Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan-Kynurenine-Aryl Hydrocarbon Axis.

Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan-Kynurenine-Aryl Hydrocarbon Axis. Clin Cancer Res. 2019 03 01; 25(5):1462-1471.

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subject areas

Cell Line, Tumor
Computational Biology
Enzyme Inhibitors
Gene Expression Profiling
Humans
Immunomodulation
Immunotherapy
Indoleamine-Pyrrole 2,3,-Dioxygenase
Kynurenine
Models, Biological
Neoplasms
Receptors, Aryl Hydrocarbon
Signal Transduction
Transcriptome
Tryptophan