
485
Fields:
Gen
Genetics
Translation:
Humans
Cells
Dunlop MG, Dobbins SE, Farrington SM, Jones AM, Palles C, Whiffin N, Tenesa A, Spain S, Broderick P, Ooi LY, Domingo E, Smillie C, Henrion M, Frampton M, Martin L, Grimes G, Gorman M, Semple C, Ma YP, Barclay E, Prendergast J, Cazier JB, Olver B, Penegar S, Lubbe S, Chander I, Carvajal-Carmona LG, Ballereau S, Lloyd A, Vijayakrishnan J, Zgaga L, Rudan I, Theodoratou E, Colorectal Tumour Gene Identification (CORGI) Consortium, Starr JM, Deary I, Kirac I, Kovacevic D, Aaltonen LA, Renkonen-Sinisalo L, Mecklin JP, Matsuda K,
Nakamura Y
, Okada Y, Gallinger S, Duggan DJ, Conti D, Newcomb P, Hopper J, Jenkins MA, Schumacher F, Casey G, Easton D, Shah M, Pharoah P, Lindblom A, Liu T, Swedish Low-Risk Colorectal Cancer Study Group, Smith CG, West H, Cheadle JP, COIN Collaborative Group, Midgley R, Kerr DJ, Campbell H, Tomlinson IP, Houlston RS. Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nat Genet. 2012 May 27; 44(7):770-6.
PMID:
22634755
; PMCID:
PMC4747430
.
Citations:
148
Fields:
Gen
Genetics
Translation:
Humans
Obara W, Ohsawa R, Kanehira M, Takata R, Tsunoda T, Yoshida K, Takeda K, Katagiri T,
Nakamura Y
, Fujioka T. Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer. Jpn J Clin Oncol. 2012 Jul; 42(7):591-600.
PMID:
22636067
.
Citations:
33
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Takawa M, Cho HS, Hayami S, Toyokawa G, Kogure M, Yamane Y, Iwai Y, Maejima K, Ueda K, Masuda A, Dohmae N, Field HI, Tsunoda T, Kobayashi T, Akasu T, Sugiyama M, Ohnuma S, Atomi Y, Ponder BA,
Nakamura Y
, Hamamoto R. Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. Cancer Res. 2012 Jul 01; 72(13):3217-27.
PMID:
22556262
.
Citations:
99
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Mahasirimongkol S, Yanai H, Mushiroda T, Promphittayarat W, Wattanapokayakit S, Phromjai J, Yuliwulandari R, Wichukchinda N, Yowang A, Yamada N, Kantipong P, Takahashi A, Kubo M, Sawanpanyalert P, Kamatani N,
Nakamura Y
, Tokunaga K. Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis. J Hum Genet. 2012 Jun; 57(6):363-7.
PMID:
22551897
.
Citations:
60
Fields:
Gen
Genetics
Translation:
Humans
Ellinor PT, Lunetta KL, Albert CM, Glazer NL, Ritchie MD, Smith AV, Arking DE, Krijthe BP, Lubitz SA, Bis JC, Chung MK, Ozaki K, Roberts JD, Smith JG, Pfeufer A, Sinner MF, Lohman K, Ding J, Smith NL, Smith JD, Rienstra M, Rice KM, Van Wagoner DR, Magnani JW, Wakili R, Clauss S, Rotter JI, Steinbeck G, Launer LJ, Davies RW, Borkovich M, Harris TB, Lin H, Milan DJ, Hofman A, Boerwinkle E, Chen LY, Soliman EZ, Voight BF, Li G, Chakravarti A, Kubo M, Tedrow UB, Rose LM, Ridker PM, Conen D, Tsunoda T, Furukawa T, Sotoodehnia N, Xu S, Kamatani N, Levy D,
Nakamura Y
, Parvez B, Mahida S, Furie KL, Rosand J, Muhammad R, Psaty BM, Meitinger T, Perz S, Wichmann HE, Witteman JC, Kao WH, Kathiresan S, Roden DM, Uitterlinden AG, Rivadeneira F, McKnight B, Newman AB, Liu Y, Gollob MH, Melander O, Tanaka T, Stricker BH, Felix SB, Alonso A, Darbar D, Barnard J, Chasman DI, Heckbert SR, Benjamin EJ, Gudnason V, Müller-Nurasyid M, Dörr M, Völker U, Völzke H, Sjögren M, Kääb S. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet. 2012 Apr 29; 44(6):670-5.
PMID:
22544366
; PMCID:
PMC3366038
.
Citations:
307
Fields:
Gen
Genetics
Translation:
Humans
Osman W, Okada Y, Kamatani Y, Kubo M, Matsuda K,
Nakamura Y
. Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese. PLoS One. 2012; 7(4):e32683.
PMID:
22558069
; PMCID:
PMC3338726
.
Citations:
24
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Kiyotani K, Uno S, Mushiroda T, Takahashi A, Kubo M, Mitsuhata N, Ina S, Kihara C, Kimura Y, Yamaue H, Hirata K,
Nakamura Y
, Zembutsu H. A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy. Pharmacogenet Genomics. 2012 Apr; 22(4):229-35.
PMID:
22293537
.
Citations:
8
Fields:
Gen
Genetics
Pha
Pharmacology
Translation:
Humans
Abo R, Hebbring S, Ji Y, Zhu H, Zeng ZB, Batzler A, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Fridley B, Schaid D, Kamatani N,
Nakamura Y
, Kubo M, Mushiroda T, Kaddurah-Daouk R, Mrazek DA, Weinshilboum RM. Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics. Pharmacogenet Genomics. 2012 Apr; 22(4):247-53.
PMID:
22322242
; PMCID:
PMC3303952
.
Citations:
28
Fields:
Gen
Genetics
Pha
Pharmacology
Translation:
Humans
Yamaguchi-Kabata Y, Tsunoda T, Kumasaka N, Takahashi A, Hosono N, Kubo M,
Nakamura Y
, Kamatani N. Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes. J Hum Genet. 2012 May; 57(5):326-34.
PMID:
22456480
.
Citations:
2
Fields:
Gen
Genetics
Translation:
Humans
Imamura M, Maeda S, Yamauchi T, Hara K, Yasuda K, Morizono T, Takahashi A, Horikoshi M, Nakamura M, Fujita H, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Ohshige T, Omori S, Iwata M, Hirose H, Kaku K, Ito C, Tanaka Y, Tobe K, Kashiwagi A, Kawamori R, Kasuga M, Kamatani N, Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium,
Nakamura Y
, Kadowaki T. A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. Hum Mol Genet. 2012 Jul 01; 21(13):3042-9.
PMID:
22456796
.
Citations:
54
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Okada Y, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Kawaguchi T, Stahl EA, Kurreeman FA, Nishida N, Ohmiya H, Myouzen K, Takahashi M, Sawada T, Nishioka Y, Yukioka M, Matsubara T, Wakitani S, Teshima R, Tohma S, Takasugi K, Shimada K, Murasawa A, Honjo S, Matsuo K, Tanaka H, Tajima K, Suzuki T, Iwamoto T, Kawamura Y, Tanii H, Okazaki Y, Sasaki T, Gregersen PK, Padyukov L, Worthington J, Siminovitch KA, Lathrop M, Taniguchi A, Takahashi A, Tokunaga K, Kubo M,
Nakamura Y
, Kamatani N, Mimori T, Plenge RM, Yamanaka H, Momohara S, Yamada R, Matsuda F, Yamamoto K. Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. Nat Genet. 2012 Mar 25; 44(5):511-6.
PMID:
22446963
.
