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Alexander Chervonsky

TitleProfessor
InstitutionUniversity of Chicago
DepartmentPathology
AddressChicago IL 60637
Email
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    Collapse Research 
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    R21AI186365     (CHERVONSKY, ALEXANDER V)Jul 2, 2024 - May 31, 2026
    NIH
    Alpha defensins: innate keepers of host-commensal homeostasis
    Role: Principal Investigator
    R01AI158744     (CHERVONSKY, ALEXANDER V)Sep 17, 2021 - Aug 31, 2026
    NIH
    Enhancement of autoimmunity in type 1 diabetes by gluten
    Role: Principal Investigator
    R01AI127411     (CHERVONSKY, ALEXANDER V)Aug 16, 2017 - Nov 30, 2027
    NIH
    Host's and microbiota's contribution to sexual dimorphism of autoimmunity
    Role: Principal Investigator
    R21AI115683     (CHERVONSKY, ALEXANDER V)Dec 1, 2014 - Nov 30, 2017
    NIH
    Diet and microbiota in type 1 diabetes
    Role: Principal Investigator
    R21AI105821     (CHERVONSKY, ALEXANDER V)Apr 1, 2014 - Mar 31, 2017
    NIH
    Commensal microbes and sexual dimorphism in autoimmunity
    Role: Principal Investigator
    R01DK090422     (CHERVONSKY, ALEXANDER V)Jul 1, 2011 - Jun 30, 2017
    NIH
    Intravital Imaging of Type I Diabetes
    Role: Principal Investigator
    R01AI082418     (CHERVONSKY, ALEXANDER V)May 15, 2010 - May 31, 2021
    NIH
    Type 1 diabetes: the role of commensal microbiota
    Role: Principal Investigator
    R01AI072627     (CHERVONSKY, ALEXANDER V)Jan 1, 2007 - Dec 31, 2012
    NIH
    Fas in host defense and autoimmune diseases
    Role: Principal Investigator
    R13AI062200     (CHERVONSKY, ALEXANDER V)Sep 15, 2004 - Aug 31, 2005
    NIH
    Workshop on Antigen Processing and Presentation
    Role: Principal Investigator
    R01DK066264     (CHERVONSKY, ALEXANDER V)Feb 1, 2004 - Nov 30, 2010
    NIH
    Genetic Control of Homing of Autoimmune T Cells
    Role: Principal Investigator
    R21DK063452     (CHERVONSKY, ALEXANDER V)Sep 30, 2002 - Jul 31, 2005
    NIH
    Role of Innate Immunity in Type 1 Diabetes
    Role: Principal Investigator
    R01AI052210     (CHERVONSKY, ALEXANDER V)Aug 1, 2002 - May 31, 2008
    NIH
    B Cells and Development of Intestinal Epithelium
    Role: Principal Investigator
    R01AI046782     (CHERVONSKY, ALEXANDER V)Apr 20, 2001 - Mar 31, 2008
    NIH
    Biased Thymic Selection and Consequential Autoimmunity
    Role: Principal Investigator
    R01DK053561     (CHERVONSKY, ALEXANDER V)Apr 1, 1997 - May 31, 2003
    NIH
    ENGINEERING REJECTION-RESISTANT PANCREATIC BETA CELLS
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lee J, Yurkovetskiy LA, Reiman D, Frommer L, Strong Z, Chang A, Kahaly GJ, Khan AA, Chervonsky AV. Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression. Nat Commun. 2024 Sep 03; 15(1):7688. PMID: 39227386; PMCID: PMC11372096.
      Citations: 2     Fields:    Translation:AnimalsCells
    2. Bertrand L, Chervonsky AV, Lehuen A. Innate Immunity in Type 1 Diabetes. Cold Spring Harb Perspect Med. 2024 Jul 29. PMID: 39074873.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Lee J, Reiman D, Singh S, Chang A, Morel L, Chervonsky AV. Microbial influences on severity and sex bias of systemic autoimmunity. Immunol Rev. 2024 08; 325(1):64-76. PMID: 38716867; PMCID: PMC11338725.
