A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities.

A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities. Cell Physiol Biochem. 2016; 39(3):871-88.

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subject areas

Animals
Antineoplastic Agents
Antineoplastic Combined Chemotherapy Protocols
Antiparasitic Agents
Apoptosis
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Cell Cycle
Cell Line, Tumor
Cell Movement
Cell Proliferation
Drug Repositioning
ets-Domain Protein Elk-1
Female
Gene Expression Regulation, Neoplastic
HEK293 Cells
Humans
Insulin-Like Growth Factor I
Mice
NF-kappa B
Niclosamide
Ovarian Neoplasms
Receptor, IGF Type 1
Repressor Proteins
RNA, Small Interfering
Signal Transduction
Transcription Factor AP-1
Xenograft Model Antitumor Assays

authors with profiles

Hue H. Luu
Rex C. Haydon
Tong-Chuan He