"Cytotoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
| Descriptor ID |
D003603
|
| MeSH Number(s) |
D27.888.569.213
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cytotoxins".
Below are MeSH descriptors whose meaning is more specific than "Cytotoxins".
This graph shows the total number of publications written about "Cytotoxins" by people in this website by year, and whether "Cytotoxins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 2 | 3 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Cytotoxins" by people in Profiles.
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Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria. Nat Commun. 2024 Jun 12; 15(1):5028.
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A basic model for the association of ligands with membrane cholesterol: application to cytolysin binding. J Lipid Res. 2023 04; 64(4):100344.
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A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins. J Bacteriol. 2022 05 17; 204(5):e0055521.
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Stimulation of the ATPase activity of Hsp90 by zerumbone modification of its cysteine residues destabilizes its clients and causes cytotoxicity. Biochem J. 2018 08 16; 475(15):2559-2576.
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Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules. Immunity. 2016 12 20; 45(6):1258-1269.
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Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin. Clin Vaccine Immunol. 2016 06; 23(6):442-50.
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Elevated double negative T cells in pediatric autoimmunity. J Clin Immunol. 2014 Jul; 34(5):594-9.
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[Design of next generation antibody drug conjugates]. Yao Xue Xue Bao. 2013 Jul; 48(7):1053-70.
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NCI-RTOG translational program strategic guidelines for the early-stage development of radiosensitizers. J Natl Cancer Inst. 2013 Jan 02; 105(1):11-24.
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Effects of MACPF/CDC proteins on lipid membranes. Cell Mol Life Sci. 2013 Jun; 70(12):2083-98.