"Apomorphine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.
| Descriptor ID |
D001058
|
| MeSH Number(s) |
D03.132.098.038.290 D03.633.100.531.085.030.290 D03.633.400.095.290
|
| Concept/Terms |
Apomorphine Hydrochloride, Anhydrous- Apomorphine Hydrochloride, Anhydrous
- Anhydrous Apomorphine Hydrochloride
- Hydrochloride, Anhydrous Apomorphine
- Apomorphine Hydrochloride Anhydrous
- Anhydrous, Apomorphine Hydrochloride
- Hydrochloride Anhydrous, Apomorphine
Apomorphine Hydrochloride- Apomorphine Hydrochloride
- Hydrochloride, Apomorphine
- Apomorphine Hydrochloride, Hemihydrate
- Hemihydrate Apomorphine Hydrochloride
- Hydrochloride, Hemihydrate Apomorphine
|
Below are MeSH descriptors whose meaning is more general than "Apomorphine".
Below are MeSH descriptors whose meaning is more specific than "Apomorphine".
This graph shows the total number of publications written about "Apomorphine" by people in this website by year, and whether "Apomorphine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apomorphine" by people in Profiles.
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Previous exposure to delta9-tetrahydrocannibinol enhances locomotor responding to but not self-administration of amphetamine. J Pharmacol Exp Ther. 2011 Jun; 337(3):724-33.
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Distinct temporal phases in the behavioral pharmacology of LSD: dopamine D2 receptor-mediated effects in the rat and implications for psychosis. Psychopharmacology (Berl). 2005 Jul; 180(3):427-35.
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Clinical efficacy of Apomorphine SL in erectile dysfunction of diabetic men. Int J Impot Res. 2005 Jan-Feb; 17(1):80-5.
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A double-blind, placebo-controlled study of intranasal apomorphine spray as a rescue agent for off-states in Parkinson's disease. Mov Disord. 1998 Sep; 13(5):782-7.
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Prevention of apomorphine- or cisplatin-induced emesis in the dog by a combination of methylnaltrexone and morphine. Cancer Chemother Pharmacol. 1998; 42(4):287-91.
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Intranasal apomorphine rescue therapy for parkinsonian "off" periods. Clin Neuropharmacol. 1996 Jun; 19(3):193-201.
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Psychopharmacology of prepulse inhibition in mice. Chin J Physiol. 1996; 39(3):139-46.
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Astrocytes retrovirally transduced with BDNF elicit behavioral improvement in a rat model of Parkinson's disease. Brain Res. 1995 Sep 11; 691(1-2):25-36.
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PET- and MRI-based assessment of glucose utilization, dopamine receptor binding, and hemodynamic changes after lesions to the caudate-putamen in primates. Exp Neurol. 1994 Jan; 125(1):41-51.
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Characterization of the rat mutant dystonic (dt): a new animal model of dystonia musculorum deformans. J Neurosci. 1984 Aug; 4(8):1925-32.