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Christos Lazaridis

TitleProfessor
InstitutionUniversity of Chicago
DepartmentNeurology
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    A neurointensivist, Dr. Christos Lazaridis is interested in all aspects of care for critically ill neurological and neurosurgical patients; specific clinical and research interests include neuromonitoring and management of traumatic brain injury, and neurocritical care ethics. He enjoys teaching fellows, residents and medical students in general and neuro-critical care.

    Collapse Biography 
    Collapse education and training
    Pécs University Medical School, Pécs, HungaryMD08/2001Medicine
    University of Texas, Southwestern Medical School, Dallas, TX06/2006Neurology
    Johns Hopkins University, Baltimore, MD06/2008Neurocritical Care
    Cambridge University, Cambridge, UK01/2012Neurotrauma Critical Care (6mo)
    University of Toronto, Sunnybrook Hospital, Toronto, Canada05/2016Critical Care Medicine (6mo)
    Collapse awards and honors
    2011European Diploma in Intensive Care, European Society of Intensive Care Medicine

    Collapse Research 
    Collapse research activities and funding
    1U01NS099046-01A1     (Diaz-Arrastia)
    NIH
    Brain Oxygen Optimization in Severe TBI Phase-3
    Role Description: Randomized controlled trial testing the co-management of brain tissue oxygenation and intracranial pressure vs. ICP alone in severe TBI
    Role: Clinical PI for U of Chicago

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lazaridis C, Nowak PG, Lizza JP. Death and the Inescapability of Value Judgments. Chest. 2024 Sep; 166(3):e96-e97. PMID: 39260954.
      Citations:    Fields:    Translation:Humans
    2. Lizza JP, Lazaridis C, Nowak PG, Lazaridis C. Defining Death: Toward a Biological and Ethical Synthesis. Am J Bioeth. 2024 Jul 17; 1-12. PMID: 39018166.
      Citations:    Fields:    
    3. Lazaridis C. Brain death: Controversies and reappraisals. Clin Liver Dis (Hoboken). 2024 Jan-Jun; 23(1):e0168. PMID: 38872779; PMCID: PMC11168857.
      Citations:    
    4. Mansour A, Powla PP, Alvarado-Dyer R, Fakhri F, Das P, Horowitz P, Goldenberg FD, Lazaridis C. Comparative Analysis of Clinical Severity and Outcomes in Penetrating Versus Blunt Traumatic Brain Injury Propensity Matched Cohorts. Neurotrauma Rep. 2024; 5(1):348-358. PMID: 38595793; PMCID: PMC11002325.
      Citations:    
    5. Lazaridis C, Wolf M, Roth WH, Fan T, Mansour A, Goldenberg FD. Apnea Test: The Family in the Room. Neurocrit Care. 2024 Aug; 41(1):1-5. PMID: 38158482.
      Citations: 1     Fields:    Translation:Humans
    6. Morsi RZ, Baskaran A, Thind S, Carrión-Penagos J, Desai H, Kothari SA, Mirza M, Lazaridis C, Goldenberg F, Hurley MC, Mendelson SJ, Prabhakaran S, Zakrison T, Mansour A, Kass-Hout T. Endovascular Embolization of Traumatic Vessel Injury Using N-butyl Cyanoacrylate: A Case Series. Indian J Otolaryngol Head Neck Surg. 2024 Apr; 76(2):1554-1562. PMID: 38566650; PMCID: PMC10982176.
      Citations:    
    7. Lazaridis C. Resuscitation for Donation After Brain Death: Respecting Autonomy and Maximizing Utility. Crit Care Med. 2024 Sep 01; 52(9):1472-1475. PMID: 38059731.
      Citations:    Fields:    Translation:Humans
    8. Foreman B, Kapinos G, Wainwright MS, Ngwenya LB, O'Phelan KH, LaRovere KL, Kirschen MP, Appavu B, Lazaridis C, Alkhachroum A, Maciel CB, Amorim E, Chang JJ, Gilmore EJ, Rosenthal ES, Park S. Practice Standards for the Use of Multimodality Neuromonitoring: A Delphi Consensus Process. Crit Care Med. 2023 12 01; 51(12):1740-1753. PMID: 37607072; PMCID: PMC11036878.
      Citations: 1     Fields:    Translation:Humans
    9. Ciarrocchi N, Pose F, Videla CG, Del Carmen García M, Goldenberg FD, Lazaridis C, Issa NP, Redelico FO, Mansour A. Novel EEG Metric Correlates with Intracranial Pressure in an Animal Model. Neurocrit Care. 2024 Jun; 40(3):918-930. PMID: 37940837.
      Citations: 1     Fields:    Translation:Animals
    10. Mansour A, Powla PP, Fakhri F, Alvarado-Dyer R, Das P, Horowitz P, Goldenberg FD, Lazaridis C. Comparative Effectiveness of Early Neurosurgical Intervention in Civilian Penetrating Brain Injury Management. Neurosurgery. 2024 Mar 01; 94(3):470-477. PMID: 37847039.
      Citations:    Fields:    Translation:Humans
    11. Lazaridis C, Das P. Penetrating Firearm-Inflicted Injury-The Neglected Traumatic Brain Injury. JAMA Neurol. 2023 Oct 01; 80(10):1013-1014. PMID: 37669024.
      Citations:    Fields:    
    12. Lazaridis C. Cerebral blood flow after thoracoabdominal normothermic regional perfusion: Fundamental yet underexplored. J Heart Lung Transplant. 2023 12; 42(12):1764-1765. PMID: 37683893.
      Citations:    Fields:    Translation:Humans
    13. Tangonan R, Lazaridis C. Evaluation and Management of Disorders of Consciousness in the Acute Care Setting. Phys Med Rehabil Clin N Am. 2024 Feb; 35(1):79-92. PMID: 37993195.
