Plasminogen Activator Inhibitor 1
"Plasminogen Activator Inhibitor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
| Descriptor ID |
D017395
|
| MeSH Number(s) |
D12.644.861.695.500 D12.776.124.125.640 D12.776.872.695.500 D23.119.832.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Plasminogen Activator Inhibitor 1".
Below are MeSH descriptors whose meaning is more specific than "Plasminogen Activator Inhibitor 1".
This graph shows the total number of publications written about "Plasminogen Activator Inhibitor 1" by people in this website by year, and whether "Plasminogen Activator Inhibitor 1" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 2 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 3 | 1 | 4 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Plasminogen Activator Inhibitor 1" by people in Profiles.
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Cardiomyocyte PAI-1 influences the cardiac transcriptome and limits the extent of cardiac fibrosis in response to left ventricular pressure overload. Cell Signal. 2023 04; 104:110555.
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Pharmacological inhibition of PAI-1 alleviates cardiopulmonary pathologies induced by exposure to air pollutants PM2.5. Environ Pollut. 2021 Oct 15; 287:117283.
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Estimated glucose disposal rate as a candidate biomarker for thrombotic biomarkers in T1D: a pooled analysis. J Endocrinol Invest. 2021 Nov; 44(11):2417-2426.
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PAI-1 contributes to homocysteine-induced cellular senescence. Cell Signal. 2019 12; 64:109394.
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The procoagulant molecule plasminogen activator inhibitor-1 is associated with injury severity and shock in patients with and without traumatic brain injury. J Trauma Acute Care Surg. 2018 11; 85(5):888-893.
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Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-ß and Cardiac Fibrosis. Circulation. 2017 Aug 15; 136(7):664-679.
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Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence. Arterioscler Thromb Vasc Biol. 2017 08; 37(8):1446-1452.
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Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-SIRT1 pathway. Aging Cell. 2017 08; 16(4):837-846.
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Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ. Breast Cancer Res. 2017 05 15; 19(1):56.
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Effect of ezetimibe on plasma adipokines: a systematic review and meta-analysis. Br J Clin Pharmacol. 2017 07; 83(7):1380-1396.