"Ofloxacin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
| Descriptor ID |
D015242
|
| MeSH Number(s) |
D03.633.100.810.835.322.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ofloxacin".
Below are MeSH descriptors whose meaning is more specific than "Ofloxacin".
This graph shows the total number of publications written about "Ofloxacin" by people in this website by year, and whether "Ofloxacin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ofloxacin" by people in Profiles.
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Treatment with a neutrophil elastase inhibitor and ofloxacin reduces P. aeruginosa burden in a mouse model of chronic suppurative otitis media. NPJ Biofilms Microbiomes. 2021 04 06; 7(1):31.
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Aqueous and vitreous penetration of linezolid and levofloxacin after oral administration. J Ocul Pharmacol Ther. 2010 Dec; 26(6):579-86.
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Differential effects of levofloxacin and ciprofloxacin on the risk for isolation of quinolone-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2006 Jun; 50(6):2192-6.
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Extending the limits of fingertip composite grafting with moist-exposed dressing. Int Wound J. 2005 Dec; 2(4):315-21.
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Vitritis and chorioretinitis in a patient with West Nile virus infection. Arch Ophthalmol. 2003 Feb; 121(2):205-7.
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Contribution of topoisomerase IV and DNA gyrase mutations in Streptococcus pneumoniae to resistance to novel fluoroquinolones. Antimicrob Agents Chemother. 1999 Aug; 43(8):2000-4.
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Management of fluoroquinolone resistance in Pseudomonas aeruginosa--outcome of monitored use in a referral hospital. Int J Antimicrob Agents. 1998 Aug; 10(3):207-14.
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Feasibility of outpatient management of fever in cancer patients with low-risk neutropenia: results of a prospective randomized trial. Am J Med. 1995 Mar; 98(3):224-31.
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In vitro activity of ofloxacin, ciprofloxacin, and cefoperazone alone and in combination against Xanthomonas maltophilia. Drugs. 1995; 49 Suppl 2:246-9.
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Activity of twenty-one antimicrobial agents including l-ofloxacin against quinolone-sensitive and -resistant, and methicillin-sensitive and -resistant Staphylococcus aureus. Chemotherapy. 1994 Jan-Feb; 40(1):21-5.