      Citations:    Fields:    Translation:Humans
    14. Alvarado-Dyer R, Saleh Velez FG, Kamdar HA, Niznick N, Carroll E, Castillo-Pinto C, Parasram M, Kelly D, Goswami S, Ehntholt MS, Dangayach NS, Babi MA, Ramadan AR, Lazaridis C, Albin C, Morris NA. Curriculum Innovations: A Social Media-Based Educational Curriculum Improves Knowledge for Trainees in Neurocritical Care: Results of a Stratified Randomized Study. Neurol Educ. 2023 Sep 25; 2(3):e200087. PMID: 39359712; PMCID: PMC11419300.
      Citations:    
    15. Kalkach Aparicio M, Lazaridis C. Conceptualizing Consciousness: a Change in Perspective: The Elephant Still Surprises Those only Touching Its Trunk. Phys Med Rehabil Clin N Am. 2024 Feb; 35(1):1-13. PMID: 37993181.
      Citations: 1     Fields:    Translation:HumansAnimals
    16. Lazaridis C, Foreman B. Management Strategies Based on Multi-Modality Neuromonitoring in Severe Traumatic Brain Injury. Neurotherapeutics. 2023 Oct; 20(6):1457-1471. PMID: 37491682; PMCID: PMC10684466.
      Citations: 6     Fields:    Translation:Humans
    17. Lazaridis C. Informed Consent and Decision-Making for Patients with Acquired Cognitive Impairment. Neurol Clin. 2023 08; 41(3):433-442. PMID: 37407097.
      Citations: 2     Fields:    Translation:Humans
    18. Lazaridis C. Permanent Cerebral Circulatory Arrest Is Necessary and Sufficient for Normothermic Regional Perfusion. Crit Care Med. 2023 04 01; 51(4):e95-e96. PMID: 36928017.
      Citations:    Fields:    
    19. Mansour A, Rowell S, Powla PP, Horowitz P, Goldenberg FD, Lazaridis C. Comparative Effectiveness of Intracranial Pressure Monitoring vs No Monitoring in Severe Penetrating Brain Injury Management. JAMA Netw Open. 2023 03 01; 6(3):e231077. PMID: 36961466; PMCID: PMC10313150.
      Citations: 1     Fields:    Translation:Humans
    20. Eversmann C, Shah A, Lazaridis C, Ross LF. Coding the Dead: Cardiopulmonary Resuscitation for Organ Preservation. AJOB Empir Bioeth. 2023; 14(3):167-173. PMID: 36854130.
      Citations:    Fields:    Translation:Humans
    21. Godoy DA, Rubiano AM, Paranhos J, Robba C, Lazaridis C. Avoiding brain hypoxia in severe traumatic brain injury in settings with limited resources - A pathophysiological guide. J Crit Care. 2023 06; 75:154260. PMID: 36773368.
      Citations: 2     Fields:    Translation:Humans
    22. Lazaridis C. Cerebral Circulatory Arrest and the Dead Donor Rule. Am J Bioeth. 2023 02; 23(2):43-45. PMID: 36681913.
      Citations:    Fields:    Translation:Humans
    23. Alvarado-Dyer R, Chesnut RM, Videtta W, Fischer D, Jibaja M, Godoy DA, Garcia RM, Goldenberg FD, Lazaridis C, Aguilera S. Managing Severe Traumatic Brain Injury Across Resource Settings: Latin American Perspectives. Neurocrit Care. 2023 04; 38(2):229-234. PMID: 36635495; PMCID: PMC9836742.
      Citations: 1     Fields:    Translation:Humans
    24. Lazaridis C, Ajith A, Mansour A, Okonkwo DO, Diaz-Arrastia R, Mayampurath A. Prediction of Intracranial Hypertension and Brain Tissue Hypoxia Utilizing High-Resolution Data from the BOOST-II Clinical Trial. Neurotrauma Rep. 2022; 3(1):473-478. PMID: 36337077; PMCID: PMC9622207.
      Citations: 4     
    25. Zakrison TL, Essig R, Polcari A, McKinley W, Arnold D, Beyene R, Wilson K, Rogers S, Matthews JB, Millis JM, Angelos P, O'Connor M, Mansour A, Goldenberg F, Spiegel T, Horowitz P, Das P, Slidell M, Chokshi N, Okeke I, Barth R, Wilkins HE, Kass-Hout T, Lazaridis C. Review Paper on Penetrating Brain Injury: Ethical Quandaries in the Trauma Bay and Beyond. Ann Surg. 2023 Jan 01; 277(1):66-72. PMID: 35997268; PMCID: PMC9762724.
      Citations: 2     Fields:    Translation:Humans
    26. Lazaridis C. Brain Shock-Toward Pathophysiologic Phenotyping in Traumatic Brain Injury. Crit Care Explor. 2022 Jul; 4(7):e0724. PMID: 35815183; PMCID: PMC9257295.
      Citations: 7     
    27. Lazaridis C. Normothermic regional perfusion: Ethically not merely permissible but recommended. Am J Transplant. 2022 09; 22(9):2285-2286. PMID: 35451186.
      Citations:    Fields:    Translation:Humans
    28. Lazaridis C. In Reply to the Letter to the Editor Regarding "Decompressive Craniectomy After Traumatic Brain Injury: Incorporating Patient Preferences into Decision Making". World Neurosurg. 2022 04; 160:124. PMID: 35364669.
      Citations:    Fields:    
    29. Loggini A, Kass-Hout T, Awad IA, El Ammar F, Kramer CL, Goldenberg FD, Lazaridis C, Mansour A. Case Report: Management of Traumatic Carotid-Cavernous Fistulas in the Acute Setting of Penetrating Brain Injury. Front Neurol. 2021; 12:715955. PMID: 35222224; PMCID: PMC8879509.