Citations:
173
Fields:
Gen
Genetics
Translation:
Humans
Onouchi Y, Ozaki K, Burns JC, Shimizu C, Terai M, Hamada H, Honda T, Suzuki H, Suenaga T, Takeuchi T, Yoshikawa N, Suzuki Y, Yasukawa K, Ebata R, Higashi K, Saji T, Kemmotsu Y, Takatsuki S, Ouchi K, Kishi F, Yoshikawa T, Nagai T, Hamamoto K, Sato Y, Honda A, Kobayashi H, Sato J, Shibuta S, Miyawaki M, Oishi K, Yamaga H, Aoyagi N, Iwahashi S, Miyashita R, Murata Y, Sasago K, Takahashi A, Kamatani N, Kubo M, Tsunoda T, Hata A,
Nakamura Y
, Tanaka T, Japan Kawasaki Disease Genome Consortium, US Kawasaki Disease Genetics Consortium. A genome-wide association study identifies three new risk loci for Kawasaki disease. Nat Genet. 2012 Mar 25; 44(5):517-21.
PMID:
22446962
.
Citations:
155
Fields:
Gen
Genetics
Translation:
Humans
Osman W, Low SK, Takahashi A, Kubo M,
Nakamura Y
. A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma. Hum Mol Genet. 2012 Jun 15; 21(12):2836-42.
PMID:
22419738
.
Citations:
73
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Liu M, Wang L, Bongartz T, Hawse JR, Markovic SN, Schaid DJ, Mushiroda T, Kubo M,
Nakamura Y
, Kamatani N, Goss PE, Ingle JN, Weinshilboum RM. Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression. Breast Cancer Res. 2012 Mar 09; 14(2):R41.
PMID:
22405131
; PMCID:
PMC3446375
.
Citations:
39
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Jongjaroenprasert W, Phusantisampan T, Mahasirimongkol S, Mushiroda T, Hirankarn N, Snabboon T, Chanprasertyotin S, Tantiwong P, Soonthornpun S, Rattanapichart P, Mamanasiri S, Himathongkam T, Ongphiphadhanakul B, Takahashi A, Kamatani N, Kubo M,
Nakamura Y
. A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis. J Hum Genet. 2012 May; 57(5):301-4.
PMID:
22399142
.
Citations:
15
Fields:
Gen
Genetics
Translation:
Humans
Cells
Iida A, Hosono N, Sano M, Kamei T, Oshima S, Tokuda T, Nakajima M, Kubo M,
Nakamura Y
, Ikegawa S. Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese. Neurobiol Aging. 2012 Aug; 33(8):1843.e19-24.
PMID:
22402017
.
Citations:
22
Fields:
Ger
Geriatrics
Neu
Neurology
Phy
Physiology
Translation:
Humans
Tanikawa C, Urabe Y, Matsuo K, Kubo M, Takahashi A, Ito H, Tajima K, Kamatani N,
Nakamura Y
, Matsuda K. A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. Nat Genet. 2012 Mar 04; 44(4):430-4, S1-2.
PMID:
22387998
.
Citations:
68
Fields:
Gen
Genetics
Translation:
Humans
Urabe Y, Tanikawa C, Takahashi A, Okada Y, Morizono T, Tsunoda T, Kamatani N, Kohri K, Chayama K, Kubo M,
Nakamura Y
, Matsuda K. A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1. PLoS Genet. 2012; 8(3):e1002541.
PMID:
22396660
; PMCID:
PMC3291538
.
Citations:
40
Fields:
Gen
Genetics
Translation:
Humans
Cells
Akamatsu S, Takata R, Haiman CA, Takahashi A, Inoue T, Kubo M, Furihata M, Kamatani N, Inazawa J, Chen GK, Kolonel LN, Katoh T, Yamano Y, Yamakado M, Takahashi H, Yamada H, Egawa S, Fujioka T, Henderson BE, Habuchi T, Ogawa O,
Nakamura Y
, Nakagawa H, Le Marchand L. Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese. Nat Genet. 2012 Feb 26; 44(4):426-9, S1.
PMID:
22366784
.
Citations:
65
Fields:
Gen
Genetics
Translation:
Humans
Cells
Toyama A, Suzuki A, Shimada T, Aoki C, Aoki Y, Umino Y,
Nakamura Y
, Aoki D, Sato TA. Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers. Cancer Sci. 2012 Apr; 103(4):747-55.
PMID:
22321069
; PMCID:
PMC7659196
.
Citations:
35
Fields:
Neo
Neoplasms
Translation:
Humans
Wen W, Cho YS, Zheng W, Dorajoo R, Kato N, Qi L, Chen CH, Delahanty RJ, Okada Y, Tabara Y, Gu D, Zhu D, Haiman CA, Mo Z, Gao YT, Saw SM, Go MJ, Takeuchi F, Chang LC, Kokubo Y, Liang J, Hao M, Zhang Y, Hu Y, Wong TY, Long J, Han BG, Kubo M, Yamamoto K, Su MH, Miki T, Henderson BE, Song H, Tan A, He J, Ng DP, Cai Q, Tsunoda T, Tsai FJ, Iwai N, Chen GK, Shi J, Xu J, Sim X, Xiang YB, Maeda S, Ong RT, Li C,
Nakamura Y
, Aung T, Kamatani N, Liu JJ, Lu W, Yokota M, Seielstad M, Fann CS, Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Wu JY, Lee JY, Hu FB, Tanaka T, Tai ES, Shu XO, Le Marchand L. Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet. 2012 Feb 19; 44(3):307-11.
PMID:
22344219
; PMCID:
PMC3288728
.
Citations:
197
Fields:
Gen
Genetics
Translation:
Humans
Okada Y, Kubo M, Ohmiya H, Takahashi A, Kumasaka N, Hosono N, Maeda S, Wen W, Dorajoo R, Go MJ, Zheng W, Kato N, Wu JY, Lu Q, GIANT consortium, Tsunoda T, Yamamoto K,
Nakamura Y
, Kamatani N, Tanaka T. Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. Nat Genet. 2012 Feb 19; 44(3):302-6.
PMID:
22344221
; PMCID:
PMC3838874
.
Citations:
123
Fields:
Gen
Genetics
Translation:
Humans
Cells
Tanikawa C, Espinosa M, Suzuki A, Masuda K, Yamamoto K, Tsuchiya E, Ueda K, Daigo Y,
Nakamura Y
, Matsuda K. Regulation of histone modification and chromatin structure by the p53-PADI4 pathway. Nat Commun. 2012 Feb 14; 3:676.
PMID:
22334079
.
Citations:
76
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Cells
Cha PC, Zembutsu H, Takahashi A, Kubo M, Kamatani N,
Nakamura Y
. A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population. J Hum Genet. 2012 Apr; 57(4):235-7.
PMID:
22318345
.
Citations:
17
Fields:
Gen
Genetics
Translation:
Humans
Nguyen HH, Takata R, Akamatsu S, Shigemizu D, Tsunoda T, Furihata M, Takahashi A, Kubo M, Kamatani N, Ogawa O, Fujioka T,
Nakamura Y
, Nakagawa H. IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility. Hum Mol Genet. 2012 May 01; 21(9):2076-85.
PMID:
22323358
.
Citations:
26
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Tanikawa C, Nakagawa H, Furukawa Y,
Nakamura Y
, Matsuda K. CLCA2 as a p53-inducible senescence mediator. Neoplasia. 2012 Feb; 14(2):141-9.
PMID:
22431922
; PMCID:
PMC3306259
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Nakagawa H, Akamatsu S, Takata R, Takahashi A, Kubo M,
Nakamura Y
. Prostate cancer genomics, biology, and risk assessment through genome-wide association studies. Cancer Sci. 2012 Apr; 103(4):607-13.
