"4-Butyrolactone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
| Descriptor ID |
D015107
|
| MeSH Number(s) |
D02.540.150 D03.383.312.150
|
| Concept/Terms |
4-Butyrolactone- 4-Butyrolactone
- 4 Butyrolactone
- Dihydro-2(3H)-furanone
- gamma-Butyrolactone
- gamma Butyrolactone
- Furanone, tetrahydro-2-
- Furanone, tetrahydro 2
- 1,4-Butanolide
- 1,4 Butanolide
- 4-Hydroxybutyric Acid Lactone
- 4 Hydroxybutyric Acid Lactone
- Lactone, 4-Hydroxybutyric Acid
|
Below are MeSH descriptors whose meaning is more general than "4-Butyrolactone".
Below are MeSH descriptors whose meaning is more specific than "4-Butyrolactone".
This graph shows the total number of publications written about "4-Butyrolactone" by people in this website by year, and whether "4-Butyrolactone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "4-Butyrolactone" by people in Profiles.
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PTGES/PGE2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model. Oncogene. 2020 04; 39(15):3179-3194.
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Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study. Lancet Oncol. 2018 04; 19(4):521-536.
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The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer. PLoS Pathog. 2017 Jul; 13(7):e1006504.