"Bicuculline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An isoquinoline alkaloid obtained from Dicentra cucullaria and other plants. It is a competitive antagonist for GABA-A receptors.
| Descriptor ID |
D001640
|
| MeSH Number(s) |
D03.132.098.077 D03.633.100.531.085.077
|
| Concept/Terms |
Bicuculline- Bicuculline
- 6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)furo(3,4-e)1,3-benzodioxol-8(6H)one
|
Below are MeSH descriptors whose meaning is more general than "Bicuculline".
Below are MeSH descriptors whose meaning is more specific than "Bicuculline".
This graph shows the total number of publications written about "Bicuculline" by people in this website by year, and whether "Bicuculline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 3 | 3 |
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Below are the most recent publications written about "Bicuculline" by people in Profiles.
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Hippocampal GABAA antagonism reverses the novel object recognition deficit in sub-chronic phencyclidine-treated rats. Behav Brain Res. 2018 04 16; 342:11-18.
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Neuronal bursting properties in focal and parafocal regions in pediatric neocortical epilepsy stratified by histology. J Clin Neurophysiol. 2010 Dec; 27(6):387-97.
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The modulatory effects of rostral ventromedial medulla on air-puff evoked microarousals in rats. Behav Brain Res. 2010 Dec 20; 215(1):156-9.
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Substance P modulation of TRPC3/7 channels improves respiratory rhythm regularity and ICAN-dependent pacemaker activity. Eur J Neurosci. 2010 Apr; 31(7):1219-32.
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Differential modulation of neural network and pacemaker activity underlying eupnea and sigh-breathing activities. J Neurophysiol. 2008 05; 99(5):2114-25.
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Enhanced nicotinic receptor function and drug abuse vulnerability. J Neurosci. 2007 Aug 15; 27(33):8771-8.
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Excitatory and inhibitory actions of isoflurane in bovine chromaffin cells. J Neurophysiol. 2006 Dec; 96(6):3042-50.
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Spike-timing-dependent plasticity of inhibitory synapses in the entorhinal cortex. J Neurophysiol. 2006 Dec; 96(6):3305-13.
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Modulation of sympathetic and somatomotor function by the ventromedial medulla. J Neurophysiol. 2004 Jul; 92(1):510-22.
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The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity. Anesth Analg. 2004 Feb; 98(2):353-358.