PMID:
22181854
; PMCID:
PMC7659324
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Low SK, Takahashi A, Cha PC, Zembutsu H, Kamatani N, Kubo M,
Nakamura Y
. Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA. Hum Mol Genet. 2012 May 01; 21(9):2102-10.
PMID:
22286173
.
Citations:
56
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Okada Y, Shimane K, Kochi Y, Tahira T, Suzuki A, Higasa K, Takahashi A, Horita T, Atsumi T, Ishii T, Okamoto A, Fujio K, Hirakata M, Amano H, Kondo Y, Ito S, Takada K, Mimori A, Saito K, Kamachi M, Kawaguchi Y, Ikari K, Mohammed OW, Matsuda K, Terao C, Ohmura K, Myouzen K, Hosono N, Tsunoda T, Nishimoto N, Mimori T, Matsuda F, Tanaka Y, Sumida T, Yamanaka H, Takasaki Y, Koike T, Horiuchi T, Hayashi K, Kubo M, Kamatani N, Yamada R,
Nakamura Y
, Yamamoto K. A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese. PLoS Genet. 2012 Jan; 8(1):e1002455.
PMID:
22291604
; PMCID:
PMC3266877
.
Citations:
56
Fields:
Gen
Genetics
Translation:
Humans
Chang WC, Lee CH, Hirota T, Wang LF, Doi S, Miyatake A, Enomoto T, Tomita K, Sakashita M, Yamada T, Fujieda S, Ebe K, Saeki H, Takeuchi S, Furue M, Chen WC, Chiu YC, Chang WP, Hong CH, Hsi E, Juo SH, Yu HS,
Nakamura Y
, Tamari M. ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations. PLoS One. 2012; 7(1):e29387.
PMID:
22253717
; PMCID:
PMC3258251
.
Citations:
22
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Koinuma J, Akiyama H, Fujita M, Hosokawa M, Tsuchiya E, Kondo S,
Nakamura Y
, Daigo Y. Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis. Cancer Sci. 2012 Mar; 103(3):577-86.
PMID:
22129094
; PMCID:
PMC7713625
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Yoshioka H, Yamamoto S, Hanaoka H, Iida Y, Paudyal P, Higuchi T, Tominaga H, Oriuchi N, Nakagawa H, Shiba Y, Yoshida K, Osawa R, Katagiri T, Tsunoda T,
Nakamura Y
, Endo K. In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy. Cancer Immunol Immunother. 2012 Aug; 61(8):1211-20.
PMID:
22223257
; PMCID:
PMC11029081
.
Citations:
10
Fields:
All
Allergy and Immunology
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Cho HS, Shimazu T, Toyokawa G, Daigo Y, Maehara Y, Hayami S, Ito A, Masuda K, Ikawa N, Field HI, Tsuchiya E, Ohnuma S, Ponder BA, Yoshida M,
Nakamura Y
, Hamamoto R. Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B. Nat Commun. 2012; 3:1072.
PMID:
22990868
; PMCID:
PMC3658001
.
Citations:
66
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Cells
Yew PY, Mushiroda T, Kiyotani K, Govindasamy GK, Yap LF, Teo SH, Lim PV, Govindaraju S, Ratnavelu K, Sam CK, Yap YY, Khoo AS, Pua KC,
Nakamura Y
, Malaysian NPC Study Group, Ng CC. Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese. Mol Carcinog. 2012 Oct; 51 Suppl 1:E74-82.
PMID:
22213098
.
Citations:
8
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cho HS, Toyokawa G, Daigo Y, Hayami S, Masuda K, Ikawa N, Yamane Y, Maejima K, Tsunoda T, Field HI, Kelly JD, Neal DE, Ponder BA, Maehara Y,
Nakamura Y
, Hamamoto R. The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene. Int J Cancer. 2012 Aug 01; 131(3):E179-89.
PMID:
22020899
.
Citations:
56
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kiyotani K, Mushiroda T, Tsunoda T, Morizono T, Hosono N, Kubo M, Tanigawara Y, Imamura CK, Flockhart DA, Aki F, Hirata K, Takatsuka Y, Okazaki M, Ohsumi S, Yamakawa T, Sasa M,
Nakamura Y
, Zembutsu H. A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese. Hum Mol Genet. 2012 Apr 01; 21(7):1665-72.
PMID:
22180457
.
Citations:
26
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Innocenti F, Owzar K, Cox NL, Evans P, Kubo M, Zembutsu H, Jiang C, Hollis D, Mushiroda T, Li L, Friedman P, Wang L, Glubb D, Hurwitz H, Giacomini KM, McLeod HL, Goldberg RM,
Schilsky RL
,
Kindler HL
,
Nakamura Y
,
Ratain MJ
. A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Clin Cancer Res. 2012 Jan 15; 18(2):577-84.
PMID:
22142827
; PMCID:
PMC3412624
.
Citations:
48
Fields:
Neo
Neoplasms
Translation:
Humans
Kumasaka N, Fujisawa H, Hosono N, Okada Y, Takahashi A,
Nakamura Y
, Kubo M, Kamatani N. PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data. Genet Epidemiol. 2011 Dec; 35(8):831-44.
PMID:
22125222
.
Citations:
7
Fields:
Epi
Epidemiology
Gen
Genetics
Translation:
Humans
Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, Lopez LM, Meacham S, Okada Y, Pirastu N, Sorice R, Teumer A, Voss K, Zhang W, Ramirez-Solis R, Bis JC, Ellinghaus D, Hottenga JJ, Langenberg C, Kovacs P, O'Reilly PF, Shin SY, Hartiala J, Kanoni S, Murgia F, Parsa A, Stephens J, van der Harst P, Ellen van der Schoot C, Allayee H, Attwood A, Balkau B, Basu S, Baumeister SE, Biino G, Bomba L, Chambers JC, Cucca F, D'Adamo P, Davies G, de Boer RA, de Geus EJ, Elliott P, Erdmann J, Evans DM, Falchi M, Feng W, Folsom AR, Frazer IH, Gibson QD, Glazer NL, Hammond C, Hartikainen AL, Heckbert SR, Hengstenberg C, Hersch M, Illig T, Loos RJ, Jolley J, Khaw KT, Kyrtsonis MC, Lagou V, Lloyd-Jones H, Lumley T, Mangino M, Maschio A, Mateo Leach I, McKnight B, Memari Y, Mitchell BD, Montgomery GW,
Nakamura Y
, Nauck M, Navis G, Nolte IM, Porteous DJ, Pouta A, Pramstaller PP, Pullat J, Ring SM, Rotter JI, Ruggiero D, Ruokonen A, Sala C, Samani NJ, Sambrook J, Schlessinger D, Schreiber S, Schunkert H, Scott J, Smith NL, Snieder H, Starr JM, Stumvoll M, Takahashi A, Tang WH, Taylor K, Tenesa A, Lay Thein S, Uda M, Ulivi S, van Veldhuisen DJ, Visscher PM, Wichmann HE, Wiggins KL, Willemsen G, Yang TP, Hua Zhao J, Zitting P, Bradley JR, Dedoussis GV, Gasparini P, Hazen SL, Metspalu A, Pirastu M, Shuldiner AR, Joost van Pelt L, Zwaginga JJ, Boomsma DI, Deary IJ, Franke A, Froguel P, Ganesh SK, Jarvelin MR, Martin NG, Meisinger C, Psaty BM, Spector TD, Wareham NJ, Akkerman JW, Ciullo M, Deloukas P, Greinacher A, Jupe S, Kamatani N, Khadake J, Kooner JS, Penninger J, Prokopenko I, Stemple D, Toniolo D, Wernisch L, Sanna S, Hicks AA, Rendon A, Ferreira MA, Ouwehand WH, Soranzo N, Gieger C, Mägi R, Gögele M, Esko T, Bastardot F, Bonnefond A, Cambien F, Döring A, Kühnel B, Nöthlings U, Tönjes A, Völker U. New gene functions in megakaryopoiesis and platelet formation. Nature. 2011 Nov 30; 480(7376):201-8.
