"Monensin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts' development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.
| Descriptor ID |
D008985
|
| MeSH Number(s) |
D03.383.312.600
|
| Concept/Terms |
Monensin Sodium- Monensin Sodium
- Monensin Monosodium Salt
- Monensin-A-Sodium Complex
- Monensin A Sodium Complex
|
Below are MeSH descriptors whose meaning is more general than "Monensin".
Below are MeSH descriptors whose meaning is more specific than "Monensin".
This graph shows the total number of publications written about "Monensin" by people in this website by year, and whether "Monensin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Monensin" by people in Profiles.
-
Effect of antibiotic monensin on cell proliferation and IGF1R signaling pathway in human colorectal cancer cells. Ann Med. 2023 12; 55(1):954-964.
-
Wnt signaling inhibition by monensin results in a period of Hippo pathway activation during intestinal adaptation in zebrafish. Am J Physiol Gastrointest Liver Physiol. 2019 06 01; 316(6):G679-G691.
-
Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway. Sci Rep. 2018 12 17; 8(1):17914.
-
Antibiotic monensin synergizes with EGFR inhibitors and oxaliplatin to suppress the proliferation of human ovarian cancer cells. Sci Rep. 2015 Dec 07; 5:17523.
-
Vesicle trafficking plays a novel role in erythroblast enucleation. Blood. 2010 Oct 28; 116(17):3331-40.
-
Cholesterol movement in Niemann-Pick type C cells and in cells treated with amphiphiles. J Biol Chem. 2000 Jun 09; 275(23):17468-75.
-
Continuous and transient vesicle cycling at a ribbon synapse. J Neurosci. 1998 Nov 01; 18(21):8614-24.
-
Degradation of connexin43 gap junctions involves both the proteasome and the lysosome. Exp Cell Res. 1997 Nov 01; 236(2):482-92.
-
The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus. J Cell Biol. 1996 May; 133(4):733-47.
-
Sodium as a mediator of non-phorbol tumor promoter action. Down-modulation of the epidermal growth factor receptor by palytoxin. J Biol Chem. 1989 Sep 05; 264(25):14668-73.