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Discovery of potent and selective sirtuin 2 (SIRT2) inhibitors using a fragment-based approach.
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Discovery of potent and selective sirtuin 2 (SIRT2) inhibitors using a fragment-based approach.
Discovery of potent and selective sirtuin 2 (SIRT2) inhibitors using a fragment-based approach. J Med Chem. 2014 Oct 23; 57(20):8340-57.
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PubMed
subject areas
Animals
Dogs
Drug Design
Drug Discovery
Drug Evaluation, Preclinical
Enzyme Inhibitors
Humans
Ligands
Madin Darby Canine Kidney Cells
MCF-7 Cells
Molecular Structure
Niacinamide
Sirtuin 2
Structure-Activity Relationship
Sulfonic Acids
Suramin
authors with profiles
Daniel J. Wilson