      Citations: 1     Fields:    Translation:HumansAnimals
    4. Spring J, Beilinson V, DeFelice BC, Sanchez JM, Fischbach M, Chervonsky A, Golovkina T. Retroviral Infection and Commensal Bacteria Dependently Alter the Metabolomic Profile in a Sterile Organ. Viruses. 2023 01 29; 15(2). PMID: 36851600; PMCID: PMC9967258.
      Citations:    Fields:    Translation:AnimalsCells
    5. Spring J, Beilinson V, DeFelice BC, Sanchez JM, Fischbach M, Chervonsky A, Golovkina T. Retroviral infection and commensal bacteria dependently alter the metabolomic profile in a sterile organ. bioRxiv. 2023 Jan 11. PMID: 36711645; PMCID: PMC9882031.
      Citations:    
    6. Funsten MC, Yurkovetskiy LA, Kuznetsov A, Reiman D, Hansen CHF, Senter KI, Lee J, Ratiu J, Dahal-Koirala S, Antonopoulos DA, Dunny GM, Sollid LM, Serreze D, Khan AA, Chervonsky AV. Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes. Cell Host Microbe. 2023 02 08; 31(2):213-227.e9. PMID: 36603588; PMCID: PMC9911364.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    7. Spring J, Khan AA, Lara S, O'Grady K, Wilks J, Gurbuxani S, Erickson S, Fischbach M, Jacobson A, Chervonsky A, Golovkina T. Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus. Cell Rep. 2022 09 13; 40(11):111341. PMID: 36103821; PMCID: PMC10226680.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    8. Brown J, Abboud G, Ma L, Choi SC, Kanda N, Zeumer-Spataro L, Lee J, Peng W, Cagmat J, Faludi T, Mohamadzadeh M, Garrett T, Mandik-Nayak L, Chervonsky A, Perl A, Morel L. Microbiota-mediated skewing of tryptophan catabolism modulates CD4+ T cells in lupus-prone mice. iScience. 2022 May 20; 25(5):104241. PMID: 35494242; PMCID: PMC9051618.
      Citations: 23     
    9. Lee J, Cullum E, Stoltz K, Bachmann N, Strong Z, Millick DD, Denzin LK, Chang A, Tarakanova V, Chervonsky AV, Golovkina T. Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68. J Immunol. 2021 12 15; 207(12):2944-2951. PMID: 34810225; PMCID: PMC9124240.
      Citations: 3     Fields:    Translation:HumansAnimals
    10. Barreiro LB, Chervonsky A. My Old World chap, this a-gal is not for you. Cell Host Microbe. 2021 03 10; 29(3):315-317. PMID: 33705699.
      Citations:    Fields:    Translation:Animals
    11. Cullum E, Dikiy S, Beilinson HA, Kane M, Veinbachs A, Beilinson VM, Denzin LK, Chervonsky A, Golovkina T. Genetic Control of Neonatal Immune Tolerance to an Exogenous Retrovirus. J Virol. 2020 11 23; 94(24). PMID: 32999021; PMCID: PMC7925187.
      Citations: 1     Fields:    Translation:AnimalsCells
    12. Wan X, Vomund AN, Peterson OJ, Chervonsky AV, Lichti CF, Unanue ER. Publisher Correction: The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides. Nat Immunol. 2020 05; 21(5):589. PMID: 32238948.
      Citations: 1     Fields:    
    13. Dybala MP, Kuznetsov A, Motobu M, Hendren-Santiago BK, Philipson LH, Chervonsky AV, Hara M. Integrated Pancreatic Blood Flow: Bidirectional Microcirculation Between Endocrine and Exocrine Pancreas. Diabetes. 2020 07; 69(7):1439-1450. PMID: 32198213; PMCID: PMC7306124.
      Citations: 51     Fields:    Translation:HumansAnimals
    14. Wan X, Vomund AN, Peterson OJ, Chervonsky AV, Lichti CF, Unanue ER. The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides. Nat Immunol. 2020 04; 21(4):455-463. PMID: 32152506; PMCID: PMC7117798.
      Citations: 48     Fields:    
    15. Jain A, Irizarry-Caro RA, McDaniel MM, Chawla AS, Carroll KR, Overcast GR, Philip NH, Oberst A, Chervonsky AV, Katz JD, Pasare C. T cells instruct myeloid cells to produce inflammasome-independent IL-1ß and cause autoimmunity. Nat Immunol. 2020 01; 21(1):65-74. PMID: 31848486; PMCID: PMC6927526.
