"Galactosylceramides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cerebrosides which contain as their polar head group a galactose moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in beta-galactosidase, is the cause of galactosylceramide lipidosis or globoid cell leukodystrophy.
| Descriptor ID |
D005699
|
| MeSH Number(s) |
D02.065.313.250.450 D09.400.410.420.525.200.250.450 D10.390.470.675.200.250.450 D10.570.877.360.612.200.250.450
|
| Concept/Terms |
Galactosylceramides- Galactosylceramides
- Galactosyl Ceramides
- Ceramides, Galactosyl
- Galactocerebrosides
|
Below are MeSH descriptors whose meaning is more general than "Galactosylceramides".
Below are MeSH descriptors whose meaning is more specific than "Galactosylceramides".
This graph shows the total number of publications written about "Galactosylceramides" by people in this website by year, and whether "Galactosylceramides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
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Below are the most recent publications written about "Galactosylceramides" by people in Profiles.
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Efficacy of ABX196, a new NKT agonist, in prophylactic human vaccination. Vaccine. 2014 Oct 21; 32(46):6138-45.
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Production of a-galactosylceramide by a prominent member of the human gut microbiota. PLoS Biol. 2013 Jul; 11(7):e1001610.
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Expression of CD1c enhances human invariant NKT cell activation by a-GalCer. Cancer Immun. 2013; 13:9.
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The molecular basis for recognition of CD1d/a-galactosylceramide by a human non-Va24 T cell receptor. PLoS Biol. 2012; 10(10):e1001412.
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Scavenger receptors target glycolipids for natural killer T cell activation. J Clin Invest. 2012 Nov; 122(11):3943-54.
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Distinct APCs explain the cytokine bias of a-galactosylceramide variants in vivo. J Immunol. 2012 Apr 01; 188(7):3053-61.
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Impact of sugar stereochemistry on natural killer T cell stimulation by bacterial glycolipids. Org Biomol Chem. 2011 Oct 26; 9(22):7659-62.
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Fatty acid amide hydrolase shapes NKT cell responses by influencing the serum transport of lipid antigen in mice. J Clin Invest. 2010 Jun; 120(6):1873-84.
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Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen alphaGalCer. Proc Natl Acad Sci U S A. 2009 Jun 23; 106(25):10254-9.
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Synthesis of diglycosylceramides and evaluation of their iNKT cell stimulatory properties. Bioorg Med Chem Lett. 2008 May 15; 18(10):3052-5.