Loading...
The University of Chicago Header Logo
Keywords
Last Name
Institution

Lucia Schuger

TitlePROFESSOR
InstitutionUniversity of Chicago
DepartmentPathology
AddressChicago IL 60637
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Duan FF, Barron G, Meliton A, Mutlu GM, Dulin NO, Schuger L. P311 Promotes Lung Fibrosis via Stimulation of Transforming Growth Factor-ß1, -ß2, and -ß3 Translation. Am J Respir Cell Mol Biol. 2019 02; 60(2):221-231. PMID: 30230348.
      View in: PubMed
    2. Kouhkheil R, Fridoni M, Piryaei A, Taheri S, Chirani AS, Anarkooli IJ, Nejatbakhsh R, Shafikhani S, Schuger LA, Reddy VB, Ghoreishi SK, Jalalifirouzkouhi R, Chien S, Bayat M. The effect of combined pulsed wave low-level laser therapy and mesenchymal stem cell-conditioned medium on the healing of an infected wound with methicillin-resistant Staphylococcal aureus in diabetic rats. J Cell Biochem. 2018 07; 119(7):5788-5797. PMID: 29574990.
      View in: PubMed
    3. Soleimani H, Amini A, Taheri S, Sajadi E, Shafikhani S, Schuger LA, Reddy VB, Ghoreishi SK, Pouriran R, Chien S, Bayat M. The effect of combined photobiomodulation and curcumin on skin wound healing in type I diabetes in rats. J Photochem Photobiol B. 2018 Apr; 181:23-30. PMID: 29486459.
      View in: PubMed
    4. Cheng T, Yue M, Aslam MN, Wang X, Shekhawat G, Varani J, Schuger L. Neuronal Protein 3.1 Deficiency Leads to Reduced Cutaneous Scar Collagen Deposition and Tensile Strength due to Impaired Transforming Growth Factor-ß1 to -ß3 Translation. Am J Pathol. 2017 Feb; 187(2):292-303. PMID: 27939132.
      View in: PubMed
    5. Yue M, Pacheco G, Cheng T, Li J, Wang Y, Henske EP, Schuger L. Evidence Supporting a Lymphatic Endothelium Origin for Angiomyolipoma, a TSC2(-) Tumor Related to Lymphangioleiomyomatosis. Am J Pathol. 2016 07; 186(7):1825-1836. PMID: 27289491.
      View in: PubMed
    6. Yue MM, Lv K, Meredith SC, Martindale JL, Gorospe M, Schuger L. Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor ß1-3 (TGF-ß1-3). J Biol Chem. 2014 Dec 05; 289(49):33971-83. PMID: 25336651.
      View in: PubMed
    7. Gao L, Yue MM, Davis J, Hyjek E, Schuger L. In pulmonary lymphangioleiomyomatosis expression of progesterone receptor is frequently higher than that of estrogen receptor. Virchows Arch. 2014 Apr; 464(4):495-503. PMID: 24570392.
      View in: PubMed
    8. Badri KR, Yue M, Carretero OA, Aramgam SL, Cao J, Sharkady S, Kim GH, Taylor GA, Byron KL, Schuger L. Blood pressure homeostasis is maintained by a P311-TGF-ß axis. J Clin Invest. 2013 Oct; 123(10):4502-12. PMID: 24091331.
      View in: PubMed
    9. Davis JM, Hyjek E, Husain AN, Shen L, Jones J, Schuger LA. Lymphatic endothelial differentiation in pulmonary lymphangioleiomyomatosis cells. J Histochem Cytochem. 2013 Aug; 61(8):580-90. PMID: 23609227.
      View in: PubMed
    10. Badri KR, Gao L, Hyjek E, Schuger N, Schuger L, Qin W, Chekaluk Y, Kwiatkowski DJ, Zhe X. Exonic mutations of TSC2/TSC1 are common but not seen in all sporadic pulmonary lymphangioleiomyomatosis. Am J Respir Crit Care Med. 2013 Mar 15; 187(6):663-5. PMID: 23504366.
      View in: PubMed
    11. Badri KR, Zhou Y, Dhru U, Aramgam S, Schuger L. Effects of the SANT domain of tension-induced/inhibited proteins (TIPs), novel partners of the histone acetyltransferase p300, on p300 activity and TIP-6-induced adipogenesis. Mol Cell Biol. 2008 Oct; 28(20):6358-72. PMID: 18710950.
