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Geoffrey Wool

TitleAssociate Professor
InstitutionUniversity of Chicago
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    I am a clinical pathologist with interests in Coagulation, Hematopathology, and Transfusion medicine/apheresis.
    My research interests involve thrombophilic microparticles, autoimmune thrombotic/bleeding disorders, and platelet immunology.

    Collapse Biography 
    Collapse education and training
    University of Chicago, Chicago06/2015Transfusion medicine fellowship
    UCSF, San Francisco06/2014Hematopathology fellowship
    UCSF, San Francsico06/2013Clinical pathology residency
    University of Chicago, ChicagoMD06/2010
    University of Chicago, ChicagoPhD09/2008Pathology
    UC Berkeley, BerkeleyBA05/2002Molecular/Cell Biology, History

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fuja C, Carll TC, Mikrut K, Wool GD. Sensitivity and specificity of thromboelastography for hyperfibrinolysis: Comparison of TEG 5000 and TEG 6S CK LY30 systems. Am J Clin Pathol. 2023 11 02; 160(5):455-465. PMID: 37415401.
      Citations:    Fields:    Translation:Humans
    2. Wool GD, Carll T. Viscoelastic testing: Critical appraisal of new methodologies and current literature. Int J Lab Hematol. 2023 Oct; 45(5):643-658. PMID: 37559473.
      Citations: 1     Fields:    Translation:Humans
    3. Sarkar A, Khandelwal S, Koma GT, Kim H, Gruel Y, Rollin J, Passam F, Wool GD, Arepally GM, Cines DB, Rauova L, Poncz M. Treatment of thrombocytopenia and thrombosis in HIT in mice using deglycosylated KKO: a novel therapeutic? Blood Adv. 2023 08 08; 7(15):4112-4123. PMID: 37196641; PMCID: PMC10388731.
      Citations:    Fields:    Translation:HumansAnimals
    4. Roloff GW, Wen F, Ramsland A, Artz AS, Kosuri S, Stock W, Odenike O, Larson RA, Liu H, Godley LA, Thirman MJ, Patel AA, Daugherty CK, DuVall AS, Nawas MT, Dworkin E, Wool GD, Gurbuxani S, Fitzpatrick C, Segal JP, Wang P, Drazer MW. Clinical and molecular response of acute myeloid leukemia harboring non-canonical FLT3 N676K driver mutations to contemporary FLT3 inhibitors. Haematologica. 2023 08 01; 108(8):2234-2239. PMID: 36655425; PMCID: PMC10388285.
      Citations:    Fields:    Translation:Humans
    5. Kanack AJ, Jones CG, Singh B, Leger RR, Splinter NP, Heikal NM, Pruthi RK, Chen D, George G, Abou-Ismail MY, Wool GD, Gundabolu K, Padmanabhan A. Off-the-shelf cryopreserved platelets for the detection of HIT and VITT antibodies. Blood. 2022 12 22; 140(25):2722-2729. PMID: 35998675; PMCID: PMC9837435.
      Citations: 4     Fields:    Translation:HumansCells
    6. Johnson B, Bucio J, Salerno C, Jeevanandam V, Song T, Wool G. Decreasing blood wastage during ex vivo lung perfusion recovery through utilization of thermal control technology. J Card Surg. 2022 Dec; 37(12):5011-5018. PMID: 36349705; PMCID: PMC10099649.
      Citations: 1     Fields:    Translation:Humans
    7. Salazar E, Long TA, Smock KJ, Wool GD, Rollins-Raval M, Chen D, Harris NS, Chan CW, Olson JD, Pham HP, Ritter J, Unold D, VanSandt AM, Goodwin Iv AJ. Analysis of College of American Pathologists von Willebrand Factor Proficiency Testing Program. Semin Thromb Hemost. 2022 Sep; 48(6):690-699. PMID: 36223772.
      Citations: 2     Fields:    Translation:Humans
    8. Salazar E, Long TA, Smock KJ, Wool GD, Rollins-Raval M, Chen D, Harris NS, Chan CW, Olson JD, Pham HP, Ritter J, Unold D, VanSandt AM, Goodwin Iv AJ. Analysis of College of American Pathologists von Willebrand Factor Proficiency Testing Program. Semin Thromb Hemost. 2022 Sep 02. PMID: 36055272.
      Citations:    Fields:    
    9. Fuja C, Kothary V, Carll TC, Singh S, Mansfield P, Wool GD. Hyperhemolysis in a patient with sickle cell disease and recent SARS-CoV-2 infection, with complex auto- and alloantibody work-up, successfully treated with tocilizumab. Transfusion. 2022 07; 62(7):1446-1451. PMID: 35588309; PMCID: PMC9347625.