      Citations: 51     Fields:    Translation:AnimalsCells
    16. Khan AA, Yurkovetskiy L, O'Grady K, Pickard JM, Antonopoulos DA, Golovkina T, Chervonsky A, de Pooter R. Polymorphic Immune Mechanisms Regulate Commensal Repertoire. Cell Rep. 2019 10 15; 29(3):541-550.e4. PMID: 31618625; PMCID: PMC6904226.
      Citations: 38     Fields:    Translation:AnimalsCells
    17. Kane M, Deiss F, Chervonsky A, Golovkina TV. A Single Locus Controls Interferon Gamma-Independent Antiretroviral Neutralizing Antibody Responses. J Virol. 2018 08 15; 92(16). PMID: 29875252; PMCID: PMC6069202.
      Citations: 3     Fields:    Translation:AnimalsCells
    18. Denzin LK, Khan AA, Virdis F, Wilks J, Kane M, Beilinson HA, Dikiy S, Case LK, Roopenian D, Witkowski M, Chervonsky AV, Golovkina TV. Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob. Immunity. 2017 08 15; 47(2):310-322.e7. PMID: 28813660; PMCID: PMC5568092.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    19. Chervonsky AV. Just a Spoonful of Sugar Helps the Tolerance Go Up. Cell. 2017 06 15; 169(7):1170-1172. PMID: 28622502.
      Citations: 3     Fields:    Translation:AnimalsCells
    20. Yoon J, Leyva-Castillo JM, Wang G, Galand C, Oyoshi MK, Kumar L, Hoff S, He R, Chervonsky A, Oppenheim JJ, Kuchroo VK, van den Brink MR, Malefyt Rde W, Fuhlbrigge R, Rosenstiel P, Terhorst C, Murphy G, Geha RS, Tessier PA. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016 09 19; 213(10):2147-66. PMID: 27551155; PMCID: PMC5032726.
      Citations: 49     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    21. Wilks J, Lien E, Qureshi N, Chervonsky AV, Golovkina TV, Jacobson AN, Fischbach MA. Mammalian Lipopolysaccharide Receptors Incorporated into the Retroviral Envelope Augment Virus Transmission. Cell Host Microbe. 2015 Oct 14; 18(4):456-62. PMID: 26468748; PMCID: PMC4795803.
      Citations: 49     Fields:    Translation:AnimalsCells
    22. Burrows MP, Volchkov P, Kobayashi KS, Chervonsky AV. Microbiota regulates type 1 diabetes through Toll-like receptors. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):9973-7. PMID: 26216961; PMCID: PMC4538618.
      Citations: 92     Fields:    Translation:AnimalsCells
    23. Pickard JM, Chervonsky AV. Intestinal fucose as a mediator of host-microbe symbiosis. J Immunol. 2015 Jun 15; 194(12):5588-93. PMID: 26048966; PMCID: PMC4536407.
      Citations: 93     Fields:    Translation:HumansAnimals
    24. Yurkovetskiy LA, Pickard JM, Chervonsky AV. Microbiota and autoimmunity: exploring new avenues. Cell Host Microbe. 2015 May 13; 17(5):548-52. PMID: 25974297; PMCID: PMC4535992.
      Citations: 58     Fields:    
    25. Pickard JM, Maurice CF, Kinnebrew MA, Abt MC, Schenten D, Golovkina TV, Bogatyrev SR, Ismagilov RF, Pamer EG, Turnbaugh PJ, Chervonsky AV. Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness. Nature. 2014 Oct 30; 514(7524):638-41. PMID: 25274297; PMCID: PMC4214913.
      Citations: 273     Fields:    Translation:AnimalsCells
    26. Rivas FV, Chervonsky AV, Medzhitov R. ART and immunology. Trends Immunol. 2014 Oct; 35(10):451. PMID: 25261059.
      Citations: 13     Fields:    Translation:Humans
    27. Varanasi V, Khan AA, Chervonsky AV. Loss of the death receptor CD95 (Fas) expression by dendritic cells protects from a chronic viral infection. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8559-64. PMID: 24912151; PMCID: PMC4060656.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    28. Wilks J, Beilinson H, Theriault B, Chervonsky A, Golovkina T. Antibody-mediated immune control of a retrovirus does not require the microbiota. J Virol. 2014 Jun; 88(11):6524-7. PMID: 24648456; PMCID: PMC4093894.
