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Ralf Kittler

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InstitutionUniversity of Chicago
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Blandin AF, Giglio R, Graham MS, Garcia G, Malinowski S, Woods JK, Ramkissoon S, Ramkissoon L, Dubois F, Schoolcraft K, Tsai J, Wang D, Jones R, Vogelzang J, Pelton K, Becker S, Watkinson F, Sinai C, Cohen EF, Booker MA, Tolstorukov MY, Haemels V, Goumnerova L, Wright K, Kieran M, Fehnel K, Reardon D, Tauziede-Espariat A, Lulla R, Carcamo B, Chaleff S, Charest A, De Smet F, Ligon AH, Dubuc A, Pages M, Varlet P, Wen PY, Alexander BM, Chi S, Alexandrescu S, Kittler R, Bachoo R, Bandopadhayay P, Beroukhim R, Ligon KL. ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma. Clin Cancer Res. 2023 Jul 14; 29(14):2651-2667. PMID: 36780194; PMCID: PMC10363218.
      Citations: 2     Fields:    Translation:Animals
    2. Huffman KE, Li LS, Carstens R, Park H, Girard L, Avila K, Wei S, Kollipara R, Timmons B, Sudderth J, Bendris N, Kim J, Villalobos P, Fujimoto J, Schmid S, Deberardinis RJ, Wistuba I, Heymach J, Kittler R, Akbay EA, Posner B, Wang Y, Lam S, Kliewer SA, Mangelsdorf DJ, Minna JD. Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers. Front Oncol. 2023; 13:1025443. PMID: 37035141; PMCID: PMC10078807.
      Citations: 2     
    3. Bhattacharyya S, Kollipara RK, Orquera-Tornakian G, Goetsch S, Zhang M, Perry C, Li B, Shelton JM, Bhakta M, Duan J, Xie Y, Xiao G, Evers BM, Hon GC, Kittler R, Munshi NV. Global chromatin landscapes identify candidate noncoding modifiers of cardiac rhythm. J Clin Invest. 2023 02 01; 133(3). PMID: 36454649; PMCID: PMC9888383.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    4. Wang S, Huo X, Yang Y, Mo Y, Kollipara RK, Kittler R. Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma. Cancer Lett. 2023 01 01; 552:215984. PMID: 36330954.
      Citations: 1     Fields:    Translation:HumansCells
    5. Gu G, Tian L, Herzog SK, Rechoum Y, Gelsomino L, Gao M, Du L, Kim JA, Dustin D, Lo HC, Beyer AR, Edwards DG, Gonzalez T, Tsimelzon A, Huang HJ, Fernandez NM, Grimm SL, Hilsenbeck SG, Liu D, Xu J, Alaniz A, Li S, Mills GB, Janku F, Kittler R, Zhang XH, Coarfa C, Foulds CE, Symmans WF, Fuqua SAW, Andò S. Correction to: Hormonal modulation of ESR1 mutant metastasis. Oncogene. 2022 Jan; 41(3):460. PMID: 34782721.
      Citations:    Fields:    
    6. Yenerall P, Kittler R, Minna J. Structure-based classification of EGFR mutations informs inhibitor selection for lung cancer therapy. Cancer Cell. 2021 11 08; 39(11):1455-1457. PMID: 34752753; PMCID: PMC9241337.
      Citations: 1     Fields:    Translation:Humans
    7. Fletcher-Sananikone E, Kanji S, Tomimatsu N, Kollipara RK, Saha D, Floyd JR, Sung P, Hromas R, Burns TC, Kittler R, Habib AA, Mukherjee B, Burma S, Di Cristofaro LFM. Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence. Cancer Res. 2021 12 01; 81(23):5935-5947. PMID: 34580063; PMCID: PMC9724593.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    8. Yenerall P, Kollipara RK, Avila K, Peyton M, Eide CA, Bottomly D, McWeeney SK, Liu Y, Westover KD, Druker BJ, Minna JD, Kittler R. Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations. Cancer Res. 2021 09 15; 81(18):4685-4695. PMID: 34301758; PMCID: PMC8448967.
