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Gregory Roloff

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Hematology and Oncology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Muhsen IN, Roloff GW, Faramand RG, Othman T, Valtis YK, Kopmar NE, Dekker SE, Connor M, Mercadal S, O'Connor TE, Dykes KC, Ahmed M, Jeyakumar N, Zhang A, Miller K, Sutherland KC, Guzowski C, Gupta VK, Majhail NS, Battiwalla M, Solh MM, Malik SA, Mathews J, Oliai C, Shaughnessy PJ, Mountjoy L, Lee CJ, Logan AC, Tsai SB, Leonard JT, Schwartz MS, Sasine JP, Kumaran M, Frey NV, Park JH, Koura D, Cassaday RD, Shah BD, Aldoss I, Muffly LS, Hill LC. Outcomes of Brexucabtagene Autoleucel in Relapsed/Refractory Acute Lymphoblastic Leukemia Patients with CNS Involvement. Blood Adv. 2025 May 07. PMID: 40334068.
      Citations:    Fields:    
    2. Lust H, Schultz LM, Kwon S, Roloff GW, Aldoss I, Baggott C, John S, Rossoff J, McNerney KO, Fabrizio VA, Talano JA, Moskop A, Curran KJ, Phillips CL, Karras NA, Baumeister SHC, Cooper S, Hermiston ML, Satwani P, Qayed M, Raikar SS, MacMillan ML, Hall EM, Nguyen K, Cassaday RD, Kopmar NE, Kota VK, Mathews J, Shaughnessy PJ, Schwartz MS, Ladha A, Yaghmour G, Kumaran M, Bachanova V, Tracy SI, Othman T, Luskin MR, Chen EC, Advani AS, Jeyakumar N, Miller K, Zhang A, Shah BD, Muffly LS, Faramand RG. Real World Outcomes for Young Adult Patients Receiving CD19 CAR T-cell Therapy. Blood Adv. 2025 Mar 24. PMID: 40127395.
      Citations:    Fields:    
    3. Aldoss I, Roloff GW, Faramand RG, Kopmar NE, Lin C, Advani AS, Dekker SE, Gupta VK, O'Connor TE, Jeyakumar N, Muhsen IN, Valtis YK, Zhang A, Miller K, Sutherland KC, Dykes KC, Ahmed M, Chen EC, Zambrano H, Bradshaw D, Mercadal S, Schwartz MS, Tracy SI, Dholaria B, Kubiak MJ, Mukherjee A, Majhail NS, Battiwalla M, Mountjoy L, Malik SA, Mathews J, Shaughnessy PJ, Logan A, Ladha A, Stefan M, Guzowski C, Hoeg RT, Hilal T, Moore J, Connor M, O'Dwyer KM, Hill LC, Tsai SB, Sasine JP, Solh MM, Lee CJ, Kota V, Koura D, Veeraputhiran M, Blunk B, Oliai C, Leonard JT, Frey NV, Park JH, Luskin MR, Bachanova V, Galal A, Bishop MR, Stock W, Cassaday RD, Pullarkat VA, Shah BD, Muffly L, Aldoss I, Roloff GW, Faramand R, Kopmar NE, Lin C, Advani AS, Dekker SE, Gupta VK, O'Connor TE, Jeyakumar N, Muhsen IN, Valtis Y, Zhang A, Miller K, Sutherland K, Dykes KC, Ahmed M, Chen E, Zambrano H, Bradshaw D, Mercadal S, Schwartz M, Tracy S, Dholaria B, Kubiak M, Mukherjee A, Majhail N, Battiwalla M, Mountjoy L, Malik SA, Mathews J, Shaughnessy P, Logan AC, Ladha A, Stefan M, Guzowski C, Hoeg RT, Hilal T, Moore J, Connor M, O'Dwyer KM, Hill LC, Tsai SB, Sasine J, Solh MM, Lee CJ, Kota VK, Koura D, Veeraputhiran M, Blunk B, Oliai C, Leonard JT, Frey NV, Park JH, Luskin MR, Bachanova V, Galal A, Bishop MR, Stock W, Cassaday RD, Pullarkat V, Shah BD, Muffly LS. Impact of prior inotuzumab ozogamicin treatment on brexucabtagene autoleucel outcomes in adults with B-cell ALL. Blood Adv. 2024 Dec 10; 8(23):6139-6147. PMID: 39093952; PMCID: PMC11707416.
      Citations: 2     Fields:    Translation:Humans
    4. Symes EO, Wang P, Sojitra P, Menon MP, Patel AA, Hasan F, Ghosh S, Roloff GW, Zhou Q, Findley A, Badar T, Zhang J, Tariq H, Chang H, Bell RC, Perry AM, Venkataraman G. Somatic co-alteration signatures are prognostic in high-grade TP53-mutated myeloid neoplasms. Br J Haematol. 2025 Apr; 206(4):1103-1108. PMID: 39551719; PMCID: PMC11985366.
