Cystathionine gamma-Lyase
"Cystathionine gamma-Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional pyridoxal phosphate enzyme. In the final step in the biosynthesis of cysteine it catalyzes the cleavage of cystathionine to yield cysteine, ammonia, and 2-ketobutyrate. EC 4.4.1.1.
| Descriptor ID |
D003542
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| MeSH Number(s) |
D08.811.520.300.250
|
| Concept/Terms |
Cystathionine gamma-Lyase- Cystathionine gamma-Lyase
- Cystathionine gamma Lyase
- gamma-Lyase, Cystathionine
- Cystine Desulfhydrase
- Desulfhydrase, Cystine
- Cysteine Desulfhydrase
- Desulfhydrase, Cysteine
- gamma-Cystathionase
- gamma Cystathionase
- Homoserine Deaminase
- Deaminase, Homoserine
- Homoserine Dehydratase
- Dehydratase, Homoserine
- Cystathionase
- Cystine Desulfohydrolase
- Desulfohydrolase, Cystine
|
Below are MeSH descriptors whose meaning is more general than "Cystathionine gamma-Lyase".
Below are MeSH descriptors whose meaning is more specific than "Cystathionine gamma-Lyase".
This graph shows the total number of publications written about "Cystathionine gamma-Lyase" by people in this website by year, and whether "Cystathionine gamma-Lyase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cystathionine gamma-Lyase" by people in Profiles.
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Gaseous transmitter regulation of hypoxia-evoked catecholamine secretion from murine adrenal chromaffin cells. J Neurophysiol. 2021 05 01; 125(5):1533-1542.
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H2S mediates carotid body response to hypoxia but not anoxia. Respir Physiol Neurobiol. 2019 01; 259:75-85.
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Therapeutic Targeting of the Carotid Body for Treating Sleep Apnea in a Pre-clinical Mouse Model. Adv Exp Med Biol. 2018; 1071:109-114.
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Complementary roles of gasotransmitters CO and H2S in sleep apnea. Proc Natl Acad Sci U S A. 2017 02 07; 114(6):1413-1418.
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H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea. Sci Signal. 2016 08 16; 9(441):ra80.
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Protein kinase G-regulated production of H2S governs oxygen sensing. Sci Signal. 2015 Apr 21; 8(373):ra37.
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CaV3.2 T-type Ca²? channels in H2S-mediated hypoxic response of the carotid body. Am J Physiol Cell Physiol. 2015 Jan 15; 308(2):C146-54.
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Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1174-9.
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Endogenous H2S is required for hypoxic sensing by carotid body glomus cells. Am J Physiol Cell Physiol. 2012 Nov 01; 303(9):C916-23.
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H2S mediates O2 sensing in the carotid body. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10719-24.