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Asish Ghosh

TitleResearch Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Cardiology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mamidi MK, Sinha S, Mendez MT, Sanyal T, Mahmud H, Kay NE, Gupta M, Xu C, Vesely SK, Mukherjee P, Holter Chakrabarty J, Ghosh AK. Aberrantly Expressed Mitochondrial Lipid Kinase, AGK Activates JAK2-Histone H3 Axis and BCR Signal: A Mechanistic Study with Implication in CLL Therapy. Clin Cancer Res. 2024 Dec 05. PMID: 39636206.
      Citations:    Fields:    
    2. Islam SRU, Ghosh AK, Begum MN, Siddike Shakil MS, Jahan M, Huda AQ. The Distribution of Respiratory Viral Pathogens Among the Symptomatic Respiratory Tract Infection Patients From Dhaka City in the Pre-COVID-19 Pandemic Era. Cureus. 2024 Oct; 16(10):e70781. PMID: 39493125; PMCID: PMC11531312.
      Citations:    
    3. Lytton SD, Ghosh AK. SARS-CoV-2 Variants and COVID-19 in Bangladesh-Lessons Learned. Viruses. 2024 Jul 04; 16(7). PMID: 39066238; PMCID: PMC11281597.
      Citations:    Fields:    Translation:HumansCells
    4. Sinha S, Guo R, Del Busso MD, Han W, Boysen J, Wellik LE, Ghosh AK, Kay NE. Aberrant activation of AXL may drive progression of squamous cell carcinoma in CLL patients: a mechanistic study with clinical implications. Br J Cancer. 2024 Aug; 131(3):589-600. PMID: 38886556; PMCID: PMC11300914.
      Citations:    Fields:    Translation:HumansCells
    5. Lytton SD, Ghosh AK, Bulbul RH, Nasifa T, Mamunur R, Meier C, Landt O, Kaiser M. The severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) omicron sub-variants in Bangladesh cause mild COVID-19 and associate with similar antibody responses irrespective of natural infection or vaccination history. Heliyon. 2024 May 30; 10(10):e31011. PMID: 38770337; PMCID: PMC11103536.
      Citations: 1     
    6. Benfer KA, Whittingham K, Ware RS, Ghosh AK, Chowdhury S, Moula G, Samanta S, Khan NZ, Bell KL, Oftedal S, Bandaranayake S, Salt AT, Bhattacharya A, Maiti P, Tripathi SK, Morgan C, Novak I, Boyd RN. Efficacy of Early Intervention for Infants With Cerebral Palsy in an LMIC: An RCT. Pediatrics. 2024 Apr 01; 153(4). PMID: 38516717.
      Citations: 1     Fields:    Translation:Humans
    7. Rottmann M, Yoo S, Pfenniger A, Mikhailov A, Benefield B, Johnson DA, Zhang W, Ghosh AK, Kim D, Passman R, Knight BP, Lee DC, Arora R. Use of Atrial Fibrillation Electrograms and T1/T2 Magnetic Resonance Imaging to Define the Progressive Nature of Molecular and Structural Remodeling: A New Paradigm Underlying the Emergence of Persistent Atrial Fibrillation. J Am Heart Assoc. 2024 Mar 05; 13(5):e032514. PMID: 37930082; PMCID: PMC10944076.
      Citations:    Fields:    Translation:Animals
    8. Ghosh AK, Kalousdian AA, Shang M, Lux E, Eren M, Keating A, Wilsbacher LD, Vaughan DE. Cardiomyocyte PAI-1 influences the cardiac transcriptome and limits the extent of cardiac fibrosis in response to left ventricular pressure overload. Cell Signal. 2023 04; 104:110555. PMID: 36584735.
      Citations: 2     Fields:    Translation:AnimalsCells
    9. Ghosh AK, Landt O, Yeasmin M, Sharif M, Ratul RH, Molla MA, Nafisa T, Mosaddeque MB, Hosen N, Bulbul MRH, Mamunur R, Islam A, Shakil SS, Kaiser M, Amin MR, Lytton SD. Clinical Presentation of COVID-19 and Antibody Responses in Bangladeshi Patients Infected with the Delta or Omicron Variants of SARS-CoV-2. Vaccines (Basel). 2022 Nov 18; 10(11). PMID: 36423054; PMCID: PMC9694163.
      Citations: 6     
    10. Mamidi MK, Mahmud H, Maiti GP, Mendez MT, Fernandes SM, Vesely SK, Holter-Chakrabarty J, Brown JR, Ghosh AK. Idelalisib activates AKT via increased recruitment of PI3Kd/PI3Kß to BCR signalosome while reducing PDK1 in post-therapy CLL cells. Leukemia. 2022 07; 36(7):1806-1817. PMID: 35568768; PMCID: PMC10874218.