      Citations: 1     Fields:    Translation:Humans
    5. Roloff GW, Kosuri S, Nawas MT, DuVall AS, Patel AA, Riedell PA, Odenike O, Stock W, Larson RA, Bishop MR, Nunley E, Godley LA, Hathaway F, Del Gaudio D, Das S, Canham LE, Drazer MW. Expedited evaluation of hereditary hematopoietic malignancies in the setting of stem cell transplantation. Haematologica. 2024 Nov 01; 109(11):3739-3744. PMID: 38618681; PMCID: PMC11532700.
      Citations: 1     Fields:    
    6. Roloff GW, Aldoss I, Kopmar NE, Lin C, Dekker SE, Gupta VK, O'Connor TE, Jeyakumar N, Muhsen IN, Valtis Y, Ahmed N, Zhang A, Miller K, Dykes KC, Ahmed M, Chen EC, Mercadal S, Schwartz M, Tracy SI, Dholaria B, Mukherjee A, Battiwalla M, Logan AC, Ladha A, Guzowski C, Hoeg RT, Hilal T, Moore J, Connor MP, Hill LC, Tsai SB, Sasine JP, Solh MM, Kota VK, Koura D, Veeraputhiran M, Leonard JT, Frey NV, Park JH, Luskin MR, Bachanova V, Galal A, Pullarkat V, Stock W, Cassaday RD, Shah BD, Faramand R, Muffly L, ROCCA Consortium. Outcomes After Brexucabtagene Autoleucel Administered as a Standard Therapy for Adults With Relapsed/Refractory B-Cell ALL. J Clin Oncol. 2025 Feb 10; 43(5):558-566. PMID: 39418622.
      Citations: 3     Fields:    Translation:Humans
    7. Roloff GW, Wen F, Ramsland A, Artz AS, Kosuri S, Stock W, Odenike O, Larson RA, Liu H, Godley LA, Thirman MJ, Patel AA, Daugherty CK, DuVall AS, Nawas MT, Dworkin E, Wool GD, Gurbuxani S, Fitzpatrick C, Segal JP, Wang P, Drazer MW. Clinical and molecular response of acute myeloid leukemia harboring non-canonical FLT3 N676K driver mutations to contemporary FLT3 inhibitors. Haematologica. 2023 08 01; 108(8):2234-2239. PMID: 36655425; PMCID: PMC10388285.
      Citations:    Fields:    Translation:Humans
    8. Shaw R, Haque AR, Luu T, O'Connor TE, Hamidi A, Fitzsimons J, Varda B, Kwon D, Whitcomb C, Gregorowicz A, Roloff GW, Bemiss BC, Kallwitz ER, Hagen PA, Berg S. Multicenter analysis of immunosuppressive medications on the risk of malignancy following adult solid organ transplantation. Front Oncol. 2023; 13:1146002. PMID: 37397376; PMCID: PMC10313202.
      Citations: 1     
    9. Hamidi A, Roloff GW, Shaw R, Acevedo M, Smith S, Drazer MW. Clinical guideline variability in the diagnosis of hereditary hematopoietic malignancy syndromes. Leuk Lymphoma. 2023 09; 64(9):1562-1565. PMID: 37294121.
      Citations: 1     Fields:    Translation:Humans
    10. O'Connor TE, Shaw R, Madero-Marroquin R, Roloff GW. Clinical considerations at the intersection of hematopoietic cell transplantation and hereditary hematopoietic malignancy. Front Oncol. 2023; 13:1180439. PMID: 37251919; PMCID: PMC10213438.
      Citations: 1     
    11. Saygin C, Roloff G, Hahn CN, Chhetri R, Gill S, Elmariah H, Talati C, Nunley E, Gao G, Kim A, Bishop M, Kosuri S, Das S, Singhal D, Venugopal P, Homan CC, Brown A, Scott HS, Hiwase D, Godley LA. Allogeneic hematopoietic stem cell transplant outcomes in adults with inherited myeloid malignancies. Blood Adv. 2023 02 28; 7(4):549-554. PMID: 36001442; PMCID: PMC9979761.
      Citations: 23     Fields:    Translation:Humans
    12. Roloff GW, Shaw R, O'Connor TE, Hathaway F, Drazer MW. Stagnation in quality of next-generation sequencing assays for the diagnosis of hereditary hematopoietic malignancies. J Genet Couns. 2023 06; 32(3):744-749. PMID: 36642751; PMCID: PMC11310923.
      Citations: 3     Fields:    Translation:Humans
    13. Roloff GW, Odenike O, Bajel A, Wei AH, Foley N, Uy GL. Contemporary Approach to Acute Myeloid Leukemia Therapy in 2022. Am Soc Clin Oncol Educ Book. 2022 Apr; 42:1-16. PMID: 35658497.
      Citations: 19     Fields:    Translation:Humans
    14. Roloff GW, Drazer MW, Godley LA. Inherited Susceptibility to Hematopoietic Malignancies in the Era of Precision Oncology. JCO Precis Oncol. 2021 11; 5:107-122. PMID: 34994594.
      Citations: 14     Fields:    Translation:Humans
    15. Aleem A, Haque AR, Roloff GW, Griffiths EA. Application of Next-Generation Sequencing-Based Mutational Profiling in Acute Lymphoblastic Leukemia. Curr Hematol Malig Rep. 2021 10; 16(5):394-404. PMID: 34613552.
