"Benzo(a)pyrene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
| Descriptor ID |
D001564
|
| MeSH Number(s) |
D02.455.426.559.847.799.306.300 D04.615.799.306.300
|
| Concept/Terms |
Benzo(a)pyrene- Benzo(a)pyrene
- 3,4-Benzpyrene
- 3,4 Benzpyrene
- 3,4-Benzopyrene
- 3,4 Benzopyrene
|
Below are MeSH descriptors whose meaning is more general than "Benzo(a)pyrene".
Below are MeSH descriptors whose meaning is more specific than "Benzo(a)pyrene".
This graph shows the total number of publications written about "Benzo(a)pyrene" by people in this website by year, and whether "Benzo(a)pyrene" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Benzo(a)pyrene" by people in Profiles.
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Altered expression of histone deacetylases, inflammatory cytokines and contractile-associated factors in uterine myometrium of Long Evans rats gestationally exposed to benzo[a]pyrene. J Appl Toxicol. 2016 Jun; 36(6):827-35.
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Catalytic and non-catalytic roles of DNA polymerase ? in the protection of human cells against genotoxic stresses. Environ Mol Mutagen. 2015 Oct; 56(8):650-62.
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Synthesis of phenol and quinone metabolites of benzo[a]pyrene, a carcinogenic component of tobacco smoke implicated in lung cancer. J Org Chem. 2009 Jan 16; 74(2):597-604.
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Efficient syntheses of C(8)-aryl adducts of adenine and guanine formed by reaction of radical cation metabolites of carcinogenic polycyclic aromatic hydrocarbons with DNA. J Org Chem. 2007 Jun 22; 72(13):4856-63.
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Induction of cytochrome CYPIA1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: a possible role in atherogenesis. Proc Natl Acad Sci U S A. 1994 Jun 07; 91(12):5397-401.
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Induction of rabbit hepatic microsomal cytochrome P-450 by imidazole: enhanced metabolic activity and altered substrate specificity. Arch Biochem Biophys. 1984 Dec; 235(2):470-81.