"Lobeline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
| Descriptor ID |
D008120
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| MeSH Number(s) |
D03.132.478 D03.383.621.418
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lobeline".
Below are MeSH descriptors whose meaning is more specific than "Lobeline".
This graph shows the total number of publications written about "Lobeline" by people in this website by year, and whether "Lobeline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lobeline" by people in Profiles.
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Conformational changes in acetylcholine binding protein investigated by temperature accelerated molecular dynamics. PLoS One. 2014; 9(2):e88555.
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Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivo. J Neurochem. 2013 Oct; 127(2):187-98.
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Lobelane decreases methamphetamine self-administration in rats. Eur J Pharmacol. 2007 Sep 24; 571(1):33-8.
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Lobeline, a potential pharmacotherapy for drug addiction, binds to mu opioid receptors and diminishes the effects of opioid receptor agonists. Drug Alcohol Depend. 2007 Jul 10; 89(2-3):282-91.
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Lobeline augments and inhibits cocaine-induced hyperactivity in rats. Life Sci. 2006 Aug 01; 79(10):981-90.
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Analysis of postinspiratory activity of phrenic motoneurons with chemical and vagal reflexes. J Appl Physiol (1985). 1986 Oct; 61(4):1499-509.