"Fucosyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes catalyzing the transfer of fucose from a nucleoside diphosphate fucose to an acceptor molecule which is frequently another carbohydrate, a glycoprotein, or a glycolipid molecule. Elevated activity of some fucosyltransferases in human serum may serve as an indicator of malignancy. The class includes EC 2.4.1.65; EC 2.4.1.68; EC 2.4.1.69; EC 2.4.1.89.
| Descriptor ID |
D005647
|
| MeSH Number(s) |
D08.811.913.400.450.300
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Fucosyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Fucosyltransferases".
This graph shows the total number of publications written about "Fucosyltransferases" by people in this website by year, and whether "Fucosyltransferases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fucosyltransferases" by people in Profiles.
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A Combination of Structural, Genetic, Phenotypic and Enzymatic Analyses Reveals the Importance of a Predicted Fucosyltransferase to Protein O-Glycosylation in the Bacteroidetes. Biomolecules. 2021 11 30; 11(12).
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FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses. Nat Commun. 2020 12 16; 11(1):6398.
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Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 09 18; 8(1):578.
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Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness. Nature. 2014 Oct 30; 514(7524):638-41.
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CD15-expressing nodular lymphocyte-predominant Hodgkin lymphoma. Histopathology. 2011 Apr; 58(5):803-5.
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Fucose removal from complex-type oligosaccharide enhances the antibody-dependent cellular cytotoxicity of single-gene-encoded antibody comprising a single-chain antibody linked the antibody constant region. J Immunol Methods. 2005 Nov 30; 306(1-2):93-103.
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The effects of brefeldin-A on the high mannose oligosaccharides of mouse thyrotropin, free alpha-subunits, and total glycoproteins. Endocrinology. 1988 Jul; 123(1):310-8.