      Citations: 4     Fields:    Translation:HumansCells
    9. Servetto A, Kollipara R, Formisano L, Lin CC, Lee KM, Sudhan DR, Gonzalez-Ericsson PI, Chatterjee S, Mendiratta S, Akamatsu H, James N, Bianco R, Hanker AB, Kittler R, Arteaga CL, Guerrero-Zotano A. Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER+ Breast Cancer. Clin Cancer Res. 2021 08 01; 27(15):4379-4396. PMID: 34011560; PMCID: PMC8338892.
      Citations: 19     Fields:    Translation:HumansCells
    10. Gu G, Tian L, Herzog SK, Rechoum Y, Gelsomino L, Gao M, Du L, Kim JA, Dustin D, Lo HC, Beyer AR, Edwards DG, Gonzalez T, Tsimelzon A, Huang HJ, Fernandez NM, Grimm SL, Hilsenbeck SG, Liu D, Xu J, Alaniz A, Li S, Mills GB, Janku F, Kittler R, Zhang XH, Coarfa C, Foulds CE, Symmans WF, Fuqua SAW, Andò S. Hormonal modulation of ESR1 mutant metastasis. Oncogene. 2021 02; 40(5):997-1011. PMID: 33323970; PMCID: PMC8020875.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    11. Gilbreath C, Ma S, Yu L, Sonavane R, Roggero CM, Devineni A, Mauck R, Desai NB, Bagrodia A, Kittler R, Raj GV, Yin Y. Dynamic differences between DNA damage repair responses in primary tumors and cell lines. Transl Oncol. 2021 Jan; 14(1):100898. PMID: 33096336; PMCID: PMC7576517.
      Citations: 1     
    12. Wang S, Gilbreath C, Kollipara RK, Sonavane R, Huo X, Yenerall P, Das A, Ma S, Raj GV, Kittler R. Mithramycin suppresses DNA damage repair via targeting androgen receptor in prostate cancer. Cancer Lett. 2020 09 28; 488:40-49. PMID: 32485222; PMCID: PMC7370677.
      Citations: 3     Fields:    Translation:HumansCells
    13. Hight SK, Mootz A, Kollipara RK, McMillan E, Yenerall P, Otaki Y, Li LS, Avila K, Peyton M, Rodriguez-Canales J, Mino B, Villalobos P, Girard L, Dospoy P, Larsen J, White MA, Heymach JV, Wistuba II, Kittler R, Minna JD. An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis. Neoplasia. 2020 08; 22(8):294-310. PMID: 32512502; PMCID: PMC7281309.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    14. Yenerall P, Das AK, Wang S, Kollipara RK, Li LS, Villalobos P, Flaming J, Lin YF, Huffman K, Timmons BC, Gilbreath C, Sonavane R, Kinch LN, Rodriguez-Canales J, Moran C, Behrens C, Hirasawa M, Takata T, Murakami R, Iwanaga K, Chen BPC, Grishin NV, Raj GV, Wistuba II, Minna JD, Kittler R. RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer. Cell Chem Biol. 2020 01 16; 27(1):105-121.e14. PMID: 31883965; PMCID: PMC8048778.
      Citations: 23     Fields:    Translation:HumansCells
    15. Bhargava V, Goldstein CD, Russell L, Xu L, Ahmed M, Li W, Casey A, Servage K, Kollipara R, Picciarelli Z, Kittler R, Yatsenko A, Carmell M, Orth K, Amatruda JF, Yanowitz JL, Buszczak M. GCNA Preserves Genome Integrity and Fertility Across Species. Dev Cell. 2020 01 06; 52(1):38-52.e10. PMID: 31839537; PMCID: PMC6946843.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    16. Todorova PK, Fletcher-Sananikone E, Mukherjee B, Kollipara R, Vemireddy V, Xie XJ, Guida PM, Story MD, Hatanpaa K, Habib AA, Kittler R, Bachoo R, Hromas R, Floyd JR, Burma S. Radiation-Induced DNA Damage Cooperates with Heterozygosity of TP53 and PTEN to Generate High-Grade Gliomas. Cancer Res. 2019 07 15; 79(14):3749-3761. PMID: 31088835; PMCID: PMC6635038.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    17. Katafuchi T, Holland WL, Kollipara RK, Kittler R, Mangelsdorf DJ, Kliewer SA. PPAR?-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice. Proc Natl Acad Sci U S A. 2018 11 27; 115(48):12102-12111. PMID: 30420515; PMCID: PMC6275522.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    18. Wang S, Ekoue DN, Raj GV, Kittler R. Targeting the turnover of oncoproteins as a new avenue for therapeutics development in castration-resistant prostate cancer. Cancer Lett. 2018 12 01; 438:86-96. PMID: 30217566; PMCID: PMC6186492.
