Receptors, Aryl Hydrocarbon
"Receptors, Aryl Hydrocarbon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
| Descriptor ID |
D018336
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| MeSH Number(s) |
D12.776.260.643.715 D12.776.826.209.715 D12.776.930.760
|
| Concept/Terms |
Receptors, Aryl Hydrocarbon- Receptors, Aryl Hydrocarbon
- Aryl Hydrocarbon Receptor
- Receptor, Aryl Hydrocarbon
- Aryl Hydrocarbon Receptors
- Dioxin Receptor
- Receptor, Dioxin
- Dioxin Receptors
- Receptors, Dioxin
- Polyaromatic Hydrocarbon Receptors
- Polyaromatic Hydrocarbon Receptor
- Receptor, Polyaromatic Hydrocarbon
- Receptors, Polyaromatic Hydrocarbon
- TCDD Receptor
- Receptor, TCDD
- Receptors, TCDD
- TCDD Receptors
- AH Receptor
- Receptor, AH
- AH Receptors
- Receptors, AH
- Receptors, 2,3,7,8-Tetrachlorodibenzo-p-dioxin
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Aryl Hydrocarbon".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Aryl Hydrocarbon".
This graph shows the total number of publications written about "Receptors, Aryl Hydrocarbon" by people in this website by year, and whether "Receptors, Aryl Hydrocarbon" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptors, Aryl Hydrocarbon" by people in Profiles.
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Potential Dietary and Therapeutic Strategies Involving Indole-3-Carbinole in Preclinical Models of Intestinal Inflammation. Nutrients. 2023 Nov 30; 15(23).
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Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food. Cell Rep. 2023 10 31; 42(10):113153.
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IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation. Front Immunol. 2021; 12:678999.
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Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan-Kynurenine-Aryl Hydrocarbon Axis. Clin Cancer Res. 2019 03 01; 25(5):1462-1471.
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Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics. Transl Psychiatry. 2018 01 10; 8(1):10.
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AhR ligand Aminoflavone inhibits a6-integrin expression and breast cancer sphere-initiating capacity. Cancer Lett. 2016 06 28; 376(1):53-61.
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Innate Lymphoid Cells Control Early Colonization Resistance against Intestinal Pathogens through ID2-Dependent Regulation of the Microbiota. Immunity. 2015 Apr 21; 42(4):731-43.
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Loss of sirtuin 1 (SIRT1) disrupts skin barrier integrity and sensitizes mice to epicutaneous allergen challenge. J Allergy Clin Immunol. 2015 Apr; 135(4):936-945.e4.
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PCB 126 and other dioxin-like PCBs specifically suppress hepatic PEPCK expression via the aryl hydrocarbon receptor. PLoS One. 2012; 7(5):e37103.
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Transcription factor c-Maf mediates the TGF-ß-dependent suppression of IL-22 production in T(H)17 cells. Nat Immunol. 2011 Oct 16; 12(12):1238-45.