      Citations: 6     Fields:    Translation:Animals
    29. Wueest S, Mueller R, Item F, Chin AS, Wiedemann MS, Takizawa H, Kovtonyuk L, Chervonsky AV, Schoenle EJ, Manz MG, Konrad D, Blüher M. Fas (CD95) expression in myeloid cells promotes obesity-induced muscle insulin resistance. EMBO Mol Med. 2014 01; 6(1):43-56. PMID: 24203314; PMCID: PMC3936487.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    30. Yurkovetskiy L, Burrows M, Khan AA, Graham L, Volchkov P, Becker L, Antonopoulos D, Umesaki Y, Chervonsky AV. Gender bias in autoimmunity is influenced by microbiota. Immunity. 2013 Aug 22; 39(2):400-12. PMID: 23973225; PMCID: PMC3822899.
      Citations: 501     Fields:    Translation:AnimalsCells
    31. Chervonsky AV. Microbiota and autoimmunity. Cold Spring Harb Perspect Biol. 2013 Mar 01; 5(3):a007294. PMID: 23457255; PMCID: PMC3578358.
      Citations: 39     Fields:    Translation:HumansCells
    32. Atkinson MA, Chervonsky A. Does the gut microbiota have a role in type 1 diabetes? Early evidence from humans and animal models of the disease. Diabetologia. 2012 Nov; 55(11):2868-77. PMID: 22875196; PMCID: PMC3496388.
      Citations: 43     Fields:    Translation:HumansAnimals
    33. Varanasi V, Avanesyan L, Schumann DM, Chervonsky AV. Cytotoxic mechanisms employed by mouse T cells to destroy pancreatic ß-cells. Diabetes. 2012 Nov; 61(11):2862-70. PMID: 22773667; PMCID: PMC3478530.
      Citations: 25     Fields:    Translation:AnimalsCells
    34. Chervonsky AV. Intestinal commensals: influence on immune system and tolerance to pathogens. Curr Opin Immunol. 2012 Jun; 24(3):255-60. PMID: 22445718.
      Citations: 18     Fields:    Translation:Humans
    35. Chervonsky AV. Solving the plot: early events are the key to diabetes intervention. Nat Immunol. 2012 Mar 19; 13(4):311-2. PMID: 22430775.
      Citations:    Fields:    Translation:AnimalsCells
    36. Chervonsky AV. Microbial influences on immune function and more. Immunol Rev. 2012 Jan; 245(1):7-12. PMID: 22168410.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    37. Allison JP, Benoist C, Chervonsky AV. Nobels: Toll pioneers deserve recognition. Nature. 2011 Nov 09; 479(7372):178. PMID: 22071753.
      Citations: 2     Fields:    
    38. Kane M, Case LK, Kopaskie K, Kozlova A, MacDearmid C, Chervonsky AV, Golovkina TV. Successful transmission of a retrovirus depends on the commensal microbiota. Science. 2011 Oct 14; 334(6053):245-9. PMID: 21998394; PMCID: PMC3519937.
      Citations: 225     Fields:    Translation:AnimalsCells
    39. Rudensky AY, Chervonsky AV. A narrow circle of mutual friends. Immunity. 2011 May 27; 34(5):697-9. PMID: 21616440.
      Citations: 7     Fields:    
    40. Wang Y, Devkota S, Musch MW, Jabri B, Nagler C, Antonopoulos DA, Chervonsky A, Chang EB. Regional mucosa-associated microbiota determine physiological expression of TLR2 and TLR4 in murine colon. PLoS One. 2010 Oct 22; 5(10):e13607. PMID: 21042588; PMCID: PMC2962643.
      Citations: 66     Fields:    Translation:Animals
    41. Chinen T, Volchkov PY, Chervonsky AV, Rudensky AY. A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota. J Exp Med. 2010 Oct 25; 207(11):2323-30. PMID: 20921284; PMCID: PMC2964571.