      Citations:    Fields:    Translation:Humans
    19. Cornforth MN, Anur P, Wang N, Robinson E, Ray FA, Bedford JS, Loucas BD, Williams ES, Peto M, Spellman P, Kollipara R, Kittler R, Gray JW, Bailey SM. Molecular Cytogenetics Guides Massively Parallel Sequencing of a Radiation-Induced Chromosome Translocation in Human Cells. Radiat Res. 2018 07; 190(1):88-97. PMID: 29749794; PMCID: PMC6055522.
      Citations: 3     Fields:    Translation:HumansCells
    20. Kittler R, Shiang C, Hutchinson R, Kollipara RK, Kapur P, Franto F, Lotan Y. Grade progression in urothelial carcinoma can occur with high or low mutational homology: a first-step toward tumor-specific care in initial low-grade bladder cancer. Oncotarget. 2018 Feb 06; 9(10):9415-9424. PMID: 29507699; PMCID: PMC5823658.
      Citations: 1     Fields:    
    21. Luo J, Attard G, Balk SP, Bevan C, Burnstein K, Cato L, Cherkasov A, De Bono JS, Dong Y, Gao AC, Gleave M, Heemers H, Kanayama M, Kittler R, Lang JM, Lee RJ, Logothetis CJ, Matusik R, Plymate S, Sawyers CL, Selth LA, Soule H, Tilley W, Weigel NL, Zoubeidi A, Dehm SM, Raj GV. Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting. Eur Urol. 2018 05; 73(5):715-723. PMID: 29258679; PMCID: PMC5929166.
      Citations: 63     Fields:    Translation:Humans
    22. Lan Q, Cao M, Kollipara RK, Rosa JB, Kittler R, Jiang H. FoxA transcription factor Fork head maintains the intestinal stem/progenitor cell identities in Drosophila. Dev Biol. 2018 01 15; 433(2):324-343. PMID: 29108672.
      Citations: 5     Fields:    Translation:AnimalsCells
    23. Dalvi MP, Wang L, Zhong R, Kollipara RK, Park H, Bayo J, Yenerall P, Zhou Y, Timmons BC, Rodriguez-Canales J, Behrens C, Mino B, Villalobos P, Parra ER, Suraokar M, Pataer A, Swisher SG, Kalhor N, Bhanu NV, Garcia BA, Heymach JV, Coombes K, Xie Y, Girard L, Gazdar AF, Kittler R, Wistuba II, Minna JD, Martinez ED. Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors. Cell Rep. 2017 05 23; 19(8):1669-1684. PMID: 28538184; PMCID: PMC5531293.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    24. Ahmad Z, Xing C, Panach K, Kittler R, McPhaul MJ, Wilson JD. Identification of the Underlying Androgen Receptor Defect in the Dallas Reifenstein Family. J Endocr Soc. 2017 Jul 01; 1(7):836-842. PMID: 29264534; PMCID: PMC5686667.
      Citations:    
    25. Eskiocak B, McMillan EA, Mendiratta S, Kollipara RK, Zhang H, Humphries CG, Wang C, Garcia-Rodriguez J, Ding M, Zaman A, Rosales TI, Eskiocak U, Smith MP, Sudderth J, Komurov K, Deberardinis RJ, Wellbrock C, Davies MA, Wargo JA, Yu Y, De Brabander JK, Williams NS, Chin L, Rizos H, Long GV, Kittler R, White MA. Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma. Cancer Discov. 2017 08; 7(8):832-851. PMID: 28455392; PMCID: PMC5540806.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    26. Stricker TP, Brown CD, Bandlamudi C, McNerney M, Kittler R, Montoya V, Peterson A, Grossman R, White KP. Robust stratification of breast cancer subtypes using differential patterns of transcript isoform expression. PLoS Genet. 2017 03; 13(3):e1006589. PMID: 28263985; PMCID: PMC5367891.