PMID:
22139419
; PMCID:
PMC3335296
.
Citations:
216
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Ochi H, Hayes CN, Abe H, Hayashida Y, Uchiyama T, Kamatani N,
Nakamura Y
, Chayama K. Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C. J Infect Dis. 2012 Jan 15; 205(2):204-10.
PMID:
22124128
.
Citations:
7
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Yasuno K, Bakircioglu M, Low SK, Ruigrok YM, Hata A, Bijlenga P, Kasuya H, Krex D, Auburger G, Simon M, Krischek B, Ozturk AK, Mane S, Rinkel GJ, Steinmetz H, Hernesniemi J, Schaller K, Zembutsu H, Inoue I, Palotie A,
Nakamura Y
, Lifton RP, Bilgüvar K, Gaál E, Niemelä M, Jääskeläinen JE, Cambien F, Günel M. Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk. Proc Natl Acad Sci U S A. 2011 Dec 06; 108(49):19707-12.
PMID:
22106312
; PMCID:
PMC3241810
.
Citations:
52
Fields:
Sci
Science
Translation:
Humans
Cells
Hirota T, Saeki H, Tomita K, Tanaka S, Ebe K, Sakashita M, Yamada T, Fujieda S, Miyatake A, Doi S, Enomoto T, Hizawa N, Sakamoto T, Masuko H, Sasaki T, Ebihara T, Amagai M, Esaki H, Takeuchi S, Furue M, Noguchi E, Kamatani N,
Nakamura Y
, Kubo M, Tamari M. Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies. PLoS One. 2011; 6(11):e26987.
PMID:
22125604
; PMCID:
PMC3219642
.
Citations:
6
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Kiyotani K, Mushiroda T,
Nakamura Y
, Zembutsu H. Pharmacogenomics of tamoxifen: roles of drug metabolizing enzymes and transporters. Drug Metab Pharmacokinet. 2012; 27(1):122-31.
PMID:
22041137
.
Citations:
33
Fields:
Met
Metabolism
Pha
Pharmacology
Translation:
Humans
Ohshige T, Iwata M, Omori S, Tanaka Y, Hirose H, Kaku K, Maegawa H, Watada H, Kashiwagi A, Kawamori R, Tobe K, Kadowaki T,
Nakamura Y
, Maeda S. Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese. PLoS One. 2011; 6(10):e26911.
PMID:
22046406
; PMCID:
PMC3202571
.
Citations:
36
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Masuda K, Takano A, Oshita H, Akiyama H, Tsuchiya E, Kohno N,
Nakamura Y
, Daigo Y. Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer. Clin Cancer Res. 2011 Dec 15; 17(24):7712-22.
PMID:
22016508
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Nakamura Y
. Retracted: Modulation of p53?/Akt?/?phosphatase and tensin homolog expression by esculetin potentiates the anticancer activity of cisplatin and prevents its nephrotoxicity. Cancer Sci. 2012 Jan; 103(1):154.
PMID:
21895873
; PMCID:
PMC11164170
.
Citations:
Fields:
Neo
Neoplasms
Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga JJ, Kumar V, Lagou V, Liang L, Luan J, Vidal PM, Mateo Leach I, O'Reilly PF, Peden JF, Rahmioglu N, Soininen P, Speliotes EK, Yuan X, Thorleifsson G, Alizadeh BZ, Atwood LD, Borecki IB, Brown MJ, Charoen P, Cucca F, Das D, de Geus EJ, Dixon AL, Ehret G, Eyjolfsson GI, Farrall M, Forouhi NG, Friedrich N, Goessling W, Gudbjartsson DF, Harris TB, Hartikainen AL, Heath S, Hirschfield GM, Hofman A, Homuth G, Janssen HL, Johnson T, Kangas AJ, Kema IP, Lai S, Lathrop M, Lerch MM, Li Y, Liang TJ, Lin JP, Loos RJ, Martin NG, Moffatt MF, Montgomery GW, Munroe PB, Musunuru K,
Nakamura Y
, O'Donnell CJ, Olafsson I, Penninx BW, Pouta A, Prins BP, Prokopenko I, Puls R, Ruokonen A, Savolainen MJ, Schlessinger D, Schouten JN, Seedorf U, Sen-Chowdhry S, Siminovitch KA, Smit JH, Spector TD, Tan W, Teslovich TM, Tukiainen T, Uitterlinden AG, Van der Klauw MM, Vasan RS, Wallace C, Wallaschofski H, Wichmann HE, Willemsen G, Xu C, Yerges-Armstrong LM, Alcohol Genome-wide Association (AlcGen) Consortium, Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study, Genetic Investigation of Anthropometric Traits (GIANT) Consortium, Global Lipids Genetics Consortium, Genetics of Liver Disease (GOLD) Consortium, International Consortium for Blood Pressure (ICBP-GWAS), Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC), Abecasis GR, Ahmadi KR, Boomsma DI, Caulfield M, Cookson WO, van Duijn CM, Froguel P, Matsuda K, McCarthy MI, Meisinger C, Mooser V, Schumann G, Snieder H, Sternberg MJ, Stolk RP, Thomas HC, Thorsteinsdottir U, Uda M, Wareham NJ, Waterworth DM, Watkins H, Whitfield JB, Witteman JC, Wolffenbuttel BH, Fox CS, Ala-Korpela M, Stefansson K, Vollenweider P, Schadt EE, Scott J, Elliott P, Kooner JS, Kühnel B, Döring A, Hyppönen E, Kühn JP, Würtz P, Pietiläinen KH, Waeber G, Völzke H, Järvelin MR. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet. 2011 Oct 16; 43(11):1131-8.
PMID:
22001757
; PMCID:
PMC3482372
.
Citations:
299
Fields:
Gen
Genetics
Translation:
Humans
Nakamura Y
. Cancer vaccines. Clin Adv Hematol Oncol. 2011 Oct; 9(10):778-9.
PMID:
22252581
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Toyokawa G, Cho HS, Masuda K, Yamane Y, Yoshimatsu M, Hayami S, Takawa M, Iwai Y, Daigo Y, Tsuchiya E, Tsunoda T, Field HI, Kelly JD, Neal DE, Maehara Y, Ponder BA,
Nakamura Y
, Hamamoto R. Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway. Neoplasia. 2011 Oct; 13(10):887-98.
PMID:
22028615
; PMCID:
PMC3201566
.
Citations:
55
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Tantisira KG, Lasky-Su J, Harada M, Murphy A, Litonjua AA, Himes BE, Lange C, Lazarus R, Sylvia J, Klanderman B, Duan QL, Qiu W, Hirota T, Martinez FD, Mauger D, Sorkness C, Szefler S, Lazarus SC, Lemanske RF, Peters SP, Lima JJ,
Nakamura Y
, Tamari M, Weiss ST. Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med. 2011 Sep 29; 365(13):1173-83.
PMID:
21991891
; PMCID:
PMC3667396
.