      Citations: 2     Fields:    Translation:Humans
    11. Islam SRU, Akther T, Sultana S, Deb P, Ghosh AK, Nasif MAO, Bhuiyan AH, Jahan M, Nessa A, Munshi SU, Tabassum S. Challenges in the establishment of a biosafety testing laboratory for COVID-19 in Bangladesh. J Infect Dev Ctries. 2021 12 31; 15(12):1833-1837. PMID: 35044940.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    12. Hoque MN, Sarkar MMH, Rahman MS, Akter S, Banu TA, Goswami B, Jahan I, Hossain MS, Shamsuzzaman AKM, Nafisa T, Molla MMA, Yeasmin M, Ghosh AK, Osman E, Alam SKS, Uzzaman MS, Habib MA, Mahmud ASM, Crandall KA, Islam T, Khan MS. SARS-CoV-2 infection reduces human nasopharyngeal commensal microbiome with inclusion of pathobionts. Sci Rep. 2021 12 15; 11(1):24042. PMID: 34911967; PMCID: PMC8674272.
      Citations: 20     Fields:    Translation:HumansCells
    13. Ghosh AK, Kaiser M, Molla MMA, Nafisa T, Yeasmin M, Ratul RH, Sharif MM, Akram A, Hosen N, Mamunur R, Amin MR, Islam A, Hoque ME, Landt O, Lytton SD. Molecular and Serological Characterization of the SARS-CoV-2 Delta Variant in Bangladesh in 2021. Viruses. 2021 11 19; 13(11). PMID: 34835116; PMCID: PMC8623815.
      Citations: 8     Fields:    Translation:HumansCells
    14. Ghosh AK. Acetyltransferase p300 Is a Putative Epidrug Target for Amelioration of Cellular Aging-Related Cardiovascular Disease. Cells. 2021 10 22; 10(11). PMID: 34831061; PMCID: PMC8616404.
      Citations: 10     Fields:    Translation:HumansAnimals
    15. Molla MMA, Yeasmin M, Ghosh AK, Nafisa T, Islam MK, Saif-Ur-Rahman KM. HIV-1 molecular epidemiology in Bangladesh: A systematic review. Health Sci Rep. 2021 Sep; 4(3):e344. PMID: 34355065; PMCID: PMC8323838.
      Citations: 1     
    16. Lytton SD, Yeasmin M, Ghosh AK, Bulbul MRH, Molla MMA, Herr M, Duchmann H, Sharif MM, Nafisa T, Amin MR, Hosen N, Rahman MT, Islam S, Islam A, Shamsuzzaman AKM. Detection of Anti-Nucleocapsid Antibody in COVID-19 Patients in Bangladesh Is not Correlated with Previous Dengue Infection. Pathogens. 2021 May 22; 10(6). PMID: 34067281; PMCID: PMC8224749.
      Citations: 5     
    17. Maiti GP, Sinha S, Mahmud H, Boysen J, Mendez MT, Vesely SK, Holter-Chakrabarty J, Kay NE, Ghosh AK. SIRT3 overexpression and epigenetic silencing of catalase regulate ROS accumulation in CLL cells activating AXL signaling axis. Blood Cancer J. 2021 05 17; 11(5):93. PMID: 34001853; PMCID: PMC8129117.
      Citations: 9     Fields:    Translation:HumansCells
    18. Ghosh AK, Soberanes S, Lux E, Shang M, Aillon RP, Eren M, Budinger GRS, Miyata T, Vaughan DE. Pharmacological inhibition of PAI-1 alleviates cardiopulmonary pathologies induced by exposure to air pollutants PM2.5. Environ Pollut. 2021 Oct 15; 287:117283. PMID: 34426376; PMCID: PMC8434953.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    19. Molla MMA, Disha JA, Yeasmin M, Ghosh AK, Nafisa T. Decreasing transmission and initiation of countrywide vaccination: Key challenges for future management of COVID-19 pandemic in Bangladesh. Int J Health Plann Manage. 2021 Jul; 36(4):1014-1029. PMID: 33764580; PMCID: PMC8251276.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    20. Molla MMA, Yeasmin M, Islam MK, Sharif MM, Amin MR, Nafisa T, Ghosh AK, Parveen M, Arif MMH, Alam JAJ, Rizvi SJR, Saif-Ur-Rahman KM, Akram A, Shamsuzzaman AKM. Antibiotic Prescribing Patterns at COVID-19 Dedicated Wards in Bangladesh: Findings from a Single Center Study. Infect Prev Pract. 2021 Jun; 3(2):100134. PMID: 34316576; PMCID: PMC7910658.