      Citations: 36     Fields:    Translation:HumansCells
    27. Singh DK, Kollipara RK, Vemireddy V, Yang XL, Sun Y, Regmi N, Klingler S, Hatanpaa KJ, Raisanen J, Cho SK, Sirasanagandla S, Nannepaga S, Piccirillo S, Mashimo T, Wang S, Humphries CG, Mickey B, Maher EA, Zheng H, Kim RS, Kittler R, Bachoo RM. Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma. Cell Rep. 2017 01 24; 18(4):961-976. PMID: 28122245; PMCID: PMC5321610.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    28. Wang S, Kollipara RK, Humphries CG, Ma SH, Hutchinson R, Li R, Siddiqui J, Tomlins SA, Raj GV, Kittler R. The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer. Oncotarget. 2016 Oct 04; 7(40):64921-64931. PMID: 27626314; PMCID: PMC5323126.
      Citations: 20     Fields:    Translation:HumansCells
    29. Liu H, Liang C, Kollipara RK, Matsui M, Ke X, Jeong BC, Wang Z, Yoo KS, Yadav GP, Kinch LN, Grishin NV, Nam Y, Corey DR, Kittler R, Liu Q. HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing. Mol Cell. 2016 08 04; 63(3):420-32. PMID: 27425409; PMCID: PMC4975613.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    30. Thu KL, Papari-Zareei M, Stastny V, Song K, Peyton M, Martinez VD, Zhang YA, Castro IB, Varella-Garcia M, Liang H, Xing C, Kittler R, Milchgrub S, Castrillon DH, Davidson HL, Reynolds CP, Lam WL, Lea J, Gazdar AF. A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas. Oncotarget. 2017 Aug 01; 8(31):50489-50499. PMID: 28881577; PMCID: PMC5584155.
      Citations: 16     Fields:    
    31. Thu KL, Papari-Zareei M, Stastny V, Song K, Peyton M, Martinez VD, Zhang YA, Castro IB, Varella-Garcia M, Liang H, Xing C, Kittler R, Milchgrub S, Castrillon DH, Davidson HL, Reynolds CP, Lam WL, Lea J, Gazdar AF. A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas. Oncotarget. 2016 Jun 10. PMID: 27302921.
      Citations:    
    32. Yenerall P, Kittler R. Minireview: Familiar Faces in Unfamiliar Places: The Emerging Role of Nuclear Receptors in Lung Cancer. Mol Endocrinol. 2015 Dec; 29(12):1675-83. PMID: 26484581; PMCID: PMC5414662.
      Citations: 2     Fields:    Translation:HumansAnimals
    33. Kim H, Rodriguez-Navas C, Kollipara RK, Kapur P, Pedrosa I, Brugarolas J, Kittler R, Ye J. Unsaturated Fatty Acids Stimulate Tumor Growth through Stabilization of ß-Catenin. Cell Rep. 2015 Oct 20; 13(3):495-503. PMID: 26456834; PMCID: PMC4618234.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    34. Mootha VV, Hussain I, Cunnusamy K, Graham E, Gong X, Neelam S, Xing C, Kittler R, Petroll WM. TCF4 Triplet Repeat Expansion and Nuclear RNA Foci in Fuchs' Endothelial Corneal Dystrophy. Invest Ophthalmol Vis Sci. 2015 Feb 26; 56(3):2003-11. PMID: 25722209; PMCID: PMC4373545.
      Citations: 50     Fields:    Translation:HumansCells
    35. Yenerall P, Kittler R. Harnessing the nuclear receptor PPAR? to inhibit the growth of lung adenocarcinoma by rewiring metabolic circuitries. Mol Cell Oncol. 2015 Apr-Jun; 2(2):e980660. PMID: 27308443; PMCID: PMC4905022.