      Citations: 3     Fields:    Translation:HumansAnimals
    16. Ahmadmehrabi K, Haque AR, Aleem A, Griffiths EA, Roloff GW. Targeted Therapies for the Evolving Molecular Landscape of Acute Myeloid Leukemia. Cancers (Basel). 2021 Sep 16; 13(18). PMID: 34572873; PMCID: PMC8471378.
      Citations: 6     
    17. Roloff GW, Godley LA, Drazer MW. Assessment of technical heterogeneity among diagnostic tests to detect germline risk variants for hematopoietic malignancies. Genet Med. 2021 01; 23(1):211-214. PMID: 32807974; PMCID: PMC9299956.
      Citations: 6     Fields:    Translation:HumansCells
    18. Roloff GW, Baron JI, Neppalli VT, Sait S, Griffiths EA. Next-Generation Sequencing Delineates Clonal Origins and Informs Therapeutic Strategies in Acute Lymphoblastic Leukemia and Histiocytic Sarcoma. JCO Precis Oncol. 2019 Dec; 3:1-8. PMID: 35100717.
      Citations: 3     Fields:    
    19. Wong HY, Sung AD, Lindblad KE, Sheela S, Roloff GW, Rizzieri D, Goswami M, Mulé MP, Ramos NR, Tang J, Thompson J, DeStefano CB, Romero K, Dillon LW, Kim DY, Lai C, Hourigan CS. Molecular Measurable Residual Disease Testing of Blood During AML Cytotoxic Therapy for Early Prediction of Clinical Response. Front Oncol. 2018; 8:669. PMID: 30697529; PMCID: PMC6341003.
      Citations: 13     
    20. Roloff GW, Griffiths EA. When to obtain genomic data in acute myeloid leukemia (AML) and which mutations matter. Hematology Am Soc Hematol Educ Program. 2018 11 30; 2018(1):35-44. PMID: 30504289; PMCID: PMC6246019.
      Citations: 3     Fields:    Translation:Humans
    21. Roloff GW, Griffiths EA. When to obtain genomic data in acute myeloid leukemia (AML) and which mutations matter. Blood Adv. 2018 11 13; 2(21):3070-3080. PMID: 30425072; PMCID: PMC6234366.
      Citations: 18     Fields:    Translation:Humans
    22. Dillon LW, Hayati S, Roloff GW, Tunc I, Pirooznia M, Mitrofanova A, Hourigan CS. Targeted RNA-sequencing for the quantification of measurable residual disease in acute myeloid leukemia. Haematologica. 2019 02; 104(2):297-304. PMID: 30171026; PMCID: PMC6355494.
      Citations: 23     Fields:    Translation:HumansCells
    23. Griffiths EA, Srivastava P, Matsuzaki J, Brumberger Z, Wang ES, Kocent J, Miller A, Roloff GW, Wong HY, Paluch BE, Lutgen-Dunckley LG, Martens BL, Odunsi K, Karpf AR, Hourigan CS, Nemeth MJ. NY-ESO-1 Vaccination in Combination with Decitabine Induces Antigen-Specific T-lymphocyte Responses in Patients with Myelodysplastic Syndrome. Clin Cancer Res. 2018 03 01; 24(5):1019-1029. PMID: 28947565; PMCID: PMC5844797.
      Citations: 61     Fields:    Translation:HumansCellsCTClinical Trials
    24. Roloff GW, Lai C, Hourigan CS, Dillon LW. Technical Advances in the Measurement of Residual Disease in Acute Myeloid Leukemia. J Clin Med. 2017 Sep 19; 6(9). PMID: 28925935; PMCID: PMC5615280.
      Citations: 15     
    25. Roloff GW, Yang Z, Wood LV, Neychev VK. Colon cancer metastasis to the thyroid gland: report of a case with unique molecular profile. Clin Case Rep. 2016 06; 4(6):549-53. PMID: 27398194; PMCID: PMC4891476.
      Citations: 3     
    26. Meaburn KJ, Agunloye O, Devine M, Leshner M, Roloff GW, True LD, Misteli T. Tissue-of-origin-specific gene repositioning in breast and prostate cancer. Histochem Cell Biol. 2016 Apr; 145(4):433-46. PMID: 26791532; PMCID: PMC4795970.
      Citations: 17     Fields:    Translation:Humans
    27. Leshner M, Devine M, Roloff GW, True LD, Misteli T, Meaburn KJ. Locus-specific gene repositioning in prostate cancer. Mol Biol Cell. 2016 Jan 15; 27(2):236-46. PMID: 26564800; PMCID: PMC4713128.
      Citations: 17     Fields:    Translation:HumansCells
    28. Shabbir A, Zisa D, Lin H, Mastri M, Roloff G, Suzuki G, Lee T. Activation of host tissue trophic factors through JAK-STAT3 signaling: a mechanism of mesenchymal stem cell-mediated cardiac repair. Am J Physiol Heart Circ Physiol. 2010 Nov; 299(5):H1428-38. PMID: 20852053; PMCID: PMC2993206.
      Citations: 47     Fields:    Translation:AnimalsCells
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