Oncogene Protein p21(ras)
"Oncogene Protein p21(ras)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumors. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D015689
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| MeSH Number(s) |
D08.811.277.040.330.300.400.500.300 D12.644.360.525.500.300 D12.776.157.325.515.500.300 D12.776.476.525.500.300 D12.776.624.664.520.750.710 D12.776.964.700.750.710 D12.776.964.775.750.710
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| Concept/Terms |
Oncogene Protein p21(ras)- Oncogene Protein p21(ras)
- p21 Transforming Viral Protein
- p21 v-H-ras
- p21 v H ras
- v-H-ras, p21
- p21(v-H-ras)
- p21 v-Ki-ras
- p21 v Ki ras
- v-Ki-ras, p21
- p21 v-ras
- p21 v ras
- v-ras, p21
- ras Oncogene p21 Product
- ras Oncogene Product p21
- p21 v-Ha-ras
- p21 v Ha ras
- v-Ha-ras, p21
- p21(v-Ha-ras)
- p21(v-K-ras)
- ras Oncogene Protein p21
- p21(v-Ki-ras)
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Below are MeSH descriptors whose meaning is more general than "Oncogene Protein p21(ras)".
Below are MeSH descriptors whose meaning is more specific than "Oncogene Protein p21(ras)".
This graph shows the total number of publications written about "Oncogene Protein p21(ras)" by people in this website by year, and whether "Oncogene Protein p21(ras)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oncogene Protein p21(ras)" by people in Profiles.
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Pharmacologic inactivation of kinase suppressor of Ras1 sensitizes epidermal growth factor receptor and oncogenic Ras-dependent tumors to ionizing radiation treatment. Mol Cancer Ther. 2010 Oct; 9(10):2724-36.
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Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. Food Chem Toxicol. 2009 Jul; 47(7):1430-6.
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Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma. Clin Cancer Res. 2006 Nov 15; 12(22):6611-6.
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Cancer: More than skin deep. Nature. 2003 Feb 06; 421(6923):594-5.
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Enhanced growth of primary tumors in cancer-prone mice after immunization against the mutant region of an inherited oncoprotein. J Exp Med. 2000 Jun 05; 191(11):1945-56.
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Oncogenes in melanomas. J Dermatol. 1992 Nov; 19(11):853-67.
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Ras transformation of cloned rat embryo fibroblasts results in increased rates of protein synthesis and phosphorylation of eukaryotic initiation factor 4E. J Biol Chem. 1992 May 25; 267(15):10659-64.