      Citations: 4     Fields:    Translation:HumansCells
    10. Carll T, Mei Z, Aldarweesh F, Wool GD. Alloimmunization rates in transfused patients receiving anti-CD47 antibody therapy. Transfusion. 2022 04; 62(4):916-918. PMID: 35383955.
      Citations:    Fields:    Translation:HumansCells
    11. Carll T, Aldarweesh F, Christenson C, Wool GD. The Effect of RBC Transfusion on Oxygenation Status. Am J Clin Pathol. 2022 03 03; 157(3):477. PMID: 34596218.
      Citations:    Fields:    Translation:Humans
    12. Kanack AJ, Singh B, George G, Gundabolu K, Koepsell SA, Abou-Ismail MY, Moser KA, Smock KJ, Green D, Major A, Chan CW, Wool GD, Reding M, Ashrani AA, Bayas A, Grill DE, Padmanabhan A. Persistence of Ad26.COV2.S-associated vaccine-induced immune thrombotic thrombocytopenia (VITT) and specific detection of VITT antibodies. Am J Hematol. 2022 05; 97(5):519-526. PMID: 35132672; PMCID: PMC8986571.
      Citations: 13     Fields:    Translation:Humans
    13. Hendley SA, Bhargava A, Holland CK, Wool GD, Ahmed O, Paul JD, Bader KB. (More than) doubling down: Effective fibrinolysis at a reduced rt-PA dose for catheter-directed thrombolysis combined with histotripsy. PLoS One. 2022; 17(1):e0261567. PMID: 34982784; PMCID: PMC8726487.
      Citations: 2     Fields:    Translation:HumansCells
    14. Volod O, Rollins-Raval M, Goodwin AJ, Higgins RA, Long T, Chandler WL, Harris NS, Pham HP, Isom JA, Moser K, Olson JD, Smock KJ, VanSandt A, Wool G, Chen D. Interlaboratory Performance in Measurement of Dabigatran and Rivaroxaban. Arch Pathol Lab Med. 2022 01 02; 146(2):145-153. PMID: 34133726.
      Citations: 1     Fields:    Translation:Humans
    15. Hendley SA, Dimov A, Bhargava A, Snoddy E, Mansour D, Afifi RO, Wool GD, Zha Y, Sammet S, Lu ZF, Ahmed O, Paul JD, Bader KB. Assessment of histological characteristics, imaging markers, and rt-PA susceptibility of ex vivo venous thrombi. Sci Rep. 2021 11 23; 11(1):22805. PMID: 34815441; PMCID: PMC8610976.
      Citations: 3     Fields:    Translation:Humans
    16. Major A, Carll T, Chan CW, Christenson C, Aldarweesh F, Wool GD, Cohen KS. Refractory vaccine-induced immune thrombotic thrombocytopenia (VITT) managed with delayed therapeutic plasma exchange (TPE). J Clin Apher. 2022 Feb; 37(1):117-121. PMID: 34672380.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    17. Pham HP, Azad A, Gounlong J, Gutierrez J, Mikrut K, Miller JL, Wool GD. Comparison of Viscoelastic Testing by Rotational Torsion and Harmonic Resonance Methods. Am J Clin Pathol. 2021 Oct 13; 156(5):818-828. PMID: 33978149.
      Citations: 2     Fields:    Translation:Humans
    18. Cho JH, Wool GD, Tjota MY, Gutierrez J, Mikrut K, Miller JL. Functional Assessment of Platelet Dense Granule ATP Release. Am J Clin Pathol. 2021 05 18; 155(6):863-872. PMID: 33386737.
      Citations: 1     Fields:    Translation:HumansCells
    19. Amin N, Cho JH, McMullen P, Uraizee I, Wool G, Su L. Platelet-rich aggregates in MNC collection circuit. Transfusion. 2021 04; 61(4):1010-1011. PMID: 33660852.
      Citations:    Fields:    Translation:HumansCells
    20. Madariaga MLL, Guthmiller JJ, Schrantz S, Jansen MO, Christensen C, Kumar M, Prochaska M, Wool G, Durkin-Celauro A, Oh WH, Trockman L, Vigneswaran J, Keskey R, Shaw DG, Dugan H, Zheng NY, Cobb M, Utset H, Wang J, Stovicek O, Bethel C, Matushek S, Giurcanu M, Beavis KG, di Sabato D, Meltzer D, Ferguson MK, Kress JP, Shanmugarajah K, Matthews JB, Fung JF, Wilson PC, Alverdy JC, Donington JS. Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID-19 convalescent plasma clinical trial. J Intern Med. 2021 04; 289(4):559-573. PMID: 33034095; PMCID: PMC7675325.