      View in: PubMed
    12. Cho JA, Osenkowski P, Zhao H, Kim S, Toth M, Cole K, Aboukameel A, Saliganan A, Schuger L, Bonfil RD, Fridman R. The inactive 44-kDa processed form of membrane type 1 matrix metalloproteinase (MT1-MMP) enhances proteolytic activity via regulation of endocytosis of active MT1-MMP. J Biol Chem. 2008 Jun 20; 283(25):17391-405. PMID: 18413312.
      View in: PubMed
    13. Badri KR, Zhou Y, Schuger L. Embryological origin of airway smooth muscle. Proc Am Thorac Soc. 2008 Jan 01; 5(1):4-10. PMID: 18094078.
      View in: PubMed
    14. Shi J, Badri KR, Choudhury R, Schuger L. P311-induced myofibroblasts exhibit ameboid-like migration through RalA activation. Exp Cell Res. 2006 Oct 15; 312(17):3432-42. PMID: 16934802.
      View in: PubMed
    15. Jakkaraju S, Zhe X, Pan D, Choudhury R, Schuger L. TIPs are tension-responsive proteins involved in myogenic versus adipogenic differentiation. Dev Cell. 2005 Jul; 9(1):39-49. PMID: 15992539.
      View in: PubMed
    16. Zhe X, Schuger L. Combined smooth muscle and melanocytic differentiation in lymphangioleiomyomatosis. J Histochem Cytochem. 2004 Dec; 52(12):1537-42. PMID: 15557209.
      View in: PubMed
    17. Zhe X, Yang Y, Schuger L. Imbalanced plasminogen system in lymphangioleiomyomatosis: potential role of serum response factor. Am J Respir Cell Mol Biol. 2005 Jan; 32(1):28-34. PMID: 15514113.
      View in: PubMed
    18. Varani J, Schuger L, Dame MK, Leonard C, Fligiel SE, Kang S, Fisher GJ, Voorhees JJ. Reduced fibroblast interaction with intact collagen as a mechanism for depressed collagen synthesis in photodamaged skin. J Invest Dermatol. 2004 Jun; 122(6):1471-9. PMID: 15175039.
      View in: PubMed
    19. Paliwal S, Shi J, Dhru U, Zhou Y, Schuger L. P311 binds to the latency associated protein and downregulates the expression of TGF-beta1 and TGF-beta2. Biochem Biophys Res Commun. 2004 Mar 19; 315(4):1104-9. PMID: 14985127.
      View in: PubMed
    20. Ustach CV, Taube ME, Hurst NJ, Bhagat S, Bonfil RD, Cher ML, Schuger L, Kim HR. A potential oncogenic activity of platelet-derived growth factor d in prostate cancer progression. Cancer Res. 2004 Mar 01; 64(5):1722-9. PMID: 14996732.
      View in: PubMed
    21. Jakkaraju S, Zhe X, Schuger L. Role of stretch in activation of smooth muscle cell lineage. Trends Cardiovasc Med. 2003 Nov; 13(8):330-5. PMID: 14596949.
      View in: PubMed
    22. Ji YH, Weiss L, Zeira M, Abdul-Hai A, Reich S, Schuger L, Slavin S. Allogeneic cell-mediated immunotherapy of leukemia with immune donor lymphocytes to upregulate antitumor effects and downregulate antihost responses. Bone Marrow Transplant. 2003 Sep; 32(5):495-504. PMID: 12942096.
      View in: PubMed
    23. Yang Y, Zhe X, Phan SH, Ullenbruch M, Schuger L. Involvement of serum response factor isoforms in myofibroblast differentiation during bleomycin-induced lung injury. Am J Respir Cell Mol Biol. 2003 Nov; 29(5):583-90. PMID: 12777247.
      View in: PubMed
    24. Zhe X, Yang Y, Jakkaraju S, Schuger L. Tissue inhibitor of metalloproteinase-3 downregulation in lymphangioleiomyomatosis: potential consequence of abnormal serum response factor expression. Am J Respir Cell Mol Biol. 2003 Apr; 28(4):504-11. PMID: 12654640.
      View in: PubMed
    25. Pan D, Zhe X, Jakkaraju S, Taylor GA, Schuger L. P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype. J Clin Invest. 2002 Nov; 110(9):1349-58. PMID: 12417574.
      View in: PubMed
    26. Demayo F, Minoo P, Plopper CG, Schuger L, Shannon J, Torday JS. Mesenchymal-epithelial interactions in lung development and repair: are modeling and remodeling the same process? Am J Physiol Lung Cell Mol Physiol. 2002 Sep; 283(3):L510-7. PMID: 12169568.
