"Aldehyde-Lyases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze a reverse aldol condensation. A molecule containing a hydroxyl group and a carbonyl group is cleaved at a C-C bond to produce two smaller molecules (ALDEHYDES or KETONES). EC 4.1.2.
| Descriptor ID |
D000446
|
| MeSH Number(s) |
D08.811.520.224.062
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Aldehyde-Lyases".
Below are MeSH descriptors whose meaning is more specific than "Aldehyde-Lyases".
This graph shows the total number of publications written about "Aldehyde-Lyases" by people in this website by year, and whether "Aldehyde-Lyases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aldehyde-Lyases" by people in Profiles.
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Nuclear Sphingosine-1-phosphate Lyase Generated ?2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells. Cell Biochem Biophys. 2021 Sep; 79(3):575-592.
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S1P and plasmalogen derived fatty aldehydes in cellular signaling and functions. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 07; 1865(7):158681.
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Sphingolipids in Ventilator Induced Lung Injury: Role of Sphingosine-1-Phosphate Lyase. Int J Mol Sci. 2018 Jan 01; 19(1).
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Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase. Adv Biol Regul. 2017 Jan; 63:156-166.
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Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium. Am J Physiol Lung Cell Mol Physiol. 2016 08 01; 311(2):L337-51.
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Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy. Thorax. 2015 Dec; 70(12):1138-48.
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Inhibition of sphingosine-1-phosphate lyase rescues sphingosine kinase-1-knockout phenotype following murine cardiac arrest. Life Sci. 2013 Sep 17; 93(9-11):359-66.
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Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression. Am J Respir Cell Mol Biol. 2011 Aug; 45(2):426-35.
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A bacterial selection for the directed evolution of pyruvate aldolases. Bioorg Med Chem. 2004 Aug 01; 12(15):4067-74.
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Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. Structure. 2001 Jan 10; 9(1):1-9.