"Sapogenins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The aglucon moiety of a saponin molecule. It may be triterpenoid or steroid, usually spirostan, in nature.
| Descriptor ID |
D012502
|
| MeSH Number(s) |
D02.455.849.919.650 D04.210.500.795
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sapogenins".
Below are MeSH descriptors whose meaning is more specific than "Sapogenins".
This graph shows the total number of publications written about "Sapogenins" by people in this website by year, and whether "Sapogenins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sapogenins" by people in Profiles.
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Ginseng metabolite Protopanaxadiol induces Sestrin2 expression and AMPK activation through GCN2 and PERK. Cell Death Dis. 2019 04 05; 10(4):311.
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Ginseng metabolite protopanaxadiol interferes with lipid metabolism and induces endoplasmic reticulum stress and p53 activation to promote cancer cell death. Phytother Res. 2019 Mar; 33(3):610-617.
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Design and synthesis of 28-hydroxy protopanaxadiol as a novel probe template. Nat Prod Res. 2017 Jul; 31(13):1523-1528.
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Phytochemistry and Anticancer Potential of Notoginseng. Am J Chin Med. 2016; 44(1):23-34.
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Protopanaxadiol, an active ginseng metabolite, significantly enhances the effects of fluorouracil on colon cancer. Nutrients. 2015 Jan 23; 7(2):799-814.
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TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol. J Pharmacol Sci. 2015 Jan; 127(1):83-91.
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Natural products and chemotherapeutic agents on cancer: prevention vs. treatment. Am J Chin Med. 2014; 42(6):1555-8.
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Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways. Oncol Rep. 2013 Jul; 30(1):292-8.
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Paraptosis and NF-?B activation are associated with protopanaxadiol-induced cancer chemoprevention. BMC Complement Altern Med. 2013 Jan 03; 13:2.
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Synthesis of protopanaxadiol derivatives and evaluation of their anticancer activities. Anticancer Drugs. 2011 Jan; 22(1):35-45.