"Hardness" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The mechanical property of material that determines its resistance to force. HARDNESS TESTS measure this property.
Descriptor ID |
D006244
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MeSH Number(s) |
G01.374.647
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hardness".
Below are MeSH descriptors whose meaning is more specific than "Hardness".
This graph shows the total number of publications written about "Hardness" by people in this website by year, and whether "Hardness" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2009 | 0 | 2 | 2 |
2010 | 0 | 2 | 2 |
2013 | 0 | 2 | 2 |
2015 | 0 | 3 | 3 |
2016 | 0 | 2 | 2 |
2017 | 0 | 4 | 4 |
2018 | 0 | 1 | 1 |
2022 | 0 | 2 | 2 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hardness" by people in Profiles.
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Understanding the roles of compaction pressure and crystal hardness on powder tabletability through bonding area - Bonding strength interplay. Int J Pharm. 2024 Jun 25; 659:124253.
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An extended macroindentation method for determining the hardness of poorly compressible materials. Int J Pharm. 2022 Aug 25; 624:122054.
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Mechanisms of Crystal Plasticization by Lattice Water. Pharm Res. 2022 Dec; 39(12):3113-3122.
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Systematic evaluation of common lubricants for optimal use in tablet formulation. Eur J Pharm Sci. 2018 May 30; 117:118-127.
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Dependence of Friability on Tablet Mechanical Properties and a Predictive Approach for Binary Mixtures. Pharm Res. 2017 Dec; 34(12):2901-2909.
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Expedited Development of Diphenhydramine Orally Disintegrating Tablet through Integrated Crystal and Particle Engineering. Mol Pharm. 2017 10 02; 14(10):3399-3408.
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The suitability of common compressibility equations for characterizing plasticity of diverse powders. Int J Pharm. 2017 Oct 30; 532(1):124-130.
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Dependence of Punch Sticking on Compaction Pressure-Roles of Particle Deformability and Tablet Tensile Strength. J Pharm Sci. 2017 08; 106(8):2060-2067.
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Effect of moisture sorption on the performance of crospovidone. Int J Pharm. 2016 Nov 30; 514(1):322-331.
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Mechanical Properties and Tableting Behavior of Amorphous Solid Dispersions. J Pharm Sci. 2017 01; 106(1):217-223.