      Citations: 23     
    21. Sinha S, Secreto CR, Boysen JC, Lesnick C, Wang Z, Ding W, Call TG, Kenderian SJ, Parikh SA, Warner SL, Bearss DJ, Ghosh AK, Kay NE. Upregulation of AXL and ß-catenin in chronic lymphocytic leukemia cells cultured with bone marrow stroma cells is associated with enhanced drug resistance. Blood Cancer J. 2021 02 18; 11(2):37. PMID: 33602892; PMCID: PMC7893033.
      Citations: 2     Fields:    Translation:HumansCells
    22. Ghosh AK. Pharmacological activation of PPAR-?: a potential therapy for skin fibrosis. Int J Dermatol. 2021 Mar; 60(3):376-383. PMID: 33377189.
      Citations: 7     Fields:    Translation:HumansCells
    23. Akter S, Banu TA, Goswami B, Osman E, Uzzaman MS, Habib MA, Jahan I, Mahmud ASM, Sarker MMH, Hossain MS, Shamsuzzaman AKM, Nafisa T, Molla MMA, Yeasmin M, Ghosh AK, Al Din SMS, Ray UC, Sajib SA, Hossain M, Khan MS. Coding-Complete Genome Sequences of Three SARS-CoV-2 Strains from Bangladesh. Microbiol Resour Announc. 2020 Sep 24; 9(39). PMID: 32972934; PMCID: PMC7516145.
      Citations: 6     
    24. Ghosh AK. p300 in Cardiac Development and Accelerated Cardiac Aging. Aging Dis. 2020 Jul; 11(4):916-926. PMID: 32765954; PMCID: PMC7390535.
      Citations: 23     Fields:    
    25. Mahmud H, Mendez M, Mukhopadhyay B, Holter-Chakrabarty J, Ghosh AK. HSP90 overexpression potentiates the B-cell receptor and fibroblast growth factor receptor survival signals in chronic lymphocytic leukemia cells. Oncotarget. 2020 Jun 02; 11(22):2037-2046. PMID: 32547702; PMCID: PMC7275782.
      Citations: 2     Fields:    
    26. Sun T, Ghosh AK, Eren M, Miyata T, Vaughan DE. PAI-1 contributes to homocysteine-induced cellular senescence. Cell Signal. 2019 12; 64:109394. PMID: 31472244; PMCID: PMC6936332.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    27. Rai R, Sun T, Ramirez V, Lux E, Eren M, Vaughan DE, Ghosh AK. Acetyltransferase p300 inhibitor reverses hypertension-induced cardiac fibrosis. J Cell Mol Med. 2019 04; 23(4):3026-3031. PMID: 30710427; PMCID: PMC6433695.
      Citations: 38     Fields:    Translation:AnimalsCells
    28. Sinha S, Boysen JC, Chaffee KG, Kabat BF, Slager SL, Parikh SA, Secreto CR, Call T, Shanafelt TD, Leis JF, Warner SL, Bearss DJ, Ghosh AK, Kay NE. Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy. Oncotarget. 2018 Dec 14; 9(98):37173-37184. PMID: 30647852; PMCID: PMC6324680.
      Citations: 9     Fields:    
    29. Benfer KA, Novak I, Morgan C, Whittingham K, Khan NZ, Ware RS, Bell KL, Bandaranayake S, Salt A, Ghosh AK, Bhattacharya A, Samanta S, Moula G, Bose D, Tripathi S, Boyd RN. Community-based parent-delivered early detection and intervention programme for infants at high risk of cerebral palsy in a low-resource country (Learning through Everyday Activities with Parents (LEAP-CP): protocol for a randomised controlled trial. BMJ Open. 2018 06 22; 8(6):e021186. PMID: 29934387; PMCID: PMC6020941.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    30. Souma T, Thomson BR, Heinen S, Carota IA, Yamaguchi S, Onay T, Liu P, Ghosh AK, Li C, Eremina V, Hong YK, Economides AN, Vestweber D, Peters KG, Jin J, Quaggin SE. Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP. Proc Natl Acad Sci U S A. 2018 02 06; 115(6):1298-1303. PMID: 29358379; PMCID: PMC5819405.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    31. Rai R, Verma SK, Kim D, Ramirez V, Lux E, Li C, Sahoo S, Wilsbacher LD, Vaughan DE, Quaggin SE, Ghosh AK. A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis. Epigenetics. 2017; 12(11):1004-1013. PMID: 28933600; PMCID: PMC5788418.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    32. Rai R, Ghosh AK, Eren M, Mackie AR, Levine DC, Kim SY, Cedernaes J, Ramirez V, Procissi D, Smith LH, Woodruff TK, Bass J, Vaughan DE. Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan. Cell Rep. 2017 Nov 07; 21(6):1471-1480. PMID: 29117554; PMCID: PMC5892413.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    33. Maiti GP, Kay NE, Ghosh AK. Microvesicles in CLL: predictor of disease progression/relapse. Oncotarget. 2017 Oct 31; 8(53):90632-90633. PMID: 29207590; PMCID: PMC5710871.
