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Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia.
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Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia.
Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia. Nat Genet. 1994 Apr; 6(4):335-41.
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PubMed
subject areas
Adult
Biopsy
Cells, Cultured
Combined Modality Therapy
Coronary Artery Bypass
Coronary Disease
Female
Follow-Up Studies
Gene Expression Regulation
Genes, Synthetic
Genetic Therapy
Genetic Vectors
Humans
Hyperlipoproteinemia Type II
In Situ Hybridization, Fluorescence
Lipoproteins, HDL
Lipoproteins, LDL
Liver
Lovastatin
Receptors, LDL
Recombinant Proteins
Safety
Up-Regulation