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Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody.
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Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody.
Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody. Sci Rep. 2017 04 03; 7(1):556.
View in:
PubMed
subject areas
Antibodies, Monoclonal
Catalysis
Cell Surface Display Techniques
Enzyme Activation
Enzyme Inhibitors
Humans
Isocitrate Dehydrogenase
Kinetics
Mutation
Peptide Library
Thermodynamics
authors with profiles
Anthony Kossiakoff
Somnath Mukherjee