      View in: PubMed
    27. Beqaj S, Jakkaraju S, Mattingly RR, Pan D, Schuger L. High RhoA activity maintains the undifferentiated mesenchymal cell phenotype, whereas RhoA down-regulation by laminin-2 induces smooth muscle myogenesis. J Cell Biol. 2002 Mar 04; 156(5):893-903. PMID: 11877460.
      View in: PubMed
    28. Waghray A, Keppler D, Sloane BF, Schuger L, Chen YQ. Analysis of a truncated form of cathepsin H in human prostate tumor cells. J Biol Chem. 2002 Mar 29; 277(13):11533-8. PMID: 11796715.
      View in: PubMed
    29. Panigrahi S, Yacovlev E, Gelfand Y, Schuger L, Slavin S, Morecki S. Intraportal and systemic allogeneic cell therapy in a murine model of hepatic metastatic breast cancer. Cytokines Cell Mol Ther. 2002; 7(3):99-106. PMID: 12850809.
      View in: PubMed
    30. Reddy KB, McGowen R, Schuger L, Visscher D, Sheng S. Maspin expression inversely correlates with breast tumor progression in MMTV/TGF-alpha transgenic mouse model. Oncogene. 2001 Oct 04; 20(45):6538-43. PMID: 11641778.
      View in: PubMed
    31. Liu J, Beqaj S, Yang Y, Honoré B, Schuger L. Heterogeneous nuclear ribonucleoprotein-H plays a suppressive role in visceral myogenesis. Mech Dev. 2001 Jun; 104(1-2):79-87. PMID: 11404082.
      View in: PubMed
    32. Yang Y, Beqaj S, Kemp P, Ariel I, Schuger L. Stretch-induced alternative splicing of serum response factor promotes bronchial myogenesis and is defective in lung hypoplasia. J Clin Invest. 2000 Dec; 106(11):1321-30. PMID: 11104785.
      View in: PubMed
    33. Qureshi F, Yang Y, Jaques SM, Johnson MP, Naparstek Y, Ulmansky R, Schuger L. Anti-DNA antibodies cross-reacting with laminin inhibit trophoblast attachment and migration: implications for recurrent pregnancy loss in SLE patients. Am J Reprod Immunol. 2000 Sep; 44(3):136-42. PMID: 11028899.
      View in: PubMed
    34. Relan NK, Yang Y, Beqaj S, Miner JH, Schuger L. Cell elongation induces laminin alpha2 chain expression in mouse embryonic mesenchymal cells: role in visceral myogenesis. J Cell Biol. 1999 Dec 13; 147(6):1341-50. PMID: 10601345.
      View in: PubMed
    35. Zhang J, O'Shea S, Liu J, Schuger L. Bronchial smooth muscle hypoplasia in mouse embryonic lungs exposed to a laminin beta1 chain antisense oligonucleotide. Mech Dev. 1999 Dec; 89(1-2):15-23. PMID: 10559476.
      View in: PubMed
    36. Yang Y, Relan NK, Przywara DA, Schuger L. Embryonic mesenchymal cells share the potential for smooth muscle differentiation: myogenesis is controlled by the cell's shape. Development. 1999 Jul; 126(13):3027-33. PMID: 10357945.
      View in: PubMed
    37. Varani J, Dame MK, Wojno K, Schuger L, Johnson KJ. Characteristics of nonmalignant and malignant human prostate in organ culture. Lab Invest. 1999 Jun; 79(6):723-31. PMID: 10378515.
      View in: PubMed
    38. Relan NK, Schuger L. Basement membranes in development. Pediatr Dev Pathol. 1999 Mar-Apr; 2(2):103-18. PMID: 9949216.
      View in: PubMed
    39. Yang Y, Palmer KC, Relan N, Diglio C, Schuger L. Role of laminin polymerization at the epithelial mesenchymal interface in bronchial myogenesis. Development. 1998 Jul; 125(14):2621-9. PMID: 9636077.
      View in: PubMed
    40. Schuger L, Yurchenco P, Relan NK, Yang Y. Laminin fragment E4 inhibition studies: basement membrane assembly and embryonic lung epithelial cell polarization requires laminin polymerization. Int J Dev Biol. 1998 Mar; 42(2):217-20. PMID: 9551867.
      View in: PubMed
    41. Backenroth R, Schuger L, Wald H, Popovtzer MM. Glycerol-induced acute renal failure attenuates subsequent HgCl2-associated nephrotoxicity: correlation of renal function and morphology. Ren Fail. 1998 Jan; 20(1):15-26. PMID: 9509557.