      Citations:    
    30. Omelianchuk A, Bernat J, Caplan A, Greer D, Lazaridis C, Lewis A, Pope T, Ross LF, Magnus D. Revise the Uniform Determination of Death Act to Align the Law With Practice Through Neurorespiratory Criteria. Neurology. 2022 03 29; 98(13):532-536. PMID: 35078943; PMCID: PMC8967425.
      Citations: 12     Fields:    Translation:Humans
    31. Tangonan R, Alvarado-Dyer R, Loggini A, Ammar FE, Kumbhani R, Lazaridis C, Kramer C, Goldenberg FD, Mansour A. Frequency, Risk Factors, and Outcomes of Unplanned Readmission to the Neurological Intensive Care Unit after Spontaneous Intracerebral Hemorrhage. Neurocrit Care. 2022 10; 37(2):390-398. PMID: 35072926.
      Citations: 2     Fields:    Translation:Humans
    32. Lazaridis C. Defining Death Behind the Veil of Ignorance. J Clin Ethics. 2022; 33(2):130-140. PMID: 35731817.
      Citations:    Fields:    Translation:Humans
    33. Mansour A, Fuhrman JD, Ammar FE, Loggini A, Davis J, Lazaridis C, Kramer C, Goldenberg FD, Giger ML. Machine Learning for Early Detection of Hypoxic-Ischemic Brain Injury After Cardiac Arrest. Neurocrit Care. 2022 06; 36(3):974-982. PMID: 34873672; PMCID: PMC8647961.
      Citations: 7     Fields:    Translation:Humans
    34. Lazaridis C. Comment on "Worse Than Death: Survey of Public Perceptions of Disability Outcomes After Hypothetical Traumatic Brain Injury". Ann Surg. 2021 12 01; 274(6):e722-e723. PMID: 32541214.
      Citations:    Fields:    Translation:Humans
    35. Lazaridis C, Goldenberg FD, Mansour A, Kramer C, Tate A. What Does Coma Mean? Implications for Shared Decision Making in Acute Brain Injury. World Neurosurg. 2022 02; 158:e377-e385. PMID: 34763107.
      Citations: 1     Fields:    Translation:Humans
    36. Lazaridis C, Mansour A, Singh M. Decompressive Craniectomy After Traumatic Brain Injury: Incorporating Patient Preferences into Decision-Making. World Neurosurg. 2022 01; 157:e327-e332. PMID: 34648983.
      Citations:    Fields:    Translation:Humans
    37. Mansour A, Loggini A, El Ammar F, Alvarado-Dyer R, Polster S, Stadnik A, Das P, Warnke PC, Yamini B, Lazaridis C, Kramer C, Mould WA, Hildreth M, Sharrock M, Hanley DF, Goldenberg FD, Awad IA. Post-Trial Enhanced Deployment and Technical Performance with the MISTIE Procedure per Lessons Learned. J Stroke Cerebrovasc Dis. 2021 Sep; 30(9):105996. PMID: 34303090; PMCID: PMC8384714.
      Citations:    Fields:    Translation:Humans
    38. Lazaridis C, Mansour A, Alvarado-Dyer R, Tangonan R, Loggini A, Kramer C, Goldenberg FD. Civilian Firearm-Inflicted Brain Injury: Coagulopathy, Vascular Injuries, and Triage. Curr Neurol Neurosci Rep. 2021 07 10; 21(9):47. PMID: 34244864.
      Citations:    Fields:    Translation:Humans
    39. Lazaridis C. Brain-Lung Conflicts and Patterns of Mechanical Ventilation. Crit Care Med. 2021 07 01; 49(7):1200-1202. PMID: 34135278.
      Citations:    Fields:    
    40. Loggini A, Mansour A, El Ammar F, Tangonan R, Kramer CL, Goldenberg FD, Lazaridis C. Inversion of T Waves on Admission is Associated with Mortality in Spontaneous Intracerebral Hemorrhage. J Stroke Cerebrovasc Dis. 2021 Jun; 30(6):105776. PMID: 33839377.
      Citations: 2     Fields:    Translation:Humans
    41. Loggini A, Mansour A, El Ammar F, Lazaridis C, Kramer CL, Bulwa Z, Saleh Velez F, McCoy C, Goldenberg FD. Early Determinants of Neurocritical Care Unit Length of Stay in Patients with Spontaneous Intracerebral Hemorrhage. Neurocrit Care. 2021 04; 34(2):485-491. PMID: 32651738.
      Citations: 1     Fields:    Translation:Humans
    42. Lazaridis C, Mansour A. To Decompress or Not? An Expected Utility Inspired Approach To Shared decision-making For Supratentorial Ischemic Stroke. Neurocrit Care. 2021 06; 34(3):709-713. PMID: 33604879.
      Citations: 1     Fields:    Translation:Humans
    43. Loggini A, El Ammar F, Darzi AJ, Mansour A, Kramer CL, Goldenberg FD, Lazaridis C. Effect of desmopressin on hematoma expansion in antiplatelet-associated intracerebral hemorrhage: A systematic review and meta-analysis. J Clin Neurosci. 2021 Apr; 86:116-121. PMID: 33775314.
      Citations: 4     Fields:    Translation:Humans
    44. Lazaridis C, Johnson LSM. Determination of Brain Death. JAMA. 2021 02 02; 325(5):492. PMID: 33528532.
      Citations:    Fields:    Translation:Humans
    45. Lazaridis C. Cerebral Autoregulation: The Concept the Legend the Promise. Neurocrit Care. 2021 06; 34(3):717-719. PMID: 33495911.
      Citations: 3     Fields:    Translation:Humans
    46. Lazaridis C, Desai M, Johnson LSM. Communication and Well-Being Considerations in Disorders of Consciousness. Neurocrit Care. 2021 04; 34(2):701-703. PMID: 33479918.