      Citations: 75     Fields:    Translation:AnimalsCells
    42. Pickard JM, Chervonsky AV. Sampling of the intestinal microbiota by epithelial M cells. Curr Gastroenterol Rep. 2010 Oct; 12(5):331-9. PMID: 20706806.
      Citations: 11     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    43. Scott GS, Fishman S, Khai Siew L, Margalit A, Chapman S, Chervonsky AV, Wen L, Gross G, Wong FS. Immunotargeting of insulin reactive CD8 T cells to prevent diabetes. J Autoimmun. 2010 Dec; 35(4):390-7. PMID: 20850948.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    44. Krebs LT, Starling C, Chervonsky AV, Gridley T. Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants. Genesis. 2010 Mar; 48(3):146-50. PMID: 20101599; PMCID: PMC2849749.
      Citations: 59     Fields:    Translation:AnimalsCells
    45. Lee HK, Mattei LM, Steinberg BE, Alberts P, Lee YH, Chervonsky A, Mizushima N, Grinstein S, Iwasaki A. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 2010 Feb 26; 32(2):227-39. PMID: 20171125; PMCID: PMC2996467.
      Citations: 277     Fields:    Translation:AnimalsCells
    46. Chervonsky AV. Influence of microbial environment on autoimmunity. Nat Immunol. 2010 Jan; 11(1):28-35. PMID: 20016507.
      Citations: 79     Fields:    Translation:HumansAnimals
    47. Wueest S, Rapold RA, Schumann DM, Rytka JM, Schildknecht A, Nov O, Chervonsky AV, Rudich A, Schoenle EJ, Donath MY, Konrad D. Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice. J Clin Invest. 2010 Jan; 120(1):191-202. PMID: 19955656; PMCID: PMC2798678.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    48. Chervonsky A. Innate receptors and microbes in induction of autoimmunity. Curr Opin Immunol. 2009 Dec; 21(6):641-7. PMID: 19747810; PMCID: PMC3833248.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    49. Kamanaka M, Rainbow D, Schuster-Gossler K, Eynon EE, Chervonsky AV, Wicker LS, Flavell RA. Amino acid polymorphisms altering the glycosylation of IL-2 do not protect from type 1 diabetes in the NOD mouse. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):11236-40. PMID: 19549859; PMCID: PMC2700154.
      Citations: 8     Fields:    Translation:AnimalsCells
    50. Wen L, Ley RE, Volchkov PY, Stranges PB, Avanesyan L, Stonebraker AC, Hu C, Wong FS, Szot GL, Bluestone JA, Gordon JI, Chervonsky AV. Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature. 2008 Oct 23; 455(7216):1109-13. PMID: 18806780; PMCID: PMC2574766.
      Citations: 994     Fields:    Translation:AnimalsCells
    51. Leiter EH, Reifsnyder P, Driver J, Kamdar S, Choisy-Rossi C, Serreze DV, Hara M, Chervonsky A. Unexpected functional consequences of xenogeneic transgene expression in beta-cells of NOD mice. Diabetes Obes Metab. 2007 Nov; 9 Suppl 2:14-22. PMID: 17919174.
      Citations: 9     Fields:    Translation:AnimalsCells
    52. Stranges PB, Watson J, Cooper CJ, Choisy-Rossi CM, Stonebraker AC, Beighton RA, Hartig H, Sundberg JP, Servick S, Kaufmann G, Fink PJ, Chervonsky AV. Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity. Immunity. 2007 May; 26(5):629-41. PMID: 17509906; PMCID: PMC2575811.
      Citations: 198     Fields:    Translation:AnimalsCells
    53. Schumann DM, Maedler K, Franklin I, Konrad D, Gjinovci A, Kurrer MO, Gauthier BR, Bosco D, Andres A, Berney T, Greter M, Becher B, Chervonsky AV, Halban PA, Mandrup-Poulsen T, Wollheim CB, Donath MY, Størling J, Böni-Schnetzler M. The Fas pathway is involved in pancreatic beta cell secretory function. Proc Natl Acad Sci U S A. 2007 Feb 20; 104(8):2861-6. PMID: 17299038; PMCID: PMC1815272.
      Citations: 27     Fields:    Translation:AnimalsCells
    54. Lee Y, Chin RK, Christiansen P, Sun Y, Tumanov AV, Wang J, Chervonsky AV, Fu YX. Recruitment and activation of naive T cells in the islets by lymphotoxin beta receptor-dependent tertiary lymphoid structure. Immunity. 2006 Sep; 25(3):499-509. PMID: 16934497.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    55. Mach J, Hshieh T, Hsieh D, Grubbs N, Chervonsky A. Development of intestinal M cells. Immunol Rev. 2005 Aug; 206:177-89. PMID: 16048549.
      Citations: 35     Fields:    Translation:HumansAnimals
    56. Logunova NN, Viret C, Pobezinsky LA, Miller SA, Kazansky DB, Sundberg JP, Chervonsky AV. Restricted MHC-peptide repertoire predisposes to autoimmunity. J Exp Med. 2005 Jul 04; 202(1):73-84. PMID: 15998789; PMCID: PMC2212910.
      Citations: 18     Fields:    Translation:AnimalsCells
    57. Murphy KT, Wardak A, Beckett MA, Lopez CA, Mehta N, Kimchi E, Salloum RM, Jaskowiak NT, Posner MC, Ohno T, Kufe DW, Weichselbaum RR, Mauceri HJ. Forphenicinol enhances the antitumor effects of cyclophosphamide in a model of squamous cell carcinoma. Cancer Chemother Pharmacol. 2005 Sep; 56(3):317-21. PMID: 15887016.
      Citations: 1     Fields:    Translation:AnimalsCells
    58. Tumanov AV, Kuprash DV, Mach JA, Nedospasov SA, Chervonsky AV. Lymphotoxin and TNF produced by B cells are dispensable for maintenance of the follicle-associated epithelium but are required for development of lymphoid follicles in the Peyer's patches. J Immunol. 2004 Jul 01; 173(1):86-91. PMID: 15210762.
      Citations: 28     Fields:    Translation:AnimalsCells
    59. Pobezinskaya Y, Chervonsky AV, Golovkina TV. Initial stages of mammary tumor virus infection are superantigen independent. J Immunol. 2004 May 01; 172(9):5582-7. PMID: 15100301.
      Citations: 5     Fields:    Translation:AnimalsCells
    60. Christen U, Darwiche R, Thomas HE, Wolfe T, Rodrigo E, Chervonsky A, Flavell RA, von Herrath MG. Virally induced inflammation triggers fratricide of Fas-ligand-expressing beta-cells. Diabetes. 2004 Mar; 53(3):591-6. PMID: 14988242.
      Citations: 3     Fields:    Translation:AnimalsCells
    61. Schott WH, Haskell BD, Tse HM, Milton MJ, Piganelli JD, Choisy-Rossi CM, Reifsnyder PC, Chervonsky AV, Leiter EH. Caspase-1 is not required for type 1 diabetes in the NOD mouse. Diabetes. 2004 Jan; 53(1):99-104. PMID: 14693703.
      Citations: 28     Fields:    Translation:AnimalsCells
    62. Jude BA, Pobezinskaya Y, Bishop J, Parke S, Medzhitov RM, Chervonsky AV, Golovkina TV. Subversion of the innate immune system by a retrovirus. Nat Immunol. 2003 Jun; 4(6):573-8. PMID: 12730691.
      Citations: 77     Fields:    Translation:AnimalsCells
    63. Savinov AY, Wong FS, Stonebraker AC, Chervonsky AV. Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells. J Exp Med. 2003 Mar 03; 197(5):643-56. PMID: 12615905; PMCID: PMC2193823.
      Citations: 83     Fields:    Translation:AnimalsCells
    64. Purdy A, Case L, Duvall M, Overstrom-Coleman M, Monnier N, Chervonsky A, Golovkina T. Unique resistance of I/LnJ mice to a retrovirus is due to sustained interferon gamma-dependent production of virus-neutralizing antibodies. J Exp Med. 2003 Jan 20; 197(2):233-43. PMID: 12538662; PMCID: PMC2193815.