      View in: PubMed
    42. Schuger L, Skubitz AP, Zhang J, Sorokin L, He L. Laminin alpha1 chain synthesis in the mouse developing lung: requirement for epithelial-mesenchymal contact and possible role in bronchial smooth muscle development. J Cell Biol. 1997 Oct 20; 139(2):553-62. PMID: 9334356.
      View in: PubMed
    43. Schuger L. Laminins in lung development. Exp Lung Res. 1997 Mar-Apr; 23(2):119-29. PMID: 9088922.
      View in: PubMed
    44. Schuger L, Skubitz AP, Gilbride K, Mandel R, He L. Laminin and heparan sulfate proteoglycan mediate epithelial cell polarization in organotypic cultures of embryonic lung cells: evidence implicating involvement of the inner globular region of laminin beta 1 chain and the heparan sulfate groups of heparan sulfate proteoglycan. Dev Biol. 1996 Oct 10; 179(1):264-73. PMID: 8873769.
      View in: PubMed
    45. Schuger L, Johnson GR, Gilbride K, Plowman GD, Mandel R. Amphiregulin in lung branching morphogenesis: interaction with heparan sulfate proteoglycan modulates cell proliferation. Development. 1996 Jun; 122(6):1759-67. PMID: 8674415.
      View in: PubMed
    46. Schuger L, Skubitz AP, de las Morenas A, Gilbride K. Two separate domains of laminin promote lung organogenesis by different mechanisms of action. Dev Biol. 1995 Jun; 169(2):520-32. PMID: 7781896.
      View in: PubMed
    47. Schuger L, Varani J, Mitra R, Gilbride K. Retinoic acid stimulates mouse lung development by a mechanism involving epithelial-mesenchymal interaction and regulation of epidermal growth factor receptors. Dev Biol. 1993 Oct; 159(2):462-73. PMID: 8405671.
      View in: PubMed
    48. Varani J, Fligiel SE, Schuger L, Perone P, Inman D, Griffiths CE, Voorhees JJ. Effects of all-trans retinoic acid and Ca++ on human skin in organ culture. Am J Pathol. 1993 Jan; 142(1):189-98. PMID: 8424454.
      View in: PubMed
    49. Schuger L, Varani J, Killen PD, Skubitz AP, Gilbride K. Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells. Dev Dyn. 1992 Sep; 195(1):43-54. PMID: 1292752.
      View in: PubMed
    50. Schuger L, Skubitz AP, O'Shea KS, Chang JF, Varani J. Identification of laminin domains involved in branching morphogenesis: effects of anti-laminin monoclonal antibodies on mouse embryonic lung development. Dev Biol. 1991 Aug; 146(2):531-41. PMID: 1907584.
      View in: PubMed
    51. Varani J, Stoolman L, Wang T, Schuger L, Flippen C, Dame M, Johnson KJ, Todd RF, Ryan US, Ward PA. Thrombospondin production and thrombospondin-mediated adhesion in U937 cells. Exp Cell Res. 1991 Jul; 195(1):177-82. PMID: 2055266.
      View in: PubMed
    52. Varani J, Schuger L, Fligiel SE, Inman DR, Chakrabarty S. Production of fibronectin by human tumor cells and interaction with exogenous fibronectin: comparison of cell lines obtained from colon adenocarcinomas and squamous carcinomas of the upper aerodigestive tract. Int J Cancer. 1991 Feb 01; 47(3):421-5. PMID: 1993550.
      View in: PubMed
    53. Schuger L, O'Shea KS, Nelson BB, Varani J. Organotypic arrangement of mouse embryonic lung cells on a basement membrane extract: involvement of laminin. Development. 1990 Dec; 110(4):1091-9. PMID: 2100256.
      View in: PubMed
    54. Naparstek Y, Ben-Yehuda A, Madaio MP, Bar-Tana R, Schuger L, Pizov G, Neeman ZV, Cohen IR. Binding of anti-DNA antibodies and inhibition of glomerulonephritis in MRL-lpr/lpr mice by heparin. Arthritis Rheum. 1990 Oct; 33(10):1554-9. PMID: 2222535.
      View in: PubMed
    55. Schuger L, O'Shea S, Rheinheimer J, Varani J. Laminin in lung development: effects of anti-laminin antibody in murine lung morphogenesis. Dev Biol. 1990 Jan; 137(1):26-32. PMID: 2403947.