      Citations: 2     Fields:    Translation:Humans
    47. Mansour A, Loggini A, Goldenberg FD, Kramer C, Naidech AM, Ammar FE, Vasenina V, Castro B, Das P, Horowitz PM, Karrison T, Zakrison T, Hampton D, Rogers SO, Lazaridis C. Coagulopathy as a Surrogate of Severity of Injury in Penetrating Brain Injury. J Neurotrauma. 2021 Jun 01; 38(13):1821-1826. PMID: 33238820; PMCID: PMC9208722.
      Citations: 4     Fields:    Translation:Humans
    48. Loggini A, Ammar FE, Awad IA, Lazaridis C, Kramer CL, Kordeck C, McKoy C, Goldenberg FD, Mansour A. Temporal Evolution and Outcomes of Non-Traumatic Intracerebral Hemorrhage in Hospitalized Patients. J Stroke Cerebrovasc Dis. 2021 Mar; 30(3):105584. PMID: 33412398; PMCID: PMC9249439.
      Citations:    Fields:    Translation:Humans
    49. Lazaridis C. Defining Death: Reasonableness and Legitimacy. J Clin Ethics. 2021; 32(2):109-113. PMID: 34129526.
      Citations: 2     Fields:    Translation:Humans
    50. Zeiler FA, Ercole A, Cabeleira M, Beqiri E, Menon DK, Lazaridis C, Smielewski P, Czosnyka M, CENTER-TBI High Resolution ICU Sub-Study Participants and Investigators, Zoerle T, Carbonara M, Stocchetti N. Patient-specific ICP Epidemiologic Thresholds in Adult Traumatic Brain Injury: A CENTER-TBI Validation Study. J Neurosurg Anesthesiol. 2021 Jan; 33(1):28-38. PMID: 31219937.
      Citations: 22     Fields:    Translation:Humans
    51. Loggini A, Tangonan R, El Ammar F, Mansour A, Kramer CL, Lazaridis C, Goldenberg FD. Neuroendocrine Dysfunction in the Acute Setting of Penetrating Brain Injury: A Systematic Review. World Neurosurg. 2021 03; 147:172-180.e1. PMID: 33346052.
      Citations:    Fields:    Translation:Humans
    52. Godoy DA, Lazaridis C, Badenes R, Rovegno M. The effects of arterial CO2 on the injured brain: Two faces of the same coin. J Crit Care. 2021 02; 61:207-215. PMID: 33186827.
      Citations: 7     Fields:    Translation:Humans
    53. Loggini A, El Ammar F, Mansour A, Kramer CL, Goldenberg FD, Lazaridis C. Association between electrolyte levels at presentation and hematoma expansion and outcome in spontaneous intracerebral hemorrhage: A systematic review. J Crit Care. 2021 02; 61:177-185. PMID: 33181414.
      Citations: 9     Fields:    Translation:Humans
    54. Mansour A, Loggini A, El Ammar F, Ginat D, Awad IA, Lazaridis C, Kramer C, Vasenina V, Polster SP, Huang A, Olivera Perez H, Das P, Horowitz PM, Zakrison T, Hampton D, Rogers SO, Goldenberg FD. Cerebrovascular Complications in Early Survivors of Civilian Penetrating Brain Injury. Neurocrit Care. 2021 06; 34(3):918-926. PMID: 33025542; PMCID: PMC9159343.
      Citations: 5     Fields:    Translation:Humans
    55. Sivakumar S, Lazaridis C. Bioreactance-Based Noninvasive Fluid Responsiveness and Cardiac Output Monitoring: A Pilot Study in Patients with Aneurysmal Subarachnoid Hemorrhage and Literature Review. Crit Care Res Pract. 2020; 2020:2748181. PMID: 33014461; PMCID: PMC7512079.
      Citations: 1     
    56. Trifan G, Goldenberg FD, Caprio FZ, Biller J, Schneck M, Khaja A, Terna T, Brorson J, Lazaridis C, Bulwa Z, Alvarado Dyer R, Saleh Velez FG, Prabhakaran S, Liotta EM, Batra A, Reish NJ, Ruland S, Teitcher M, Taylor W, De la Pena P, Conners JJ, Grewal PK, Pinna P, Dafer RM, Osteraas ND, DaSilva I, Hall JP, John S, Shafi N, Miller K, Moustafa B, Vargas A, Gorelick PB, Testai FD. Characteristics of a Diverse Cohort of Stroke Patients with SARS-CoV-2 and Outcome by Sex. J Stroke Cerebrovasc Dis. 2020 Nov; 29(11):105314. PMID: 32951959; PMCID: PMC7486061.
      Citations: 16     Fields:    Translation:HumansPHPublic Health
    57. Lazaridis C. Deciding Under Uncertainty: The Case of Refractory Intracranial Hypertension. Front Neurol. 2020; 11:908. PMID: 32973664; PMCID: PMC7468512.
      Citations:    
    58. Lazaridis C, Goldenberg FD. Intracranial Pressure in Traumatic Brain Injury: From Thresholds to Heuristics. Crit Care Med. 2020 08; 48(8):1210-1213. PMID: 32697493.
      Citations: 6     Fields:    Translation:Humans
    59. Lazaridis C. Accommodating Apnea Testing Not Death Determination Refusal. Am J Bioeth. 2020 06; 20(6):47-49. PMID: 32618509.
      Citations: 3     Fields:    Translation:Humans
    60. Lazaridis C, Desai M, Damoulakis G, Zeiler FA. Intracranial Pressure Threshold Heuristics in Traumatic Brain Injury: One, None, Many! Neurocrit Care. 2020 06; 32(3):672-676. PMID: 32141033.
      Citations: 6     Fields:    Translation:Humans
    61. Lazaridis C, Goldenberg FD. Intracranial Pressure in Traumatic Brain Injury: From Thresholds to Heuristics. Crit Care Med. 2020 Apr 28. PMID: 32345832.
      Citations:    
    62. Loggini A, Tangonan R, El Ammar F, Mansour A, Goldenberg FD, Kramer CL, Lazaridis C. The role of amantadine in cognitive recovery early after traumatic brain injury: A systematic review. Clin Neurol Neurosurg. 2020 07; 194:105815. PMID: 32244036.
      Citations: 14     Fields:    Translation:Humans
    63. Suarez JI, Martin RH, Bauza C, Georgiadis A, Venkatasubba Rao CP, Calvillo E, Hemphill JC, Sung G, Oddo M, Taccone FS, LeRoux PD, PRINCE Study Investigators. Worldwide Organization of Neurocritical Care: Results from the PRINCE Study Part 1. Neurocrit Care. 2020 02; 32(1):172-179. PMID: 31175567; PMCID: PMC7223982.
      Citations: 19     Fields:    Translation:Humans
    64. Loggini A, Vasenina VI, Mansour A, Das P, Horowitz PM, Goldenberg FD, Kramer C, Lazaridis C. Management of civilians with penetrating brain injury: A systematic review. J Crit Care. 2020 04; 56:159-166. PMID: 31923862.
      Citations: 13     Fields:    Translation:Humans
    65. Lazaridis C. Intracranial Pressure Monitoring in Traumatic Brain Injury: Start Ventricular or Parenchymal? Neurocrit Care. 2019 08; 31(1):22-23. PMID: 31025185.
      Citations:    Fields:    Translation:Humans
    66. Lazaridis C. Withdrawal of Life-Sustaining Treatments in Perceived Devastating Brain Injury: The Key Role of Uncertainty. Neurocrit Care. 2019 02; 30(1):33-41. PMID: 30143963.
      Citations: 18     Fields:    Translation:Humans
    67. Lazaridis C. Letter to the Editor. Reanalyze BEST TRIP. J Neurosurg. 2019 01 18; 131(2):652. PMID: 30660126.
      Citations:    Fields:    Translation:Humans
    68. Lazaridis C. End-of-life Considerations and Shared Decision Making in Neurocritical Care. Continuum (Minneap Minn). 2018 12; 24(6):1794-1799. PMID: 30516607.
      Citations: 4     Fields:    Translation:Humans
    69. Lazaridis C, Altaweel L, Karakitsos D. Updates in Neurocritical Care. Crit Care Res Pract. 2018; 2018:1617359. PMID: 30155293; PMCID: PMC6093028.
      Citations:    
    70. Lazaridis C, Rusin CG, Robertson CS. Secondary brain injury: Predicting and preventing insults. Neuropharmacology. 2019 02; 145(Pt B):145-152. PMID: 29885419.
      Citations: 44     Fields:    Translation:Humans
    71. Lazaridis C. Brain Injured and Heart Strained. Crit Care Med. 2018 06; 46(6):1023-1024. PMID: 29762407.
      Citations:    Fields:    Translation:Humans
    72. Soliman I, Johnson GGRJ, Gillman LM, Zeiler FA, Faqihi F, Aletreby WT, Balhamar A, Mahmood NN, Ahmad Mumtaz S, Alharthy A, Lazaridis C, Karakitsos D. New Optic Nerve Sonography Quality Criteria in the Diagnostic Evaluation of Traumatic Brain Injury. Crit Care Res Pract. 2018; 2018:3589762. PMID: 29854448; PMCID: PMC5952494.
      Citations: 15     
    73. Kazmi SO, Sivakumar S, Karakitsos D, Alharthy A, Lazaridis C. Cerebral Pathophysiology in Extracorporeal Membrane Oxygenation: Pitfalls in Daily Clinical Management. Crit Care Res Pract. 2018; 2018:3237810. PMID: 29744226; PMCID: PMC5878897.
      Citations: 28     
    74. Okonkwo DO, Shutter LA, Moore C, Temkin NR, Puccio AM, Madden CJ, Andaluz N, Chesnut RM, Bullock MR, Grant GA, McGregor J, Weaver M, Jallo J, LeRoux PD, Moberg D, Barber J, Lazaridis C, Diaz-Arrastia RR. Brain Oxygen Optimization in Severe Traumatic Brain Injury Phase-II: A Phase II Randomized Trial. Crit Care Med. 2017 Nov; 45(11):1907-1914. PMID: 29028696; PMCID: PMC5679063.
      Citations: 156     Fields:    Translation:HumansCTClinical Trials
    75. Fam MD, Zeineddine HA, Eliyas JK, Stadnik A, Jesselson M, McBee N, Lane K, Cao Y, Wu M, Zhang L, Thompson RE, John S, Ziai W, Hanley DF, Awad IA, CLEAR III Trial Investigators. CSF inflammatory response after intraventricular hemorrhage. Neurology. 2017 Oct 10; 89(15):1553-1560. PMID: 28887375; PMCID: PMC5634667.
      Citations: 23     Fields:    Translation:HumansCellsCTClinical Trials
    76. Lazaridis C. Ending Life in the ICU: The Vacuity of Sanctity. Crit Care Med. 2017 06; 45(6):e628. PMID: 28509755.
      Citations:    Fields:    Translation:Humans
    77. Koch PM, Lazaridis C. What does it mean for a critically ill patient to fare well? Intensive Care Med. 2017 10; 43(10):1518-1519. PMID: 28500453.
      Citations: 2     Fields:    Translation:Humans
    78. Lazaridis C. Resuscitation Versus Donation: Conflict, Priority, and Rational Consent. Am J Bioeth. 2017 05; 17(5):27-29. PMID: 28430062.
      Citations:    Fields:    Translation:Humans
    79. Sivakumar S, Taccone FS, Rehman M, Hinson H, Naval N, Lazaridis C. Hemodynamic and neuro-monitoring for neurocritically ill patients: An international survey of intensivists. J Crit Care. 2017 06; 39:40-47. PMID: 28171804.
      Citations: 10     Fields:    Translation:Humans
    80. Raza SM, Lazaridis C, Olivi A, Quiñones-Hinojosa A. Olfactory Groove Meningiomas: Acute Presentation and Potential : Pitfalls in Management and Functional Restoration. Acta Neurochir Suppl. 2017; 124:155-158. PMID: 28120068.
      Citations:    Fields:    Translation:Humans
    81. Lazaridis C. Diffusion Hypoxia and/or Primary Mitochondrial Failure? JAMA Neurol. 2016 11 01; 73(11):1372-1373. PMID: 27618519.
      Citations: 1     Fields:    Translation:HumansCells
    82. Lazaridis C. Cerebral oxidative metabolism failure in traumatic brain injury: "Brain shock". J Crit Care. 2017 02; 37:230-233. PMID: 27773372.
      Citations: 13     Fields:    Translation:HumansCells
    83. Lazaridis C, Robertson CS. The Role of Multimodal Invasive Monitoring in Acute Traumatic Brain Injury. Neurosurg Clin N Am. 2016 Oct; 27(4):509-17. PMID: 27637400.
      Citations: 15     Fields:    Translation:Humans
    84. Myers RB, Lazaridis C, Jermaine CM, Robertson CS, Rusin CG. Predicting Intracranial Pressure and Brain Tissue Oxygen Crises in Patients With Severe Traumatic Brain Injury. Crit Care Med. 2016 09; 44(9):1754-61. PMID: 27315192; PMCID: PMC7083460.
      Citations: 18     Fields:    Translation:Humans
    85. Lazaridis C, Robertson CS. Hypothermia for Increased Intracranial Pressure: Is It Dead? Curr Neurol Neurosci Rep. 2016 09; 16(9):78. PMID: 27443645.
      Citations: 4     Fields:    Translation:HumansAnimals
    86. Lazaridis C. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. N Engl J Med. 2016 04 07; 374(14):1384. PMID: 27050214.
      Citations: 4     Fields:    Translation:Humans
    87. Blumenthal-Barby JS, Lazaridis C. A Woman in Her 30s Whose Family Becomes Distrustful After an Initial Prognosis Proves Inaccurate. Chest. 2016 Apr; 149(4):e115-7. PMID: 27055715.
      Citations:    Fields:    Translation:Humans
    88. Lazaridis C. Transforming ICU death into life-radically more. Intensive Care Med. 2016 Dec; 42(12):2096-2097. PMID: 27000387.
      Citations: 1     Fields:    Translation:Humans
    89. Lazaridis C, Smielewski P, Menon DK, Hutchinson P, Pickard JD, Czosnyka M. Patient-Specific Thresholds and Doses of Intracranial Hypertension in Severe Traumatic Brain Injury. Acta Neurochir Suppl. 2016; 122:117-20. PMID: 27165889.
      Citations: 5     Fields:    Translation:Humans
    90. Lazaridis C, Yang M, DeSantis SM, Luo ST, Robertson CS. Predictors of intensive care unit length of stay and intracranial pressure in severe traumatic brain injury. J Crit Care. 2015 Dec; 30(6):1258-62. PMID: 26324412; PMCID: PMC5040122.
      Citations: 12     Fields:    Translation:Humans
    91. Lazaridis C. "No-touch" period: no benefit for donors, high cost for recipients. Intensive Care Med. 2016 Jan; 42(1):134. PMID: 26179430.
      Citations: 1     Fields:    Translation:Humans
    92. Lazaridis C, Maas AI, Souter MJ, Martin RH, Chesnut RM, DeSantis SM, Sung G, Leroux PD, Suarez JI, Second Neurocritical Care Research Conference Investigators. Alternative clinical trial design in neurocritical care. Neurocrit Care. 2015 Jun; 22(3):378-84. PMID: 25894451.
      Citations: 1     Fields:    Translation:Humans
    93. Citerio G, Park S, Schmidt JM, Moberg R, Suarez JI, Le Roux PD, Second Neurocritical Care Research Conference Investigators. Data collection and interpretation. Neurocrit Care. 2015 Jun; 22(3):360-8. PMID: 25846711.
      Citations: 8     Fields:    Translation:Humans
    94. Georgiadis AL, Palesch YY, Zygun D, Hemphill JC, Robertson CS, Leroux PD, Suarez JI, Second Neurocritical Care Research Conference Investigators. Multi-modality neuro-monitoring: conventional clinical trial design. Neurocrit Care. 2015 Jun; 22(3):369-77. PMID: 25832350.
      Citations:    Fields:    Translation:Humans
    95. Frontera J, Ziai W, O'Phelan K, Leroux PD, Kirkpatrick PJ, Diringer MN, Suarez JI, Second Neurocritical Care Research Conference Investigators. Regional brain monitoring in the neurocritical care unit. Neurocrit Care. 2015 Jun; 22(3):348-59. PMID: 25832349.
      Citations: 8     Fields:    Translation:Humans
    96. Lazaridis C. Routine recovery of organs for transplantation can be acceptable. Intensive Care Med. 2015 Jun; 41(6):1152. PMID: 25971376.
      Citations: 3     Fields:    Translation:Humans
    97. Bershad EM, Rao CP, Vuong KD, Mazabob J, Brown G, Styron SL, Nguyen T, Delledera E, Smirnakis SM, Lazaridis C, Georgiadis AL, Mokracek M, Seipel TJ, Nisbet JJ, Baskaran V, Chang AH, Stewart P, Suarez JI. Multidisciplinary protocol for rapid head computed tomography turnaround time in acute stroke patients. J Stroke Cerebrovasc Dis. 2015 Jun; 24(6):1256-61. PMID: 25920753.