Citations:
138
Fields:
Med
Medicine (General)
Translation:
Humans
Kiyotani K, Mushiroda T, Imamura CK, Tanigawara Y, Hosono N, Kubo M, Sasa M,
Nakamura Y
, Zembutsu H. Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients. Breast Cancer Res Treat. 2012 Jan; 131(1):137-45.
PMID:
21947681
.
Citations:
36
Fields:
Neo
Neoplasms
Translation:
Humans
Toyokawa G, Cho HS, Iwai Y, Yoshimatsu M, Takawa M, Hayami S, Maejima K, Shimizu N, Tanaka H, Tsunoda T, Field HI, Kelly JD, Neal DE, Ponder BA, Maehara Y,
Nakamura Y
, Hamamoto R. The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6. Cancer Prev Res (Phila). 2011 Dec; 4(12):2051-61.
PMID:
21930796
.
Citations:
41
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Arakawa S, Takahashi A, Ashikawa K, Hosono N, Aoi T, Yasuda M, Oshima Y, Yoshida S, Enaida H, Tsuchihashi T, Mori K, Honda S, Negi A, Arakawa A, Kadonosono K, Kiyohara Y, Kamatani N,
Nakamura Y
, Ishibashi T, Kubo M. Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population. Nat Genet. 2011 Sep 11; 43(10):1001-4.
PMID:
21909106
.
Citations:
73
Fields:
Gen
Genetics
Translation:
Humans
Cells
Nakabayashi K, Tajima A, Yamamoto K, Takahashi A, Hata K, Takashima Y, Koyanagi M, Nakaoka H, Akamizu T, Ishikawa N, Kubota S, Maeda S, Tsunoda T, Kubo M, Kamatani N,
Nakamura Y
, Sasazuki T, Shirasawa S. Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. J Hum Genet. 2011 Nov; 56(11):772-8.
PMID:
21900946
.
Citations:
17
Fields:
Gen
Genetics
Translation:
Humans
Maimbo M, Kiyotani K, Mushiroda T, Masimirembwa C,
Nakamura Y
. CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans. Eur J Clin Pharmacol. 2012 Mar; 68(3):267-71.
PMID:
21901344
.
Citations:
22
Fields:
Dru
Drug Therapy
Pha
Pharmacology
Translation:
Humans
CT
Clinical Trials
Abe H, Hayes CN, Ochi H, Tsuge M, Miki D, Hiraga N, Imamura M, Takahashi S, Kubo M,
Nakamura Y
, Kamatani N, Chayama K. Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state. J Med Virol. 2011 Sep; 83(9):1597-607.
PMID:
21739451
.
Citations:
12
Fields:
Vir
Virology
Translation:
Humans
Cells
Srinivasan Y, Sasa M, Honda J, Takahashi A, Uno S, Kamatani N, Kubo M,
Nakamura Y
, Zembutsu H. Genome-wide association study of epirubicin-induced leukopenia in Japanese patients. Pharmacogenet Genomics. 2011 Sep; 21(9):552-8.
PMID:
21799462
.
Citations:
6
Fields:
Gen
Genetics
Pha
Pharmacology
Translation:
Humans
Goetz MP, Schaid DJ, Wickerham DL, Safgren S, Mushiroda T, Kubo M, Batzler A, Costantino JP, Vogel VG, Paik S, Carlson EE, Flockhart DA, Wolmark N,
Nakamura Y
, Weinshilboum RM, Ingle JN, Ames MM. Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials. Clin Cancer Res. 2011 Nov 01; 17(21):6944-51.
PMID:
21880792
; PMCID:
PMC3207003
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Li J, Yang D, He Y, Wang M, Wen Z, Liu L, Yao J, Matsuda K,
Nakamura Y
, Yu J, Jiang X, Sun S, Liu Q, Jiang X, Song Q, Chen M, Yang H, Tang F, Hu X, Wang J, Chang Y, He X, Chen Y, Lin J. Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study. PLoS One. 2011; 6(8):e24221.
PMID:
21904616
; PMCID:
PMC3164164
.
Citations:
29
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Nishino R, Takano A, Oshita H, Ishikawa N, Akiyama H, Ito H, Nakayama H, Miyagi Y, Tsuchiya E, Kohno N,
Nakamura Y
, Daigo Y. Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer. Clin Cancer Res. 2011 Oct 01; 17(19):6272-86.
PMID:
21849417
.
Citations:
39
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Aragaki M, Takahashi K, Akiyama H, Tsuchiya E, Kondo S,
Nakamura Y
, Daigo Y. Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer. Clin Cancer Res. 2011 Sep 15; 17(18):5889-900.
PMID:
21813631
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Hiraga N, Abe H, Imamura M, Tsuge M, Takahashi S, Hayes CN, Ochi H, Tateno C, Yoshizato K,
Nakamura Y
, Kamatani N, Chayama K. Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus. Hepatology. 2011 Sep 02; 54(3):764-71.
PMID:
21618576
.
Citations:
11
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Chantarangsu S, Mushiroda T, Mahasirimongkol S, Kiertiburanakul S, Sungkanuparph S, Manosuthi W, Tantisiriwat W, Charoenyingwattana A, Sura T, Takahashi A, Kubo M, Kamatani N, Chantratita W,
Nakamura Y
. Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash. Clin Infect Dis. 2011 Aug; 53(4):341-8.
PMID:
21810746
.
Citations:
32
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Cho HS, Kelly JD, Hayami S, Toyokawa G, Takawa M, Yoshimatsu M, Tsunoda T, Field HI, Neal DE, Ponder BA,
Nakamura Y
, Hamamoto R. Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1. Neoplasia. 2011 Aug; 13(8):676-84.
PMID:
21847359
; PMCID:
PMC3156658
.
Citations:
64
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Doi S, Fujita K, Miyatake A, Enomoto T, Miyagawa T, Adachi M, Tanaka H, Niimi A, Matsumoto H, Ito I, Masuko H, Sakamoto T, Hizawa N, Taniguchi M, Lima JJ, Irvin CG, Peters SP, Himes BE, Litonjua AA, Tantisira KG, Weiss ST, Kamatani N,
Nakamura Y
, Tamari M. Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. Nat Genet. 2011 Jul 31; 43(9):893-6.
PMID:
21804548
; PMCID:
PMC4310726
.
Citations:
161
Fields:
Gen
Genetics
Translation:
Humans
Cells
Noguchi E, Sakamoto H, Hirota T, Ochiai K, Imoto Y, Sakashita M, Kurosaka F, Akasawa A, Yoshihara S, Kanno N, Yamada Y, Shimojo N, Kohno Y, Suzuki Y, Kang MJ, Kwon JW, Hong SJ, Inoue K, Goto Y, Yamashita F, Asada T, Hirose H, Saito I, Fujieda S, Hizawa N, Sakamoto T, Masuko H,
Nakamura Y
, Nomura I, Tamari M, Arinami T, Yoshida T, Saito H, Matsumoto K. Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations. PLoS Genet. 2011 Jul; 7(7):e1002170.
PMID:
21814517
; PMCID:
PMC3140987
.
Citations:
61
Fields:
Gen
Genetics
Translation:
Humans
Okada Y, Yamazaki K, Umeno J, Takahashi A, Kumasaka N, Ashikawa K, Aoi T, Takazoe M, Matsui T, Hirano A, Matsumoto T, Kamatani N,
Nakamura Y
, Yamamoto K, Kubo M. HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease. Gastroenterology. 2011 Sep; 141(3):864-871.e1-5.
PMID:
21699788
.
