"Genes, MHC Class I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetic loci in the vertebrate major histocompatibility complex which encode polymorphic characteristics not related to immune responsiveness or complement activity, e.g., B loci (chicken), DLA (dog), GPLA (guinea pig), H-2 (mouse), RT-1 (rat), HLA-A, -B, and -C class I genes of man.
| Descriptor ID |
D005805
|
| MeSH Number(s) |
G05.360.340.024.340.610.595 G05.360.340.024.380.500.595 G12.500.500.595
|
| Concept/Terms |
Genes, MHC Class I- Genes, MHC Class I
- MHC Class I Genes
- Class I Genes
- Class I Gene
- Gene, Class I
- Genes, Class I
|
Below are MeSH descriptors whose meaning is more general than "Genes, MHC Class I".
Below are MeSH descriptors whose meaning is more specific than "Genes, MHC Class I".
This graph shows the total number of publications written about "Genes, MHC Class I" by people in this website by year, and whether "Genes, MHC Class I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 0 | 1 |
| 1996 | 2 | 0 | 2 |
| 1997 | 0 | 2 | 2 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 2 | 3 |
| 2000 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Genes, MHC Class I" by people in Profiles.
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Targeting the lipid kinase PIKfyve upregulates surface expression of MHC class I to augment cancer immunotherapy. Proc Natl Acad Sci U S A. 2023 Dec 05; 120(49):e2314416120.
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Sex-specific differences in peripheral blood leukocyte transcriptional response to LPS are enriched for HLA region and X chromosome genes. Sci Rep. 2021 01 13; 11(1):1107.
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HLA Class I Supertype Associations With Clinical Outcome of Secondary Dengue Virus Infections in Ethnic Thais. J Infect Dis. 2015 Sep 15; 212(6):939-47.
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High diversity of MIC genes in non-human primates. Immunogenetics. 2014 Oct; 66(9-10):581-7.
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The MHC class I genes of zebrafish. Dev Comp Immunol. 2014 Sep; 46(1):11-23.
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Multiple divergent haplotypes express completely distinct sets of class I MHC genes in zebrafish. Immunogenetics. 2014 Mar; 66(3):199-213.
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MHC-class I-restricted CD4 T cells: a nanomolar affinity TCR has improved anti-tumor efficacy in vivo compared to the micromolar wild-type TCR. Cancer Immunol Immunother. 2013 Feb; 62(2):359-69.
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The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant Vd1 TCR. Eur J Immunol. 2012 Sep; 42(9):2505-10.
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Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma. Nat Genet. 2011 May; 43(5):455-8.
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Immunogenetics of Toxoplasma gondii informs vaccine design. Trends Parasitol. 2010 Nov; 26(11):550-5.