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Geoffrey Wool

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentPathology
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    I am a clinical pathologist with interests in Coagulation, Hematopathology, and Transfusion medicine/apheresis.
    My research interests involve thrombophilic microparticles, autoimmune thrombotic/bleeding disorders, and platelet immunology.


    Collapse Biography 
    Collapse education and training
    University of Chicago, Chicago06/2015Transfusion medicine fellowship
    UCSF, San Francisco06/2014Hematopathology fellowship
    UCSF, San Francsico06/2013Clinical pathology residency
    University of Chicago, ChicagoMD06/2010
    University of Chicago, ChicagoPhD09/2008Pathology
    UC Berkeley, BerkeleyBA05/2002Molecular/Cell Biology, History

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Fuja C, Kothary V, Carll TC, Singh S, Mansfield P, Wool GD. Hyperhemolysis in a patient with sickle cell disease and recent SARS-CoV-2 infection, with complex auto- and alloantibody work-up, successfully treated with tocilizumab. Transfusion. 2022 Jul; 62(7):1446-1451. PMID: 35588309.
      View in: PubMed
    2. Carll T, Mei Z, Aldarweesh F, Wool GD. Alloimmunization rates in transfused patients receiving anti-CD47 antibody therapy. Transfusion. 2022 04; 62(4):916-918. PMID: 35383955.
      View in: PubMed
    3. Carll T, Aldarweesh F, Christenson C, Wool GD. The Effect of RBC Transfusion on Oxygenation Status. Am J Clin Pathol. 2022 03 03; 157(3):477. PMID: 34596218.
      View in: PubMed
    4. Kanack AJ, Singh B, George G, Gundabolu K, Koepsell SA, Abou-Ismail MY, Moser KA, Smock KJ, Green D, Major A, Chan CW, Wool GD, Reding M, Ashrani AA, Bayas A, Grill DE, Padmanabhan A. Persistence of Ad26.COV2.S-associated vaccine-induced immune thrombotic thrombocytopenia (VITT) and specific detection of VITT antibodies. Am J Hematol. 2022 05; 97(5):519-526. PMID: 35132672.
      View in: PubMed
    5. Hendley SA, Bhargava A, Holland CK, Wool GD, Ahmed O, Paul JD, Bader KB. (More than) doubling down: Effective fibrinolysis at a reduced rt-PA dose for catheter-directed thrombolysis combined with histotripsy. PLoS One. 2022; 17(1):e0261567. PMID: 34982784.
      View in: PubMed
    6. Volod O, Rollins-Raval M, Goodwin AJ, Higgins RA, Long T, Chandler WL, Harris NS, Pham HP, Isom JA, Moser K, Olson JD, Smock KJ, VanSandt A, Wool G, Chen D. Interlaboratory Performance in Measurement of Dabigatran and Rivaroxaban. Arch Pathol Lab Med. 2022 01 02; 146(2):145-153. PMID: 34133726.
      View in: PubMed
    7. Hendley SA, Dimov A, Bhargava A, Snoddy E, Mansour D, Afifi RO, Wool GD, Zha Y, Sammet S, Lu ZF, Ahmed O, Paul JD, Bader KB. Assessment of histological characteristics, imaging markers, and rt-PA susceptibility of ex vivo venous thrombi. Sci Rep. 2021 11 23; 11(1):22805. PMID: 34815441.
      View in: PubMed
    8. Major A, Carll T, Chan CW, Christenson C, Aldarweesh F, Wool GD, Cohen KS. Refractory vaccine-induced immune thrombotic thrombocytopenia (VITT) managed with delayed therapeutic plasma exchange (TPE). J Clin Apher. 2022 Feb; 37(1):117-121. PMID: 34672380.
      View in: PubMed
    9. Pham HP, Azad A, Gounlong J, Gutierrez J, Mikrut K, Miller JL, Wool GD. Comparison of Viscoelastic Testing by Rotational Torsion and Harmonic Resonance Methods. Am J Clin Pathol. 2021 Oct 13; 156(5):818-828. PMID: 33978149.
      View in: PubMed
    10. Cho JH, Wool GD, Tjota MY, Gutierrez J, Mikrut K, Miller JL. Functional Assessment of Platelet Dense Granule ATP Release. Am J Clin Pathol. 2021 05 18; 155(6):863-872. PMID: 33386737.