      Citations: 1     Fields:    
    34. Flevaris P, Khan SS, Eren M, Schuldt AJT, Shah SJ, Lee DC, Gupta S, Shapiro AD, Burridge PW, Ghosh AK, Vaughan DE. Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-ß and Cardiac Fibrosis. Circulation. 2017 Aug 15; 136(7):664-679. PMID: 28588076; PMCID: PMC5784400.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    35. Vaughan DE, Rai R, Khan SS, Eren M, Ghosh AK. Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence. Arterioscler Thromb Vasc Biol. 2017 08; 37(8):1446-1452. PMID: 28572158; PMCID: PMC5846199.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    36. Ghosh AK, Rai R, Flevaris P, Vaughan DE. Epigenetics in Reactive and Reparative Cardiac Fibrogenesis: The Promise of Epigenetic Therapy. J Cell Physiol. 2017 Aug; 232(8):1941-1956. PMID: 27883184.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    37. Ghosh AK, Rai R, Park KE, Eren M, Miyata T, Wilsbacher LD, Vaughan DE. A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence. Oncotarget. 2016 Nov 08; 7(45):72443-72457. PMID: 27736799; PMCID: PMC5341920.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    38. Nagpal V, Rai R, Place AT, Murphy SB, Verma SK, Ghosh AK, Vaughan DE. Response to Letter Regarding Article, "MiR-125b Is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis". Circulation. 2016 Jun 14; 133(24):e714. PMID: 27297354.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    39. Kay NE, Sassoon T, Secreto C, Sinha S, Shanafelt TD, Ghosh AK, Arbiser JL. Tris (dibenzylideneacetone) dipalladium: a small-molecule palladium complex is effective in inducing apoptosis in chronic lymphocytic leukemia B-cells. Leuk Lymphoma. 2016 10; 57(10):2409-16. PMID: 27189785; PMCID: PMC5142299.
      Citations: 8     Fields:    Translation:HumansCells
    40. Nagpal V, Rai R, Place AT, Murphy SB, Verma SK, Ghosh AK, Vaughan DE. MiR-125b Is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis. Circulation. 2016 Jan 19; 133(3):291-301. PMID: 26585673; PMCID: PMC5446084.
      Citations: 124     Fields:    Translation:HumansAnimalsCells
    41. Sinha S, Boysen J, Nelson M, Secreto C, Warner SL, Bearss DJ, Lesnick C, Shanafelt TD, Kay NE, Ghosh AK. Targeted Axl Inhibition Primes Chronic Lymphocytic Leukemia B Cells to Apoptosis and Shows Synergistic/Additive Effects in Combination with BTK Inhibitors. Clin Cancer Res. 2015 May 01; 21(9):2115-26. PMID: 25673699; PMCID: PMC4479154.
      Citations: 45     Fields:    Translation:HumansCells
    42. Thomson BR, Heinen S, Jeansson M, Ghosh AK, Fatima A, Sung HK, Onay T, Chen H, Yamaguchi S, Economides AN, Flenniken A, Gale NW, Hong YK, Fawzi A, Liu X, Kume T, Quaggin SE. A lymphatic defect causes ocular hypertension and glaucoma in mice. J Clin Invest. 2014 Oct; 124(10):4320-4. PMID: 25202984; PMCID: PMC4191022.
      Citations: 95     Fields:    Translation:AnimalsCells
    43. Ghosh AK. FAT-free p300 is good for scar-free tissue repair. J Cell Biochem. 2014 Sep; 115(9):1486-9. PMID: 24733520.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    44. Maezawa Y, Onay T, Scott RP, Keir LS, Dimke H, Li C, Eremina V, Maezawa Y, Jeansson M, Shan J, Binnie M, Lewin M, Ghosh A, Miner JH, Vainio SJ, Quaggin SE. Loss of the podocyte-expressed transcription factor Tcf21/Pod1 results in podocyte differentiation defects and FSGS. J Am Soc Nephrol. 2014 Nov; 25(11):2459-70. PMID: 24904088; PMCID: PMC4214535.