      Citations: 43     Fields:    Translation:AnimalsCells
    65. Savinov AY, Tcherepanov A, Green EA, Flavell RA, Chervonsky AV. Contribution of Fas to diabetes development. Proc Natl Acad Sci U S A. 2003 Jan 21; 100(2):628-32. PMID: 12525697; PMCID: PMC141047.
      Citations: 30     Fields:    Translation:Animals
    66. Hook LM, Jude BA, Ter-Grigorov VS, Hartley JW, Morse HC, Trainin Z, Toder V, Chervonsky AV, Golovkina TV. Characterization of a novel murine retrovirus mixture that facilitates hematopoiesis. J Virol. 2002 Dec; 76(23):12112-22. PMID: 12414952; PMCID: PMC136857.
      Citations: 10     Fields:    Translation:AnimalsCells
    67. Tumanov A, Kuprash D, Lagarkova M, Grivennikov S, Abe K, Shakhov A, Drutskaya L, Stewart C, Chervonsky A, Nedospasov S. Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues. Immunity. 2002 Sep; 17(3):239-50. PMID: 12354378.
      Citations: 90     Fields:    Translation:AnimalsCells
    68. Savinov AY, Wong FS, Chervonsky AV. IFN-gamma affects homing of diabetogenic T cells. J Immunol. 2001 Dec 01; 167(11):6637-43. PMID: 11714835.
      Citations: 38     Fields:    Translation:AnimalsCells
    69. Golovkina T, Agafonova Y, Kazansky D, Chervonsky A. Diverse repertoire of the MHC class II-peptide complexes is required for presentation of viral superantigens. J Immunol. 2001 Feb 15; 166(4):2244-50. PMID: 11160278.
      Citations: 1     Fields:    Translation:AnimalsCells
    70. Golovkina TV, Shlomchik M, Hannum L, Chervonsky A. Organogenic role of B lymphocytes in mucosal immunity. Science. 1999 Dec 03; 286(5446):1965-8. PMID: 10583962.
      Citations: 96     Fields:    Translation:AnimalsCells
    71. Chervonsky AV. Apoptotic and effector pathways in autoimmunity. Curr Opin Immunol. 1999 Dec; 11(6):684-8. PMID: 10631555.
      Citations: 11     Fields:    Translation:HumansAnimals
    72. Chervonsky AV, Medzhitov RM, Denzin LK, Barlow AK, Rudensky AY, Janeway CA. Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides. Proc Natl Acad Sci U S A. 1998 Aug 18; 95(17):10094-9. PMID: 9707606; PMCID: PMC21467.
      Citations: 11     Fields:    Translation:AnimalsCells
    73. Tan LJ, Ceman S, Chervonsky A, Rodriguez-Paris J, Steck TL, Sant AJ. Late events in the intracellular sorting of major histocompatibility complex class II molecules are regulated by the 80-82 segment of the class II beta chain. Eur J Immunol. 1997 Jun; 27(6):1479-88. PMID: 9209501.
      Citations: 5     Fields:    Translation:AnimalsCells
    74. Janeway CA, Chervonsky AV, Sant'Angelo D. T-cell receptors: is the repertoire inherently MHC-specific? Curr Biol. 1997 May 01; 7(5):R299-300. PMID: 9115392.
      Citations: 5     Fields:    Translation:AnimalsCells
    75. Chervonsky AV, Wang Y, Wong FS, Visintin I, Flavell RA, Janeway CA, Matis LA. The role of Fas in autoimmune diabetes. Cell. 1997 Apr 04; 89(1):17-24. PMID: 9094710.
      Citations: 104     Fields:    Translation:AnimalsCells
    76. Chervonsky AV, Golovkina TV, Ross SR, Janeway CA. Differences in the avidity of TCR interactions with a superantigenic ligand affect negative selection but do not allow positive selection. J Immunol. 1995 Dec 01; 155(11):5115-23. PMID: 7594520.
      Citations: 1     Fields:    Translation:AnimalsCells
    77. Chervonsky AV, Xu J, Barlow AK, Khery M, Flavell RA, Janeway CA. Direct physical interaction involving CD40 ligand on T cells and CD40 on B cells is required to propagate MMTV. Immunity. 1995 Jul; 3(1):139-46. PMID: 7542547.