      Citations: 1     
    36. Kollipara RK, Kittler R. An integrated functional genomic analysis identifies the antitumorigenic mechanism of action for PPAR? in lung cancer cells. Genom Data. 2015 Mar; 3:80-6. PMID: 26484153; PMCID: PMC4535999.
      Citations: 2     
    37. Srivastava N, Kollipara RK, Singh DK, Sudderth J, Hu Z, Nguyen H, Wang S, Humphries CG, Carstens R, Huffman KE, DeBerardinis RJ, Kittler R. Inhibition of cancer cell proliferation by PPAR? is mediated by a metabolic switch that increases reactive oxygen species levels. Cell Metab. 2014 Oct 07; 20(4):650-61. PMID: 25264247; PMCID: PMC4191999.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    38. Yun EJ, Baek ST, Xie D, Tseng SF, Dobin T, Hernandez E, Zhou J, Zhang L, Yang J, Sun H, Xiao G, He D, Kittler R, Hsieh JT. DAB2IP regulates cancer stem cell phenotypes through modulating stem cell factor receptor and ZEB1. Oncogene. 2015 May 21; 34(21):2741-52. PMID: 25043300.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    39. Eliazer S, Palacios V, Wang Z, Kollipara RK, Kittler R, Buszczak M. Lsd1 restricts the number of germline stem cells by regulating multiple targets in escort cells. PLoS Genet. 2014 Mar; 10(3):e1004200. PMID: 24625679; PMCID: PMC3952827.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    40. Wang S, Kollipara RK, Srivastava N, Li R, Ravindranathan P, Hernandez E, Freeman E, Humphries CG, Kapur P, Lotan Y, Fazli L, Gleave ME, Plymate SR, Raj GV, Hsieh JT, Kittler R. Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer. Proc Natl Acad Sci U S A. 2014 Mar 18; 111(11):4251-6. PMID: 24591637; PMCID: PMC3964108.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    41. Kappei D, Butter F, Benda C, Scheibe M, Stevense M, Novo CL, Basquin C, Araki M, Araki K, Krastev DB, Kittler R, Jessberger R, Mann M, Buchholz F, Draškovic I, Londoño-Vallejo JA. HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. EMBO J. 2013 Jun 12; 32(12):1681-701. PMID: 23685356; PMCID: PMC3680732.
      Citations: 39     Fields:    Translation:HumansCells
    42. Kittler R, Zhou J, Hua S, Ma L, Liu Y, Pendleton E, Cheng C, Gerstein M, White KP. A comprehensive nuclear receptor network for breast cancer cells. Cell Rep. 2013 Feb 21; 3(2):538-51. PMID: 23375374.
      Citations: 51     Fields:    Translation:HumansCells
    43. Park J, Sarode VR, Euhus D, Kittler R, Scherer PE. Neuregulin 1-HER axis as a key mediator of hyperglycemic memory effects in breast cancer. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):21058-63. PMID: 23213231; PMCID: PMC3529089.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    44. Ludwig MZ, Kittler R, White KP, Kreitman M. Consequences of eukaryotic enhancer architecture for gene expression dynamics, development, and fitness. PLoS Genet. 2011 Nov; 7(11):e1002364. PMID: 22102826; PMCID: PMC3213169.
      Citations: 42     Fields:    Translation:AnimalsCells
    45. Sun C, Southard C, Witonsky DB, Kittler R, Di Rienzo A. Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations. PLoS Genet. 2010 Oct 28; 6(10):e1001178. PMID: 21060808; PMCID: PMC2965758.
      Citations: 9     Fields:    Translation:HumansCells
    46. Hua S, Kittler R, White KP. Genomic antagonism between retinoic acid and estrogen signaling in breast cancer. Cell. 2009 Jun 26; 137(7):1259-71. PMID: 19563758; PMCID: PMC3374131.
      Citations: 160     Fields:    Translation:HumansCells
    47. Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, Tagliaferro A, Poser I, Hutchins JR, Pinchev D, Buchholz F, Peters JM, Hyman AA, Gingras AC, Pelletier L, Hegemann B. HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr Biol. 2009 May 26; 19(10):816-26. PMID: 19427217.