Citations:
46
Fields:
Gas
Gastroenterology
Translation:
Humans
Mbarek H, Ochi H, Urabe Y, Kumar V, Kubo M, Hosono N, Takahashi A, Kamatani Y, Miki D, Abe H, Tsunoda T, Kamatani N, Chayama K,
Nakamura Y
, Matsuda K. A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. Hum Mol Genet. 2011 Oct 01; 20(19):3884-92.
PMID:
21750111
.
Citations:
105
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Satou M,
Nakamura Y
, Ando H, Sugimoto H. Understanding the functional significance of ghrelin processing and degradation. Peptides. 2011 Nov; 32(11):2183-90.
PMID:
21763742
.
Citations:
5
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Akuta N, Suzuki F, Hirakawa M, Kawamura Y, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Chayama K,
Nakamura Y
, Kumada H. Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy. Intervirology. 2012; 55(3):231-41.
PMID:
21734353
.
Citations:
10
Fields:
Vir
Virology
Translation:
Humans
Miki D, Ochi H, Hayes CN, Abe H, Yoshima T, Aikata H, Ikeda K, Kumada H, Toyota J, Morizono T, Tsunoda T, Kubo M,
Nakamura Y
, Kamatani N, Chayama K. Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers. Nat Genet. 2011 Jul 03; 43(8):797-800.
PMID:
21725309
.
Citations:
75
Fields:
Gen
Genetics
Translation:
Humans
Cells
Barratt BJ, Mushiroda T, Takahashi A, Jawaid A, Hada S, Umemura T, Fukuoka M, Nakata K, Ohe Y, Kato H, Kudoh S, March R,
Nakamura Y
, Kamatani N, Nyberg F. Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data. Pharmacogenomics. 2011 Jul; 12(7):965-75.
PMID:
21787189
.
Citations:
4
Fields:
Gen
Genetics
Pha
Pharmacology
Translation:
Humans
Chayama K, Hayes CN, Abe H, Miki D, Ochi H, Karino Y, Toyota J,
Nakamura Y
, Kamatani N, Sezaki H, Kobayashi M, Akuta N, Suzuki F, Kumada H. IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C. J Infect Dis. 2011 Jul 01; 204(1):84-93.
PMID:
21628662
; PMCID:
PMC3307155
.
Citations:
45
Fields:
Com
Communicable Diseases
Translation:
Humans
Okada Y, Hirota T, Kamatani Y, Takahashi A, Ohmiya H, Kumasaka N, Higasa K, Yamaguchi-Kabata Y, Hosono N, Nalls MA, Chen MH, van Rooij FJ, Smith AV, Tanaka T, Couper DJ, Zakai NA, Ferrucci L, Longo DL, Hernandez DG, Witteman JC, Harris TB, O'Donnell CJ, Ganesh SK, Matsuda K, Tsunoda T, Tanaka T, Kubo M,
Nakamura Y
, Tamari M, Yamamoto K, Kamatani N. Identification of nine novel loci associated with white blood cell subtypes in a Japanese population. PLoS Genet. 2011 Jun; 7(6):e1002067.
PMID:
21738478
; PMCID:
PMC3128095
.
Citations:
51
Fields:
Gen
Genetics
Translation:
Humans
Cells
Reiner AP, Lettre G, Nalls MA, Ganesh SK, Mathias R, Austin MA, Dean E, Arepalli S, Britton A, Chen Z, Couper D, Curb JD, Eaton CB, Fornage M, Grant SF, Harris TB, Hernandez D, Kamatini N, Keating BJ, Kubo M, LaCroix A, Lange LA, Liu S, Lohman K, Meng Y, Mohler ER, Musani S,
Nakamura Y
, O'Donnell CJ, Okada Y, Palmer CD, Papanicolaou GJ, Patel KV, Singleton AB, Takahashi A, Tang H, Taylor HA, Taylor K, Thomson C, Yanek LR, Yang L, Ziv E, Zonderman AB, Folsom AR, Evans MK, Liu Y, Becker DM, Snively BM, Wilson JG. Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). PLoS Genet. 2011 Jun; 7(6):e1002108.
PMID:
21738479
; PMCID:
PMC3128101
.
Citations:
97
Fields:
Gen
Genetics
Translation:
Humans
Cells
Nalls MA, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Toniolo D, Zakai NA, Yang Q, Greinacher A, Wood AR, Garcia M, Gasparini P, Liu Y, Lumley T, Folsom AR, Reiner AP, Gieger C, Lagou V, Felix JF, Gouskova NA, Biffi A, Chong S, Wiggins KL, Rendon A, Dehghan A, Moore M, Taylor K, Wilson JG, Lettre G, Hofman A, Bis JC, Pirastu N, Fox CS, Meisinger C, Sambrook J, Arepalli S, Nauck M, Prokisch H, Stephens J, Glazer NL, Cupples LA, Okada Y, Takahashi A, Kamatani Y, Matsuda K, Tsunoda T, Tanaka T, Kubo M,
Nakamura Y
, Yamamoto K, Kamatani N, Stumvoll M, Prokopenko I, Illig T, Patel KV, Garner SF, Kuhnel B, Mangino M, Oostra BA, Thein SL, Coresh J, Wichmann HE, Menzel S, Lin J, Pistis G, Spector TD, Teumer A, Eiriksdottir G, Gudnason V, Bandinelli S, Frayling TM, Chakravarti A, van Duijn CM, Melzer D, Ouwehand WH, Levy D, Boerwinkle E, Singleton AB, Hernandez DG, Longo DL, Soranzo N, Witteman JC, Psaty BM, Ferrucci L, Harris TB, O'Donnell CJ, Ganesh SK, Völzke H, Döring A, Völker U, Tönjes A, Uitterlinden AG. Multiple loci are associated with white blood cell phenotypes. PLoS Genet. 2011 Jun; 7(6):e1002113.
PMID:
21738480
; PMCID:
PMC3128114
.
Citations:
79
Fields:
Gen
Genetics
Translation:
Humans
Cells
Iida A, Takahashi A, Kubo M, Saito S, Hosono N, Ohnishi Y, Kiyotani K, Mushiroda T, Nakajima M, Ozaki K, Tanaka T, Tsunoda T, Oshima S, Sano M, Kamei T, Tokuda T, Aoki M, Hasegawa K, Mizoguchi K, Morita M, Takahashi Y, Katsuno M, Atsuta N, Watanabe H, Tanaka F, Kaji R, Nakano I, Kamatani N, Tsuji S, Sobue G,
Nakamura Y
, Ikegawa S. A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese. Hum Mol Genet. 2011 Sep 15; 20(18):3684-92.
PMID:
21665992
.
Citations:
24
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Yamaguchi K, Sakai M, Kim J, Tsunesumi S, Fujii T, Ikenoue T, Yamada Y, Akiyama Y, Muto Y, Yamaguchi R, Miyano S,
Nakamura Y
, Furukawa Y. MRG-binding protein contributes to colorectal cancer development. Cancer Sci. 2011 Aug; 102(8):1486-92.
PMID:
21535316
; PMCID:
PMC11159092
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Akaza H, Tsukamoto T, Fujioka T, Tomita Y, Kitamura T, Ozono S, Miki T, Naito S, Zembutsu H,
Nakamura Y
. Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level. Jpn J Clin Oncol. 2011 Aug; 41(8):1023-30.
PMID:
21642665
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Hashimoto Y, Ochi H, Abe H, Hayashida Y, Tsuge M, Mitsui F, Hiraga N, Imamura M, Takahashi S, Nelson Hayes C, Ohishi W, Kubo M, Tsunoda T, Kamatani N,
Nakamura Y
, Chayama K. Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b. J Med Virol. 2011 Jun; 83(6):981-8.