      Citations: 3     Fields:    Translation:Humans
    98. Shah V, Lazaridis C. Apnea testing on extracorporeal membrane oxygenation: Case report and literature review. J Crit Care. 2015 Aug; 30(4):784-6. PMID: 25891646.
      Citations: 10     Fields:    Translation:Humans
    99. Lazaridis C. Where was I when I was in a coma? Intensive Care Med. 2015 Nov; 41(11):1971-2. PMID: 25711472.
      Citations:    Fields:    Translation:Humans
    100. Lazaridis C, Blumenthal-Barby JS. Organ Donation Beyond Brain Death: Donors as Ends and Maximal Utility. Am J Bioeth. 2015; 15(8):17-9. PMID: 26225507.
      Citations: 1     Fields:    Translation:Humans
    101. Lazaridis C, Blumenthal-Barby JS. Biology, metaphysics, and brain death criteria. J Crit Care. 2015 Apr; 30(2):417-8. PMID: 25599946.
      Citations:    Fields:    Translation:Humans
    102. Lazaridis C, Andrews CM. Brain tissue oxygenation, lactate-pyruvate ratio, and cerebrovascular pressure reactivity monitoring in severe traumatic brain injury: systematic review and viewpoint. Neurocrit Care. 2014 Oct; 21(2):345-55. PMID: 24993955.
      Citations: 8     Fields:    Translation:Humans
    103. Lazaridis C. The living brain dead. Intensive Care Med. 2014 Nov; 40(11):1791. PMID: 25186985.
      Citations:    Fields:    Translation:Humans
    104. Lazaridis C. From targeting to optimizing cerebral perfusion pressure. Crit Care Med. 2014 Sep; 42(9):e635. PMID: 25126820.
      Citations:    Fields:    Translation:Humans
    105. Lazaridis C, Czosnyka M. Patient-specific intracranial pressure. Response. J Neurosurg. 2014 Apr; 120(4):892. PMID: 24809078.
      Citations: 2     Fields:    Translation:Humans
    106. Lazaridis C, Andrews CM. Traumatic spinal cord injury: learn from the brain!*. Crit Care Med. 2014 Mar; 42(3):749-50. PMID: 24534971.
      Citations: 4     Fields:    Translation:Humans
    107. Lazaridis C, DeSantis SM, Smielewski P, Menon DK, Hutchinson P, Pickard JD, Czosnyka M. Patient-specific thresholds of intracranial pressure in severe traumatic brain injury. J Neurosurg. 2014 Apr; 120(4):893-900. PMID: 24506248.
      Citations: 46     Fields:    Translation:Humans
    108. Desantis SM, Lazaridis C, Ji S, Spinale FG. Analyzing Propensity Matched Zero-Inflated Count Outcomes in Observational Studies. J Appl Stat. 2014 Jan 01; 41(1). PMID: 24298197; PMCID: PMC3843491.
      Citations: 7     
    109. Lazaridis C. Plateau waves of intracranial pressure and mechanisms of brain hypoxia. J Crit Care. 2014 Apr; 29(2):303-4. PMID: 24411105.
      Citations: 2     Fields:    Translation:Humans
    110. DeSantis SM, Lazaridis C. Aprotinin revisited. Intensive Care Med. 2014 Jan; 40(1):142. PMID: 24154674; PMCID: PMC5038918.
      Citations:    Fields:    Translation:Humans
    111. Graffagnino C, Bergese S, Love J, Schneider D, Lazaridis C, LaPointe M, Lee K, Lynch G, Hu MY, Williams GC. Clevidipine rapidly and safely reduces blood pressure in acute intracerebral hemorrhage: the ACCELERATE trial. Cerebrovasc Dis. 2013; 36(3):173-80. PMID: 24135526.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    112. Madey JJ, Hannah JA, Lazaridis C. Central pontine myelinolysis following acute hypoglycemia. Clin Neurol Neurosurg. 2013 Oct; 115(10):2299-300. PMID: 23948485.
      Citations: 4     Fields:    Translation:Humans
    113. Desantis SM, Lazaridis C, Palesch Y, Ramakrishnan V. Regression analysis of ordinal stroke clinical trial outcomes: an application to the NINDS t-PA trial. Int J Stroke. 2014 Feb; 9(2):226-31. PMID: 23803174; PMCID: PMC5042689.
      Citations: 8     Fields:    Translation:Humans
    114. Lazaridis C, Neyens R, Bodle J, DeSantis SM. High-osmolarity saline in neurocritical care: systematic review and meta-analysis. Crit Care Med. 2013 May; 41(5):1353-60. PMID: 23591212.
      Citations: 17     Fields:    Translation:Humans
    115. Lazaridis C, Smielewski P, Steiner LA, Brady KM, Hutchinson P, Pickard JD, Czosnyka M. Optimal cerebral perfusion pressure: are we ready for it? Neurol Res. 2013 Mar; 35(2):138-48. PMID: 23452576.
      Citations: 20     Fields:    Translation:Humans
    116. Turk AS, Nyberg EM, Chaudry MI, Turner RD, Magarik JA, Nicholas JS, Holmstedt CA, Chalela JA, Hays A, Lazaridis C, Chimowitz MI, Turan TN, Adams RJ, Jauch EC. Utilization of CT perfusion patient selection for mechanical thrombectomy irrespective of time: a comparison of functional outcomes and complications. J Neurointerv Surg. 2013 Nov; 5(6):518-22. PMID: 22935349.
      Citations: 8     Fields:    Translation:Humans
    117. Lazaridis C, Czosnyka M. Cerebral blood flow, brain tissue oxygen, and metabolic effects of decompressive craniectomy. Neurocrit Care. 2012 Jun; 16(3):478-84. PMID: 22396191.