      View in: PubMed
    56. Schuger L, Dixit VM, Carey TE, Varani J. Modulation of squamous carcinoma cell growth, morphology, adhesiveness and extracellular matrix production by interferon-gamma and tumor necrosis factor-alpha. Pathobiology. 1990; 58(5):279-86. PMID: 2127530.
      View in: PubMed
    57. Schuger CD, Steinman RT, Lehmann MH, Schuger L, Boldea D, McMath L, Spears JR. Percutaneous transcatheter laser balloon ablation from the canine coronary sinus: implications for the Wolff-Parkinson-White syndrome. Lasers Surg Med. 1990; 10(2):140-8. PMID: 2332999.
      View in: PubMed
    58. Varani J, Ginsburg I, Schuger L, Gibbs DF, Bromberg J, Johnson KJ, Ryan US, Ward PA. Endothelial cell killing by neutrophils. Synergistic interaction of oxygen products and proteases. Am J Pathol. 1989 Sep; 135(3):435-8. PMID: 2675621.
      View in: PubMed
    59. Schuger L, Varani J, Marks RM, Kunkel SL, Johnson KJ, Ward PA. Cytotoxicity of tumor necrosis factor-alpha for human umbilical vein endothelial cells. Lab Invest. 1989 Jul; 61(1):62-8. PMID: 2747218.
      View in: PubMed
    60. Keren A, Chenzbruna A, Schuger L, Milgarter E, Tzivoni D. The etiology of tumor plop in a patient with huge right atrial myxoma. Chest. 1989 May; 95(5):1147-9. PMID: 2640541.
      View in: PubMed
    61. Ginsburg I, Gibbs DF, Schuger L, Johnson KJ, Ryan US, Ward PA, Varani J. Vascular endothelial cell killing by combinations of membrane-active agents and hydrogen peroxide. Free Radic Biol Med. 1989; 7(4):369-76. PMID: 2558061.
      View in: PubMed
    62. Schuger L, Bonino F, Mushahwar IK, Ron N, Shouval D. Delta virus infection in Jerusalem. Isr J Med Sci. 1988 Mar; 24(3):156-9. PMID: 3286578.
      View in: PubMed
    63. Schuger L, Peretz T, Goldin E, Durst AL, Okon E. Duodenal epithelial atypia. A specific complication of hepatic arterial infusion chemotherapy. Cancer. 1988 Feb 15; 61(4):663-6. PMID: 2962731.
      View in: PubMed
    64. Shouval D, Schuger L, Levij IS, Reid LM, Neeman Z, Shafritz DA. Comparative morphology and tumourigenicity of human hepatocellular carcinoma cell lines in athymic rats and mice. Virchows Arch A Pathol Anat Histopathol. 1988; 412(6):595-606. PMID: 2452511.
      View in: PubMed
    65. Lurie M, Elmalach I, Schuger L, Weintraub Z. Liver findings in infantile cytomegalovirus infection: similarity to extrahepatic biliary obstruction. Histopathology. 1987 Nov; 11(11):1171-80. PMID: 2826325.
      View in: PubMed
    66. Milgalter E, Lotan H, Schuger L, Ben-Horin Y, Uretzky G, Appelbaum A, Borman JB. Cardiac myxomas--surgical experience with a multi-faceted tumor. Thorac Cardiovasc Surg. 1987 Apr; 35(2):115-8. PMID: 2440132.
      View in: PubMed
    67. Schuger L, Ron N, Rosenmann E. Cardiac myxoma. A retrospective immunohistochemical study. Pathol Res Pract. 1987 Feb; 182(1):63-6. PMID: 2438671.
      View in: PubMed
    68. Schuger L, Bonino F, Mushahwar IK, Shouval D. Delta virus infection in Jerusalem. Prog Clin Biol Res. 1987; 234:469. PMID: 3628415.
      View in: PubMed
    69. Lysey J, Eid A, Schuger L. Eosinophilic gastroenteritis with small bowel perforation. J Clin Gastroenterol. 1986 Dec; 8(6):694-5. PMID: 3805670.
      View in: PubMed
    70. Schuger L, Simon A, Okon E. Cytomegaly in benign ovarian cysts. Arch Pathol Lab Med. 1986 Oct; 110(10):928-9. PMID: 3767611.
      View in: PubMed
    71. Wald U, Levy PJ, Rappaport ZH, Michowitz SD, Schuger L, Shalit MN. Conus ganglioglioma in a 2 1/2-year-old boy. Case report. J Neurosurg. 1985 Jan; 62(1):142-4. PMID: 3964847.
      View in: PubMed
    Schuger's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _