Solid-Phase Synthesis Techniques
"Solid-Phase Synthesis Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques used to synthesize chemicals using molecular substrates that are bound to a solid surface. Typically a series of reactions are conducted on the bound substrate that results in either the covalent attachment of specific moieties or the modification of existing function groups. These techniques offer an advantage to those involving solution reactions in that the substrate compound does not have to be isolated and purified between the reaction steps.
Descriptor ID |
D060327
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MeSH Number(s) |
E05.197.500 J01.897.836.249.500
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Concept/Terms |
Solid-Phase Synthesis Techniques- Solid-Phase Synthesis Techniques
- Solid Phase Synthesis Techniques
- Solid-Phase Synthesis Technique
- Synthesis Technique, Solid-Phase
- Synthesis Techniques, Solid-Phase
- Technique, Solid-Phase Synthesis
- Techniques, Solid-Phase Synthesis
- Solid-Phase Synthesis Methods
- Method, Solid-Phase Synthesis
- Methods, Solid-Phase Synthesis
- Solid Phase Synthesis Methods
- Solid-Phase Synthesis Method
- Synthesis Method, Solid-Phase
- Synthesis Methods, Solid-Phase
Solid-Phase Synthesis- Solid-Phase Synthesis
- Solid Phase Synthesis
- Solid-Phase Syntheses
- Syntheses, Solid-Phase
- Synthesis, Solid-Phase
- Synthesis, Solid Phase
Solid-Phase Peptide Synthesis- Solid-Phase Peptide Synthesis
- Peptide Syntheses, Solid-Phase
- Solid Phase Peptide Synthesis
- Solid-Phase Peptide Syntheses
- Syntheses, Solid-Phase Peptide
- Synthesis, Solid-Phase Peptide
- Peptide Synthesis, Solid-Phase
- Peptide Synthesis, Solid Phase
Solid-Phase Nucleotide Synthesis- Solid-Phase Nucleotide Synthesis
- Nucleotide Syntheses, Solid-Phase
- Nucleotide Synthesis, Solid-Phase
- Solid Phase Nucleotide Synthesis
- Solid-Phase Nucleotide Syntheses
- Syntheses, Solid-Phase Nucleotide
- Synthesis, Solid-Phase Nucleotide
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Below are MeSH descriptors whose meaning is more general than "Solid-Phase Synthesis Techniques".
Below are MeSH descriptors whose meaning is more specific than "Solid-Phase Synthesis Techniques".
This graph shows the total number of publications written about "Solid-Phase Synthesis Techniques" by people in this website by year, and whether "Solid-Phase Synthesis Techniques" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2011 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Solid-Phase Synthesis Techniques" by people in Profiles.
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Scope and Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin. Chemistry. 2017 Jan 31; 23(7):1709-1716.
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Obviation of hydrogen fluoride in Boc chemistry solid phase peptide synthesis of peptide-athioesters. Chem Commun (Camb). 2016 Nov 29; 52(97):13979-13982.
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Bringing the science of proteins into the realm of organic chemistry: total chemical synthesis of SEP (synthetic erythropoiesis protein). Angew Chem Int Ed Engl. 2013 Nov 11; 52(46):11988-96.
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Automated solid-phase synthesis of RNA oligonucleotides containing a nonbridging phosphorodithioate linkage via phosphorothioamidites. J Org Chem. 2012 Nov 02; 77(21):9889-92.
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Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin. Angew Chem Int Ed Engl. 2012 Jan 23; 51(4):993-9.