      Citations: 16     Fields:    Translation:AnimalsCells
    78. Chervonsky A, Sant AJ. In the absence of major histocompatibility complex class II molecules, invariant chain is translocated to late endocytic compartments by autophagy. Eur J Immunol. 1995 Apr; 25(4):911-8. PMID: 7737293.
      Citations:    Fields:    Translation:AnimalsCells
    79. Stebbins CC, Loss GE, Elias CG, Chervonsky A, Sant AJ. The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent. J Exp Med. 1995 Jan 01; 181(1):223-34. PMID: 7807005; PMCID: PMC2191808.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    80. Chervonsky AV, Gordon L, Sant AJ. A segment of the MHC class II beta chain plays a critical role in targeting class II molecules to the endocytic pathway. Int Immunol. 1994 Jul; 6(7):973-82. PMID: 7947465.
      Citations: 14     Fields:    Translation:AnimalsCells
    81. Golovkina TV, Chervonsky A, Prescott JA, Janeway CA, Ross SR. The mouse mammary tumor virus envelope gene product is required for superantigen presentation to T cells. J Exp Med. 1994 Feb 01; 179(2):439-46. PMID: 8294859; PMCID: PMC2191387.
      Citations: 24     Fields:    Translation:AnimalsCells
    82. Golovkina TV, Chervonsky A, Dudley JP, Ross SR. Transgenic mouse mammary tumor virus superantigen expression prevents viral infection. Cell. 1992 May 15; 69(4):637-45. PMID: 1316806.
      Citations: 98     Fields:    Translation:AnimalsCells
    83. Fedoseyeva EV, Apasov SG, Chervonsky AV. Specific T suppressors and cytotoxic T lymphocytes recognize different epitopes on Abbm12 molecule. Immunogenetics. 1990; 32(2):129-33. PMID: 1697846.
      Citations:    Fields:    Translation:AnimalsCells
    84. Neyfakh AA, Serpinskaya AS, Chervonsky AV, Apasov SG, Kazarov AR. Multidrug-resistance phenotype of a subpopulation of T-lymphocytes without drug selection. Exp Cell Res. 1989 Dec; 185(2):496-505. PMID: 2480910.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    85. Chervonsky AV, Faerman AI, Evdonina LV, Jazova AK, Kazarov AR, Gussev AI. A simple metabolic system for selection of hybrid hybridomas (tetradomas) producing bispecific monoclonal antibodies. Mol Immunol. 1988 Sep; 25(9):913-5. PMID: 2463483.
      Citations: 1     Fields:    Translation:HumansCells
    86. Brondz BD, Kahn ES, Chervonsky AV, Isakova VR, Apasov SG, Blandova ZK. Differential genetic requirements for in vivo and in vitro induction of T-killer and T-suppressor cells in the mutant H-2Kb system and the cross-reactivity of the T-killer clones. Exp Clin Immunogenet. 1987; 4(4):211-21. PMID: 2978841.
      Citations: 1     Fields:    Translation:AnimalsCells
    87. Cherapakhin VV, Chervonsky AV, Filatov AV, Rokhlin OV. Monoclonal antibodies against common and Igk-1a allotypic determinants of rat immunoglobulin kappa chain constant domain. Immunol Lett. 1985; 10(3-4):217-21. PMID: 2412955.
      Citations:    Fields:    Translation:Animals
    88. Brondz BD, Abronina IF, Zaiceva MB, Filatov AV, Chervonsky AV. Specific suppressor T-cells immune to antigens of the H-2 complex: receptors, clonal structure, genetic restriction and antigenic markers. Immunol Rev. 1984 Aug; 80:29-76. PMID: 6237977.
      Citations: 3     Fields:    Translation:AnimalsCells
    89. Brondz BD, Karaulov AV, Chervonsky AV, Blandova ZK. Requirement for the location of both appropriate and irrelevant H-2 antigens on the same stimulator cell for unspecific DNA-synthesis inhibition by the H-2-antigen-primed, specific suppressor T cells. Immunogenetics. 1982; 15(2):167-76. PMID: 6460694.
      Citations: 3     Fields:    Translation:AnimalsCells
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