      Citations: 39     Fields:    Translation:HumansCellsCTClinical Trials
    21. Wool GD, Miller JL. The Impact of COVID-19 Disease on Platelets and Coagulation. Pathobiology. 2021; 88(1):15-27. PMID: 33049751; PMCID: PMC7649697.
      Citations: 196     Fields:    Translation:HumansCells
    22. Carll T, Wool GD. Basic principles of viscoelastic testing. Transfusion. 2020 10; 60 Suppl 6:S1-S9. PMID: 33089939.
      Citations: 15     Fields:    Translation:HumansCellsPHPublic Health
    23. Anderson I, Wool GD, Madden W. Confirming Point-of-Care INR Test Results-Reply. JAMA. 2020 03 24; 323(12):1191-1192. PMID: 32207790.
      Citations:    Fields:    
    24. Anderson I, Wool GD, Madden W. The Point-of-Care INR Test for Vitamin K Antagonist Monitoring. JAMA. 2019 12 03; 322(21):2129-2130. PMID: 31603458.
      Citations:    Fields:    Translation:Humans
    25. Deucher A, Wool GD. How I investigate bone marrow necrosis. Int J Lab Hematol. 2019 Oct; 41(5):585-592. PMID: 31424633.
      Citations: 5     Fields:    Translation:Humans
    26. Misra MK, Xin JJ, Brown NK, Weidner JG, Upchurch RL, Bishop MR, Wool GD, Artz AS, Marino SR. Effective desensitization for a strong donor-specific HLA antibody in a case of HLA-mismatched allogeneic hematopoietic cell transplantation. HLA. 2019 09; 94(3):307-311. PMID: 31314169.
      Citations: 1     Fields:    Translation:Humans
    27. Mei Z, Wool GD. Impact of Novel Monoclonal Antibody Therapeutics on Blood Bank Pretransfusion Testing. Hematol Oncol Clin North Am. 2019 10; 33(5):797-811. PMID: 31466605.
      Citations:    Fields:    Translation:Humans
    28. Wool GD. Benefits and Pitfalls of Point-of-Care Coagulation Testing for Anticoagulation Management: An ACLPS Critical Review. Am J Clin Pathol. 2019 01 01; 151(1):1-17. PMID: 30215666.
      Citations: 11     Fields:    Translation:Humans
    29. Cho JH, Parilla M, Treml A, Wool GD. Plasma exchange for heparin-induced thrombocytopenia in patients on extracorporeal circuits: A challenging case and a survey of the field. J Clin Apher. 2019 Feb; 34(1):64-72. PMID: 30407650.
      Citations: 3     Fields:    Translation:Humans
    30. Jacquot C, Wool GD, Kogan SC. Dilute Russell viper venom time interpretation and clinical correlation: A two-year retrospective institutional review. Int J Lab Hematol. 2019 Feb; 41(1):80-86. PMID: 30194751.
      Citations: 1     Fields:    Translation:Humans
    31. Biller E, Zhao Y, Berg M, Boggio L, Capocelli KE, Fang DC, Koepsell S, Music-Aplenc L, Pham HP, Treml A, Weiss J, Wool G, Baron BW. Red blood cell exchange in patients with sickle cell disease-indications and management: a review and consensus report by the therapeutic apheresis subsection of the AABB. Transfusion. 2018 08; 58(8):1965-1972. PMID: 30198607.
      Citations: 12     Fields:    Translation:Humans
    32. Shunkwiler SM, Pham HP, Wool G, Ipe TS, Fang DC, Biller E, Treml A, Weiss J, Baron BW, Berg M, Therapeutic Apheresis Subsection of the AABB. The management of anticoagulation in patients undergoing therapeutic plasma exchange: A concise review. J Clin Apher. 2018 Jun; 33(3):371-379. PMID: 29071747.
      Citations: 7     Fields:    Translation:Humans
    33. Wentworth KL, Bigay K, Chan TV, Ho JP, Morales BM, Connor J, Brooks E, Shahriar Salamat M, Sanchez HC, Wool G, Pignolo RJ, Kaplan FS, Hsiao EC. Clinical-pathological correlations in three patients with fibrodysplasia ossificans progressiva. Bone. 2018 04; 109:104-110. PMID: 29033382.