      View in: PubMed
    11. Amin N, Cho JH, McMullen P, Uraizee I, Wool G, Su L. Platelet-rich aggregates in MNC collection circuit. Transfusion. 2021 04; 61(4):1010-1011. PMID: 33660852.
      View in: PubMed
    12. Madariaga MLL, Guthmiller JJ, Schrantz S, Jansen MO, Christensen C, Kumar M, Prochaska M, Wool G, Durkin-Celauro A, Oh WH, Trockman L, Vigneswaran J, Keskey R, Shaw DG, Dugan H, Zheng NY, Cobb M, Utset H, Wang J, Stovicek O, Bethel C, Matushek S, Giurcanu M, Beavis KG, di Sabato D, Meltzer D, Ferguson MK, Kress JP, Shanmugarajah K, Matthews JB, Fung JF, Wilson PC, Alverdy JC, Donington JS. Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID-19 convalescent plasma clinical trial. J Intern Med. 2021 04; 289(4):559-573. PMID: 33034095.
      View in: PubMed
    13. Wool GD, Miller JL. The Impact of COVID-19 Disease on Platelets and Coagulation. Pathobiology. 2021; 88(1):15-27. PMID: 33049751.
      View in: PubMed
    14. Carll T, Wool GD. Basic principles of viscoelastic testing. Transfusion. 2020 10; 60 Suppl 6:S1-S9. PMID: 33089939.
      View in: PubMed
    15. Anderson I, Wool GD, Madden W. Confirming Point-of-Care INR Test Results-Reply. JAMA. 2020 03 24; 323(12):1191-1192. PMID: 32207790.
      View in: PubMed
    16. Anderson I, Wool GD, Madden W. The Point-of-Care INR Test for Vitamin K Antagonist Monitoring. JAMA. 2019 12 03; 322(21):2129-2130. PMID: 31603458.
      View in: PubMed
    17. Deucher A, Wool GD. How I investigate bone marrow necrosis. Int J Lab Hematol. 2019 Oct; 41(5):585-592. PMID: 31424633.
      View in: PubMed
    18. Misra MK, Xin JJ, Brown NK, Weidner JG, Upchurch RL, Bishop MR, Wool GD, Artz AS, Marino SR. Effective desensitization for a strong donor-specific HLA antibody in a case of HLA-mismatched allogeneic hematopoietic cell transplantation. HLA. 2019 09; 94(3):307-311. PMID: 31314169.
      View in: PubMed
    19. Mei Z, Wool GD. Impact of Novel Monoclonal Antibody Therapeutics on Blood Bank Pretransfusion Testing. Hematol Oncol Clin North Am. 2019 10; 33(5):797-811. PMID: 31466605.
      View in: PubMed
    20. Wool GD. Benefits and Pitfalls of Point-of-Care Coagulation Testing for Anticoagulation Management: An ACLPS Critical Review. Am J Clin Pathol. 2019 01 01; 151(1):1-17. PMID: 30215666.
      View in: PubMed
    21. Cho JH, Parilla M, Treml A, Wool GD. Plasma exchange for heparin-induced thrombocytopenia in patients on extracorporeal circuits: A challenging case and a survey of the field. J Clin Apher. 2019 Feb; 34(1):64-72. PMID: 30407650.
      View in: PubMed
    22. Biller E, Zhao Y, Berg M, Boggio L, Capocelli KE, Fang DC, Koepsell S, Music-Aplenc L, Pham HP, Treml A, Weiss J, Wool G, Baron BW. Red blood cell exchange in patients with sickle cell disease-indications and management: a review and consensus report by the therapeutic apheresis subsection of the AABB. Transfusion. 2018 08; 58(8):1965-1972. PMID: 30198607.
      View in: PubMed
    23. Shunkwiler SM, Pham HP, Wool G, Ipe TS, Fang DC, Biller E, Treml A, Weiss J, Baron BW, Berg M. The management of anticoagulation in patients undergoing therapeutic plasma exchange: A concise review. J Clin Apher. 2018 Jun; 33(3):371-379. PMID: 29071747.