      Citations: 16     Fields:    Translation:Humans
    118. Lazaridis C, DeSantis SM, Vandergrift AW, Krishna V. Cerebral blood flow velocity changes and the value of the pulsatility index post decompressive craniectomy. J Clin Neurosci. 2012 Jul; 19(7):1052-4. PMID: 22555129.
      Citations: 4     Fields:    Translation:Humans
    119. Adams RJ, Debenham E, Chalela J, Chimowitz M, Hays A, Hill C, Holmstedt C, Jauch E, Kitch A, Lazaridis C, Turan TN. REACH MUSC: A Telemedicine Facilitated Network for Stroke: Initial Operational Experience. Front Neurol. 2012; 3:33. PMID: 22435064; PMCID: PMC3303157.
      Citations: 10     
    120. Krishna V, Lazaridis C, Ellegala D, Glazier S, Kindy M, Spampinato M, Chalela JA. Spinal cord infarction associated with subarachnoid hemorrhage. Clin Neurol Neurosurg. 2012 Sep; 114(7):1030-2. PMID: 22386902; PMCID: PMC3703243.
      Citations: 4     Fields:    Translation:Humans
    121. Lazaridis C. Advanced hemodynamic monitoring: principles and practice in neurocritical care. Neurocrit Care. 2012 Feb; 16(1):163-9. PMID: 21678100.
      Citations: 10     Fields:    Translation:Humans
    122. Lazaridis C, DeSantis SM, Jauch EC, Adams RJ. Telestroke in South Carolina. J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):946-50. PMID: 22196873.
      Citations: 10     Fields:    Translation:Humans
    123. Lazaridis C, DeSantis SM, McLawhorn M, Krishna V. Liberation of neurosurgical patients from mechanical ventilation and tracheostomy in neurocritical care. J Crit Care. 2012 Aug; 27(4):417.e1-8. PMID: 22033050.
      Citations: 9     Fields:    Translation:Humans
    124. Turk A, Magarik JA, Chaudry I, Turner RD, Nicholas J, Holmstedt CA, Chalela J, Hays A, Lazaridis C, Jauch E, Chimowitz M, Turan T, Adams R. CT perfusion-guided patient selection for endovascular treatment of acute ischemic stroke is safe and effective. J Neurointerv Surg. 2012 Jul; 4(4):261-5. PMID: 21990520.
      Citations: 15     Fields:    Translation:Humans
    125. Lazaridis C, Bodle J, Chaudry I, Hays A, Chalela J. Familial nontraumatic, nonaneurysmal subarachnoid hemorrhage: a report on three first-degree siblings. J Neurosurg. 2011 Sep; 115(3):621-3. PMID: 21639697.
      Citations: 2     Fields:    Translation:Humans
    126. Hays AN, Lazaridis C, Neyens R, Nicholas J, Gay S, Chalela JA. Osmotherapy: use among neurointensivists. Neurocrit Care. 2011 Apr; 14(2):222-8. PMID: 21153930.
      Citations: 33     Fields:    Translation:Humans
    127. Lazaridis C, Pradilla G, Nyquist PA, Tamargo RJ. Intra-aortic balloon pump counterpulsation in the setting of subarachnoid hemorrhage, cerebral vasospasm, and neurogenic stress cardiomyopathy. Case report and review of the literature. Neurocrit Care. 2010 Aug; 13(1):101-8. PMID: 20383610.
      Citations: 13     Fields:    Translation:Humans
    128. Lazaridis C, Naval N. Risk factors and medical management of vasospasm after subarachnoid hemorrhage. Neurosurg Clin N Am. 2010 Apr; 21(2):353-64. PMID: 20380975.
      Citations: 9     Fields:    Translation:Humans
    129. Aravapalli A, Fox J, Lazaridis C. Cerebral fat embolism and the "starfield" pattern: a case report. Cases J. 2009 Nov 19; 2:212. PMID: 19946456; PMCID: PMC2783161.
      Citations: 6     
    130. Chik Y, Hoesch RE, Lazaridis C, Weisman CJ, Llinas RH. A case of postpartum cerebral angiopathy with subarachnoid hemorrhage. Nat Rev Neurol. 2009 Sep; 5(9):512-6. PMID: 19724301.
      Citations: 5     Fields:    Translation:Humans
    131. Lazaridis C, Hays AN, Neyens R, Chalela JA. Liberation from mechanical ventilation in the neurocritically ill. Crit Care Med. 2009 Apr; 37(4):1531; author reply 1532. PMID: 19318858.
      Citations:    Fields:    Translation:Humans
    132. Stevens RD, Lazaridis C, Chalela JA. The role of mechanical ventilation in acute brain injury. Neurol Clin. 2008 May; 26(2):543-63, x. PMID: 18514826.
      Citations: 20     Fields:    Translation:Humans
    133. Singer MA, Lazaridis C, Nations SP, Wolfe GI. Reversible nitrous oxide-induced myeloneuropathy with pernicious anemia: case report and literature review. Muscle Nerve. 2008 Jan; 37(1):125-9. PMID: 17623854.
      Citations: 22     Fields:    Translation:HumansCells
    134. Lazaridis C, Geocadin R, Mirski M. An association between hypernatremia, adverse cardiac outcomes and mortality in patients with subarachnoid hemorrhage. Neurocrit Care. 2007; 7(3):270-1; author reply 272. PMID: 17975712.
      Citations:    Fields:    Translation:Humans
    135. Lazaridis C, Torabi A, Cannon S. Bilateral third nerve palsy and temporal arteritis. Arch Neurol. 2005 Nov; 62(11):1766-8. PMID: 16286553.
      Citations: 13     Fields:    Translation:Humans
    136. Pavlidis TE, Atmatzidis KS, Lazaridis CN, Papaziogas BT, Makris JG, Papaziogas TB. Comparison between modern mesh and conventional non-mesh methods of inguinal hernia repair. Minerva Chir. 2002 Feb; 57(1):7-12. PMID: 11832851.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
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