Gene Rearrangement, B-Lymphocyte, Light Chain
"Gene Rearrangement, B-Lymphocyte, Light Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ordered rearrangement of B-lymphocyte variable gene regions coding for the kappa or lambda IMMUNOGLOBULIN LIGHT CHAINS, thereby contributing to antibody diversity. It occurs during the second stage of differentiation of the IMMATURE B-LYMPHOCYTES.
| Descriptor ID |
D015328
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| MeSH Number(s) |
G05.344.401.601 G12.500.274.601
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| Concept/Terms |
Gene Rearrangement, B-Lymphocyte, Light Chain- Gene Rearrangement, B-Lymphocyte, Light Chain
- B-Cell Light Chain Gene Rearrangement
- B-Lymphocyte Light Chain Gene Rearrangement
- B Cell Light Chain Gene Rearrangement
- B Lymphocyte Light Chain Gene Rearrangement
|
Below are MeSH descriptors whose meaning is more general than "Gene Rearrangement, B-Lymphocyte, Light Chain".
Below are MeSH descriptors whose meaning is more specific than "Gene Rearrangement, B-Lymphocyte, Light Chain".
This graph shows the total number of publications written about "Gene Rearrangement, B-Lymphocyte, Light Chain" by people in this website by year, and whether "Gene Rearrangement, B-Lymphocyte, Light Chain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 2 | 1 | 3 |
| 2002 | 2 | 3 | 5 |
| 2003 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
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Below are the most recent publications written about "Gene Rearrangement, B-Lymphocyte, Light Chain" by people in Profiles.
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Pillars article: generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. Proc. Natl. Acad. Sci. USA, 81: 3180-3184, May 1984. J Immunol. 2008 May 01; 180(9):5765-9.
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Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling. Immunity. 2008 Mar; 28(3):335-45.
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Igkappa allelic inclusion is a consequence of receptor editing. J Exp Med. 2007 Jan 22; 204(1):153-60.
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Regulation of anti-phosphatidylserine antibodies. Immunity. 2003 Feb; 18(2):185-92.
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Recurrent B-cell neoplasms after Rituximab therapy: an immunophenotypic and genotypic study. Leuk Lymphoma. 2002 Dec; 43(12):2335-41.
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Analysis of B cell receptor production and rearrangement. Part I. Light chain rearrangement. Semin Immunol. 2002 Jun; 14(3):169-90; discussion 221-22.
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D is for different-differences between H and L chain rearrangement. Semin Immunol. 2002 Jun; 14(3):239-41.
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Chronic graft-versus-host in Ig knockin transgenic mice abrogates B cell tolerance in anti-double-stranded DNA B cells. J Immunol. 2002 Apr 15; 168(8):4142-53.
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A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling. Immunity. 2002 Feb; 16(2):245-55.
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Editors and editing of anti-DNA receptors. Immunity. 2001 Dec; 15(6):947-57.