      Citations: 9     Fields:    Translation:Humans
    34. Wool GD, Treml A, Miller JL. Acquired factor XI deficiency and therapeutic plasma exchange. J Clin Apher. 2018 Jun; 33(3):427-430. PMID: 29027258.
      Citations: 2     Fields:    Translation:Humans
    35. Wool GD, Chapel D, Treml A, Miller JL. Therapeutic plasma exchange as part of multimodal treatment of acquired hemophilia in a patient with concurrent acute intracerebral bleed and pulmonary embolism. Transfusion. 2017 07; 57(7):1827-1832. PMID: 28436106.
      Citations: 2     Fields:    Translation:Humans
    36. Fidai S, Baron B, Treml A, Wool G. Daratumumab and Red Cell Serologic Testing: A Single-Institution Experience. Am J Clin Pathol. 2017 Mar 01; 147(suppl_2):S174-S175. PMID: 28339867.
    37. Wool G. The Hidden Lesion. N Engl J Med. 2016 09 22; 375(12):1198-9. PMID: 27653585.
      Citations:    Fields:    
    38. Balassanian R, Wool GD, Ono JC, Olejnik-Nave J, Mah MM, Sweeney BJ, Liberman H, Ljung BM, Pitman MB. A superior method for cell block preparation for fine-needle aspiration biopsies. Cancer Cytopathol. 2016 Jul; 124(7):508-18. PMID: 27105161.
      Citations: 14     Fields:    Translation:Humans
    39. Wool GD, Deucher A. Bone marrow necrosis: ten-year retrospective review of bone marrow biopsy specimens. Am J Clin Pathol. 2015 Feb; 143(2):201-13; quiz 306. PMID: 25596246.
      Citations: 9     Fields:    Translation:Humans
    40. Wool GD, Reardon CA, Getz GS. Mimetic peptides of human apoA-I helix 10 get together to lower lipids and ameliorate atherosclerosis: is the action in the gut? J Lipid Res. 2014 Oct; 55(10):1983-5. PMID: 25085258; PMCID: PMC4173990.
      Citations: 7     Fields:    Translation:Animals
    41. Wool GD, Lu CM, Education Committee of the Academy of Clinical Laboratory Physicians and Scientists. Pathology consultation on anticoagulation monitoring: factor X-related assays. Am J Clin Pathol. 2013 Nov; 140(5):623-34. PMID: 24124140.
      Citations: 6     Fields:    Translation:Humans
    42. Wool GD, Cabana VG, Lukens J, Shaw PX, Binder CJ, Witztum JL, Reardon CA, Getz GS. 4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E-null mice. FASEB J. 2011 Jan; 25(1):290-300. PMID: 20876212; PMCID: PMC3005429.
      Citations: 25     Fields:    Translation:AnimalsCells
    43. Getz GS, Wool GD, Reardon CA. Biological properties of apolipoprotein a-I mimetic peptides. Curr Atheroscler Rep. 2010 Mar; 12(2):96-104. PMID: 20425244; PMCID: PMC3087815.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    44. Getz GS, Wool GD, Reardon CA. HDL apolipoprotein-related peptides in the treatment of atherosclerosis and other inflammatory disorders. Curr Pharm Des. 2010; 16(28):3173-84. PMID: 20687877; PMCID: PMC3087816.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    45. Getz GS, Wool GD, Reardon CA. Apoprotein A-I mimetic peptides and their potential anti-atherogenic mechanisms of action. Curr Opin Lipidol. 2009 Jun; 20(3):171-5. PMID: 19373084.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    46. Wool GD, Vaisar T, Reardon CA, Getz GS. An apoA-I mimetic peptide containing a proline residue has greater in vivo HDL binding and anti-inflammatory ability than the 4F peptide. J Lipid Res. 2009 Sep; 50(9):1889-900. PMID: 19433476; PMCID: PMC2724789.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    47. Wool GD, Reardon CA, Getz GS. Apolipoprotein A-I mimetic peptide helix number and helix linker influence potentially anti-atherogenic properties. J Lipid Res. 2008 Jun; 49(6):1268-83. PMID: 18323574; PMCID: PMC3837452.
      Citations: 35     Fields:    Translation:AnimalsCells
    48. Wool GD, Reardon CA. The influence of acute phase proteins on murine atherosclerosis. Curr Drug Targets. 2007 Nov; 8(11):1203-14. PMID: 18045099.
      Citations: 5     Fields:    Translation:HumansAnimals
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