      Citations: 137     Fields:    Translation:HumansAnimalsCells
    48. Theis M, Slabicki M, Junqueira M, Paszkowski-Rogacz M, Sontheimer J, Kittler R, Heninger AK, Glatter T, Kruusmaa K, Poser I, Hyman AA, Pisabarro MT, Gstaiger M, Aebersold R, Shevchenko A, Buchholz F. Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division. EMBO J. 2009 May 20; 28(10):1453-65. PMID: 19387489; PMCID: PMC2684023.
      Citations: 59     Fields:    Translation:HumansCells
    49. Ding L, Paszkowski-Rogacz M, Nitzsche A, Slabicki MM, Heninger AK, de Vries I, Kittler R, Junqueira M, Shevchenko A, Schulz H, Hubner N, Doss MX, Sachinidis A, Hescheler J, Iacone R, Anastassiadis K, Stewart AF, Pisabarro MT, Caldarelli A, Poser I, Theis M, Buchholz F. A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell. 2009 May 08; 4(5):403-15. PMID: 19345177.
      Citations: 151     Fields:    Translation:AnimalsCells
    50. Kittler R, Pelletier L, Buchholz F. Systems biology of mammalian cell division. Cell Cycle. 2008 Jul 15; 7(14):2123-8. PMID: 18635956.
      Citations: 5     Fields:    Translation:HumansAnimals
    51. Poser I, Sarov M, Hutchins JR, Toyoda Y, Pozniakovsky A, Weigl D, Nitzsche A, Bird AW, Pelletier L, Kittler R, Hua S, Naumann R, Augsburg M, Sykora MM, Hofemeister H, Zhang Y, Nasmyth K, White KP, Dietzel S, Mechtler K, Durbin R, Stewart AF, Peters JM, Buchholz F, Hyman AA, Hériché JK, Hegemann B. BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nat Methods. 2008 May; 5(5):409-15. PMID: 18391959; PMCID: PMC2871289.
      Citations: 311     Fields:    Translation:AnimalsCells
    52. Zhu F, Lawo S, Bird A, Pinchev D, Ralph A, Richter C, Kittler R, Hyman AA, Pelletier L, Müller-Reichert T. The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis. Curr Biol. 2008 Jan 22; 18(2):136-41. PMID: 18207742.
      Citations: 99     Fields:    Translation:HumansCells
    53. Kittler R, Pelletier L, Heninger AK, Slabicki M, Theis M, Miroslaw L, Poser I, Lawo S, Grabner H, Kozak K, Wagner J, Surendranath V, Richter C, Bowen W, Jackson AL, Habermann B, Hyman AA, Buchholz F. Genome-scale RNAi profiling of cell division in human tissue culture cells. Nat Cell Biol. 2007 Dec; 9(12):1401-12. PMID: 17994010.
      Citations: 172     Fields:    Translation:HumansCells
    54. Kittler R, Surendranath V, Heninger AK, Slabicki M, Theis M, Putz G, Franke K, Caldarelli A, Grabner H, Kozak K, Wagner J, Rees E, Korn B, Frenzel C, Sachse C, Guo J, Schelter J, Burchard J, Linsley PS, Jackson AL, Habermann B, Buchholz F, Sönnichsen B. Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies. Nat Methods. 2007 Apr; 4(4):337-44. PMID: 17351622.
      Citations: 94     Fields:    Translation:HumansAnimalsCells
    55. Buchholz F, Kittler R, Slabicki M, Theis M. Enzymatically prepared RNAi libraries. Nat Methods. 2006 Sep; 3(9):696-700. PMID: 16929314.
      Citations: 22     Fields:    Translation:HumansAnimals
    56. Quinque D, Kittler R, Kayser M, Stoneking M, Nasidze I. Evaluation of saliva as a source of human DNA for population and association studies. Anal Biochem. 2006 Jun 15; 353(2):272-7. PMID: 16620753.