      Citations: 31     Fields:    Translation:AnimalsCells
    45. Ferrajoli A, Shanafelt TD, Ivan C, Shimizu M, Rabe KG, Nouraee N, Ikuo M, Ghosh AK, Lerner S, Rassenti LZ, Xiao L, Hu J, Reuben JM, Calin S, You MJ, Manning JT, Wierda WG, Estrov Z, O'Brien S, Kipps TJ, Keating MJ, Kay NE, Calin GA. Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia. Blood. 2013 Sep 12; 122(11):1891-9. PMID: 23821659; PMCID: PMC3779381.
      Citations: 102     Fields:    Translation:HumansCells
    46. Ghosh AK, Murphy SB, Kishore R, Vaughan DE. Global gene expression profiling in PAI-1 knockout murine heart and kidney: molecular basis of cardiac-selective fibrosis. PLoS One. 2013; 8(5):e63825. PMID: 23724005; PMCID: PMC3665822.
      Citations: 23     Fields:    Translation:AnimalsCells
    47. Ghosh AK, Quaggin SE, Vaughan DE. Molecular basis of organ fibrosis: potential therapeutic approaches. Exp Biol Med (Maywood). 2013 May; 238(5):461-81. PMID: 23856899.
      Citations: 74     Fields:    Translation:HumansAnimals
    48. Yin H, Lo JH, Kim JY, Marsh EE, Kim JJ, Ghosh AK, Bulun S, Chakravarti D. Expression profiling of nuclear receptors identifies key roles of NR4A subfamily in uterine fibroids. Mol Endocrinol. 2013 May; 27(5):726-40. PMID: 23550059; PMCID: PMC3634117.
      Citations: 11     Fields:    Translation:HumansCells
    49. Ghosh AK, Bhattacharyya S, Lafyatis R, Farina G, Yu J, Thimmapaya B, Wei J, Varga J. p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-ß: epigenetic feed-forward amplification of fibrosis. J Invest Dermatol. 2013 May; 133(5):1302-10. PMID: 23303459; PMCID: PMC3626729.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    50. Ghosh AK, Kay NE. Critical signal transduction pathways in CLL. Adv Exp Med Biol. 2013; 792:215-39. PMID: 24014299; PMCID: PMC3918736.
      Citations: 7     Fields:    Translation:HumansCells
    51. Shanafelt TD, Call TG, Zent CS, Leis JF, LaPlant B, Bowen DA, Roos M, Laumann K, Ghosh AK, Lesnick C, Lee MJ, Yang CS, Jelinek DF, Erlichman C, Kay NE. Phase 2 trial of daily, oral Polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia. Cancer. 2013 Jan 15; 119(2):363-70. PMID: 22760587; PMCID: PMC3902473.
      Citations: 76     Fields:    Translation:HumansCTClinical Trials
    52. Verma SK, Krishnamurthy P, Barefield D, Singh N, Gupta R, Lambers E, Thal M, Mackie A, Hoxha E, Ramirez V, Qin G, Sadayappan S, Ghosh AK, Kishore R. Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-?B. Circulation. 2012 Jul 24; 126(4):418-29. PMID: 22705886; PMCID: PMC3422741.
      Citations: 85     Fields:    Translation:AnimalsCells
    53. Ghosh AK, Vaughan DE. PAI-1 in tissue fibrosis. J Cell Physiol. 2012 Feb; 227(2):493-507. PMID: 21465481; PMCID: PMC3204398.
      Citations: 314     Fields:    Translation:Humans
    54. Ghosh AK, Nagpal V, Covington JW, Michaels MA, Vaughan DE. Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): differential expression of microRNAs during EndMT. Cell Signal. 2012 May; 24(5):1031-6. PMID: 22245495; PMCID: PMC3298765.
      Citations: 83     Fields:    Translation:AnimalsCells
    55. Ghosh AK, Vaughan DE. Fibrosis: is it a coactivator disease? Front Biosci (Elite Ed). 2012 01 01; 4(4):1556-70. PMID: 22201975.