      View in: PubMed
    24. Wentworth KL, Bigay K, Chan TV, Ho JP, Morales BM, Connor J, Brooks E, Shahriar Salamat M, Sanchez HC, Wool G, Pignolo RJ, Kaplan FS, Hsiao EC. Clinical-pathological correlations in three patients with fibrodysplasia ossificans progressiva. Bone. 2018 04; 109:104-110. PMID: 29033382.
      View in: PubMed
    25. Wool GD, Treml A, Miller JL. Acquired factor XI deficiency and therapeutic plasma exchange. J Clin Apher. 2018 Jun; 33(3):427-430. PMID: 29027258.
      View in: PubMed
    26. Wool GD, Chapel D, Treml A, Miller JL. Therapeutic plasma exchange as part of multimodal treatment of acquired hemophilia in a patient with concurrent acute intracerebral bleed and pulmonary embolism. Transfusion. 2017 07; 57(7):1827-1832. PMID: 28436106.
      View in: PubMed
    27. Fidai S, Baron B, Treml A, Wool G. Daratumumab and Red Cell Serologic Testing: A Single-Institution Experience. Am J Clin Pathol. 2017 Mar 01; 147(suppl_2):S174-S175. PMID: 28339867.
      View in: PubMed
    28. Wool G. The Hidden Lesion. N Engl J Med. 2016 09 22; 375(12):1198-9. PMID: 27653585.
      View in: PubMed
    29. Balassanian R, Wool GD, Ono JC, Olejnik-Nave J, Mah MM, Sweeney BJ, Liberman H, Ljung BM, Pitman MB. A superior method for cell block preparation for fine-needle aspiration biopsies. Cancer Cytopathol. 2016 Jul; 124(7):508-18. PMID: 27105161.
      View in: PubMed
    30. Wool GD, Deucher A. Bone marrow necrosis: ten-year retrospective review of bone marrow biopsy specimens. Am J Clin Pathol. 2015 Feb; 143(2):201-13; quiz 306. PMID: 25596246.
      View in: PubMed
    31. Wool GD, Reardon CA, Getz GS. Mimetic peptides of human apoA-I helix 10 get together to lower lipids and ameliorate atherosclerosis: is the action in the gut? J Lipid Res. 2014 Oct; 55(10):1983-5. PMID: 25085258.
      View in: PubMed
    32. Wool GD, Lu CM. Pathology consultation on anticoagulation monitoring: factor X-related assays. Am J Clin Pathol. 2013 Nov; 140(5):623-34. PMID: 24124140.
      View in: PubMed
    33. Wool GD, Cabana VG, Lukens J, Shaw PX, Binder CJ, Witztum JL, Reardon CA, Getz GS. 4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E-null mice. FASEB J. 2011 Jan; 25(1):290-300. PMID: 20876212.
      View in: PubMed
    34. Getz GS, Wool GD, Reardon CA. Biological properties of apolipoprotein a-I mimetic peptides. Curr Atheroscler Rep. 2010 Mar; 12(2):96-104. PMID: 20425244.
      View in: PubMed
    35. Getz GS, Wool GD, Reardon CA. HDL apolipoprotein-related peptides in the treatment of atherosclerosis and other inflammatory disorders. Curr Pharm Des. 2010; 16(28):3173-84. PMID: 20687877.
      View in: PubMed
    36. Getz GS, Wool GD, Reardon CA. Apoprotein A-I mimetic peptides and their potential anti-atherogenic mechanisms of action. Curr Opin Lipidol. 2009 Jun; 20(3):171-5. PMID: 19373084.
      View in: PubMed
    37. Wool GD, Vaisar T, Reardon CA, Getz GS. An apoA-I mimetic peptide containing a proline residue has greater in vivo HDL binding and anti-inflammatory ability than the 4F peptide. J Lipid Res. 2009 Sep; 50(9):1889-900. PMID: 19433476.
      View in: PubMed
    38. Wool GD, Reardon CA, Getz GS. Apolipoprotein A-I mimetic peptide helix number and helix linker influence potentially anti-atherogenic properties. J Lipid Res. 2008 Jun; 49(6):1268-83. PMID: 18323574.
      View in: PubMed
    39. Wool GD, Reardon CA. The influence of acute phase proteins on murine atherosclerosis. Curr Drug Targets. 2007 Nov; 8(11):1203-14. PMID: 18045099.
      View in: PubMed
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