PMID:
21503910
.
Citations:
6
Fields:
Vir
Virology
Translation:
Humans
Cells
Azakami T, Hayes CN, Sezaki H, Kobayashi M, Akuta N, Suzuki F, Kumada H, Abe H, Miki D, Tsuge M, Imamura M, Kawakami Y, Takahashi S, Ochi H,
Nakamura Y
, Kamatani N, Chayama K. Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy. J Med Virol. 2011 Jun; 83(6):1048-57.
PMID:
21503919
.
Citations:
16
Fields:
Vir
Virology
Translation:
Humans
Cells
Nakamura Y
. Retraction. Cloning and expression of soluble recombinant human esophageal cancer-related gene 4 protein and its inhibitory effect on tumor growth in vitro and in vivo in esophageal carcinoma. Cancer Sci. 2011 Jun; 102(6):1245.
PMID:
21338439
; PMCID:
PMC11158166
.
Citations:
2
Fields:
Neo
Neoplasms
Mushiroda T,
Nakamura Y
. Personalizing carbamazepine therapy. Genome Med. 2011 May 30; 3(5):28.
PMID:
21635710
; PMCID:
PMC3219069
.
Citations:
Fields:
Gen
Genetics
Toyokawa G, Masuda K, Daigo Y, Cho HS, Yoshimatsu M, Takawa M, Hayami S, Maejima K, Chino M, Field HI, Neal DE, Tsuchiya E, Ponder BA, Maehara Y,
Nakamura Y
, Hamamoto R. Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer. Mol Cancer. 2011 May 28; 10:65.
PMID:
21619671
; PMCID:
PMC3125391
.
Citations:
61
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Takawa M, Masuda K, Kunizaki M, Daigo Y, Takagi K, Iwai Y, Cho HS, Toyokawa G, Yamane Y, Maejima K, Field HI, Kobayashi T, Akasu T, Sugiyama M, Tsuchiya E, Atomi Y, Ponder BA,
Nakamura Y
, Hamamoto R. Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker. Cancer Sci. 2011 Jul; 102(7):1298-305.
PMID:
21539681
; PMCID:
PMC11159278
.
Citations:
91
Fields:
Neo
Neoplasms
Translation:
Humans
Tanabe T, Yamaguchi N, Matsuda K, Yamazaki K, Takahashi S, Tojo A, Onizuka M, Eishi Y, Akiyama H, Ishikawa J, Mori T, Hara M, Koike K, Kawa K, Kawase T, Morishima Y, Amano H, Kobayashi-Miura M, Kakamu T,
Nakamura Y
, Asano S, Fujita Y. Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population. Int J Hematol. 2011 Jun; 93(6):771-778.
PMID:
21573891
.
Citations:
10
Fields:
Hem
Hematology
Translation:
Humans
Cells
Kou I, Takahashi A, Urano T, Fukui N, Ito H, Ozaki K, Tanaka T, Hosoi T, Shiraki M, Inoue S,
Nakamura Y
, Kamatani N, Kubo M, Mori S, Ikegawa S. Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese. PLoS One. 2011 May 06; 6(5):e19641.
PMID:
21573128
; PMCID:
PMC3089633
.
Citations:
16
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Terao C, Yamada R, Ohmura K, Takahashi M, Kawaguchi T, Kochi Y, Human Disease Genomics Working Group, RA Clinical and Genetic Study Consortium, Okada Y,
Nakamura Y
, Yamamoto K, Melchers I, Lathrop M, Mimori T, Matsuda F. The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. Hum Mol Genet. 2011 Jul 01; 20(13):2680-5.
PMID:
21505073
.
Citations:
53
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Kumar V, Kato N, Urabe Y, Takahashi A, Muroyama R, Hosono N, Otsuka M, Tateishi R, Omata M, Nakagawa H, Koike K, Kamatani N, Kubo M,
Nakamura Y
, Matsuda K. Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma. Nat Genet. 2011 May; 43(5):455-8.
PMID:
21499248
.
Citations:
168
Fields:
Gen
Genetics
Translation:
Humans
Cells
Ueda K, Saichi N, Takami S, Kang D, Toyama A, Daigo Y, Ishikawa N, Kohno N, Tamura K, Shuin T, Nakayama M, Sato TA,
Nakamura Y
, Nakagawa H. A comprehensive peptidome profiling technology for the identification of early detection biomarkers for lung adenocarcinoma. PLoS One. 2011 Apr 12; 6(4):e18567.
PMID:
21533267
; PMCID:
PMC3075260
.
Citations:
13
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Toyama A, Nakagawa H, Matsuda K, Ishikawa N, Kohno N, Daigo Y, Sato TA,
Nakamura Y
, Ueda K. Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer. Proteome Sci. 2011 Apr 08; 9:18.
PMID:
21473792
; PMCID:
PMC3090313
.
Citations:
8
Kumar V, Matsuo K, Takahashi A, Hosono N, Tsunoda T, Kamatani N, Kong SY, Nakagawa H, Cui R, Tanikawa C, Seto M, Morishima Y, Kubo M,
Nakamura Y
, Matsuda K. Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility. J Hum Genet. 2011 Jun; 56(6):436-9.
PMID:
21471979
.
Citations:
15
Fields:
Gen
Genetics
Translation:
Humans
Cells
Cha PC, Takahashi A, Hosono N, Low SK, Kamatani N, Kubo M,
Nakamura Y
. A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids. Nat Genet. 2011 May; 43(5):447-50.
PMID:
21460842
.
Citations:
66
Fields:
Gen
Genetics
Translation:
Humans
Cells
Park JH, Katagiri T, Chung S, Kijima K,
Nakamura Y
. Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin. Neoplasia. 2011 Apr; 13(4):320-6.
PMID:
21472136
; PMCID:
PMC3071080
.
Citations:
53
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Okamoto K, Tokunaga K, Doi K, Fujita T, Suzuki H, Katoh T, Watanabe T, Nishida N, Mabuchi A, Takahashi A, Kubo M, Maeda S,
Nakamura Y
, Noiri E. Common variation in GPC5 is associated with acquired nephrotic syndrome. Nat Genet. 2011 May; 43(5):459-63.
PMID:
21441931
.
Citations:
50
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Johnson TA, Niimura Y, Tanaka H,
Nakamura Y
, Tsunoda T. hzAnalyzer: detection, quantification, and visualization of contiguous homozygosity in high-density genotyping datasets. Genome Biol. 2011; 12(3):R21.
PMID:
21396103
; PMCID:
PMC3129671
.
Citations:
1
Fields:
Gen
Genetics
Translation:
Humans
Cells
Umeno J, Asano K, Matsushita T, Matsumoto T, Kiyohara Y, Iida M,
Nakamura Y
, Kamatani N, Kubo M. Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis. Inflamm Bowel Dis. 2011 Dec; 17(12):2407-15.
PMID:
21351207
.
Citations:
58
Fields:
Gas
Gastroenterology
Translation:
Humans
Maeda S, Koya D, Araki SI, Babazono T, Umezono T, Toyoda M, Kawai K, Imanishi M, Uzu T, Suzuki D, Maegawa H, Kashiwagi A, Iwamoto Y,
Nakamura Y
. Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes. Clin Exp Nephrol. 2011 Jun; 15(3):381-390.
PMID:
21331741
; PMCID:
PMC3110272
.
Citations:
41
Fields:
Nep
Nephrology
Translation:
Humans
Tomita Y, Imai K, Senju S, Irie A, Inoue M, Hayashida Y, Shiraishi K, Mori T, Daigo Y, Tsunoda T, Ito T, Nomori H,
Nakamura Y
, Kohrogi H, Nishimura Y. A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells. Cancer Sci. 2011 Apr; 102(4):697-705.
