"Phosphatidylinositols" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to the hexahydroxy alcohol, myo-inositol. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid, myo-inositol, and 2 moles of fatty acids.
| Descriptor ID |
D010716
|
| MeSH Number(s) |
D10.570.755.375.760.400.942
|
| Concept/Terms |
Phosphatidylinositols- Phosphatidylinositols
- Inositol Phosphoglycerides
- Phosphoglycerides, Inositol
- Inositol Phospholipids
- Phospholipids, Inositol
- Phosphatidyl Inositol
- Inositol, Phosphatidyl
- Phosphoinositides
- PtdIns
- Inositide Phospholipids
- Phospholipids, Inositide
- Phosphatidylinositol
|
Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositols".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylinositols".
This graph shows the total number of publications written about "Phosphatidylinositols" by people in this website by year, and whether "Phosphatidylinositols" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphatidylinositols" by people in Profiles.
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Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM. Nat Struct Mol Biol. 2018 01; 25(1):53-60.
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Mutations of AKT3 are associated with a wide spectrum of developmental disorders including extreme megalencephaly. Brain. 2017 Oct 01; 140(10):2610-2622.
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Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis. PLoS One. 2016; 11(5):e0152869.
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Daclatasvir inhibits hepatitis C virus NS5A motility and hyper-accumulation of phosphoinositides. Virology. 2015 Feb; 476:168-179.
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A human phospholipid phosphatase activated by a transmembrane control module. J Lipid Res. 2012 Nov; 53(11):2266-74.
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Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance. Nature. 2008 Feb 21; 451(7181):964-9.
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A modelling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells II: input-output analysis. J Theor Biol. 2005 Aug 21; 235(4):504-20.
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Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. Cell. 2005 Feb 11; 120(3):343-55.
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Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release. J Biol Chem. 2000 May 19; 275(20):15343-9.
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In vitro proton and phosphorus NMR spectroscopic analysis of murine (C57Bl/6J) brain development. NMR Biomed. 1999 Nov; 12(7):463-70.