      Citations: 10     Fields:    Translation:Humans
    56. Budinger GR, Wu M, Lam AP, Zirk A, Rivera S, Urich D, Chiarella SE, Go LH, Ghosh AK, Selman M, Pardo A, Varga J, Kamp DW, Chandel NS, Sznajder JI, Jain M, Mutlu GM. Proteasomal inhibition after injury prevents fibrosis by modulating TGF-ß(1) signalling. Thorax. 2012 Feb; 67(2):139-46. PMID: 21921091; PMCID: PMC3595535.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    57. Jain M, Budinger GR, Lo A, Urich D, Rivera SE, Ghosh AK, Gonzalez A, Chiarella SE, Marks K, Donnelly HK, Soberanes S, Varga J, Radigan KA, Chandel NS, Mutlu GM. Leptin promotes fibroproliferative acute respiratory distress syndrome by inhibiting peroxisome proliferator-activated receptor-?. Am J Respir Crit Care Med. 2011 Jun 01; 183(11):1490-8. PMID: 21317313; PMCID: PMC3266063.
      Citations: 62     Fields:    Translation:HumansAnimals
    58. Ghosh AK, Secreto C, Boysen J, Sassoon T, Shanafelt TD, Mukhopadhyay D, Kay NE. The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases: implications for therapy. Blood. 2011 Feb 10; 117(6):1928-37. PMID: 21135257; PMCID: PMC3056640.
      Citations: 65     Fields:    Translation:HumansCells
    59. Shanafelt T, Zent C, Byrd J, Erlichman C, Laplant B, Ghosh A, Call T, Villalona-Calero M, Jelinek D, Bowen D, Laumann K, Wu W, Hanson C, Kay N. Phase II trials of single-agent anti-VEGF therapy for patients with chronic lymphocytic leukemia. Leuk Lymphoma. 2010 Dec; 51(12):2222-9. PMID: 21054149; PMCID: PMC3928074.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    60. Wei J, Ghosh AK, Sargent JL, Komura K, Wu M, Huang QQ, Jain M, Whitfield ML, Feghali-Bostwick C, Varga J. PPAR? downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis. PLoS One. 2010 Nov 02; 5(11):e13778. PMID: 21072170; PMCID: PMC2970611.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    61. Ghosh AK, Bradham WS, Gleaves LA, De Taeye B, Murphy SB, Covington JW, Vaughan DE. Genetic deficiency of plasminogen activator inhibitor-1 promotes cardiac fibrosis in aged mice: involvement of constitutive transforming growth factor-beta signaling and endothelial-to-mesenchymal transition. Circulation. 2010 Sep 21; 122(12):1200-9. PMID: 20823384.
      Citations: 62     Fields:    Translation:AnimalsCells
    62. Ghosh AK, Secreto CR, Knox TR, Ding W, Mukhopadhyay D, Kay NE. Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression. Blood. 2010 Mar 04; 115(9):1755-64. PMID: 20018914; PMCID: PMC2832808.
      Citations: 114     Fields:    Translation:HumansCells
    63. Sinha S, Dutta S, Datta K, Ghosh AK, Mukhopadhyay D. Von Hippel-Lindau gene product modulates TIS11B expression in renal cell carcinoma: impact on vascular endothelial growth factor expression in hypoxia. J Biol Chem. 2009 Nov 20; 284(47):32610-8. PMID: 19801654; PMCID: PMC2781675.
      Citations: 16     Fields:    Translation:HumansCells
    64. Ding W, Nowakowski GS, Knox TR, Boysen JC, Maas ML, Schwager SM, Wu W, Wellik LE, Dietz AB, Ghosh AK, Secreto CR, Medina KL, Shanafelt TD, Zent CS, Call TG, Kay NE. Bi-directional activation between mesenchymal stem cells and CLL B-cells: implication for CLL disease progression. Br J Haematol. 2009 Nov; 147(4):471-83. PMID: 19751240; PMCID: PMC2783570.
      Citations: 40     Fields:    Translation:HumansCells
    65. Shanafelt TD, Call TG, Zent CS, LaPlant B, Bowen DA, Roos M, Secreto CR, Ghosh AK, Kabat BF, Lee MJ, Yang CS, Jelinek DF, Erlichman C, Kay NE. Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia. J Clin Oncol. 2009 Aug 10; 27(23):3808-14. PMID: 19470922; PMCID: PMC2727287.
      Citations: 73     Fields:    Translation:HumansCTClinical Trials
    66. Ghosh AK, Bhattacharyya S, Wei J, Kim S, Barak Y, Mori Y, Varga J. Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator. FASEB J. 2009 Sep; 23(9):2968-77. PMID: 19395477; PMCID: PMC2735362.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    67. Ghosh AK, Shanafelt TD, Cimmino A, Taccioli C, Volinia S, Liu CG, Calin GA, Croce CM, Chan DA, Giaccia AJ, Secreto C, Wellik LE, Lee YK, Mukhopadhyay D, Kay NE. Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells. Blood. 2009 May 28; 113(22):5568-74. PMID: 19336759; PMCID: PMC2689054.
      Citations: 59     Fields:    Translation:HumansCells
    68. Ghosh AK, Kay NE, Secreto CR, Shanafelt TD. Curcumin inhibits prosurvival pathways in chronic lymphocytic leukemia B cells and may overcome their stromal protection in combination with EGCG. Clin Cancer Res. 2009 Feb 15; 15(4):1250-8. PMID: 19228728; PMCID: PMC3893060.
      Citations: 48     Fields:    Translation:HumansCells
    69. Cai J, Yi FF, Yang L, Shen DF, Yang Q, Li A, Ghosh AK, Bian ZY, Yan L, Tang QZ, Li H, Yang XC. Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling. Hypertension. 2009 Mar; 53(3):539-48. PMID: 19204184; PMCID: PMC2845399.
      Citations: 14     Fields:    Translation:AnimalsCells
    70. Wu M, Melichian DS, Chang E, Warner-Blankenship M, Ghosh AK, Varga J. Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma. Am J Pathol. 2009 Feb; 174(2):519-33. PMID: 19147827; PMCID: PMC2630560.
      Citations: 116     Fields:    Translation:AnimalsCells
    71. Ghosh AK, Kanda T, Steele R, Ray RB. Knockdown of MBP-1 in human foreskin fibroblasts induces p53-p21 dependent senescence. PLoS One. 2008; 3(10):e3384. PMID: 18852884; PMCID: PMC2557062.
      Citations: 6     Fields:    Translation:HumansCells
    72. Ghosh AK, Wei J, Wu M, Varga J. Constitutive Smad signaling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferator-activated receptor-gamma. Biochem Biophys Res Commun. 2008 Sep 19; 374(2):231-6. PMID: 18627765; PMCID: PMC3157939.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    73. Li HL, Liu C, de Couto G, Ouzounian M, Sun M, Wang AB, Huang Y, He CW, Shi Y, Chen X, Nghiem MP, Liu Y, Chen M, Dawood F, Fukuoka M, Maekawa Y, Zhang L, Leask A, Ghosh AK, Kirshenbaum LA, Liu PP. Curcumin prevents and reverses murine cardiac hypertrophy. J Clin Invest. 2008 Mar; 118(3):879-93. PMID: 18292803; PMCID: PMC2248327.
      Citations: 41     Fields:    Translation:AnimalsCells
    74. Ghosh AK, Varga J. The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis. J Cell Physiol. 2007 Dec; 213(3):663-71. PMID: 17559085.
      Citations: 94     Fields:    Translation:HumansAnimalsCells
    75. Ghosh AK, Mori Y, Dowling E, Varga J. Trichostatin A blocks TGF-beta-induced collagen gene expression in skin fibroblasts: involvement of Sp1. Biochem Biophys Res Commun. 2007 Mar 09; 354(2):420-6. PMID: 17234156.
      Citations: 32     Fields:    Translation:HumansCells
    76. Ghosh AK, Steele R, Ryerse J, Ray RB. Tumor-suppressive effects of MBP-1 in non-small cell lung cancer cells. Cancer Res. 2006 Dec 15; 66(24):11907-12. PMID: 17178888.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    77. Ghosh AK, Steele R, Ray RB. Knockdown of MBP-1 in human prostate cancer cells delays cell cycle progression. J Biol Chem. 2006 Aug 18; 281(33):23652-7. PMID: 16762917.
      Citations: 8     Fields:    Translation:HumansCells
    78. Ghosh AK, Bhattacharyya S, Mori Y, Varga J. Inhibition of collagen gene expression by interferon-gamma: novel role of the CCAAT/enhancer binding protein beta (C/EBPbeta). J Cell Physiol. 2006 Apr; 207(1):251-60. PMID: 16331681.
      Citations: 15     Fields:    Translation:HumansCells
    79. Ray D, Terao Y, Nimbalkar D, Chu LH, Donzelli M, Tsutsui T, Zou X, Ghosh AK, Varga J, Draetta GF, Kiyokawa H. Transforming growth factor beta facilitates beta-TrCP-mediated degradation of Cdc25A in a Smad3-dependent manner. Mol Cell Biol. 2005 Apr; 25(8):3338-47. PMID: 15798217; PMCID: PMC1069597.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    80. Bhattacharyya S, Ghosh AK, Pannu J, Mori Y, Takagawa S, Chen G, Trojanowska M, Gilliam AC, Varga J. Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta. Arthritis Rheum. 2005 Apr; 52(4):1248-58. PMID: 15818659.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    81. Ghosh AK, Steele R, Ray RB. c-myc Promoter-binding protein 1 (MBP-1) regulates prostate cancer cell growth by inhibiting MAPK pathway. J Biol Chem. 2005 Apr 08; 280(14):14325-30. PMID: 15805119.
      Citations: 23     Fields:    Translation:HumansCells
    82. Ghosh AK, Steele R, Ray RB. Carboxyl-terminal repressor domain of MBP-1 is sufficient for regression of prostate tumor growth in nude mice. Cancer Res. 2005 Feb 01; 65(3):718-21. PMID: 15705866.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    83. Halder A, Raychowdhury R, Ghosh A, De M. Black tea (Camellia sinensis) as a chemopreventive agent in oral precancerous lesions. J Environ Pathol Toxicol Oncol. 2005; 24(2):141-4. PMID: 15831086.
      Citations: 5     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    84. Ghosh AK, Bhattacharyya S, Varga J. The tumor suppressor p53 abrogates Smad-dependent collagen gene induction in mesenchymal cells. J Biol Chem. 2004 Nov 12; 279(46):47455-63. PMID: 15345715.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    85. Sarcar B, Ghosh AK, Steele R, Ray R, Ray RB. Hepatitis C virus NS5A mediated STAT3 activation requires co-operation of Jak1 kinase. Virology. 2004 Apr 25; 322(1):51-60. PMID: 15063116.
      Citations: 23     Fields:    Translation:HumansCells
    86. Ray RB, Basu A, Steele R, Beyene A, McHowat J, Meyer K, Ghosh AK, Ray R. Ebola virus glycoprotein-mediated anoikis of primary human cardiac microvascular endothelial cells. Virology. 2004 Apr 10; 321(2):181-8. PMID: 15051379.
      Citations: 23     Fields:    Translation:HumansCells
    87. Ghosh AK, Bhattacharyya S, Lakos G, Chen SJ, Mori Y, Varga J. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma. Arthritis Rheum. 2004 Apr; 50(4):1305-18. PMID: 15077315.
      Citations: 83     Fields:    Translation:HumansCells
    88. Majumder M, Steele R, Ghosh AK, Zhou XY, Thornburg L, Ray R, Phillips NJ, Ray RB. Expression of hepatitis C virus non-structural 5A protein in the liver of transgenic mice. FEBS Lett. 2003 Dec 18; 555(3):528-32. PMID: 14675768.
      Citations: 21     Fields:    Translation:Animals
    89. Sen A, Steele R, Ghosh AK, Basu A, Ray R, Ray RB. Inhibition of hepatitis C virus protein expression by RNA interference. Virus Res. 2003 Oct; 96(1-2):27-35. PMID: 12951263.
      Citations: 19     Fields:    Translation:HumansCells
    90. Ghosh AK, Steele R, Ray RB. Modulation of human luteinizing hormone beta gene transcription by MIP-2A. J Biol Chem. 2003 Jun 27; 278(26):24033-8. PMID: 12700240.
      Citations: 5     Fields:    Translation:HumansCells
    91. Mukherjee P, Ghosh AK, Ghose AC. Infection pattern and immune response in the spleen and liver of BALB/c mice intracardially infected with Leishmania donovani amastigotes. Immunol Lett. 2003 Apr 03; 86(2):131-8. PMID: 12644314.
      Citations: 18     Fields:    Translation:AnimalsCells
    92. Ghosh AK, Majumder M, Steele R, Ray R, Ray RB. Modulation of interferon expression by hepatitis C virus NS5A protein and human homeodomain protein PTX1. Virology. 2003 Feb 01; 306(1):51-9. PMID: 12620797.
      Citations: 6     Fields:    Translation:HumansCells
    93. Ray RB, Steele R, Basu A, Meyer K, Majumder M, Ghosh AK, Ray R. Distinct functional role of Hepatitis C virus core protein on NF-kappaB regulation is linked to genomic variation. Virus Res. 2002 Jul; 87(1):21-9. PMID: 12135786.
      Citations: 12     Fields:    Translation:HumansCells
    94. Ghosh AK. Factors involved in the regulation of type I collagen gene expression: implication in fibrosis. Exp Biol Med (Maywood). 2002 May; 227(5):301-14. PMID: 11976400.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    95. Ghosh AK, Majumder M, Steele R, Liu TJ, Ray RB. MBP-1 mediated apoptosis involves cytochrome c release from mitochondria. Oncogene. 2002 Apr 25; 21(18):2775-84. PMID: 11973636.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    96. Majumder M, Ghosh AK, Steele R, Zhou XY, Phillips NJ, Ray R, Ray RB. Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice. Virology. 2002 Mar 01; 294(1):94-105. PMID: 11886269.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
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