      Citations: 72     Fields:    Translation:HumansCells
    57. Kittler R, Heninger AK, Franke K, Habermann B, Buchholz F. Production of endoribonuclease-prepared short interfering RNAs for gene silencing in mammalian cells. Nat Methods. 2005 Oct; 2(10):779-84. PMID: 16179925.
      Citations: 46     Fields:    Translation:HumansCells
    58. Kittler R, Buchholz F. Functional genomic analysis of cell division by endoribonuclease-prepared siRNAs. Cell Cycle. 2005 Apr; 4(4):564-7. PMID: 15876870.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    59. Kittler R, Pelletier L, Ma C, Poser I, Fischer S, Hyman AA, Buchholz F. RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells. Proc Natl Acad Sci U S A. 2005 Feb 15; 102(7):2396-401. PMID: 15695330; PMCID: PMC548992.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    60. Kittler R, Putz G, Pelletier L, Poser I, Heninger AK, Drechsel D, Fischer S, Konstantinova I, Habermann B, Grabner H, Yaspo ML, Himmelbauer H, Korn B, Neugebauer K, Pisabarro MT, Buchholz F. An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division. Nature. 2004 Dec 23; 432(7020):1036-40. PMID: 15616564.
      Citations: 183     Fields:    Translation:HumansCells
    61. Kayser M, Kittler R, Erler A, Hedman M, Lee AC, Mohyuddin A, Mehdi SQ, Stoneking M, Jobling MA, Sajantila A, Tyler-Smith C, Rosser Z. A comprehensive survey of human Y-chromosomal microsatellites. Am J Hum Genet. 2004 Jun; 74(6):1183-97. PMID: 15195656; PMCID: PMC1182082.
      Citations: 57     Fields:    Translation:HumansCells
    62. Kittler R, Buchholz F, Windisch MP, Pietschmann T, Bartenschlager R, Frese M, Krönke J. Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. J Virol. 2004 Apr; 78(7):3436-46. PMID: 15016866; PMCID: PMC371081.
      Citations: 62     Fields:    Translation:HumansCells
    63. Calegari F, Marzesco AM, Kittler R, Buchholz F, Huttner WB. Tissue-specific RNA interference in post-implantation mouse embryos using directional electroporation and whole embryo culture. Differentiation. 2004 Mar; 72(2-3):92-102. PMID: 15066189.
      Citations: 12     Fields:    Translation:Animals
    64. Kittler R, Kayser M, Stoneking M. Molecular evolution of Pediculus humanus and the origin of clothing. Curr Biol. 2003 Aug 19; 13(16):1414-7. PMID: 12932325.
      Citations: 65     Fields:    Translation:HumansAnimals
    65. Kittler R, Buchholz F. RNA interference: gene silencing in the fast lane. Semin Cancer Biol. 2003 Aug; 13(4):259-65. PMID: 14563120.
      Citations: 4     Fields:    Translation:HumansAnimals
    66. Kittler R, Erler A, Brauer S, Stoneking M, Kayser M. Apparent intrachromosomal exchange on the human Y chromosome explained by population history. Eur J Hum Genet. 2003 Apr; 11(4):304-14. PMID: 12700604.
      Citations: 16     Fields:    Translation:HumansCells
    67. Kittler R, Stoneking M, Kayser M. A whole genome amplification method to generate long fragments from low quantities of genomic DNA. Anal Biochem. 2002 Jan 15; 300(2):237-44. PMID: 11779116.
      Citations: 9     Fields:    Translation:HumansCells
    68. Arntz R, Emde C, Heitz J, Kittler R, Schäfer JH. [The effect of ceftriaxone on the blood coagulation parameters of intensive care patients]. Wien Med Wochenschr Suppl. 1985; 87:16-21. PMID: 3856971.
      Citations:    Fields:    Translation:Humans
    69. Fritschka E, Gotzen R, Kittler R, Schöneshöfer M. Effect of metoprolol on 24-hour urinary excretion of adrenal steroids and kallikrein in patients with essential hypertension. Br J Pharmacol. 1984 Feb; 81(2):245-53. PMID: 6367871; PMCID: PMC1986883.
      Citations: 1     Fields:    Translation:Humans
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