PMID:
21231984
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Abe H, Hayes CN, Ochi H, Maekawa T, Tsuge M, Miki D, Mitsui F, Hiraga N, Imamura M, Takahashi S, Kubo M,
Nakamura Y
, Chayama K. IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy. J Hepatol. 2011 Jun; 54(6):1094-101.
PMID:
21145800
.
Citations:
39
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Iida A, Takahashi A, Deng M, Zhang Y, Wang J, Atsuta N, Tanaka F, Kamei T, Sano M, Oshima S, Tokuda T, Morita M, Akimoto C, Nakajima M, Kubo M, Kamatani N, Nakano I, Sobue G,
Nakamura Y
, Fan D, Ikegawa S. Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians. Neurobiol Aging. 2011 Apr; 32(4):757.e13-4.
PMID:
21295378
.
Citations:
8
Fields:
Ger
Geriatrics
Neu
Neurology
Phy
Physiology
Translation:
Humans
Cells
Zembutsu H, Sasa M, Kiyotani K, Mushiroda T,
Nakamura Y
. Should CYP2D6 inhibitors be administered in conjunction with tamoxifen? Expert Rev Anticancer Ther. 2011 Feb; 11(2):185-93.
PMID:
21342038
.
Citations:
4
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Yoshimatsu M, Toyokawa G, Hayami S, Unoki M, Tsunoda T, Field HI, Kelly JD, Neal DE, Maehara Y, Ponder BA,
Nakamura Y
, Hamamoto R. Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers. Int J Cancer. 2011 Feb 01; 128(3):562-73.
PMID:
20473859
.
Citations:
151
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hayami S, Kelly JD, Cho HS, Yoshimatsu M, Unoki M, Tsunoda T, Field HI, Neal DE, Yamaue H, Ponder BA,
Nakamura Y
, Hamamoto R. Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. Int J Cancer. 2011 Feb 01; 128(3):574-86.
PMID:
20333681
.
Citations:
224
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Suzuki F, Suzuki Y, Akuta N, Sezaki H, Hirakawa M, Kawamura Y, Hosaka T, Kobayashi M, Saito S, Arase Y, Ikeda K, Kobayashi M, Chayama K, Kamatani N,
Nakamura Y
, Miyakawa Y, Kumada H. Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir. Hepatology. 2011 Feb; 53(2):415-21.
PMID:
21246582
.
Citations:
29
Fields:
Gas
Gastroenterology
Translation:
Humans
Low SK, Zembutsu H, Takahashi A, Kamatani N, Cha PC, Hosono N, Kubo M, Matsuda K,
Nakamura Y
. Impact of LIMK1, MMP2 and TNF-a variations for intracranial aneurysm in Japanese population. J Hum Genet. 2011 Mar; 56(3):211-6.
PMID:
21228795
.
Citations:
17
Fields:
Gen
Genetics
Translation:
Humans
Ochi H, Maekawa T, Abe H, Hayashida Y, Nakano R, Imamura M, Hiraga N, Kawakami Y, Aimitsu S, Kao JH, Kubo M, Tsunoda T, Kumada H,
Nakamura Y
, Hayes CN, Chayama K. IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations. J Gen Virol. 2011 May; 92(Pt 5):1071-1081.
PMID:
21228123
.
Citations:
26
Fields:
Vir
Virology
Translation:
Humans
Cells
Iida A, Hosono N, Sano M, Kamei T, Oshima S, Tokuda T, Kubo M,
Nakamura Y
, Ikegawa S. Optineurin mutations in Japanese amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 2012 Feb; 83(2):233-5.
PMID:
21217154
.
Citations:
13
Fields:
Neu
Neurology
Neu
Neurosurgery
Psy
Psychiatry
Translation:
Humans
Chung S, Nakashima M, Zembutsu H,
Nakamura Y
. Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production. Proc Jpn Acad Ser B Phys Biol Sci. 2011; 87(8):563-73.
PMID:
21986318
; PMCID:
PMC3313695
.
Citations:
18
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Cells
Piao L, Nakagawa H, Ueda K, Chung S, Kashiwaya K, Eguchi H, Ohigashi H, Ishikawa O, Daigo Y, Matsuda K,
Nakamura Y
. C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage. Genes Chromosomes Cancer. 2011 Jan; 50(1):13-24.
PMID:
20931645
.
Citations:
23
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Okada Y, Takahashi A, Ohmiya H, Kumasaka N, Kamatani Y, Hosono N, Tsunoda T, Matsuda K, Tanaka T, Kubo M,
Nakamura Y
, Yamamoto K, Kamatani N. Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus. Hum Mol Genet. 2011 Mar 15; 20(6):1224-31.
PMID:
21196492
.
Citations:
45
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Nakamura Y
. Retraction: Curcumin targets Akt cell survival signaling pathway in HTLV-I-infected T-cell lines. Cancer Sci. 2011 Feb; 102(2):498.
PMID:
21265953
.
Citations:
1
Fields:
Neo
Neoplasms
Nakamura Y
. Retraction: Epstein-Barr virus-encoded latent membrane protein 1 activates ß-catenin signaling in B lymphocytes. Cancer Sci. 2011 Feb; 102(2):500.
PMID:
21265955
.
Citations:
Fields:
Neo
Neoplasms
Nakamura Y
. Retraction: Anti-adult T-cell leukemia effects of a novel synthetic retinoid, Am80 (Tamibarotene). Cancer Sci. 2011 Feb; 102(2):499.
PMID:
21265954
.
Citations:
Fields:
Neo
Neoplasms
Nishimoto K, Ikari K, Kaneko H, Tsukahara S, Kochi Y, Yamamoto K,
Nakamura Y
, Toyama Y, Taniguchi A, Yamanaka H, Momohara S. Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population. J Rheumatol. 2011 Feb; 38(2):221-8.
PMID:
21159824
.
Citations:
3
Fields:
Rhe
Rheumatology
Translation:
Humans
Ozeki T, Mushiroda T, Yowang A, Takahashi A, Kubo M, Shirakata Y, Ikezawa Z, Iijima M, Shiohara T, Hashimoto K, Kamatani N,
Nakamura Y
. Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population. Hum Mol Genet. 2011 Mar 01; 20(5):1034-41.
PMID:
21149285
.
Citations:
164
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Isono H, Gyoda Y, Yoshizawa A, Kenmoku T,
Nakamura Y
, Onose A, Kawabata M, Iwase S. [A case with an ovarian cancer patient who could receive anti-cancer therapy and palliative care simultaneously at home through seamless collaboration in healthcare linkage]. Gan To Kagaku Ryoho. 2010 Dec; 37 Suppl 2:253-5.
PMID:
21368541
.
Citations:
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Kato Y, Zembutsu H, Takata R, Miya F, Tsunoda T, Obara W, Fujioka T,
Nakamura Y
. Predicting response of bladder cancers to gemcitabine and carboplatin neoadjuvant chemotherapy through genome-wide gene expression profiling. Exp Ther Med. 2011 Jan; 2(1):47-56.
PMID:
22977468
; PMCID:
PMC3440662
.
Citations:
8
Cho HS, Suzuki T, Dohmae N, Hayami S, Unoki M, Yoshimatsu M, Toyokawa G, Takawa M, Chen T, Kurash JK, Field HI, Ponder BA,
Nakamura Y
, Hamamoto R. Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells. Cancer Res. 2011 Feb 01; 71(3):655-60.
PMID:
21115810
.
Citations:
98
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells