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Alexandra Rojek

TitleInstructor
InstitutionUniversity of Chicago
DepartmentMedicine-Hematology and Oncology
AddressChicago IL 60637
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    Alexandra Rojek, MD is a hematologist/oncologist specializing in the care of adults with lymphoma and has a particular interest in the use of chimeric antigen receptor (CAR) T-cell therapy in the treatment of lymphoma patients. She has expertise in the treatment of non-Hodgkin lymphomas, Hodgkin lymphoma, T cell lymphomas, and the role of stem cell transplantation in the treatment of different lymphomas in addition to CAR T cell therapy. Dr. Rojek’s laboratory research focuses on identifying immunology mechanisms underlying the success of cellular therapies and developing strategies to leverage these mechanisms to improve cellular therapy efficacy for patients. Her research aims to then translate these findings into early phase trials utilizing cellular therapies for patients with lymphoma as well as other malignancies.

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rojek AE, McCormick BJ, Cwykiel J, Odetola O, Abaza Y, Nai N, Foucar CE, Achar RK, Shallis RM, Bradshaw D, Standridge M, Kota V, Murthy GSG, Badar T, Patel AA. Real-World Outcomes of Relapsed/Refractory Core-Binding Factor Acute Myeloid Leukemia: A COMMAND Registry Study. Am J Hematol. 2025 Jun; 100(6):1082-1085. PMID: 40062542; PMCID: PMC12068978.
      Citations:    Fields:    
    2. Rojek AE, McCormick BJ, Cwykiel J, Odetola O, Abaza Y, Nai N, Foucar CE, Achar RK, Shallis RM, Bradshaw D, Standridge M, Kota V, Murthy GSG, Badar T, Patel AA. Real-world outcomes of intensive induction approaches in core binding factor acute myeloid leukemia. EJHaem. 2024 Aug; 5(4):728-737. PMID: 39157611; PMCID: PMC11327707.
      Citations: 3     
    3. Ahmed G, Alsouqi A, Szabo A, Samples L, Shadman M, Awan FT, Rojek AE, Riedell PA, Iqbal M, Fenske TS, Kharfan-Dabaja MA, Ito S, Hamadani M. CAR T-cell therapy in mantle cell lymphoma with secondary CNS involvement: a multicenter experience. Blood Adv. 2024 07 09; 8(13):3528-3531. PMID: 38701405; PMCID: PMC11261102.
      Citations: 4     Fields:    Translation:Humans
    4. Kaur A, Rojek AE, Symes E, Nawas MT, Patel AA, Patel JL, Sojitra P, Aqil B, Sukhanova M, McNerney ME, Wu LP, Akmatbekov A, Segal J, Tjota MY, Gurbuxani S, Cheng JX, Yeon SY, Ravisankar HV, Fitzpatrick C, Lager A, Drazer MW, Saygin C, Wanjari P, Katsonis P, Lichtarge O, Churpek JE, Ghosh SB, Patel AB, Menon MP, Arber DA, Wang P, Venkataraman G. Real world predictors of response and 24-month survival in high-grade TP53-mutated myeloid neoplasms. Blood Cancer J. 2024 06 18; 14(1):99. PMID: 38890297; PMCID: PMC11189545.
      Citations: 5     Fields:    Translation:Humans
    5. Alsouqi A, Ahmed G, Wang J, Szabo A, Rojek AE, Riedell PA, Awan F, Samples L, Shadman M, Hu M, Bachanova V, Wesson W, Ahmed N, Iqbal M, Kharfan-Dabaja MA, Scordo M, Johnson PC, Chen YB, Ito S, Hamadani M, Frigault M, Cassanello G. Chimeric antigen receptor T-cell therapy in secondary central nervous system lymphoma: A multicenter analysis. Am J Hematol. 2024 08; 99(8):1624-1627. PMID: 38769663.
      Citations: 6     Fields:    Translation:Humans
    6. Rojek AE, Kline JP, Feinberg N, Appelbaum DE, Pu Y, Derman BA, Jakubowiak A, Kosuri S, Liu H, Nawas MT, Smith SM, Bishop MR, Riedell PA. Optimization of Metabolic Tumor Volume as a Prognostic Marker in CAR T-Cell Therapy for Aggressive Large B-cell NHL. Clin Lymphoma Myeloma Leuk. 2024 02; 24(2):83-93. PMID: 37827881.
      Citations: 6     Fields:    Translation:Humans
    7. Rojek AE, Schiller PT. Residency Training in the COVID-19 Pandemic-Addressing the Need for Systems-Based Education. JAMA Health Forum. 2022 09 02; 3(9):e223023. PMID: 36218931.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    8. Santhosh L, Rojek AE, Yim JWL, Lisker S, Wang K, Dy M, Sarkar U. Analysis of Narrative Text in Evaluations of Continuing Medical Education Faculty by Gender. JAMA Netw Open. 2022 08 01; 5(8):e2227948. PMID: 35994291; PMCID: PMC9396359.
      Citations:    Fields:    Translation:Humans
    9. Rojek AE, Schiller PT. Residents as Innovators on COVID-19 Respiratory Isolation Units. Acad Med. 2022 07 01; 97(7):946-947. PMID: 34554949.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    10. Rojek AE, Smith SM. Evolution of therapy for limited stage diffuse large B-cell lymphoma. Blood Cancer J. 2022 02 24; 12(2):33. PMID: 35210407; PMCID: PMC8867133.
      Citations: 10     Fields:    Translation:Humans
    11. Orellana-Noia VM, Reed DR, McCook AA, Sen JM, Barlow CM, Malecek MK, Watkins M, Kahl BS, Spinner MA, Advani R, Voorhees TJ, Snow A, Grover NS, Ayers A, Romancik J, Liu Y, Huntington SF, Chavez JC, Saeed H, Lazaryan A, Raghunathan V, Spurgeon SE, Ollila TA, Del Prete C, Olszewski A, Ayers EC, Landsburg DJ, Echalier B, Lee J, Kamdar M, Caimi PF, Fu T, Liu J, David KA, Alharthy H, Law J, Karmali R, Shah H, Stephens DM, Major A, Rojek AE, Smith SM, Yellala A, Kallam A, Nakhoda S, Khan N, Sohail MA, Hill BT, Barrett-Campbell O, Lansigan F, Switchenko J, Cohen J, Portell CA. Single-route CNS prophylaxis for aggressive non-Hodgkin lymphomas: real-world outcomes from 21 US academic institutions. Blood. 2022 01 20; 139(3):413-423. PMID: 34570876; PMCID: PMC8777199.
      Citations: 37     Fields:    Translation:Humans
    12. Patel AA, Rojek AE, Drazer MW, Weiner H, Godley LA, Le Beau MM, Larson RA. Therapy-related myeloid neoplasms in 109 patients after radiation monotherapy. Blood Adv. 2021 10 26; 5(20):4140-4148. PMID: 34492705; PMCID: PMC8945635.
      Citations: 13     Fields:    Translation:HumansCells
    13. Jasielec JK, Kubicki T, Raje N, Vij R, Reece D, Berdeja J, Derman BA, Rosenbaum CA, Richardson P, Gurbuxani S, Major S, Wolfe B, Stefka AT, Stephens L, Tinari KM, Hycner T, Rojek AE, Dytfeld D, Griffith KA, Zimmerman TM, Jakubowiak AJ. Carfilzomib, lenalidomide, and dexamethasone plus transplant in newly diagnosed multiple myeloma. Blood. 2020 11 26; 136(22):2513-2523. PMID: 32735641; PMCID: PMC7714092.
      Citations: 35     Fields:    Translation:HumansCTClinical Trials
    14. Patel AA, Thomas J, Rojek AE, Stock W. Biology and Treatment Paradigms in T Cell Acute Lymphoblastic Leukemia in Older Adolescents and Adults. Curr Treat Options Oncol. 2020 05 28; 21(7):57. PMID: 32468488.
      Citations: 22     Fields:    Translation:Humans
    15. Rojek AE, Khanna R, Yim JWL, Gardner R, Lisker S, Hauer KE, Lucey C, Sarkar U. Differences in Narrative Language in Evaluations of Medical Students by Gender and Under-represented Minority Status. J Gen Intern Med. 2019 05; 34(5):684-691. PMID: 30993609; PMCID: PMC6502922.
      Citations: 71     Fields:    Translation:Humans
    16. Riback JA, Katanski CD, Kear-Scott JL, Pilipenko EV, Rojek AE, Sosnick TR, Drummond DA. Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response. Cell. 2017 03 09; 168(6):1028-1040.e19. PMID: 28283059; PMCID: PMC5401687.
      Citations: 431     Fields:    Translation:AnimalsCells
    17. Wallace EW, Kear-Scott JL, Pilipenko EV, Schwartz MH, Laskowski PR, Rojek AE, Katanski CD, Riback JA, Dion MF, Franks AM, Airoldi EM, Pan T, Budnik BA, Drummond DA. Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress. Cell. 2015 Sep 10; 162(6):1286-98. PMID: 26359986; PMCID: PMC4567705.
      Citations: 251     Fields:    Translation:AnimalsCells
    18. Ko SB, Luo X, Hager H, Rojek A, Choi JY, Licht C, Suzuki M, Muallem S, Nielsen S, Ishibashi K. AE4 is a DIDS-sensitive Cl(-)/HCO(-)(3) exchanger in the basolateral membrane of the renal CCD and the SMG duct. Am J Physiol Cell Physiol. 2002 Oct; 283(4):C1206-18. PMID: 12225984.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
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